The Risk of Hepatocellular Carcinoma After Directly Acting Antivirals for Hepatitis C Virus Treatment in Liver Transplanted Patients: Is It Real?

abstract：BACKGROUND:While Roux-en-Y hepaticojejunostomy (RYH) is the common anastomotic technique for liver transplantation (LT) in patients with primary sclerosing cholangitis (PSC), duct-to-duct (DD) reconstruction may be used if the recipient common bile duct is normal. There are conflicting observational data on the rate of...

journal_title：Hepatitis monthly

authors： Al-Judaibi B,Hernandez Alejandro R,Uhanova J,Marotta P,Mosli M,Chandok N

更新日期：2015-05-23 00:00:00

abstract：BACKGROUND:Hepatitis viruses are one of the most important concerns in the patients on hemodialysis who are at high risk for blood-borne infections. GB virus C (GBV-C)/hepatitis G virus (HGV) is positive-stranded RNA virus with global distribution, which codes structural and nonstructural proteins (such as NS3). OBJEC...

journal_title：Hepatitis monthly

authors： Dadmanesh M,Ranjbar MM,Alavian SM,Ghorban K

更新日期：2015-03-05 00:00:00

abstract：BACKGROUND:During antiviral therapy for chronic hepatitis B, renal function impairment could be a critical concern when oral nucleot(s)ide analogues were used. Paradoxically, long-term telbivudine treatment was associated with an increase of estimated glomerular filtration rate (eGFR) through unknown mechanisms. OBJEC...

journal_title：Hepatitis monthly

authors： Liang KH,Chen YC,Hsu CW,Chang ML,Yeh CT

更新日期：2014-01-31 00:00:00

abstract：BACKGROUND:Precore stop codon (G1896A) mutation is one of the commonest mutations found in patients with chronic hepatitis B. However, over the years, this mutation was not reported much in Malaysia. OBJECTIVES:We therefore investigated the presence of G1896A mutation in Malaysian population and its association with H...

journal_title：Hepatitis monthly

authors： Suppiah J,Mohd Zain R,Bahari N,Haji Nawi S,Saat Z

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:Hepatitis A, a fecal-oral transmitted disease, which has been considered endemic in developing countries, seems to change its pattern in developing countries because of their improved socioeconomic status. OBJECTIVES:In the present study, we aimed to determine the need of vaccination in 270 students at AJA ...

journal_title：Hepatitis monthly

authors： Hosseini Shokouh SJ,Dadashi A,Abiri M,Zohrevand I,Eshraghian A,Khoshdel A,Heidari B,Khoshkish S

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:Non-invasive methods for assessment of hepatic fibrosis are increasingly needed. Recent studies showed that combined elevation of tumor markers CA 19-9 and CA 125 is predictive of severe hepatic fibrosis or cirrhosis with high specificity. OBJECTIVES:We aimed at developing a new panel of surrogate biomarker...

journal_title：Hepatitis monthly

authors： Alboraie MA,Afifi ME,Elghamry FG,Shalaby HA,Elshennawy GE,Abdelaziz AA,Shaheen MU,Abo El-Seoud AR

更新日期：2013-06-16 00:00:00

abstract：BACKGROUND:In chronic liver diseases, a correct estimation of the severity of liver fibrosis is important for recommendations regarding the treatment. Nowadays, evaluation of fibrosis is done by noninvasive methods such as biochemical scores and transient elastography instead of liver biopsy. The lack of sensitivity to...

journal_title：Hepatitis monthly

authors： Sporea I,Badea R,Sirli R,Lupsor M,Popescu A,Danila M,Focsa M,Deleanu A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Reversibility of advanced fibrosis after HCV-clearance is an important goal of therapy. OBJECTIVES:Measuring liver stiffness (LS) by transient elastography (TE) might be helpful in this setting. PATIENTS AND METHODS:We evaluated 104 patients with biopsy-proven chronic hepatitis C (CHC) and sustained virolo...

journal_title：Hepatitis monthly

authors： Calvaruso V,Di Marco V,Ferraro D,Petta S,Calì A,Grazia Bavetta M,Conte E,Luigi Almasio P

更新日期：2013-05-11 00:00:00

abstract：BACKGROUND:Viral hepatitis is a major health problem in Brazil and worldwide. The state of Santa Catarina has high endemic areas, and the disease burden is unknown. OBJECTIVES:To estimate and analyze the burden of hepatitis B in the state of Santa Catarina, in 2005 - 2010. MATERIALS AND METHODS:A time-series analysis...

journal_title：Hepatitis monthly

authors： Marcon CE,Schneider IJ,Schuelter-Trevisol F,Traebert J

更新日期：2015-11-28 00:00:00

abstract：BACKGROUND:Chronic hepatitis C (CHC) is a global infection. In Saudi Arabia, the prevalence of CHC is declining due to the implementation of a blood screening program. However, CHC still remains a leading cause of liver cirrhosis and hepatocellular carcinoma. OBJECTIVES:This is a retrospective study of CHC patients at...

journal_title：Hepatitis monthly

authors： Akbar HO,Al Ghamdi A,Qattan F,Fallatah HI,Al Rumani M

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The prevalence of hepatitis C in Iran is 1% and 18% in general population and thalassemia patients respectively. The cost effectiveness analysis of adding Ribavirin to Peginterferon alfa-2a (PEG IFN alfa-2a) as a combination treatment strategy of chronic hepatitis C in thalassemia patients in comparison with...

journal_title：Hepatitis monthly

authors： Mehrazmay A,Alavian SM,Moradi-Lakeh M,Mokhtari Payam M,Hashemi-Meshkini A,Behnava B,Miri SM,Karimi Elizee P,Tabatabaee SV,Keshvari M,Bagheri Lankarani K

更新日期：2013-09-01 00:00:00

abstract：UNLABELLED:CONTEXTS: Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. Because less than 20% of patients with HCC are resectable, various types of non-surgical treatment have been developed. EVIDENCE ACQUISITION:At present, radiofrequency ablation (RFA) is accepted as the standa...

journal_title：Hepatitis monthly

authors： Himoto T,Kurokohchi K,Watanabe S,Masaki T

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Patients with HBeAg-negative chronic hepatitis B (CHB) has a significantly different prognosis than inactive carriers; there is however, no reliable strategy for accurately differentiating these two disease conditions. OBJECTIVES:To determine a strategy for discriminating patients with HBeAg-negative CHB fr...

journal_title：Hepatitis monthly

authors： Kim ES,Seo YS,Keum B,Kim JH,A H,Yim HJ,Kim YS,Jeen YT,Lee HS,Chun HJ,Um SH,Duck Kim C,Ryu HS

更新日期：2011-05-01 00:00:00

abstract：CONTEXT:The modern practice of anesthesia is highly dependent ona group of anesthetic drugs which many of them are metabolized in the liver. EVIDENCE ACQUISITION:The liver, of course, usually tolerates this burden. However, this is not always an unbroken rule. Anesthetic induced apoptosis has gained great concern duri...

journal_title：Hepatitis monthly

authors： Dabbagh A,Rajaei S

更新日期：2013-08-25 00:00:00

abstract：BACKGROUND:In spite of dozens of clinical trials to establish effective therapeutic and/or preventive vaccine to resolve HCV infection, no real vaccine has been proved to date. Genetic vaccines based on replication-defective adenoviruses have proved to elicit strong and long lasting T-cell responses against a number of...

journal_title：Hepatitis monthly

authors： Hosseini SY,Sabahi F,Moazzeni SM,Modarressi MH,Saberi Firoozi M,Ravanshad M

更新日期：2012-08-01 00:00:00

abstract：:Approximately 170 million people worldwide are chronically infected by hepatitis C virus (HCV), which can result in progressive hepatic injury and fibrosis, culminating in cirrhosis and end-stage liver disease. The benchmark therapy for untreated HCV patients is a combination of pegylated interferon-alpha (PEG-IFN) an...

journal_title：Hepatitis monthly

authors： Abenavoli L,Mazza M,Almasio PL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus infection is one of the leading causes of end stage liver diseases. The innate immune response slows down viral replication by activating cytokines such as type I interferon (IFN-α/β), which trigger the synthesis of antiviral proteins and modulate the adaptive immune system. Recently, leuci...

journal_title：Hepatitis monthly

authors： Liu Y,Zou Z,Zhu B,Hu Z,Zeng P,Wu L

更新日期：2015-05-23 00:00:00

abstract：BACKGROUND:Cyclosporine A (CsA)-induced hepatotoxicity could be due to a reduction in α2β1 integrin expression that may either be from the direct effect of CsA itself or from reactive oxygen species (ROS) overproduction. OBJECTIVES:In this study we aimed to identify the cellular mechanisms underlying CsA-induced hepat...

journal_title：Hepatitis monthly

authors： Mostafavi-Pour Z,Khademi F,Zal F,Sardarian AR,Amini F

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:The entire disease spectrum of chronic HBV infection (CHB) includes asymptomatic carriers (AC), active chronic hepatitis (ACH), cirrhosis (Cir), and hepatocellular carcinoma (HCC). Previous study have demonstrated that the costimulation profiles from the livers of patients influenced immune responses and pla...

journal_title：Hepatitis monthly

authors： Yin JW,Ping Huang M,Zhong B

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) is able to down-regulate innate immune response. It is important to know the immune pathways that this virus interacts with. HCV non-structural protein 3 (NS3) plays an important role in this viral feature. HCV NS3 protein could affect the expression of antiviral protein such as viper...

journal_title：Hepatitis monthly

authors： Khanlari Z,Sabahi F,Hosseini SY,Ghaderi M

更新日期：2014-06-08 00:00:00

abstract：CONTEXT:Cystic fibrosis (CF) is the most widespread autosomal recessive genetic disorder that limits life expectation amongst the Caucasian population. As the median survival has increased related to early multidisciplinary intervention, other manifestations of CF have emerged especially for the broad spectrum of hepat...

journal_title：Hepatitis monthly

authors： Parisi GF,Di Dio G,Franzonello C,Gennaro A,Rotolo N,Lionetti E,Leonardi S

更新日期：2013-08-14 00:00:00

abstract：BACKGROUND:Human leukocyte antigen (HLA) typing in autoimmune hepatitis (AIH) has been investigated in different populations and ethnic groups, but no such data is available from Pakistan. OBJECTIVES:The aim of this study was to evaluate the clinical profile of autoimmune hepatitis (AIH), and determine the associated ...

journal_title：Hepatitis monthly

authors： Hassan N,Siddiqui AR,Abbas Z,Hassan SM,Soomro GB,Mubarak M,Anis S,Muzaffar R,Zafar MN

更新日期：2013-12-16 00:00:00

abstract：BACKGROUND:GB virus C (GBV-C) or hepatitis G virus (HGV) is a newly discovered and enveloped RNA positive-stranded flavivirus-like particle, which has not yet been proven to have major negative effects on liver. OBJECTIVES:Increasing the risk of blood-borne infections in hemodialysis patients is a main health care con...

journal_title：Hepatitis monthly

authors： Dadmanesh M,Hosseinzadeh M,Keyvani H,Ghorban K,Rahimi M,Hosseinzadeh M,Ranjbar MM

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The prevalence of newly-diagnosed cases of chronic hepatitis is decisive for the overall incidence rate of hepatitis B observed in Poland. OBJECTIVES:We aimed to determine the chronic hepatitis B incidence trends in Poland, taking into consideration the ages, genders, and environments of the patients. METH...

journal_title：Hepatitis monthly

authors： Stawinska-Witoszynska B,Zysnarska M,Krzywinska-Wiewiorowska M,Wojtyła-Buciorab P,Krzyzaniak A,Wieckowska B

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:There are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (NAFLD) in different populations. However, the existing literature lacks powerful studies addressing the factors which may predict the severity of NAFLD. OBJECTIVES:In the current study, we a...

journal_title：Hepatitis monthly

authors： Ghamar-Chehreh ME,Khedmat H,Amini M,Taheri S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Hepatitis B is a common infectious disease in China. Many studies have shown that the genotype of hepatitis B virus (HBV) is probably associated with the efficacy of some antiviral drugs such as interferon α (IFN-α) and Lamivudine (LAM). However, the association between HBV genotype and adefovir dipivoxil (A...

journal_title：Hepatitis monthly

authors： Wen Z,Zhang H,Zhang M,Tan D,Li Q,Zhang H,Wu P,Deng L

更新日期：2014-08-17 00:00:00

abstract：BACKGROUNDS:Serum hepatitis B surface antigen (HBsAg) levels are associated with fibrosis in patients with chronic hepatitis B (CHB) infection. OBJECTIVES:The aim of our study was to evaluate serum HBsAg level as a biomarker for compensated cirrhosis in hepatitis B e antigen (HBeAg) positive CHB patients. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Jia W,Qi X,Ji YY,Xun YH,Wang H,Zhang WH,Yang JH,Wang JY,Zhu HX,Mao RC,Zhang JM

更新日期：2015-08-30 00:00:00

abstract：BACKGROUND:Infection with the hepatitis B virus (HBV) is an important global health problem. Knowledge of the geographic distribution pattern of HBV infection can help to control the spread of the disease. OBJECTIVES:To determine the prevalence of HBV infections and risk factors for the disease for the first time in B...

journal_title：Hepatitis monthly

authors： Ziaee M,Ebrahimzadeh A,Azarkar Z,Namaei MH,Saburi A,Fereidouni M,Bijari B,Karamian M,Sharifzadeh G

更新日期：2016-08-14 00:00:00

abstract：BACKGROUND:Treatment of hepatitis C virus (HCV) infection with interferon (IFN) and ribavirin (RBV) is associated with adverse events, which may affect the patient's adherence to the treatment regimen and the treatment efficacy. OBJECTIVES:The aim of this study was to assess the sustained viral response (SVR) and inte...

journal_title：Hepatitis monthly

authors： Pawlowska M,Pilarczyk M,Foksinska A,Smukalska E,Halota W

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in western world. However, NAFLD shows an increasing trend in China every year, which has attracted the attention of national health authorities. The previous studies have shown that NAFLD caused severe gastrointestina...

journal_title：Hepatitis monthly

authors： Lu ML,Huang H,Liu LM,Chang J

更新日期：2013-10-01 00:00:00