Simvastatin combined with antioxidant attenuates the cerebral vascular endothelial inflammatory response in a rat traumatic brain injury.

abstract：:Introduction. Pelvic organ prolapse (POP) and urinary incontinence (UI) have increasing prevalence in the elderly population. The aim of this study was to compare the comorbidities of these procedures between <70 y/o and ≥70 y/o patients. Materials and Methods. In our retrospective study over a period of 2.5 years, 40...

journal_title：BioMed research international

authors： Joukhadar R,Wöckel A,Herr D,Paulus V,Radosa J,Hamza A,Solomayer E,Baum S

更新日期：2016-01-01 00:00:00

abstract：:Study of the probiotic potential of microorganisms isolated from fermented foods has been increasing, especially studies related to lactobacilli. In intestinal models, lactobacilli have demonstrated beneficial properties, such as anti-inflammatory activity and increased antibody production, but the molecular mechanism...

journal_title：BioMed research international

authors： Pessoa WFB,Melgaço ACC,de Almeida ME,Ramos LP,Rezende RP,Romano CC

更新日期：2017-01-01 00:00:00

abstract：:Small renal masses have been diagnosed increasingly in recent decades, allowing surgical treatment by partial nephrectomy. This treatment option is associated with better renal function preservation, in comparison with radical nephrectomy. However, for obtaining a bloodless field during surgery, occlusion of renal art...

journal_title：BioMed research international

authors： Buys-Gonçalves GF,Abreu LAS,Gregorio BM,Sampaio FJB,Pereira-Sampaio MA,de Souza DB

更新日期：2019-02-07 00:00:00

abstract：:The presence of acquired mutations within the JAK2, CALR, and MPL genes in the majority of patients with myeloproliferative neoplasms (MPN) affords the opportunity to utilise these mutations as markers of minimal residual disease (MRD). Reduction of the mutated allele burden has been reported in response to a number o...

journal_title：BioMed research international

authors： Haslam K,Langabeer SE

更新日期：2016-01-01 00:00:00

abstract：Objectives:To evaluate the effects of pentobarbital dosages on lower urinary tract function and to define an appropriate dosage of sodium pentobarbital that would be suitable for urodynamic studies in which recovery from anesthesia and long term survive were needed for subsequent experiment. Methods:Twenty-four 8-week...

journal_title：BioMed research international

authors： Xu SF,Du GH,Abulikim K,Cao P,Tan HB

更新日期：2020-06-11 00:00:00

abstract：:The polyherbal formulation containing Allium sativum L., Terminalia bellirica (Gaertn.) Roxb., Curcuma aeruginosa Roxb., and Amomum compactum Sol ex. Maton has been used for hypertension treatment empirically. Our previous study showed its blood pressure-lowering effect on a rat model of hypertension. However, toxicit...

journal_title：BioMed research international

authors： Sholikhah EN,Mustofa M,Nugrahaningsih DAA,Yuliani FS,Purwono S,Sugiyono S,Widyarini S,Ngatidjan N,Jumina J,Santosa D,Koketsu M

更新日期：2020-03-24 00:00:00

abstract：:The AT-hook transcription factor, AKNA, is a nuclear protein that affects a few physiological and pathological processes including cancer. Here, we investigated the role of AKNA in gastric cancer (GC). By using quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot assays, AKNA was found deregulat...

journal_title：BioMed research international

authors： Wang G,Sun D,Li W,Xin Y

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:Prelacteal feed (feeding any other substance before first breastfeeding) appears to be common despite its harmful effects. By definition a child provided with prelacteal feed (PLF) is not exclusively breastfed and PLF has many implications for the success and early initiation of breastfeeding. Objectives. To...

journal_title：BioMed research international

authors： El-Gilany AH,Abdel-Hady DM

更新日期：2014-01-01 00:00:00

abstract：:Mitochondrial heat shock proteins, such as HSP60, are chaperones responsible for the folding, transport, and quality control of mitochondrial matrix proteins and are essential for maintaining life. Both prosurvival and proapoptotic roles have been proposed for HSP60, and HSP60 is reportedly involved in the initiation ...

journal_title：BioMed research international

authors： Chen TH,Liu SW,Chen MR,Cho KH,Chen TY,Chu PH,Kao YY,Hsu CH,Lin KM

更新日期：2015-01-01 00:00:00

abstract：:Bayesian analysis was used to estimate the pig's and herd's true prevalence of enteropathogenic Yersinia in serum samples collected from Finnish pig farms. The sensitivity and specificity of the diagnostic test were also estimated for the commercially available ELISA which is used for antibody detection against entero...

journal_title：BioMed research international

authors： Vilar MJ,Ranta J,Virtanen S,Korkeala H

更新日期：2015-01-01 00:00:00

abstract：:Patients with clinical suspicion of large-vessel vasculitis (LVV) may present with nonspecific signs and symptoms and increased inflammatory parameters and may remain without diagnosis after routine diagnostic procedures. Both the nonspecificity of the radiopharmaceutical (18)F-FDG and the synergy of integrating funct...

journal_title：BioMed research international

authors： Balink H,Bennink RJ,van Eck-Smit BL,Verberne HJ

更新日期：2014-01-01 00:00:00

abstract：:Elevated levels of resistin and epidermal growth factor receptor (EGFR) facilitate the development of breast cancer, although there are no reports of any correlation between these proteins. This study analyzed 392 human breast cancer tissue specimens and 42 samples of adjacent normal tissue. Rates of positive and stro...

journal_title：BioMed research international

authors： Zeng Y,Tang CH,Wang Y,Lu HJ,Huang BF,Wang Q,Shao JK,Jin LL,Wang CQ,Teng LS

更新日期：2020-11-28 00:00:00

abstract：:Emergence and spread of pandemic strains of Vibrio parahaemolyticus have drawn attention to make detailed study on their genomes. The pathogenicity of V. parahaemolyticus has been associated with thermostable-direct hemolysin (TDH) and/or TDH-related hemolysin (TRH). The present study evaluated characteristics of tdh ...

journal_title：BioMed research international

authors： Bhowmik SK,Pazhani GP,Ramamurthy T

更新日期：2014-01-01 00:00:00

abstract：:ELABELA (ELA) is considered to be implicated in the pathophysiology of preeclampsia (PE), since ELA-deficient mice exhibited PE-like symptoms and infusion of exogenous ELA normalized the gestational hypertension (GH) and proteinuria. However, no evidence show that circulating ELA is deficient in early placental develo...

journal_title：BioMed research international

authors： Ma S,Guo C,Zhang J,Long S,Tan H,You Y

更新日期：2020-09-28 00:00:00

abstract：:Removal of MTA from dentin by applying 37% hydrochloric acid (HCl) to reduce microhardness and push-out bond strength. Forty dentin slices were filled with WMTA and divided into two groups (n = 20). Ten slices remained untreated while others were exposed to either HCl or phosphate buffer saline (PBS) and all samples w...

journal_title：BioMed research international

authors： Saghiri MA,Garcia-Godoy F,Gutmann JL,Sheibani N,Asatourian A,Lotfi M,Elyasi M

更新日期：2013-01-01 00:00:00

abstract：:Among other diseases characterized by the onset of cachexia, congestive heart failure takes a place of relevance, considering the high prevalence of this pathology in most European countries and in the United States, and is undergoing a rapid increase in developing countries. Actually, only few models of cardiac cache...

journal_title：BioMed research international

authors： Sala V,Gatti S,Gallo S,Medico E,Cantarella D,Cimino J,Ponzetto A,Crepaldi T

更新日期：2016-01-01 00:00:00

abstract：:Densitometry data generated for Western blots are commonly used to compare protein abundance between samples. In the last decade, it has become apparent that assumptions underpinning these comparisons are often violated in studies reporting Western blot data in the literature. These violations can lead to erroneous in...

journal_title：BioMed research international

authors： Butler TAJ,Paul JW,Chan EC,Smith R,Tolosa JM

更新日期：2019-01-21 00:00:00

abstract：:The chromosomal changes accompanying bivalve evolution are an area about which few reports have been published. To improve our understanding on chromosome evolution in Veneridae, ribosomal RNA gene clusters were mapped by fluorescent in situ hybridization (FISH) to chromosomes of five species of venerid clams (Venerup...

journal_title：BioMed research international

authors： Pérez-García C,Hurtado NS,Morán P,Pasantes JJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Macrosomia has become a worldwide problem with the rapid economic growth in the past few years. However, the detailed mechanism of how the macrosomia happened remains unknown. Growing evidence indicates that miRNAs are involved in maintaining metabolic homeostasis. We hypothesized that serum miRNAs are poten...

journal_title：BioMed research international

authors： Hu L,Han J,Zheng F,Ma H,Chen J,Jiang Y,Jiang H

更新日期：2014-01-01 00:00:00

abstract：:The role of nitric oxide and its reactive derivatives (NO x ) is well known in the pathogenesis of multiple sclerosis, which is an inflammatory disease while NO x seems to be important in coordinating inflammatory response. The...

journal_title：BioMed research international

authors： Niedziela N,Adamczyk-Sowa M,Niedziela JT,Mazur B,Kluczewska E,Sowa P,Gąsior M

更新日期：2016-01-01 00:00:00

abstract：:Engineering three-dimensional (3D) vascularized constructs remains a challenge due to the inability to form rich microvessel networks. In this study we engineered a prevascularized 3D cell sheet construct for tissue regeneration using human bone marrow-derived mesenchymal stem cells (hMSCs) and human umbilical vein en...

journal_title：BioMed research international

authors： Ren L,Ma D,Liu B,Li J,Chen J,Yang D,Gao P

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The PiCCO transpulmonary thermodilution technique provides two indices of cardiac systolic function, the cardiac function index (CFI) and the global ejection fraction (GEF). Both appear to be correlated with left ventricular ejection fraction (LVEF) measured by echocardiography in patients with circulatory...

journal_title：BioMed research international

authors： Perny J,Kimmoun A,Perez P,Levy B

更新日期：2014-01-01 00:00:00

abstract：:Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic data, biological pathw...

journal_title：BioMed research international

authors： Chen X,Wang Y,Wang P,Lian B,Li C,Wang J,Li X,Jiang W

更新日期：2015-01-01 00:00:00

abstract：:Long noncoding RNAs play an essential role in bladder cancer progression. The role of long noncoding RNA EGFR-AS1 in bladder cancer needs further study. We used clinical specimens to analyze the relationship between EGFR-AS1 and bladder cancer patients' characteristics. The functional experiments and mechanism studies...

journal_title：BioMed research international

authors： Wang A,Jiang A,Gan X,Wang Z,Huang J,Dong K,Liu B,Wang L,Chen M

更新日期：2020-12-22 00:00:00

abstract：INTRODUCTION:Inflammation in dental pulp cells (DPCs) initiated by Lipopolysaccharide (LPS) results in dental pulp necrosis. So far, whether there is a common system regulating inflammation response and tissue regeneration remains unknown. miR-146a is closely related to inflammation. Basic fibroblast growth factor (bFG...

journal_title：BioMed research international

authors： Liu L,Shu S,Cheung GS,Wei X

更新日期：2016-01-01 00:00:00

abstract：:Ayurvedic and traditional medical practitioners of Sri Lanka use the decoction of the immature inflorescence of Cocos nucifera L. (IC) variety aurantiaca for the treatment of menorrhagia. The progestogenic effect of the ethyl acetate soluble proanthocyanidins (EASPA) of the IC in female rats at a dose of 3.5 mg/kg bod...

journal_title：BioMed research international

authors： Ekanayake CP,Thammitiyagodage MG,Padumadasa S,Seneviratne B,Padumadasa C,Abeysekera AM

更新日期：2019-12-03 00:00:00

abstract：:Human epididymis protein 4 (HE4) is an available tumor biomarker mainly for detecting ovarian cancer. However, it is unknown whether it can be a novel indicator for diagnosis of diabetic kidney disease (DKD). The aim of this study was to investigate the possibility of serum HE4 as a novel biomarker for DKD in patients...

journal_title：BioMed research international

authors： Zhang M,Zhao B,Xie J,Liang Y,Yang Z

更新日期：2019-11-11 00:00:00

abstract：Objective:The exact shape of the dose-response relationship between maternal body mass index (BMI) and the risk of congenital heart defects (CHDs) in infants has not been clearly defined yet. This study aims to further clarify the relationship between maternal obesity and the risk of CHDs in infants by an overall and d...

journal_title：BioMed research international

authors： Liu X,Ding G,Yang W,Feng X,Li Y,Liu H,Zhang Q,Ji L,Li D

更新日期：2019-07-07 00:00:00

abstract：:This study attempted to find novel age-related macular degeneration (AMD) related genes based on 36 known AMD genes. The well-known shortest path algorithm, Dijkstra's algorithm, was applied to find the shortest path connecting each pair of known AMD related genes in protein-protein interaction (PPI) network. The gene...

journal_title：BioMed research international

authors： Zhang J,Jiang M,Yuan F,Feng KY,Cai YD,Xu X,Chen L

更新日期：2013-01-01 00:00:00

abstract：:Background. Central systolic blood pressure (CSBP) has prognostic significance and simplified devices for its estimation have been introduced recently. The aim of this study was to assess the achievement of the target CSBP in treated hypertensive patients. Subjects and Methods. One hundred patients with well-controlle...

journal_title：BioMed research international

authors： Bulas J,Potočárová M,Murín J,Kozlíková K,Luha J,Čaprnda M

更新日期：2017-01-01 00:00:00