Chronic hepatitis C in saudi arabia: three years local experience in a university hospital.

abstract：BACKGROUND:Infection with the hepatitis B virus (HBV) is an important global health problem. Knowledge of the geographic distribution pattern of HBV infection can help to control the spread of the disease. OBJECTIVES:To determine the prevalence of HBV infections and risk factors for the disease for the first time in B...

journal_title：Hepatitis monthly

authors： Ziaee M,Ebrahimzadeh A,Azarkar Z,Namaei MH,Saburi A,Fereidouni M,Bijari B,Karamian M,Sharifzadeh G

更新日期：2016-08-14 00:00:00

abstract：BACKGROUND:Nearly 0.5% of Iranians are infected with HCV. Peginterferon-alpha-2a and Peginterferon-alpha-2b are the two available types of interferon for the treatment of hepatitis C. Comparing the results of these two treatments is still a challenge. OBJECTIVES:The aim of this study was to compare the results of Pegi...

journal_title：Hepatitis monthly

authors： Pouresmaeeli M,Alavian SM,Keshvari M,Salimi S,Mehrnoush L

更新日期：2015-09-29 00:00:00

abstract：BACKGROUND:Interleukin-10 (IL-10) is an important anti-inflammatory cytokine. The polymorphisms of its promoter gene have been considered to be related with the chronicity of hepatitis B infection. OBJECTIVES:The aim of this study was to evaluate the polymorphisms at different positions in the IL-10 promoter gene in p...

journal_title：Hepatitis monthly

authors： Ghaleh Baghi S,Alavian SM,Mehrnoush L,Salimi S

更新日期：2015-07-22 00:00:00

abstract：CONTEXT:We briefly reviewed the evidence on the association of hepatitis C (HCV) infection with several aspects of mental and psychosocial health. EVIDENCE ACQUISITION:Medline was searched with appropriate keywords. The primary sources were the systematic reviews. If systematic reviews were not available for a subject...

journal_title：Hepatitis monthly

authors： Modabbernia A,Poustchi H,Malekzadeh R

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:There are limited data on the prevalence of the hepatitis B virus (HBV) infection in the agricultural population worldwide. OBJECTIVES:This study aimed to determine the prevalence of HBV infection and associated risk factors in the reproductive-age female farmworker. MATERIALS AND METHODS:This cross-sectio...

journal_title：Hepatitis monthly

authors： Yentur Doni N,Simsek Z,Keklik Z,Gurses G,Zeyrek FY

更新日期：2014-11-23 00:00:00

abstract：BACKGROUND:There is growing evidence suggesting that interleukin-18 (IL-18) plays a crucial role in viral clearance and disease pathogenesis, and that single nucleotide polymorphisms (SNPs) within the gene may influence its production. OBJECTIVES:To investigate the potential association of two polymorphisms ( 137G/C a...

journal_title：Hepatitis monthly

authors： Wu L,Chen L,Zhou L,Xie H,Wei B,Yin S,Ye Y,Fang W,Zheng S

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Reversibility of advanced fibrosis after HCV-clearance is an important goal of therapy. OBJECTIVES:Measuring liver stiffness (LS) by transient elastography (TE) might be helpful in this setting. PATIENTS AND METHODS:We evaluated 104 patients with biopsy-proven chronic hepatitis C (CHC) and sustained virolo...

journal_title：Hepatitis monthly

authors： Calvaruso V,Di Marco V,Ferraro D,Petta S,Calì A,Grazia Bavetta M,Conte E,Luigi Almasio P

更新日期：2013-05-11 00:00:00

abstract：:Patients with chronic hepatitis B infection should be followed up to identify possible changes in disease status, such as HBsAg seronversion. There are little data on the outcome of such cases, and the response rate to HBV vaccine has not been discussed extensively. ...

journal_title：Hepatitis monthly

authors： Alavian SM,Miri SM

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:In Iran, the number of injecting drug users (IDUs) has increased in recent years. The rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections among IDUs are reportedly high. OBJECTIVES:The purpose of this study was to assess factors correlated with HCV and HBV infections among IDUs in Tehran...

journal_title：Hepatitis monthly

authors： Amin-Esmaeili M,Rahimi-Movaghar A,Razaghi EM,Baghestani AR,Jafari S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In chronic liver diseases, a correct estimation of the severity of liver fibrosis is important for recommendations regarding the treatment. Nowadays, evaluation of fibrosis is done by noninvasive methods such as biochemical scores and transient elastography instead of liver biopsy. The lack of sensitivity to...

journal_title：Hepatitis monthly

authors： Sporea I,Badea R,Sirli R,Lupsor M,Popescu A,Danila M,Focsa M,Deleanu A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Patients with HBeAg-negative chronic hepatitis B (CHB) has a significantly different prognosis than inactive carriers; there is however, no reliable strategy for accurately differentiating these two disease conditions. OBJECTIVES:To determine a strategy for discriminating patients with HBeAg-negative CHB fr...

journal_title：Hepatitis monthly

authors： Kim ES,Seo YS,Keum B,Kim JH,A H,Yim HJ,Kim YS,Jeen YT,Lee HS,Chun HJ,Um SH,Duck Kim C,Ryu HS

更新日期：2011-05-01 00:00:00

abstract：UNLABELLED:CONTEXTS: Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. Because less than 20% of patients with HCC are resectable, various types of non-surgical treatment have been developed. EVIDENCE ACQUISITION:At present, radiofrequency ablation (RFA) is accepted as the standa...

journal_title：Hepatitis monthly

authors： Himoto T,Kurokohchi K,Watanabe S,Masaki T

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Zinc deficiency has been reported frequently in hepatitis C patients in the literature. Furthermore, a decrease in zinc level has been shown in beta thalassemia major as well. Iranians consume a large amount of phytate in their regimens which can bind with zinc and decrease its gastrointestinal absorption. ...

journal_title：Hepatitis monthly

authors： Abbasinazari M,Behnava B,Panahi Y,Hajhossein Talasaz A,Salimi S,Keshvari M,Mehrnoush L,Karim Elizee P,Gholami Fesharaki M,Asgharinia M,Alavian SM

更新日期：2013-08-12 00:00:00

abstract：CONTEXT:Hepatitis B vaccination of hemodialysis patients is performed all over the world. There are also recommendations from world health organizations to vaccinate patients with chronic kidney disease (CKD) prior dialysis commencement, but the implementation of a hepatitis B vaccination program is less common and not...

journal_title：Hepatitis monthly

authors： Grzegorzewska AE

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Non-invasive methods for assessment of hepatic fibrosis are increasingly needed. Recent studies showed that combined elevation of tumor markers CA 19-9 and CA 125 is predictive of severe hepatic fibrosis or cirrhosis with high specificity. OBJECTIVES:We aimed at developing a new panel of surrogate biomarker...

journal_title：Hepatitis monthly

authors： Alboraie MA,Afifi ME,Elghamry FG,Shalaby HA,Elshennawy GE,Abdelaziz AA,Shaheen MU,Abo El-Seoud AR

更新日期：2013-06-16 00:00:00

abstract：BACKGROUND:The prevalence of hepatitis C in Iran is 1% and 18% in general population and thalassemia patients respectively. The cost effectiveness analysis of adding Ribavirin to Peginterferon alfa-2a (PEG IFN alfa-2a) as a combination treatment strategy of chronic hepatitis C in thalassemia patients in comparison with...

journal_title：Hepatitis monthly

authors： Mehrazmay A,Alavian SM,Moradi-Lakeh M,Mokhtari Payam M,Hashemi-Meshkini A,Behnava B,Miri SM,Karimi Elizee P,Tabatabaee SV,Keshvari M,Bagheri Lankarani K

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:In spite of dozens of clinical trials to establish effective therapeutic and/or preventive vaccine to resolve HCV infection, no real vaccine has been proved to date. Genetic vaccines based on replication-defective adenoviruses have proved to elicit strong and long lasting T-cell responses against a number of...

journal_title：Hepatitis monthly

authors： Hosseini SY,Sabahi F,Moazzeni SM,Modarressi MH,Saberi Firoozi M,Ravanshad M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Approximately 5% of hepatitis B virus (HBV) carriers are coinfected with hepatitis D virus (HDV). HBV/HDV coinfection is a major cause of cirrhosis and end stage liver disease in chronic HBsAg carriers. The only approved therapy for chronic hepatitis delta is interferon alpha (IFN α) in either pegylated or c...

journal_title：Hepatitis monthly

authors： Keshvari M,Alavian SM,Sharafi H,Karimi G,Gholami Fesharaki M

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Cyclosporine A (CsA)-induced hepatotoxicity could be due to a reduction in α2β1 integrin expression that may either be from the direct effect of CsA itself or from reactive oxygen species (ROS) overproduction. OBJECTIVES:In this study we aimed to identify the cellular mechanisms underlying CsA-induced hepat...

journal_title：Hepatitis monthly

authors： Mostafavi-Pour Z,Khademi F,Zal F,Sardarian AR,Amini F

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:There are surprisingly a few studies that evaluate the impact of chronic viral hepatitis, which is common in HD (hemodialysis) patients, on HRQOL (health related quality of life). OBJECTIVES:We conducted a study to evaluate the impact of chronic viral hepatitis on HRQOL and to compare their HRQOL with non-i...

journal_title：Hepatitis monthly

authors： Rostami Z,Lessan Pezeshki M,Soleimani Najaf Abadi A,Einollahi B

更新日期：2013-05-30 00:00:00

abstract：BACKGROUNDS:Serum hepatitis B surface antigen (HBsAg) levels are associated with fibrosis in patients with chronic hepatitis B (CHB) infection. OBJECTIVES:The aim of our study was to evaluate serum HBsAg level as a biomarker for compensated cirrhosis in hepatitis B e antigen (HBeAg) positive CHB patients. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Jia W,Qi X,Ji YY,Xun YH,Wang H,Zhang WH,Yang JH,Wang JY,Zhu HX,Mao RC,Zhang JM

更新日期：2015-08-30 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) genotypes and mutations are gaining importance in determining the clinical course of chronic liver disease. OBJECTIVES:To determine and compare the distribution of HBV genotypes and genomic variations in Pakistan to other parts of the world. PATIENTS AND METHODS:We conducted a prosp...

journal_title：Hepatitis monthly

authors： Mumtaz K,Hamid S,Ahmed S,Moatter T,Mushtaq S,Khan A,Mizokami M,Jafri W

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:There are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (NAFLD) in different populations. However, the existing literature lacks powerful studies addressing the factors which may predict the severity of NAFLD. OBJECTIVES:In the current study, we a...

journal_title：Hepatitis monthly

authors： Ghamar-Chehreh ME,Khedmat H,Amini M,Taheri S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The entire disease spectrum of chronic HBV infection (CHB) includes asymptomatic carriers (AC), active chronic hepatitis (ACH), cirrhosis (Cir), and hepatocellular carcinoma (HCC). Previous study have demonstrated that the costimulation profiles from the livers of patients influenced immune responses and pla...

journal_title：Hepatitis monthly

authors： Yin JW,Ping Huang M,Zhong B

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:Precore stop codon (G1896A) mutation is one of the commonest mutations found in patients with chronic hepatitis B. However, over the years, this mutation was not reported much in Malaysia. OBJECTIVES:We therefore investigated the presence of G1896A mutation in Malaysian population and its association with H...

journal_title：Hepatitis monthly

authors： Suppiah J,Mohd Zain R,Bahari N,Haji Nawi S,Saat Z

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:The hepatitis B virus (HBV) antigen-induced cellular immune response plays an important role in HBV clearance. Changes in the diversity of complementarity determining region 3 (CDR3) and T-cell receptor (TCR) sequences are used to monitor the response of T cells to antigens. OBJECTIVES:The aim of the presen...

journal_title：Hepatitis monthly

authors： Xiong Y,Tan Y,Song YG

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:Hepatitis B infections, characterized by the presence of a viral genome without detectable hepatitis B surface antigen (HBsAg; Occult hepatitis B infection [OBI]), have been reported recently. OBJECTIVES:We performed serological and molecular characterization of OBI among blood donors at Jiangsu province bl...

journal_title：Hepatitis monthly

authors： Lin H,Zhao H,Tang X,Hu W,Jiang N,Zhu S,Huang C

更新日期：2016-10-02 00:00:00

abstract：INTRODUCTION:Since directly acting antivirals (DAAs) for treatment of hepatitis C virus (HCV) were introduced, conflicting data emerged about the risk of hepatocellular carcinoma (HCC) after interferon (IFN)-free treatments. We present a case of recurrent, extra-hepatic HCC in a liver-transplanted patient soon after su...

journal_title：Hepatitis monthly

authors： Strazzulla A,Iemmolo RMR,Carbone E,Postorino MC,Mazzitelli M,De Santis M,Di Benedetto F,Cristiani CM,Costa C,Pisani V,Torti C

更新日期：2016-10-30 00:00:00

abstract：:Approximately 170 million people worldwide are chronically infected by hepatitis C virus (HCV), which can result in progressive hepatic injury and fibrosis, culminating in cirrhosis and end-stage liver disease. The benchmark therapy for untreated HCV patients is a combination of pegylated interferon-alpha (PEG-IFN) an...

journal_title：Hepatitis monthly

authors： Abenavoli L,Mazza M,Almasio PL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:There have been very few studies evaluating the close association between excess iron and cirrhosis; however, cirrhosis could be regarded as an iron-loading disorder. OBJECTIVES:In this study, the goal was to show the levels of the iron content in the liver tissue in certain types of cirrhosis. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Geramizadeh B,Ghazanfari Y,Nikeghbalian S,Malekhosseini SA

更新日期：2015-12-28 00:00:00