Trends in the Burden of Hepatitis B in a Southern Brazilian State.

abstract：BACKGROUND:Non-invasive methods for assessment of hepatic fibrosis are increasingly needed. Recent studies showed that combined elevation of tumor markers CA 19-9 and CA 125 is predictive of severe hepatic fibrosis or cirrhosis with high specificity. OBJECTIVES:We aimed at developing a new panel of surrogate biomarker...

journal_title：Hepatitis monthly

authors： Alboraie MA,Afifi ME,Elghamry FG,Shalaby HA,Elshennawy GE,Abdelaziz AA,Shaheen MU,Abo El-Seoud AR

更新日期：2013-06-16 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) genotypes and mutations are gaining importance in determining the clinical course of chronic liver disease. OBJECTIVES:To determine and compare the distribution of HBV genotypes and genomic variations in Pakistan to other parts of the world. PATIENTS AND METHODS:We conducted a prosp...

journal_title：Hepatitis monthly

authors： Mumtaz K,Hamid S,Ahmed S,Moatter T,Mushtaq S,Khan A,Mizokami M,Jafri W

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:There are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (NAFLD) in different populations. However, the existing literature lacks powerful studies addressing the factors which may predict the severity of NAFLD. OBJECTIVES:In the current study, we a...

journal_title：Hepatitis monthly

authors： Ghamar-Chehreh ME,Khedmat H,Amini M,Taheri S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The prevalence of hepatitis C in Iran is 1% and 18% in general population and thalassemia patients respectively. The cost effectiveness analysis of adding Ribavirin to Peginterferon alfa-2a (PEG IFN alfa-2a) as a combination treatment strategy of chronic hepatitis C in thalassemia patients in comparison with...

journal_title：Hepatitis monthly

authors： Mehrazmay A,Alavian SM,Moradi-Lakeh M,Mokhtari Payam M,Hashemi-Meshkini A,Behnava B,Miri SM,Karimi Elizee P,Tabatabaee SV,Keshvari M,Bagheri Lankarani K

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:About 30% of individuals with hepatitis C virus (HCV) infection are able to clear HCV spontaneously. Differences in host genetics affect the outcome of HCV infection. Single nucleotide polymorphisms (SNPs) of the Interferon lambda (IFNL) genes were associated with spontaneous and treatment-induced clearance ...

journal_title：Hepatitis monthly

authors： Sharafi H,Alavian SM,Behnava B,Pouryasin A,Keshvari M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Cytokines are proteins that mediate innate and adaptive immunity responses. It is hypothesized that interferon lambda 3 (IFNL3) levels can influence the outcome of chronic hepatitis B virus (HBV) infection. Polymorphisms in IFN genes have been associated with response to infection. OBJECTIVES:This study was...

journal_title：Hepatitis monthly

authors： Heidari Z,Moudi B,Mahmoudzadeh-Sagheb H,Hashemi M

更新日期：2016-03-05 00:00:00

abstract：BACKGROUND:In chronic liver diseases, a correct estimation of the severity of liver fibrosis is important for recommendations regarding the treatment. Nowadays, evaluation of fibrosis is done by noninvasive methods such as biochemical scores and transient elastography instead of liver biopsy. The lack of sensitivity to...

journal_title：Hepatitis monthly

authors： Sporea I,Badea R,Sirli R,Lupsor M,Popescu A,Danila M,Focsa M,Deleanu A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Hepatitis B infections, characterized by the presence of a viral genome without detectable hepatitis B surface antigen (HBsAg; Occult hepatitis B infection [OBI]), have been reported recently. OBJECTIVES:We performed serological and molecular characterization of OBI among blood donors at Jiangsu province bl...

journal_title：Hepatitis monthly

authors： Lin H,Zhao H,Tang X,Hu W,Jiang N,Zhu S,Huang C

更新日期：2016-10-02 00:00:00

abstract：BACKGROUND:Hepatitis A, a fecal-oral transmitted disease, which has been considered endemic in developing countries, seems to change its pattern in developing countries because of their improved socioeconomic status. OBJECTIVES:In the present study, we aimed to determine the need of vaccination in 270 students at AJA ...

journal_title：Hepatitis monthly

authors： Hosseini Shokouh SJ,Dadashi A,Abiri M,Zohrevand I,Eshraghian A,Khoshdel A,Heidari B,Khoshkish S

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:A functional cure of chronic hepatitis B (CHB) is feasible, but a clear view of the intrahepatic viral dynamics in each patient is needed. Intrahepatic covalently closed circular DNA (cccDNA) is the stable form of the viral genome in infected cells, and represents the ideal marker of parenchymal colonization...

journal_title：Hepatitis monthly

authors： Minosse C,Coen S,Visco Comandini U,Lionetti R,Montalbano M,Cerilli S,Vincenti D,Baiocchini A,Capobianchi MR,Menzo S

更新日期：2016-02-29 00:00:00

abstract：BACKGROUND:During antiviral therapy for chronic hepatitis B, renal function impairment could be a critical concern when oral nucleot(s)ide analogues were used. Paradoxically, long-term telbivudine treatment was associated with an increase of estimated glomerular filtration rate (eGFR) through unknown mechanisms. OBJEC...

journal_title：Hepatitis monthly

authors： Liang KH,Chen YC,Hsu CW,Chang ML,Yeh CT

更新日期：2014-01-31 00:00:00

abstract：:Patients with chronic hepatitis B infection should be followed up to identify possible changes in disease status, such as HBsAg seronversion. There are little data on the outcome of such cases, and the response rate to HBV vaccine has not been discussed extensively. ...

journal_title：Hepatitis monthly

authors： Alavian SM,Miri SM

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Human leukocyte antigen (HLA) typing in autoimmune hepatitis (AIH) has been investigated in different populations and ethnic groups, but no such data is available from Pakistan. OBJECTIVES:The aim of this study was to evaluate the clinical profile of autoimmune hepatitis (AIH), and determine the associated ...

journal_title：Hepatitis monthly

authors： Hassan N,Siddiqui AR,Abbas Z,Hassan SM,Soomro GB,Mubarak M,Anis S,Muzaffar R,Zafar MN

更新日期：2013-12-16 00:00:00

abstract：CONTEXT:The hepatitis C virus (HCV) is classified into seven genotypes and more than 100 subtypes. The treatment regimen, duration and efficacy of HCV therapy may vary according to the HCV genotype. Therefore, the HCV genotype should be determined prior to antiviral therapy. The objective of the current study was to re...

journal_title：Hepatitis monthly

authors： Ghaderi-Zefrehi H,Gholami-Fesharaki M,Sharafi H,Sadeghi F,Alavian SM

更新日期：2016-08-23 00:00:00

abstract：BACKGROUND:While Roux-en-Y hepaticojejunostomy (RYH) is the common anastomotic technique for liver transplantation (LT) in patients with primary sclerosing cholangitis (PSC), duct-to-duct (DD) reconstruction may be used if the recipient common bile duct is normal. There are conflicting observational data on the rate of...

journal_title：Hepatitis monthly

authors： Al-Judaibi B,Hernandez Alejandro R,Uhanova J,Marotta P,Mosli M,Chandok N

更新日期：2015-05-23 00:00:00

abstract：BACKGROUND:Precore stop codon (G1896A) mutation is one of the commonest mutations found in patients with chronic hepatitis B. However, over the years, this mutation was not reported much in Malaysia. OBJECTIVES:We therefore investigated the presence of G1896A mutation in Malaysian population and its association with H...

journal_title：Hepatitis monthly

authors： Suppiah J,Mohd Zain R,Bahari N,Haji Nawi S,Saat Z

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND AND AIMS:The duration of the protection of hepatitis B vaccination for infants and the necessity of a booster dose administration is unknown. The aim of the present study was to evaluate the persistence of seroprotection after hepatitis B virus (HBV) vaccination in order to determine the necessity of a singl...

journal_title：Hepatitis monthly

authors： Yazdanpanah B,Safari M,Yazdanpanah S

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Liver storage diseases are rare biochemical and inherited diseases that affect multiorgan systems. OBJECTIVES:This study was performed to determine the rate of storage diseases and their types in liver pathology specimens of subjects who were referred to a tertiary pediatric center. PATIENTS AND METHODS:Tw...

journal_title：Hepatitis monthly

authors： Motamed F,Monajemzadeh M,Seifirad S,Ashrafi M,Rasti A,Mahjoub F

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:There are surprisingly a few studies that evaluate the impact of chronic viral hepatitis, which is common in HD (hemodialysis) patients, on HRQOL (health related quality of life). OBJECTIVES:We conducted a study to evaluate the impact of chronic viral hepatitis on HRQOL and to compare their HRQOL with non-i...

journal_title：Hepatitis monthly

authors： Rostami Z,Lessan Pezeshki M,Soleimani Najaf Abadi A,Einollahi B

更新日期：2013-05-30 00:00:00

abstract：BACKGROUNDS:Serum hepatitis B surface antigen (HBsAg) levels are associated with fibrosis in patients with chronic hepatitis B (CHB) infection. OBJECTIVES:The aim of our study was to evaluate serum HBsAg level as a biomarker for compensated cirrhosis in hepatitis B e antigen (HBeAg) positive CHB patients. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Jia W,Qi X,Ji YY,Xun YH,Wang H,Zhang WH,Yang JH,Wang JY,Zhu HX,Mao RC,Zhang JM

更新日期：2015-08-30 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection as a worldwide health problem is associated with cirrhosis and hepatocellular carcinoma. With current treatment regimen, pegylated interferon (PEG-IFN) plus ribavirin, sustain virological response (SVR) is achieved in only 50% of infected individuals. In HCV infection, an in...

journal_title：Hepatitis monthly

authors： Sarvari J,Norozian H,Fattahi MR,Pirbonyeh N,Moattari A

更新日期：2014-01-23 00:00:00

abstract：BACKGROUND AND AIMS:The treatment of chronic hepatitis B (CHB) is a challenging problem today, and previous study has shown that oxidative stress causes the collective pathophysiological conditions of many hepatopathies, so other new therapeutic approaches are needed. Hence, in this study the paraclinical and oxidative...

journal_title：Hepatitis monthly

authors： Shohrati M,Dermanaki F,Babaei F,Alavian SM

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Interleukin-10 (IL-10) is an important anti-inflammatory cytokine. The polymorphisms of its promoter gene have been considered to be related with the chronicity of hepatitis B infection. OBJECTIVES:The aim of this study was to evaluate the polymorphisms at different positions in the IL-10 promoter gene in p...

journal_title：Hepatitis monthly

authors： Ghaleh Baghi S,Alavian SM,Mehrnoush L,Salimi S

更新日期：2015-07-22 00:00:00

abstract：BACKGROUND:Good knowledge, attitude and practice (KAP) of the physicians allow them to handle their patients in such a way that they prevent themselves from contracting, and their patients from spreading, the infection. However, the Iranian standardized KAP questionnaire of physicians about viral hepatitis is not avail...

journal_title：Hepatitis monthly

authors： Ghasemi S,Kabir A,Ansari Jafari M,Jalali M,Amini A,Faghihi-Kashani AH,Alavian SM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Nearly 0.5% of Iranians are infected with HCV. Peginterferon-alpha-2a and Peginterferon-alpha-2b are the two available types of interferon for the treatment of hepatitis C. Comparing the results of these two treatments is still a challenge. OBJECTIVES:The aim of this study was to compare the results of Pegi...

journal_title：Hepatitis monthly

authors： Pouresmaeeli M,Alavian SM,Keshvari M,Salimi S,Mehrnoush L

更新日期：2015-09-29 00:00:00

abstract：BACKGROUND:The prevalence of newly-diagnosed cases of chronic hepatitis is decisive for the overall incidence rate of hepatitis B observed in Poland. OBJECTIVES:We aimed to determine the chronic hepatitis B incidence trends in Poland, taking into consideration the ages, genders, and environments of the patients. METH...

journal_title：Hepatitis monthly

authors： Stawinska-Witoszynska B,Zysnarska M,Krzywinska-Wiewiorowska M,Wojtyła-Buciorab P,Krzyzaniak A,Wieckowska B

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Despite improvement in hepatitis B infection prevention through national vaccination programs, implementation of compulsory and thorough blood donor screening, and reduction of transfusion numbers due to erythropoietin administration,hepatitis B remains a major concern in hemodialysis (HD) centers [1]. Compa...

journal_title：Hepatitis monthly

authors： Hashemi B,Mahdavi-Mazdeh M,Abbasi M,Hosseini-Moghaddam SM,Zinat NH,Ahmadi F

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Hepatitis B is a common infectious disease in China. Many studies have shown that the genotype of hepatitis B virus (HBV) is probably associated with the efficacy of some antiviral drugs such as interferon α (IFN-α) and Lamivudine (LAM). However, the association between HBV genotype and adefovir dipivoxil (A...

journal_title：Hepatitis monthly

authors： Wen Z,Zhang H,Zhang M,Tan D,Li Q,Zhang H,Wu P,Deng L

更新日期：2014-08-17 00:00:00

abstract：BACKGROUND:In Iran, the number of injecting drug users (IDUs) has increased in recent years. The rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections among IDUs are reportedly high. OBJECTIVES:The purpose of this study was to assess factors correlated with HCV and HBV infections among IDUs in Tehran...

journal_title：Hepatitis monthly

authors： Amin-Esmaeili M,Rahimi-Movaghar A,Razaghi EM,Baghestani AR,Jafari S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Cyclosporine A (CsA)-induced hepatotoxicity could be due to a reduction in α2β1 integrin expression that may either be from the direct effect of CsA itself or from reactive oxygen species (ROS) overproduction. OBJECTIVES:In this study we aimed to identify the cellular mechanisms underlying CsA-induced hepat...

journal_title：Hepatitis monthly

authors： Mostafavi-Pour Z,Khademi F,Zal F,Sardarian AR,Amini F

更新日期：2013-08-13 00:00:00