AKNA Is a Potential Prognostic Biomarker in Gastric Cancer and Function as a Tumor Suppressor by Modulating EMT-Related Pathways.

abstract：:The differential effects of a selective kappa- (κ-) opioid receptor agonist, U50488, were elucidated by monitoring the contraction of isolated guinea pig atrial and ventricular muscles. In electrically driven left atria, U50488 in nanomolar concentration range decreased the contractile force. Norbinaltorphimine (norBN...

journal_title：BioMed research international

authors： Hung CF,Li HJ,Chang HH,Lee GA,Su MJ

更新日期：2015-01-01 00:00:00

abstract：:Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate resources, sociocultural barriers, and sampling issues impede their success in low-income countries. To overcome these issues, this study aimed to evaluate the performance of human papillomavirus (HPV) testing from dried ur...

journal_title：BioMed research international

authors： Frati ER,Martinelli M,Fasoli E,Colzani D,Bianchi S,Binda S,Olivani P,Tanzi E

更新日期：2015-01-01 00:00:00

abstract：:Aim. To investigate the expression of miR-940 in the hepatocellular carcinoma (HCC) and its impact on function and biological mechanism in the HCC cells. Methods. Quantitative RT-PCR analysis was used to quantify miR-940 expression in 46 cases of tissues and cells. Transfection of HCC cell lines was performed by miR-9...

journal_title：BioMed research international

authors： Ding D,Zhang Y,Yang R,Wang X,Ji G,Huo L,Shao Z,Li X

更新日期：2016-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/7268308.]. ...

journal_title：BioMed research international

authors： Lin JA,Blanco R,Shibata Y,Nakamoto T,Lin KH

更新日期：2018-07-05 00:00:00

abstract：:The aims of the present research are to investigate the possible predictors of pancreatic cancer, in particular smoking status, alcohol consumption, hypercholesterolemia, and diabetes mellitus, in patients with histologically confirmed pancreatic carcinoma and to examine the synergism between risk factors. A case-cont...

journal_title：BioMed research international

authors： La Torre G,Sferrazza A,Gualano MR,de Waure C,Clemente G,De Rose AM,Nicolotti N,Nuzzo G,Siliquini R,Boccia A,Ricciardi W

更新日期：2014-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disorder of the synovial membrane that results in the destruction of bone and cartilage in affected joints. Tocilizumab is a biological agent and an anti-interleukin-6 (IL-6) receptor monoclonal antibody that blocks IL-6-mediated inflammatory processes in RA patients...

journal_title：BioMed research international

authors： Yanagida M,Kawasaki M,Fujishiro M,Miura M,Ikeda K,Nozawa K,Kaneko H,Morimoto S,Takasaki Y,Ogawa H,Takamori K,Sekigawa I

更新日期：2013-01-01 00:00:00

abstract：:Synthetic lethality (SL) is a novel strategy for anticancer therapies, whereby mutations of two genes will kill a cell but mutation of a single gene will not. Therefore, a cancer-specific mutation combined with a drug-induced mutation, if they have SL interactions, will selectively kill cancer cells. While numerous SL...

journal_title：BioMed research international

authors： Li XJ,Mishra SK,Wu M,Zhang F,Zheng J

更新日期：2014-01-01 00:00:00

abstract：:Paclitaxel, a class of taxane with microtubule stabilising ability, has remained with platinum based therapy, the standard care for primary ovarian cancer management. A deeper understanding of the immunological basis and other potential mechanisms of action together with new dosing schedules and/or routes of administr...

journal_title：BioMed research international

authors： Kampan NC,Madondo MT,McNally OM,Quinn M,Plebanski M

更新日期：2015-01-01 00:00:00

abstract：OBJECT:Video-assisted thoracoscopic sympathectomy is a safe, effective, and minimally invasive procedure for primary hyperhidrosis. This study aims to evaluate long-term results and patients' quality of life and investigate potential variables responsible for compensatory sweating after one-stage bilateral single-port ...

journal_title：BioMed research international

authors： Ibrahim M,Menna C,Andreetti C,Ciccone AM,D'Andrilli A,Maurizi G,Pomes LM,Cassiano F,Venuta F,Rendina EA

更新日期：2013-01-01 00:00:00

abstract：:Although studies have shown that human migration is one of the risk factors for the spread of drug-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA), surveillance studies examining MRSA among refugee populations in the US are lacking. This study aimed to assess the prevalence and molecular...

journal_title：BioMed research international

authors： Kadariya J,Thapaliya D,Bhatta S,Mahatara RL,Bempah S,Dhakal N,Smith TC

更新日期：2019-07-01 00:00:00

abstract：:Influenza virus contains two highly variable envelope glycoproteins, hemagglutinin (HA) and neuraminidase (NA). Here we show that, while HA evolution is much more complex than NA evolution, it still shows abrupt punctuation changes linked to punctuation changes of NA. HA exhibits proteinquakes, which resemble earthqua...

journal_title：BioMed research international

authors： Phillips JC

更新日期：2015-01-01 00:00:00

abstract：:The objective of this study was the synthesis of folic acid- (FA-) targeted polymeric micelles of Synperonic PE/F 127-cholesteryl hemisuccinate (PF127-Chol) for specific delivery of docetaxel (DTX). Targeted or nontargeted micelles loaded with DTX were prepared via dialysis method. The effects of processing variables ...

journal_title：BioMed research international

authors： Varshosaz J,Taymouri S,Hassanzadeh F,Javanmard SH,Rostami M

更新日期：2015-01-01 00:00:00

abstract：:Multiparametric MRI of the prostate combines high-resolution anatomic imaging with functional imaging of alterations in normal tissue caused by neoplastic transformation for the identification and characterization of in situ prostate cancer. Lesion detection relies on a systematic approach to the analysis of both anat...

journal_title：BioMed research international

authors： Margolis DJ

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:The aims of this study were first to clearly define two different entities: locoregional recurrences and limited metastatic disease and secondly to evaluate the place of extensive surgery in these two types of recurrence. MATERIAL AND METHODS:Twenty-four patients were followed from June 2004 until May 2014....

journal_title：BioMed research international

authors： Berlière M,Duhoux FP,Taburiaux L,Lacroix V,Galant C,Leconte I,Fellah L,Lecouvet F,Bouziane D,Piette P,Lengele B

更新日期：2015-01-01 00:00:00

abstract：Purpose:The aim of this study is to evaluate the effectiveness of laboratory serum tests in the diagnosis of infected nonunion. Methods:Forty-two patients suspected of having infected nonunion were investigated in the study. The serum levels of white blood-cell count (WBC), C-reactive protein (CRP), erythrocyte sedime...

journal_title：BioMed research international

authors： Wang S,Yin P,Quan C,Khan K,Wang G,Wang L,Cui L,Zhang L,Zhang L,Tang P

更新日期：2017-01-01 00:00:00

abstract：:Aims. To compare the clinical features of endometrial polyps (EPs) between patients with endometriosis (EM) (EM group) and without EM (non-EM group). Methods and Results. Seventy-six cases in the EM group and 133 cases in the non-EM group underwent laparotomy or hysteroscopy and laparoscopy; later, it was confirmed th...

journal_title：BioMed research international

authors： Wang N,Zhang Y,Liu B

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:This paper presents the final results of a cross-sectional study started in 2010. It compares the perceived efficacy of different types of tobacco health warning (texts versus shocking pictures) to quit or reduce tobacco use. METHODS:The study conducted between 2010 and 2012 in Italy enrolled adults smoke...

journal_title：BioMed research international

authors： Mannocci A,Colamesta V,Conti V,Cattaruzza MS,Paone G,Cafolla M,Saulle R,Bulzomì V,Antici D,Cuccurullo P,Boccia A,La Torre G,Terzano C

更新日期：2014-01-01 00:00:00

abstract：:This study aimed to analyse the diversity of the Campylobacter jejuni population in broilers and to evaluate the major source of contamination in poultry meat. Eight rearing cycles over one year provided samples from three different broiler farms processed at the same slaughterhouse. A total of 707 C. jejuni were isol...

journal_title：BioMed research international

authors： Marotta F,Garofolo G,Di Donato G,Aprea G,Platone I,Cianciavicchia S,Alessiani A,Di Giannatale E

更新日期：2015-01-01 00:00:00

abstract：Background:A multifactorial decision support system (mDSS) is a tool designed to improve the clinical decision-making process, while using clinical inputs for an individual patient to generate case-specific advice. The study provides an overview of the literature to analyze current available mDSS focused on prostate ca...

journal_title：BioMed research international

authors： van Wijk Y,Halilaj I,van Limbergen E,Walsh S,Lutgens L,Lambin P,Vanneste BGL

更新日期：2019-06-06 00:00:00

abstract：:Xiaoxuming decoction (XXMD), a classic traditional Chinese medicine (TCM) prescription, has been used as a therapeutic in the treatment of stroke in clinical practice for over 1200 years. However, the pharmacological mechanisms of XXMD have not yet been elucidated. The purpose of this study was to develop neuroprotect...

journal_title：BioMed research international

authors： Yang S,Shen Y,Lu W,Yang Y,Wang H,Li L,Wu C,Du G

更新日期：2019-07-10 00:00:00

abstract：:In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development. The catalytic h...

journal_title：BioMed research international

authors： Muñoz C,San Francisco J,Gutiérrez B,González J

更新日期：2015-01-01 00:00:00

abstract：Background:Flaviviridae viruses are single-stranded, positive-sense RNA viruses, which threat human constantly mediated by mosquitoes, ticks, and sandflies. Considering the recent increase in the prevalence of the family virus and its risk potential, we investigated the codon usage pattern to understand its evolutionar...

journal_title：BioMed research international

authors： Yao H,Chen M,Tang Z

更新日期：2019-06-27 00:00:00

abstract：:The aim of this study was to evaluate the safety and effectiveness of percutaneous transluminal angioplasty and stenting (PTAS) for intracranial atherosclerotic disease (ICAD) by conducting a meta-analysis. Two independent observers searched PubMed, EMBASE, and Cochrane Library for relevant studies up to 31 December 2...

journal_title：BioMed research international

authors： Li ZH,Zhou ZH,Zhu XJ,Liu W,Chen YW,Chen ZY,Liu ZJ

更新日期：2017-01-01 00:00:00

abstract：:We investigated (a) if activation of the mitogen activated protein kinase (MAPK) pathway was linked to the stress activated protein kinase (SAPK) pathway and (b) if JNK was required for activation of c-Jun in Schwann cells of rat sciatic nerve following injury. To this aim, ERK1/2 and the transcription factors c-Jun a...

journal_title：BioMed research international

authors： Blom CL,Mårtensson LB,Dahlin LB

更新日期：2014-01-01 00:00:00

abstract：:Peritoneal dialysis (PD) is associated with structural and functional alterations of the peritoneal membrane, consisting of fibrosis, angiogenesis, and loss of ultrafiltration capacity. Vitamin D receptor activation (VDRA) plays an important role in mineral metabolism and inflammation, but also antiangiogenic and anti...

journal_title：BioMed research international

authors： Stavenuiter AW,Farhat K,Vila Cuenca M,Schilte MN,Keuning ED,Paauw NJ,ter Wee PM,Beelen RH,Vervloet MG

更新日期：2015-01-01 00:00:00

abstract：:Spontaneous bacterial peritonitis (SBP) is a common cirrhotic ascites complication which exacerbates the patient's condition. SBP is caused by gram-negative bacilli and, to a lesser extent, gram-positive cocci. Hospital-acquired infections show higher levels of drug-resistant bacteria. Geographical location influences...

journal_title：BioMed research international

authors： Li YT,Huang JR,Peng ML

更新日期：2020-07-06 00:00:00

abstract：:The polyherbal formulation containing Allium sativum L., Terminalia bellirica (Gaertn.) Roxb., Curcuma aeruginosa Roxb., and Amomum compactum Sol ex. Maton has been used for hypertension treatment empirically. Our previous study showed its blood pressure-lowering effect on a rat model of hypertension. However, toxicit...

journal_title：BioMed research international

authors： Sholikhah EN,Mustofa M,Nugrahaningsih DAA,Yuliani FS,Purwono S,Sugiyono S,Widyarini S,Ngatidjan N,Jumina J,Santosa D,Koketsu M

更新日期：2020-03-24 00:00:00

abstract：Objective:Our aim was the development and validation of a modular signal processing and classification application enabling online electroencephalography (EEG) signal processing on off-the-shelf mobile Android devices. The software application SCALA (Signal ProCessing and CLassification on Android) supports a standardi...

journal_title：BioMed research international

authors： Blum S,Debener S,Emkes R,Volkening N,Fudickar S,Bleichner MG

更新日期：2017-01-01 00:00:00

abstract：:Exposure to synchronous but spatially disparate auditory and visual stimuli produces a perceptual shift of sound location towards the visual stimulus (ventriloquism effect). After adaptation to a ventriloquism situation, enduring sound shift is observed in the absence of the visual stimulus (ventriloquism aftereffect)...

journal_title：BioMed research international

authors： Magosso E,Cona F,Ursino M

更新日期：2013-01-01 00:00:00

abstract：:Cancer related fatigue (CRF) is a common and debilitating symptom that can influence quality of life (QoL) in cancer patients. The increase in survival times stresses for a better understanding of how CRF affects patients' QoL. This was a cross-sectional descriptive study with 148 randomly recruited prostate cancer pa...

journal_title：BioMed research international

authors： Charalambous A,Kouta C

更新日期：2016-01-01 00:00:00