Seroprevalence, risk factors and genotype distribution for Hepatitis C infection: A study from rural hospital in Maharashtra.

Abstract:

BACKGROUND AND OBJECTIVES:Hepatitis C is global health problem affecting a significant portion of the world's population. Available data in Western Maharashtra on seroprevalence, risk factors and genotype distribution are very limited. OBJECTIVES:The present study was carried out to estimate the seroprevalence, factors influencing transmission and distribution of genotype of hepatitis C virus (HCV) in a hospital-based population. MATERIALS AND METHODS:This was a cross-sectional, hospital-based study. A total of 25193 serum samples were tested for HCV and HBV infection. All samples from HCV antibody-positive patients were subjected for HCV RNA detection and genotype. Chi-square, unpaired t-test, logistic regression analysis was used for statistical analysis. RESULTS:The seroprevalence for anti-HCV-Ab was 0.46%. Backward multivariate logistic regression analysis revealed increasing age; alcoholic, blood transfusion and dialysis were significant risk factors. Of 116 patients with HCV, 8 (6.89%) patients had HCV-HBV co-infection. The most common genotype (61.90%) was 3 followed by Genotype 1 (38.09%). CONCLUSIONS:In the present study, significant risk factors were a history of blood transfusion, habit of alcohol, dialysis. The prevention of HCV infection can be achieved by screening of blood and blood products and creating awareness about risk factors. Since the efficacy of current and new therapies differ by genotype, genotype study is essential.

journal_name

Indian J Med Microbiol

authors

Patil SR,Datkhile KD,Ghorpade MV,Patil SS,Kakade SV

doi

10.4103/ijmm.IJMM_16_96

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

563-567

issue

4

eissn

0255-0857

issn

1998-3646

pii

IndianJMedMicrobiol_2017_35_4_563_224416

journal_volume

35

pub_type

杂志文章
  • Superantigens - concepts, clinical disease and therapy.

    abstract::The term superantigen was introduced in microbiology and immunology only a decade ago. The unique feature of superantigen is that it bypasses the antigen processing mechanism and specifically binds to TCR v segment and forms a trimolecular complex along with major histocompatibility complex class II. Since its discove...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Hemalatha V,Srikanth P,Mallika M

    更新日期:2004-10-01 00:00:00

  • High prevalence of hepatitis A virus antibody among Bangladeshi children and young adults warrants pre-immunization screening of antibody in HAV vaccination strategy.

    abstract::Serum samples from 465 subjects aged between 1 and 25 years were tested for antibody against hepatitis A virus (HAV) [anti-HAV IgG and IgM] to determine the seroprevalence of HAV antibody and do a cost-benefit analysis for decision making about vaccination against HAV among the general population of Bangladesh. A high...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Ahmed M,Munshi SU,Nessa A,Ullah MS,Tabassum S,Islam MN

    更新日期:2009-01-01 00:00:00

  • Food poisoning due to Salmonella enterica serotype weltevreden in Mangalore.

    abstract::An outbreak of food poisoning due to Salmonella enterica serotype Weltevreden ( S.weltevreden ) involving 34 students has been reported from a tertiary care hospital in Mangalore. The symptoms developed 8-10 hours, after consuming a non- vegetarian dish, probably fish, from an outside caterer. The identity of the orga...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.53211

    authors: Antony B,Dias M,Shetty AK,Rekha B

    更新日期:2009-07-01 00:00:00

  • Human subcutaneous dirofilariasis in India: a report of three cases with brief review of literature.

    abstract::Human subcutaneous dirofilariasis is a rare infection caused by filarial worms of the genus Dirofilaria. The parasites are transmitted to man by mosquitoes and the infection is manifested as subcutaneous nodules. Excision of the lesion is both diagnostic and therapeutic. Hereby we report three cases of human subcutane...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.4103/0255-0857.71836

    authors: Khurana S,Singh G,Bhatti HS,Malla N

    更新日期:2010-10-01 00:00:00

  • One year trends in the gram-negative bacterial antibiotic susceptibility patterns in a medical intensive care unit in South India.

    abstract:PURPOSE:To describe the changes in antibiotic susceptibility patterns of common intensive care unit pathogens with time from the medical intensive care unit of a tertiary care hospital. METHODS:A prospective observational study was conducted in the medical intensive care unit (MICU) of a 2100 bed tertiary care hospita...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.34764

    authors: Kaul S,Brahmadathan KN,Jagannati M,Sudarsanam TD,Pitchamuthu K,Abraham OC,John G

    更新日期:2007-07-01 00:00:00

  • Group A rotavirus and bacterial agents associated with diarrhoea-induced hospitalisations in children below 5 years of age in Jammu.

    abstract::Out of 210 faecal samples collected from children below 5 years attending different hospitals in Jammu and exhibiting clinical signs of diarrhoea, 41.9% samples were found positive for group A rotavirus by RNA-PAGE. Escherichia coli isolated in the study belonged to nine serogroups, out of which O69 was most frequent,...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.124308

    authors: Gazal S,Taku A,Bhat MA,Badroo G

    更新日期:2014-01-01 00:00:00

  • The antibiotics of choice for the treatment of melioidosis in Indian set up.

    abstract::Therapeutic options for the treatment of melioidosis caused by Burkholderia pseudomallei are limited due to the inherent resistance conferred by this pathogen to various groups of antibiotics. Witnessing an increase in the number of microbiological culture-confirmed cases of melioidosis at our settings in the past few...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.188340

    authors: Shaw T,Tellapragada C,Eshwara VK,Bhat HV,Mukhopadhyay C

    更新日期:2016-07-01 00:00:00

  • Evaluation of a modified double-disc synergy test for detection of extended spectrum beta-lactamases in AMPC beta-lactamase-producing proteus mirabilis.

    abstract::The detection of extended-spectrum beta-lactamases (ESBLs) in gram-negative bacteria that produce AmpC beta-lactamases is problematic. In the present study, the performance of modified double-disc synergy test (MDDST) that employs a combination of cefepime and piperacillin-tazobactam for the detection of Proteus mirab...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.38860

    authors: Khan MK,Thukral SS,Gaind R

    更新日期:2008-01-01 00:00:00

  • Treatment of discarded blood units: disinfection with hypochlorite / formalin versus steam sterilization.

    abstract::Blood bank regulations and bio medical waste rules of India advocate disinfection of contaminated blood units. Incineration is not recommended due to poly-vinyl chloride (PVC) content of blood bags. This study was designed to evaluate the efficacy of chemical disinfection of blood units deliberately contaminated with ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Chitnis V,Chitnis S,Patil S,Chitnis D

    更新日期:2003-10-01 00:00:00

  • Changing trends of culture-positive typhoid fever and antimicrobial susceptibility in a tertiary care North Indian Hospital over the last decade.

    abstract:Purpose:The present study was undertaken to analyse the trend in prevalence of culture-positive typhoid fever during the last decade and to determine antimicrobial susceptibility profile of Salmonella Typhi and Salmonella Paratyphi A isolated from patients of enteric fever presenting to our hospital. Methods:All the c...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_17_412

    authors: Sharma P,Dahiya S,Manral N,Kumari B,Kumar S,Pandey S,Sood S,Das BK,Kapil A

    更新日期:2018-01-01 00:00:00

  • An analysis of underlying factors for seasonal variation in gonorrhoea in India: a 6-year statistical assessment.

    abstract:PURPOSE:A statistical assessment of a disease is often necessary before resources can be allocated to any control programme. No literature on seasonal trends of gonorrhoea is available from India. OBJECTIVES:The objectives were (1) to determine, if any, seasonal trends were present in India (2) to describe factors con...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.154853

    authors: Kakran M,Bala M,Singh V

    更新日期:2015-04-01 00:00:00

  • Distribution of Malassezia species in patients with pityriasis versicolor in Northern Iran.

    abstract:PURPOSE:Malassezia yeasts are globally distributed agents of pityriasis versicolor and are implicated in the pathogenesis of seborrhoeic and atopic dermatitis. The aim of this study is to identify the Malassezia species obtained from pityriasis versicolor patients, using morphological, biochemical, physiological as wel...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.55445

    authors: Shokohi T,Afshar P,Barzgar A

    更新日期:2009-10-01 00:00:00

  • Streptococcus dysgalactiae septic arthritis of sternoclavicular joint with bacteraemia.

    abstract::Invasive infections due to Streptococcus dysgalactiae are uncommon in the adult population, and sternoclavicular joint septic arthritis (SCSA) is usually caused by other organisms such as Staphylococcus aureus and Pseudomonas aeruginosa. We hereby report a case of SCSA caused by this organism. The patient responded we...

    journal_title:Indian journal of medical microbiology

    pub_type:

    doi:10.4103/ijmm.IJMM_20_257

    authors: Dhekane PN,Gopalakrishnan R,Sree VL,Devaprasad VD

    更新日期:2020-07-01 00:00:00

  • Injection site abscess due to Mycobacterium fortuitum: a case report.

    abstract::Injection abscess is an iatrogenic infection occurring as an isolated case or as cluster outbreak. These infections occur due to contaminated injectables or lapse in sterilisation protocol. While pathogens such as Pseudomonas, Klebsiella, E. coli, and S. aureus are the usual causative agents, unusual organisms such as...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Devi DR,Indumathi VA,Indira S,Babu PR,Sridharan D,Belwadi MR

    更新日期:2003-04-01 00:00:00

  • Antimicrobial susceptibility testing in India - a status survey.

    abstract::Resistance to a variety of antimicrobial agents is emerging in bacterial pathogens throughout the world. Since the accuracy of the antimicrobial susceptibility data is associated with the performance standard of the test, strict adherence to the standard procedures is essential. The Kirby-Bauer disc diffusion suscepti...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Sudha V,Prasad A,Khare S,Bhatia R

    更新日期:2001-10-01 00:00:00

  • Cutaneous infection with Mycobacterium fortuitum: an unusual presentation.

    abstract::Cutaneous infection with rapidly growing mycobacteria is uncommon and its diagnosis can be missed unless there is strong clinical suspicion coupled with microbiological confirmation. We report a case of localized recurrent soft tissue swelling of the foot by Mycobacterium fortuitum in a healthy adult male. The case is...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.43571

    authors: Sarma S,Thakur R

    更新日期:2008-10-01 00:00:00

  • Management of post-operative Nocardia endophthalmitis.

    abstract::Post-operative Nocardia endophthalmitis has an aggressive course and poor visual prognosis. It often masquerades as severe post-operative uveitis or toxic anterior segment syndrome due to the absence of vitreous involvement resulting in a delay in diagnosis. The poor prognosis in Nocardia endophthalmitis is due to sev...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.99506

    authors: Pradhan ZS,Jacob P,Korah S

    更新日期:2012-07-01 00:00:00

  • Learning from an outbreak: ESBL- the essential points.

    abstract::Extended spectrum beta-lactamase (ESBL) producing strains of Klebsiella pneumoniae have emerged as important nosocomial pathogens. The present report describes an outbreak of ESBL positive K. pneumoniae in a neonatal intensive care unit of a tertiary care center in southern India. The clinical and microbiological sign...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Shanmuganathan C,Ananthakrishnan A,Jayakeerthi SR,Kanungo R,Kumar A,Bhattacharya S,Badrinath S

    更新日期:2004-10-01 00:00:00

  • Refractory giardiasis: a molecular appraisal from a tertiary care centre in India.

    abstract:PURPOSE:The intestinal flagellate Giardia lamblia includes many genetically distinct assemblages, of which assemblage A and B, predominantly infect humans. Nitroimidazoles derivatives (metronidazole and tinidazole) and nitazoxanide are some of the therapeutic agents for treatment of giardiasis. Nevertheless, some indiv...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.142236

    authors: Yadav P,Tak V,Mirdha BR,Makharia GK

    更新日期:2014-10-01 00:00:00

  • Multidrug-resistant Enterobacteriaceae including metallo-β-lactamase producers are predominant pathogens of healthcare-associated infections in an Indian teaching hospital.

    abstract:PURPOSE:A study was carried out in an Indian teaching hospital in 2009 to detect the rate of surgical site infections (SSI) and peripheral vascular access site infections. MATERIALS AND METHODS:The study was a point-prevalence study involving over 300 patients. The presence of infection was determined according to the...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.76519

    authors: Sarma JB,Bhattacharya PK,Kalita D,Rajbangshi M

    更新日期:2011-01-01 00:00:00

  • Use of bactec 460 TB system in the diagnosis of tuberculosis.

    abstract:PURPOSE:To evaluate, the efficacy of BACTEC 460 TB system for the diagnosis of tuberculosis in a tertiary care hospital in Mumbai, India. METHODS:We compared 12,726 clinical specimens using BACTEC 460 TB system and conventional method for detection of Mycobacterium tuberculosis over a period of six years. RESULT:The ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.31059

    authors: Rodrigues CS,Shenai SV,Almeida D,Sadani MA,Goyal N,Vadher C,Mehta AP

    更新日期:2007-01-01 00:00:00

  • Effect of Azadirachta indica (neem) on the growth pattern of dermatophytes.

    abstract:PURPOSE:To determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) for the extracts of the leaves and seeds of the plant Azadirachta indica against various dermatophytes. METHODS:Clinical isolates of dermatophytes(Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Natarajan V,Venugopal PV,Menon T

    更新日期:2003-04-01 00:00:00

  • Severe acute respiratory syndrome.

    abstract::Severe acute respiratory syndrome (SARS) is a form of atypical pneumonia that apparently originated in Guangdong Province of the People's Republic of China in late 2002. This first came to the world's attention in late February 2003, and has since spread worldwide. As of June 23rd 2003, the disease had been reported f...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Thomas PA

    更新日期:2003-07-01 00:00:00

  • National survey of infection control programmes in South Asian association for Regional Cooperation countries in the era of patient safety.

    abstract:Background:The implementation of hospital infection prevention and control (IPC) in south Asia is not well described. We aimed to assess IPC programmes in hospitals in this region and explore opportunities for improvement. Methods:Attendees from hospitals in the South Asian Association for Regional Cooperation (SAARC)...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_18_82

    authors: Gupta SK,Siddharth V,Belagere MR,Stewardson AJ,Kant S,Singh S,Singh N

    更新日期:2018-10-01 00:00:00

  • Emergence of influenza A (H1N1) PDM09 in the remote Islands of India--a molecular approach.

    abstract:BACKGROUND:A disease outbreak of A (H1N1) PDM09 was reported in Andaman and Nicobar islands in 2009 with an attack rate of 33.5% among settler population and 26.3% among the aboriginal Nicobarese tribe. During the ongoing outbreak of A (H1N1) PDM09 disease in different parts of the world, a subject working in Dubai cit...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.148417

    authors: Muruganandam N,Bhattacharya D,Chaaithanya IK,Bhattacharya H,Reesu R,Maile A,Bharathi GS,Sugunan AP,Vijayachari P

    更新日期:2015-01-01 00:00:00

  • Cutaneous cryptococcosis among HIV infected patients.

    abstract::Five patients with HIV associated cutaneous cryptococcal infection are reported. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Vasanthi S,Padmavathy BK,Gopal R,Sundaram RS,Manoharan G

    更新日期:2002-07-01 00:00:00

  • Ophthalmomyiasis: three cases from North India.

    abstract::Three cases of external ophthalmomyiasis are reported here. The larvae were identified to be Oestrus ovis in two cases and Cochliomyia hominivorax in one. Two of the patients were immunocompetent while one was undergoing treatment for squamous cell carcinoma of eyelid. In the latter myiasis led to complete destruction...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.66490

    authors: Khurana S,Biswal M,Bhatti HS,Pandav SS,Gupta A,Chatterjee SS,Lyngdoh WV,Malla N

    更新日期:2010-07-01 00:00:00

  • Geographically distinct North-East Indian Helicobacter pylori strains are highly sensitive to clarithromycin but are levofloxacin resistant.

    abstract:Purpose:Helicobacter pylori causes various gastro-intestinal diseases. Antibiotic resistance to commonly used antibiotics for the treatment of H. pylori infection is the major cause for treatment failure. The aim of this study is to determine the antimicrobial susceptibility pattern for clarithromycin and levofloxacin ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_19_158

    authors: Mahant S,Sharma AK,Gehlot V,Mukhopadhyay AK,Chhawchharia A,Dutta S,Agarwal A,Som A,Das K,Das R

    更新日期:2019-07-01 00:00:00

  • Occurrence of II and V staphylococcal cassette chromosome mec types among coagulase-negative staphylococci from Northeastern part of India.

    abstract:Introduction:Coagulase Negative Staphylococci, the most commonly isolated pathogen are becoming emerging threats to the community as well as to the nosocomial environment. The present study underscores the distribution of Staphylococcal cassette chromosome mec (SCCmec) types among Methicillin resistant Coagulase Negati...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_18_285

    authors: Bhowmik D,Chakraborty P,Bhowmick R,Sarkar R,Chetri S,Bhattacharjee A

    更新日期:2018-10-01 00:00:00

  • Characterisation of antimicrobial resistance in Salmonellae during 2014-2015 from four centres across India: An ICMR antimicrobial resistance surveillance network report.

    abstract:PURPOSE:The main purpose of this study was to establish 'Antimicrobial Resistance Surveillance Network' in India and to monitor the antimicrobial susceptibility profile of clinical isolates to establish a national network across the country for monitoring antimicrobial resistance in Salmonella. MATERIALS AND METHODS:T...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,多中心研究

    doi:10.4103/ijmm.IJMM_16_382

    authors: Dahiya S,Sharma P,Kumari B,Pandey S,Malik R,Manral N,Veeraraghavan B,Pragasam AK,Ray P,Gautam V,Sistla S,Parija SC,Walia K,Ohri V,Das BK,Sood S,Kapil A

    更新日期:2017-01-01 00:00:00