Impact of the IL-10 Promoter Gene Polymorphisms in the Severity of Chronic Hepatitis B Infection.

abstract：BACKGROUND:There are limited data on the prevalence of the hepatitis B virus (HBV) infection in the agricultural population worldwide. OBJECTIVES:This study aimed to determine the prevalence of HBV infection and associated risk factors in the reproductive-age female farmworker. MATERIALS AND METHODS:This cross-sectio...

journal_title：Hepatitis monthly

authors： Yentur Doni N,Simsek Z,Keklik Z,Gurses G,Zeyrek FY

更新日期：2014-11-23 00:00:00

abstract：BACKGROUND:While Roux-en-Y hepaticojejunostomy (RYH) is the common anastomotic technique for liver transplantation (LT) in patients with primary sclerosing cholangitis (PSC), duct-to-duct (DD) reconstruction may be used if the recipient common bile duct is normal. There are conflicting observational data on the rate of...

journal_title：Hepatitis monthly

authors： Al-Judaibi B,Hernandez Alejandro R,Uhanova J,Marotta P,Mosli M,Chandok N

更新日期：2015-05-23 00:00:00

abstract：UNLABELLED:CONTEXTS: Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. Because less than 20% of patients with HCC are resectable, various types of non-surgical treatment have been developed. EVIDENCE ACQUISITION:At present, radiofrequency ablation (RFA) is accepted as the standa...

journal_title：Hepatitis monthly

authors： Himoto T,Kurokohchi K,Watanabe S,Masaki T

更新日期：2012-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is increasingly recognized as a major health care problem, and is found frequently in Pakistani settings. In this article we reviewed published and unpublished data related to the seroepidemiology of HCV infection in Pakistan. For this article, data from 132 published studies and thre...

journal_title：Hepatitis monthly

authors： Umar M,Bushra HT,Ahmad M,Data A,Ahmad M,Khurram M,Usman S,Arif M,Adam T,Minhas Z,Arif A,Naeem A,Ejaz K,Butt Z,Bilal M

更新日期：2010-07-01 00:00:00

abstract：CONTEXT:We briefly reviewed the evidence on the association of hepatitis C (HCV) infection with several aspects of mental and psychosocial health. EVIDENCE ACQUISITION:Medline was searched with appropriate keywords. The primary sources were the systematic reviews. If systematic reviews were not available for a subject...

journal_title：Hepatitis monthly

authors： Modabbernia A,Poustchi H,Malekzadeh R

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Nearly 0.5% of Iranians are infected with HCV. Peginterferon-alpha-2a and Peginterferon-alpha-2b are the two available types of interferon for the treatment of hepatitis C. Comparing the results of these two treatments is still a challenge. OBJECTIVES:The aim of this study was to compare the results of Pegi...

journal_title：Hepatitis monthly

authors： Pouresmaeeli M,Alavian SM,Keshvari M,Salimi S,Mehrnoush L

更新日期：2015-09-29 00:00:00

abstract：BACKGROUND:In spite of dozens of clinical trials to establish effective therapeutic and/or preventive vaccine to resolve HCV infection, no real vaccine has been proved to date. Genetic vaccines based on replication-defective adenoviruses have proved to elicit strong and long lasting T-cell responses against a number of...

journal_title：Hepatitis monthly

authors： Hosseini SY,Sabahi F,Moazzeni SM,Modarressi MH,Saberi Firoozi M,Ravanshad M

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Since directly acting antivirals (DAAs) for treatment of hepatitis C virus (HCV) were introduced, conflicting data emerged about the risk of hepatocellular carcinoma (HCC) after interferon (IFN)-free treatments. We present a case of recurrent, extra-hepatic HCC in a liver-transplanted patient soon after su...

journal_title：Hepatitis monthly

authors： Strazzulla A,Iemmolo RMR,Carbone E,Postorino MC,Mazzitelli M,De Santis M,Di Benedetto F,Cristiani CM,Costa C,Pisani V,Torti C

更新日期：2016-10-30 00:00:00

abstract：BACKGROUND:There are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (NAFLD) in different populations. However, the existing literature lacks powerful studies addressing the factors which may predict the severity of NAFLD. OBJECTIVES:In the current study, we a...

journal_title：Hepatitis monthly

authors： Ghamar-Chehreh ME,Khedmat H,Amini M,Taheri S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Hepatitis A, a fecal-oral transmitted disease, which has been considered endemic in developing countries, seems to change its pattern in developing countries because of their improved socioeconomic status. OBJECTIVES:In the present study, we aimed to determine the need of vaccination in 270 students at AJA ...

journal_title：Hepatitis monthly

authors： Hosseini Shokouh SJ,Dadashi A,Abiri M,Zohrevand I,Eshraghian A,Khoshdel A,Heidari B,Khoshkish S

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:About 30% of individuals with hepatitis C virus (HCV) infection are able to clear HCV spontaneously. Differences in host genetics affect the outcome of HCV infection. Single nucleotide polymorphisms (SNPs) of the Interferon lambda (IFNL) genes were associated with spontaneous and treatment-induced clearance ...

journal_title：Hepatitis monthly

authors： Sharafi H,Alavian SM,Behnava B,Pouryasin A,Keshvari M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Primary sclerosing cholangitis (PSC) as one of the most common chronic cholestatic liver diseases is a main predisposing factor for the development of cholangiocarcinoma (CCA). Biliary intraepithelial neoplasia (BilIN) is defined as precancerous bile duct epithelial changes, which can be eventually led to ch...

journal_title：Hepatitis monthly

authors： Akbarzadeh L,Geramizadeh B,Kazemi K,Nikeghbalian S,Malekhosseini S

更新日期：2016-12-14 00:00:00

abstract：BACKGROUND:The prevalence of hepatitis C in Iran is 1% and 18% in general population and thalassemia patients respectively. The cost effectiveness analysis of adding Ribavirin to Peginterferon alfa-2a (PEG IFN alfa-2a) as a combination treatment strategy of chronic hepatitis C in thalassemia patients in comparison with...

journal_title：Hepatitis monthly

authors： Mehrazmay A,Alavian SM,Moradi-Lakeh M,Mokhtari Payam M,Hashemi-Meshkini A,Behnava B,Miri SM,Karimi Elizee P,Tabatabaee SV,Keshvari M,Bagheri Lankarani K

更新日期：2013-09-01 00:00:00

abstract：:Patients with chronic hepatitis B infection should be followed up to identify possible changes in disease status, such as HBsAg seronversion. There are little data on the outcome of such cases, and the response rate to HBV vaccine has not been discussed extensively. ...

journal_title：Hepatitis monthly

authors： Alavian SM,Miri SM

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:There have been very few studies evaluating the close association between excess iron and cirrhosis; however, cirrhosis could be regarded as an iron-loading disorder. OBJECTIVES:In this study, the goal was to show the levels of the iron content in the liver tissue in certain types of cirrhosis. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Geramizadeh B,Ghazanfari Y,Nikeghbalian S,Malekhosseini SA

更新日期：2015-12-28 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV), hepatitis D virus (HDV), and human immunodeficiency virus (HIV) are transmitted by blood transfusion. Thus, hemodialysis (HD) patients are more prone to become the carriers of these infections due to their treatment demands. OBJECTIVES:The aim of this study was to assess the prevale...

journal_title：Hepatitis monthly

authors： Bahri F,Kargar Kheirabad A,Ghasemzadeh I,Shoja S,Gouklani H

更新日期：2016-01-23 00:00:00

abstract：BACKGROUND:Genetic polymorphisms may play role in the pathophysiology of nonalcoholic steatohepatitis (NASH). OBJECTIVES:We purposed to assess the role of interleukin 6 (IL 6) and interleukin 8 (IL 8) gene polymorphisms in the pathogenesis of NASH. PATIENTS AND METHODS:Consecutive patients with biopsy proven NASH and...

journal_title：Hepatitis monthly

authors： Cengiz M,Yasar DG,Ergun MA,Akyol G,Ozenirler S

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:Viral hepatitis caused by hepatitis B virus (HBV) is a leading cause of acute and chronic liver diseases worldwide. OBJECTIVES:In Italy, a mandatory vaccination policy was introduced in 1991 and was established for all newborns and 12-year-old individuals. In 2004, vaccination of 12-year old adolescents was...

journal_title：Hepatitis monthly

authors： Campagna M,Siddu A,Meloni A,Murru C,Masia G,Coppola RC

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Human leukocyte antigen (HLA) typing in autoimmune hepatitis (AIH) has been investigated in different populations and ethnic groups, but no such data is available from Pakistan. OBJECTIVES:The aim of this study was to evaluate the clinical profile of autoimmune hepatitis (AIH), and determine the associated ...

journal_title：Hepatitis monthly

authors： Hassan N,Siddiqui AR,Abbas Z,Hassan SM,Soomro GB,Mubarak M,Anis S,Muzaffar R,Zafar MN

更新日期：2013-12-16 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) is able to down-regulate innate immune response. It is important to know the immune pathways that this virus interacts with. HCV non-structural protein 3 (NS3) plays an important role in this viral feature. HCV NS3 protein could affect the expression of antiviral protein such as viper...

journal_title：Hepatitis monthly

authors： Khanlari Z,Sabahi F,Hosseini SY,Ghaderi M

更新日期：2014-06-08 00:00:00

abstract：BACKGROUND:Global prevalence of Hepatitis C Virus (HCV) infection corresponds to about 130 million HCV positive patients worldwide. The only drug that effectively reduces viral load is interferon-α (IFN-α) and currently combination of IFN and ribavirin is the choice for treatment. OBJECTIVES:The present study is aimed...

journal_title：Hepatitis monthly

authors： Kanwal S,Mahmood T

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Approximately 5% of hepatitis B virus (HBV) carriers are coinfected with hepatitis D virus (HDV). HBV/HDV coinfection is a major cause of cirrhosis and end stage liver disease in chronic HBsAg carriers. The only approved therapy for chronic hepatitis delta is interferon alpha (IFN α) in either pegylated or c...

journal_title：Hepatitis monthly

authors： Keshvari M,Alavian SM,Sharafi H,Karimi G,Gholami Fesharaki M

更新日期：2014-03-01 00:00:00

abstract：BACKGROUNDS:Serum hepatitis B surface antigen (HBsAg) levels are associated with fibrosis in patients with chronic hepatitis B (CHB) infection. OBJECTIVES:The aim of our study was to evaluate serum HBsAg level as a biomarker for compensated cirrhosis in hepatitis B e antigen (HBeAg) positive CHB patients. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Jia W,Qi X,Ji YY,Xun YH,Wang H,Zhang WH,Yang JH,Wang JY,Zhu HX,Mao RC,Zhang JM

更新日期：2015-08-30 00:00:00

abstract：BACKGROUND:Cytokines are proteins that mediate innate and adaptive immunity responses. It is hypothesized that interferon lambda 3 (IFNL3) levels can influence the outcome of chronic hepatitis B virus (HBV) infection. Polymorphisms in IFN genes have been associated with response to infection. OBJECTIVES:This study was...

journal_title：Hepatitis monthly

authors： Heidari Z,Moudi B,Mahmoudzadeh-Sagheb H,Hashemi M

更新日期：2016-03-05 00:00:00

abstract：BACKGROUND:The hepatitis B virus (HBV) antigen-induced cellular immune response plays an important role in HBV clearance. Changes in the diversity of complementarity determining region 3 (CDR3) and T-cell receptor (TCR) sequences are used to monitor the response of T cells to antigens. OBJECTIVES:The aim of the presen...

journal_title：Hepatitis monthly

authors： Xiong Y,Tan Y,Song YG

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:Serum apoptotic cytokeratine 18 neoepitope M30 (CK-18 M30) and matrix metalloproteinase 2 (MMP-2) have been popular markers for detecting liver fibrosis in recent years. CK-18 is a major intermediate filament protein in liver cells and one of the most prominent substrates of caspases during hepatocyte apopto...

journal_title：Hepatitis monthly

authors： Sumer S,Aktug Demir N,Kölgelier S,Cagkan Inkaya A,Arpaci A,Saltuk Demir L,Ural O

更新日期：2013-06-26 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection as a worldwide health problem is associated with cirrhosis and hepatocellular carcinoma. With current treatment regimen, pegylated interferon (PEG-IFN) plus ribavirin, sustain virological response (SVR) is achieved in only 50% of infected individuals. In HCV infection, an in...

journal_title：Hepatitis monthly

authors： Sarvari J,Norozian H,Fattahi MR,Pirbonyeh N,Moattari A

更新日期：2014-01-23 00:00:00

abstract：BACKGROUND:Cyclosporine A (CsA)-induced hepatotoxicity could be due to a reduction in α2β1 integrin expression that may either be from the direct effect of CsA itself or from reactive oxygen species (ROS) overproduction. OBJECTIVES:In this study we aimed to identify the cellular mechanisms underlying CsA-induced hepat...

journal_title：Hepatitis monthly

authors： Mostafavi-Pour Z,Khademi F,Zal F,Sardarian AR,Amini F

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in western world. However, NAFLD shows an increasing trend in China every year, which has attracted the attention of national health authorities. The previous studies have shown that NAFLD caused severe gastrointestina...

journal_title：Hepatitis monthly

authors： Lu ML,Huang H,Liu LM,Chang J

更新日期：2013-10-01 00:00:00

abstract：CONTEXT:The modern practice of anesthesia is highly dependent ona group of anesthetic drugs which many of them are metabolized in the liver. EVIDENCE ACQUISITION:The liver, of course, usually tolerates this burden. However, this is not always an unbroken rule. Anesthetic induced apoptosis has gained great concern duri...

journal_title：Hepatitis monthly

authors： Dabbagh A,Rajaei S

更新日期：2013-08-25 00:00:00