Low Serum Hepatitis B Surface Antigen Level Predicts Compensated Cirrhosis Caused by Chronic Hepatitis B in HBeAg Positive Patients in East China.

abstract：BACKGROUND:There are limited data on the prevalence of the hepatitis B virus (HBV) infection in the agricultural population worldwide. OBJECTIVES:This study aimed to determine the prevalence of HBV infection and associated risk factors in the reproductive-age female farmworker. MATERIALS AND METHODS:This cross-sectio...

journal_title：Hepatitis monthly

authors： Yentur Doni N,Simsek Z,Keklik Z,Gurses G,Zeyrek FY

更新日期：2014-11-23 00:00:00

abstract：BACKGROUND:There is growing evidence suggesting that interleukin-18 (IL-18) plays a crucial role in viral clearance and disease pathogenesis, and that single nucleotide polymorphisms (SNPs) within the gene may influence its production. OBJECTIVES:To investigate the potential association of two polymorphisms ( 137G/C a...

journal_title：Hepatitis monthly

authors： Wu L,Chen L,Zhou L,Xie H,Wei B,Yin S,Ye Y,Fang W,Zheng S

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Precore stop codon (G1896A) mutation is one of the commonest mutations found in patients with chronic hepatitis B. However, over the years, this mutation was not reported much in Malaysia. OBJECTIVES:We therefore investigated the presence of G1896A mutation in Malaysian population and its association with H...

journal_title：Hepatitis monthly

authors： Suppiah J,Mohd Zain R,Bahari N,Haji Nawi S,Saat Z

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:The prevalence of newly-diagnosed cases of chronic hepatitis is decisive for the overall incidence rate of hepatitis B observed in Poland. OBJECTIVES:We aimed to determine the chronic hepatitis B incidence trends in Poland, taking into consideration the ages, genders, and environments of the patients. METH...

journal_title：Hepatitis monthly

authors： Stawinska-Witoszynska B,Zysnarska M,Krzywinska-Wiewiorowska M,Wojtyła-Buciorab P,Krzyzaniak A,Wieckowska B

更新日期：2016-07-25 00:00:00

abstract：:Approximately 170 million people worldwide are chronically infected by hepatitis C virus (HCV), which can result in progressive hepatic injury and fibrosis, culminating in cirrhosis and end-stage liver disease. The benchmark therapy for untreated HCV patients is a combination of pegylated interferon-alpha (PEG-IFN) an...

journal_title：Hepatitis monthly

authors： Abenavoli L,Mazza M,Almasio PL

更新日期：2011-04-01 00:00:00

abstract：:Patients with chronic hepatitis B infection should be followed up to identify possible changes in disease status, such as HBsAg seronversion. There are little data on the outcome of such cases, and the response rate to HBV vaccine has not been discussed extensively. ...

journal_title：Hepatitis monthly

authors： Alavian SM,Miri SM

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Nearly 0.5% of Iranians are infected with HCV. Peginterferon-alpha-2a and Peginterferon-alpha-2b are the two available types of interferon for the treatment of hepatitis C. Comparing the results of these two treatments is still a challenge. OBJECTIVES:The aim of this study was to compare the results of Pegi...

journal_title：Hepatitis monthly

authors： Pouresmaeeli M,Alavian SM,Keshvari M,Salimi S,Mehrnoush L

更新日期：2015-09-29 00:00:00

abstract：INTRODUCTION:Since directly acting antivirals (DAAs) for treatment of hepatitis C virus (HCV) were introduced, conflicting data emerged about the risk of hepatocellular carcinoma (HCC) after interferon (IFN)-free treatments. We present a case of recurrent, extra-hepatic HCC in a liver-transplanted patient soon after su...

journal_title：Hepatitis monthly

authors： Strazzulla A,Iemmolo RMR,Carbone E,Postorino MC,Mazzitelli M,De Santis M,Di Benedetto F,Cristiani CM,Costa C,Pisani V,Torti C

更新日期：2016-10-30 00:00:00

abstract：BACKGROUND:Zinc deficiency has been reported frequently in hepatitis C patients in the literature. Furthermore, a decrease in zinc level has been shown in beta thalassemia major as well. Iranians consume a large amount of phytate in their regimens which can bind with zinc and decrease its gastrointestinal absorption. ...

journal_title：Hepatitis monthly

authors： Abbasinazari M,Behnava B,Panahi Y,Hajhossein Talasaz A,Salimi S,Keshvari M,Mehrnoush L,Karim Elizee P,Gholami Fesharaki M,Asgharinia M,Alavian SM

更新日期：2013-08-12 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) genotypes and mutations are gaining importance in determining the clinical course of chronic liver disease. OBJECTIVES:To determine and compare the distribution of HBV genotypes and genomic variations in Pakistan to other parts of the world. PATIENTS AND METHODS:We conducted a prosp...

journal_title：Hepatitis monthly

authors： Mumtaz K,Hamid S,Ahmed S,Moatter T,Mushtaq S,Khan A,Mizokami M,Jafri W

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:There have been very few studies evaluating the close association between excess iron and cirrhosis; however, cirrhosis could be regarded as an iron-loading disorder. OBJECTIVES:In this study, the goal was to show the levels of the iron content in the liver tissue in certain types of cirrhosis. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Geramizadeh B,Ghazanfari Y,Nikeghbalian S,Malekhosseini SA

更新日期：2015-12-28 00:00:00

abstract：BACKGROUND:Genetic polymorphisms may play role in the pathophysiology of nonalcoholic steatohepatitis (NASH). OBJECTIVES:We purposed to assess the role of interleukin 6 (IL 6) and interleukin 8 (IL 8) gene polymorphisms in the pathogenesis of NASH. PATIENTS AND METHODS:Consecutive patients with biopsy proven NASH and...

journal_title：Hepatitis monthly

authors： Cengiz M,Yasar DG,Ergun MA,Akyol G,Ozenirler S

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:Global prevalence of Hepatitis C Virus (HCV) infection corresponds to about 130 million HCV positive patients worldwide. The only drug that effectively reduces viral load is interferon-α (IFN-α) and currently combination of IFN and ribavirin is the choice for treatment. OBJECTIVES:The present study is aimed...

journal_title：Hepatitis monthly

authors： Kanwal S,Mahmood T

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Human leukocyte antigen (HLA) typing in autoimmune hepatitis (AIH) has been investigated in different populations and ethnic groups, but no such data is available from Pakistan. OBJECTIVES:The aim of this study was to evaluate the clinical profile of autoimmune hepatitis (AIH), and determine the associated ...

journal_title：Hepatitis monthly

authors： Hassan N,Siddiqui AR,Abbas Z,Hassan SM,Soomro GB,Mubarak M,Anis S,Muzaffar R,Zafar MN

更新日期：2013-12-16 00:00:00

abstract：BACKGROUND:Cytokines are proteins that mediate innate and adaptive immunity responses. It is hypothesized that interferon lambda 3 (IFNL3) levels can influence the outcome of chronic hepatitis B virus (HBV) infection. Polymorphisms in IFN genes have been associated with response to infection. OBJECTIVES:This study was...

journal_title：Hepatitis monthly

authors： Heidari Z,Moudi B,Mahmoudzadeh-Sagheb H,Hashemi M

更新日期：2016-03-05 00:00:00

abstract：BACKGROUND:Hepatitis B infections, characterized by the presence of a viral genome without detectable hepatitis B surface antigen (HBsAg; Occult hepatitis B infection [OBI]), have been reported recently. OBJECTIVES:We performed serological and molecular characterization of OBI among blood donors at Jiangsu province bl...

journal_title：Hepatitis monthly

authors： Lin H,Zhao H,Tang X,Hu W,Jiang N,Zhu S,Huang C

更新日期：2016-10-02 00:00:00

abstract：BACKGROUND:Hepatitis C virus infection is one of the leading causes of end stage liver diseases. The innate immune response slows down viral replication by activating cytokines such as type I interferon (IFN-α/β), which trigger the synthesis of antiviral proteins and modulate the adaptive immune system. Recently, leuci...

journal_title：Hepatitis monthly

authors： Liu Y,Zou Z,Zhu B,Hu Z,Zeng P,Wu L

更新日期：2015-05-23 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) is able to down-regulate innate immune response. It is important to know the immune pathways that this virus interacts with. HCV non-structural protein 3 (NS3) plays an important role in this viral feature. HCV NS3 protein could affect the expression of antiviral protein such as viper...

journal_title：Hepatitis monthly

authors： Khanlari Z,Sabahi F,Hosseini SY,Ghaderi M

更新日期：2014-06-08 00:00:00

abstract：CONTEXT:Hepatitis B vaccination of hemodialysis patients is performed all over the world. There are also recommendations from world health organizations to vaccinate patients with chronic kidney disease (CKD) prior dialysis commencement, but the implementation of a hepatitis B vaccination program is less common and not...

journal_title：Hepatitis monthly

authors： Grzegorzewska AE

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Treatment of hepatitis C virus (HCV) infection with interferon (IFN) and ribavirin (RBV) is associated with adverse events, which may affect the patient's adherence to the treatment regimen and the treatment efficacy. OBJECTIVES:The aim of this study was to assess the sustained viral response (SVR) and inte...

journal_title：Hepatitis monthly

authors： Pawlowska M,Pilarczyk M,Foksinska A,Smukalska E,Halota W

更新日期：2011-12-01 00:00:00

abstract：CONTEXT:We briefly reviewed the evidence on the association of hepatitis C (HCV) infection with several aspects of mental and psychosocial health. EVIDENCE ACQUISITION:Medline was searched with appropriate keywords. The primary sources were the systematic reviews. If systematic reviews were not available for a subject...

journal_title：Hepatitis monthly

authors： Modabbernia A,Poustchi H,Malekzadeh R

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The hepatitis B virus (HBV) antigen-induced cellular immune response plays an important role in HBV clearance. Changes in the diversity of complementarity determining region 3 (CDR3) and T-cell receptor (TCR) sequences are used to monitor the response of T cells to antigens. OBJECTIVES:The aim of the presen...

journal_title：Hepatitis monthly

authors： Xiong Y,Tan Y,Song YG

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV), hepatitis D virus (HDV), and human immunodeficiency virus (HIV) are transmitted by blood transfusion. Thus, hemodialysis (HD) patients are more prone to become the carriers of these infections due to their treatment demands. OBJECTIVES:The aim of this study was to assess the prevale...

journal_title：Hepatitis monthly

authors： Bahri F,Kargar Kheirabad A,Ghasemzadeh I,Shoja S,Gouklani H

更新日期：2016-01-23 00:00:00

abstract：BACKGROUND:Non-invasive methods for assessment of hepatic fibrosis are increasingly needed. Recent studies showed that combined elevation of tumor markers CA 19-9 and CA 125 is predictive of severe hepatic fibrosis or cirrhosis with high specificity. OBJECTIVES:We aimed at developing a new panel of surrogate biomarker...

journal_title：Hepatitis monthly

authors： Alboraie MA,Afifi ME,Elghamry FG,Shalaby HA,Elshennawy GE,Abdelaziz AA,Shaheen MU,Abo El-Seoud AR

更新日期：2013-06-16 00:00:00

abstract：BACKGROUND:In Iran, the number of injecting drug users (IDUs) has increased in recent years. The rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections among IDUs are reportedly high. OBJECTIVES:The purpose of this study was to assess factors correlated with HCV and HBV infections among IDUs in Tehran...

journal_title：Hepatitis monthly

authors： Amin-Esmaeili M,Rahimi-Movaghar A,Razaghi EM,Baghestani AR,Jafari S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Cyclosporine A (CsA)-induced hepatotoxicity could be due to a reduction in α2β1 integrin expression that may either be from the direct effect of CsA itself or from reactive oxygen species (ROS) overproduction. OBJECTIVES:In this study we aimed to identify the cellular mechanisms underlying CsA-induced hepat...

journal_title：Hepatitis monthly

authors： Mostafavi-Pour Z,Khademi F,Zal F,Sardarian AR,Amini F

更新日期：2013-08-13 00:00:00

abstract：CONTEXT:Cystic fibrosis (CF) is the most widespread autosomal recessive genetic disorder that limits life expectation amongst the Caucasian population. As the median survival has increased related to early multidisciplinary intervention, other manifestations of CF have emerged especially for the broad spectrum of hepat...

journal_title：Hepatitis monthly

authors： Parisi GF,Di Dio G,Franzonello C,Gennaro A,Rotolo N,Lionetti E,Leonardi S

更新日期：2013-08-14 00:00:00

abstract：BACKGROUND AND AIMS:The duration of the protection of hepatitis B vaccination for infants and the necessity of a booster dose administration is unknown. The aim of the present study was to evaluate the persistence of seroprotection after hepatitis B virus (HBV) vaccination in order to determine the necessity of a singl...

journal_title：Hepatitis monthly

authors： Yazdanpanah B,Safari M,Yazdanpanah S

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Chronic viral hepatitis can be evaluated using invasive or noninvasive methods. OBJECTIVES:The aim of this study was to evaluate liver stiffness in inactive HBsAg carriers compared with normal subjects and determine if it is influenced by viral load in these patients. PATIENTS AND METHODS:We prospectively ...

journal_title：Hepatitis monthly

authors： Sporea I,Nicolita D,Sirli R,Deleanu A,Tudora A,Bota S

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Reversibility of advanced fibrosis after HCV-clearance is an important goal of therapy. OBJECTIVES:Measuring liver stiffness (LS) by transient elastography (TE) might be helpful in this setting. PATIENTS AND METHODS:We evaluated 104 patients with biopsy-proven chronic hepatitis C (CHC) and sustained virolo...

journal_title：Hepatitis monthly

authors： Calvaruso V,Di Marco V,Ferraro D,Petta S,Calì A,Grazia Bavetta M,Conte E,Luigi Almasio P

更新日期：2013-05-11 00:00:00