Abstract：
:Bacterial infections of the eye are common and ophthalmologists are spoilt for choice with a variety of antibiotics available in the market. Antibiotics can be administered in the eye by a number of routes; topical, subconjunctival, subtenon and intraocular. Apart from a gamut of eye drops available, ophthalmologists also have the option of preparing fortified eye drops from parenteral formulations, thereby, achieving high concentrations; often much above the minimum inhibitory concentration (MIC), of antibiotics in ocular tissues during therapy. Antibiotic resistance among ocular pathogens is increasing in parallel with the increase seen over the years in bacteria associated with systemic infections. Although it is believed that the rise in resistant ocular bacterial isolates is linked to the rise in resistant systemic pathogens, recent evidence has correlated the emergence of resistant bacteria in the eye to prior topical antibiotic therapy. One would like to believe that either of these contributes to the emergence of resistance to antibiotics among ocular pathogens. Until recently, ocular pathogens resistant to fluoroquinolones have been minimal but the pattern is currently alarming. The new 8-fluoroquinolone on the scene-besifloxacin, is developed exclusively for ophthalmic use and it is hoped that it will escape the selective pressure for resistance because of lack of systemic use. In addition to development of new antibacterial agents, the strategies to halt or control further development of resistant ocular pathogens should always include judicious use of antibiotics in the treatment of human, animal or plant diseases.
journal_name
Indian J Med Microbioljournal_title
Indian journal of medical microbiologyauthors
Sharma Sdoi
10.4103/0255-0857.83903subject
Has Abstractpub_date
2011-07-01 00:00:00pages
218-22issue
3eissn
0255-0857issn
1998-3646pii
IndianJMedMicrobiol_2011_29_3_218_83903journal_volume
29pub_type
杂志文章,评审abstract：:We receive around 60 cases of hepatic abscess in a year. The commonest diagnosis reached at the time of discharge is amoebic liver abscess. The diagnosis of amoebic liver abscess is mostly presumptive and thus the patients are usually given a mixed treatment with injection ceftriaxone and tablet metronidazole. Here we...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.158576
更新日期：2015-07-01 00:00:00
abstract：:Three cases of external ophthalmomyiasis are reported here. The larvae were identified to be Oestrus ovis in two cases and Cochliomyia hominivorax in one. Two of the patients were immunocompetent while one was undergoing treatment for squamous cell carcinoma of eyelid. In the latter myiasis led to complete destruction...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.66490
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Detecting plasmid-mediated AmpC (pAmpC) β-lactamase-producing organism is important for optimal infection control and providing accurate and effective treatment option for physicians. OBJECTIVES:The aim of this study was to investigate the prevalence of pAmpC β-lactamase and compare the results of boronic a...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.108723
更新日期：2013-01-01 00:00:00
abstract：:Post-operative Nocardia endophthalmitis has an aggressive course and poor visual prognosis. It often masquerades as severe post-operative uveitis or toxic anterior segment syndrome due to the absence of vitreous involvement resulting in a delay in diagnosis. The poor prognosis in Nocardia endophthalmitis is due to sev...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.99506
更新日期：2012-07-01 00:00:00
abstract：:Researchers are expanding the applications of nanotechnology in the field of medicine since mid-2000. These technologies include nanoarrays, protein arrays, nanopore technology, nanoparticles as a contrivance in immunoassays and nanosensors, among others. Nanobiotechnologies are clinically applicable and possess the p...
journal_title：Indian journal of medical microbiology
pub_type： 社论,评审
doi：
更新日期：2008-10-01 00:00:00
abstract：Introduction:Non-tuberculous mycobacteria, although identified as pathogenic to humans long time ago, are emerging as the new threat in the past two decades. Even in tuberculosis endemic country such as India, they are being isolated from the clinical specimens more often than previously. This change in trend is of con...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_20_274
更新日期：2020-04-01 00:00:00
abstract：Background:The implementation of hospital infection prevention and control (IPC) in south Asia is not well described. We aimed to assess IPC programmes in hospitals in this region and explore opportunities for improvement. Methods:Attendees from hospitals in the South Asian Association for Regional Cooperation (SAARC)...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_18_82
更新日期：2018-10-01 00:00:00
abstract：:Treatment of extended spectrum beta-lactamase (ESBL) producing strains of Enterobacteriaceae has emerged as a major challenge in hospitalised as well as community based patients. Infections due to ESBL producers range from uncomplicated urinary tract infection to life threatening sepsis. Although several reviews have ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章,评审
doi：10.4103/0255-0857.19889
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Hepatitis C is global health problem affecting a significant portion of the world's population. Available data in Western Maharashtra on seroprevalence, risk factors and genotype distribution are very limited. OBJECTIVES:The present study was carried out to estimate the seroprevalence, factor...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_16_96
更新日期：2017-10-01 00:00:00
abstract：:Blood bank regulations and bio medical waste rules of India advocate disinfection of contaminated blood units. Incineration is not recommended due to poly-vinyl chloride (PVC) content of blood bags. This study was designed to evaluate the efficacy of chemical disinfection of blood units deliberately contaminated with ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：:Serum samples from 465 subjects aged between 1 and 25 years were tested for antibody against hepatitis A virus (HAV) [anti-HAV IgG and IgM] to determine the seroprevalence of HAV antibody and do a cost-benefit analysis for decision making about vaccination against HAV among the general population of Bangladesh. A high...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:We evaluated the incidence and risk factors of Staphylococcus aureus colonisation in 300 treatment-naïve HIV patients. Swabs from anterior nares and pharynx were cultured. Eighty-eight patients (29.3%) were colonised with S. aureus (47.7% nasal, 23.8% pharyngeal and 28.5% at both sites), which yielded 112 isolates. Me...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_20_5
更新日期：2020-07-01 00:00:00
abstract：:We report here the emergence of a new focus of cutaneous leishmaniasis (CL) due to Leishmania tropica (L. tropica) in the Ajmer city of Rajasthan, India, a previously non-endemic area. Between January-February 2006, 13 new indigenously acquired cases of CL were diagnosed among the patients attending the Skin and STD d...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.34774
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:The chances of health care waste (Biomedical waste) coming in contact with the health care workers, patients, visitors, sanitary workers, waste handlers, public, rag pickers and animals during transportation are high. MATERIALS AND METHODS:The study was conducted over a period of seven months (April 2013-...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.158559
更新日期：2015-07-01 00:00:00
abstract：:Mycobacterial diseases continue to cause high morbidity and mortality. Isolation, identification and sensitivity testing form the backbone of laboratory investigations. M. tuberculosis isolation needs 6-8 weeks on conventional egg containing media. For rapid isolation various methods have been evaluated. We evaluated ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.16050
更新日期：2005-04-01 00:00:00
abstract：:The surveillance in Chennai identified 134 children and 443 adults clinically suspected for leptospirosis. Of these, 35 (26.1%) children and 118 (26.6%) adults had laboratory confirmed diagnosis for leptospirosis. The paediatric leptospirosis exhibited a higher frequency of classic features of Weil's disease. The prev...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.180353
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Culture filtrate proteins (CFPs) of Mycobacterium tuberculosis are potential vaccine candidates. OBJECTIVE:The aim was to study the influence of iron levels on CFPs and assess the immuno-protective potential of defined antigenic fractions from high (8 μg Fe/mL) and low iron (0.02 μg Fe / mL) cultures of M. ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.99495
更新日期：2012-07-01 00:00:00
abstract：PURPOSE:To evaluate, the efficacy of BACTEC 460 TB system for the diagnosis of tuberculosis in a tertiary care hospital in Mumbai, India. METHODS:We compared 12,726 clinical specimens using BACTEC 460 TB system and conventional method for detection of Mycobacterium tuberculosis over a period of six years. RESULT:The ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.31059
更新日期：2007-01-01 00:00:00
abstract：:Great advances in technology produce unique challenges. Every technology also has a dual use, which needs to be understood and managed to extract maximum benefits for mankind and the development of civilization. The achievements of physicists in the mid-20th century resulted in the nuclear technology, which gave us th...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章,评审
doi：10.4103/0255-0857.90155
更新日期：2011-10-01 00:00:00
abstract：:Chlamydia trachomatis is currently recognized as one of the most common sexually transmitted pathogen and a major cause of perinatally acquired infection. Vertical transmission of infection from mother to the infant may result in the development of conjunctivitis and pneumonia. The study was conducted with the aim of ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:Microbiological contamination of blood and blood products is a well-recognised transfusion risk. This study was performed in the blood bank of our oncology centre, with an objective to detect bacterial contamination in our blood products using oxygen consumption as a surrogate marker [Pall Enhanced Bacterial Detection...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.96695
更新日期：2012-04-01 00:00:00
abstract：:Hemophagocytic lymphohistiocytosis (HLH) triggered by Parvovirus B19 and Epstein-Barr virus co-infection is rare and unknown in infants. A 2-month-old male infant with fever, rash, bicytopenia and hepato-splenomegaly died owing to diagnostic dilemmas. Hence simply testing for hyperferritinaemia and hypertriglyceridemi...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.129819
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:Mycobacterial antigen MPB64 is a secretory protein specific for Mycobacterium tuberculosis complex. A lateral flow immunochromatographic assay (ICA) is a method used for the rapid differentiation of M. tuberculosis complex. AIM:We aimed to evaluate the performance of ICA in rapid differentiation of M. tuber...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.71817
更新日期：2010-10-01 00:00:00
abstract：:Extended spectrum -lactamases (ESBLs) are plasmid mediated, TEM and SHV derived enzymes, first isolated in Western Europe in mid 1980s, most commonly in Klebsiella spp., followed by Escherichia coli. These enzymes are capable of hydrolyzing broad spectrum cephalosporins and monobactams but inactive against cephamycins...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：:Invasive candidiasis is a life-threatening complication of critically ill immunocompromised patients with high attributable mortality. Due to non-specific clinical presentation, early detection of candidemia and accurate identification of Candida species are essential pre-requisites for improved therapeutic outcome. S...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章,评审
doi：10.4103/0255-0857.99482
更新日期：2012-07-01 00:00:00
abstract：PURPOSE:To report a fatal case of disseminated trichosporonosis caused by Trichosporon asahii in a patient with acute myeloblastic leukemia (AML) and to present an update on systemic trichosporonosis with special reference to India. METHODS:The diagnosis was based on repeated demonstration of budding yeast cells and a...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Paragonimiasis is a foodborne parasitic zoonosis caused by lung fluke species of the genus Paragonimus. The Paragonimus westermani is the most common human pathogen in Asian countries. In northeast India, Paragonimus heterotremus has been documented as the only human pathogen in the earlier literature. In India, P. we...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.150950
更新日期：2015-02-01 00:00:00
abstract：:Tuberculosis accounts for up to 4% of acute pericarditis and 7% cases of cardiac tamponade. Prompt treatment can be life saving but requires accurate diagnosis. We report a case of 30-year-old male who presented with fever, chills, and dry nonproductive cough since one month. The case was diagnosed by radiological fin...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：Background:The WHO Multimodal Hand Hygiene Improvement Strategy (MHHIS) has been proposed to improve the Hand Hygiene (HH) compliance of the WHO recommendations on HH.Therefore, the current study was planned in our neonatal unit with the objective of evaluating the effectiveness of a Hand Hygiene Promotional Program (H...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_20_47
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:The purpose of our study was to compare various laboratory diagnostic methods, namely histopathological examination, Ziehl-Neelsen (ZN) stain, AFB culture by conventional Lowenstein-Jensen (LJ) method and fluorescence-based mycobacterial growth indicator tube (MGIT) technique and polymerase chain reaction (PC...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.90173
更新日期：2011-10-01 00:00:00
