Efficacy and Tolerability of Peginterferon alpha-2a and Peginterferon alpha-2b in Iranian Patients With Chronic Hepatitis C.

abstract：BACKGROUND:Good knowledge, attitude and practice (KAP) of the physicians allow them to handle their patients in such a way that they prevent themselves from contracting, and their patients from spreading, the infection. However, the Iranian standardized KAP questionnaire of physicians about viral hepatitis is not avail...

journal_title：Hepatitis monthly

authors： Ghasemi S,Kabir A,Ansari Jafari M,Jalali M,Amini A,Faghihi-Kashani AH,Alavian SM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV), hepatitis D virus (HDV), and human immunodeficiency virus (HIV) are transmitted by blood transfusion. Thus, hemodialysis (HD) patients are more prone to become the carriers of these infections due to their treatment demands. OBJECTIVES:The aim of this study was to assess the prevale...

journal_title：Hepatitis monthly

authors： Bahri F,Kargar Kheirabad A,Ghasemzadeh I,Shoja S,Gouklani H

更新日期：2016-01-23 00:00:00

abstract：BACKGROUND:Non-invasive methods for assessment of hepatic fibrosis are increasingly needed. Recent studies showed that combined elevation of tumor markers CA 19-9 and CA 125 is predictive of severe hepatic fibrosis or cirrhosis with high specificity. OBJECTIVES:We aimed at developing a new panel of surrogate biomarker...

journal_title：Hepatitis monthly

authors： Alboraie MA,Afifi ME,Elghamry FG,Shalaby HA,Elshennawy GE,Abdelaziz AA,Shaheen MU,Abo El-Seoud AR

更新日期：2013-06-16 00:00:00

abstract：BACKGROUND:Genetic polymorphisms may play role in the pathophysiology of nonalcoholic steatohepatitis (NASH). OBJECTIVES:We purposed to assess the role of interleukin 6 (IL 6) and interleukin 8 (IL 8) gene polymorphisms in the pathogenesis of NASH. PATIENTS AND METHODS:Consecutive patients with biopsy proven NASH and...

journal_title：Hepatitis monthly

authors： Cengiz M,Yasar DG,Ergun MA,Akyol G,Ozenirler S

更新日期：2014-12-24 00:00:00

abstract：:Hepatitis C virus (HCV) infection is increasingly recognized as a major health care problem, and is found frequently in Pakistani settings. In this article we reviewed published and unpublished data related to the seroepidemiology of HCV infection in Pakistan. For this article, data from 132 published studies and thre...

journal_title：Hepatitis monthly

authors： Umar M,Bushra HT,Ahmad M,Data A,Ahmad M,Khurram M,Usman S,Arif M,Adam T,Minhas Z,Arif A,Naeem A,Ejaz K,Butt Z,Bilal M

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Due to the high efficacy of combination antiretroviral therapy (cART), the number of patients living with HIV is increasing. Chronic HCV infection has become a leading cause of non-AIDS related morbidity and mortality in patients with HIV infection. OBJECTIVES:The aim of this cross-sectional study was to id...

journal_title：Hepatitis monthly

authors： Brescini L,Orsetti E,Gesuita R,Piraccini F,Marchionni E,Staffolani S,Castelli P,Drenaggi D,Barchiesi F

更新日期：2014-08-05 00:00:00

abstract：BACKGROUND:Global prevalence of Hepatitis C Virus (HCV) infection corresponds to about 130 million HCV positive patients worldwide. The only drug that effectively reduces viral load is interferon-α (IFN-α) and currently combination of IFN and ribavirin is the choice for treatment. OBJECTIVES:The present study is aimed...

journal_title：Hepatitis monthly

authors： Kanwal S,Mahmood T

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:In spite of dozens of clinical trials to establish effective therapeutic and/or preventive vaccine to resolve HCV infection, no real vaccine has been proved to date. Genetic vaccines based on replication-defective adenoviruses have proved to elicit strong and long lasting T-cell responses against a number of...

journal_title：Hepatitis monthly

authors： Hosseini SY,Sabahi F,Moazzeni SM,Modarressi MH,Saberi Firoozi M,Ravanshad M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:There are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (NAFLD) in different populations. However, the existing literature lacks powerful studies addressing the factors which may predict the severity of NAFLD. OBJECTIVES:In the current study, we a...

journal_title：Hepatitis monthly

authors： Ghamar-Chehreh ME,Khedmat H,Amini M,Taheri S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:GB virus C (GBV-C) or hepatitis G virus (HGV) is a newly discovered and enveloped RNA positive-stranded flavivirus-like particle, which has not yet been proven to have major negative effects on liver. OBJECTIVES:Increasing the risk of blood-borne infections in hemodialysis patients is a main health care con...

journal_title：Hepatitis monthly

authors： Dadmanesh M,Hosseinzadeh M,Keyvani H,Ghorban K,Rahimi M,Hosseinzadeh M,Ranjbar MM

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Current guidelines introduce periodic monitoring of serum alanine transaminase (ALT) as the first-line modality in follow-up patients, with a hepatitis B virus (HBV) inactive carrier state. OBJECTIVES:This study aimed to determine the incidence rate and patterns of ALT fluctuations and prognostic values for...

journal_title：Hepatitis monthly

authors： Farzi H,Ebrahimi Daryani N,Mehrnoush L,Salimi S,Alavian SM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:There are surprisingly a few studies that evaluate the impact of chronic viral hepatitis, which is common in HD (hemodialysis) patients, on HRQOL (health related quality of life). OBJECTIVES:We conducted a study to evaluate the impact of chronic viral hepatitis on HRQOL and to compare their HRQOL with non-i...

journal_title：Hepatitis monthly

authors： Rostami Z,Lessan Pezeshki M,Soleimani Najaf Abadi A,Einollahi B

更新日期：2013-05-30 00:00:00

abstract：BACKGROUND:In Iran, the number of injecting drug users (IDUs) has increased in recent years. The rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections among IDUs are reportedly high. OBJECTIVES:The purpose of this study was to assess factors correlated with HCV and HBV infections among IDUs in Tehran...

journal_title：Hepatitis monthly

authors： Amin-Esmaeili M,Rahimi-Movaghar A,Razaghi EM,Baghestani AR,Jafari S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Hepatitis A, a fecal-oral transmitted disease, which has been considered endemic in developing countries, seems to change its pattern in developing countries because of their improved socioeconomic status. OBJECTIVES:In the present study, we aimed to determine the need of vaccination in 270 students at AJA ...

journal_title：Hepatitis monthly

authors： Hosseini Shokouh SJ,Dadashi A,Abiri M,Zohrevand I,Eshraghian A,Khoshdel A,Heidari B,Khoshkish S

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) genotypes and mutations are gaining importance in determining the clinical course of chronic liver disease. OBJECTIVES:To determine and compare the distribution of HBV genotypes and genomic variations in Pakistan to other parts of the world. PATIENTS AND METHODS:We conducted a prosp...

journal_title：Hepatitis monthly

authors： Mumtaz K,Hamid S,Ahmed S,Moatter T,Mushtaq S,Khan A,Mizokami M,Jafri W

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:During antiviral therapy for chronic hepatitis B, renal function impairment could be a critical concern when oral nucleot(s)ide analogues were used. Paradoxically, long-term telbivudine treatment was associated with an increase of estimated glomerular filtration rate (eGFR) through unknown mechanisms. OBJEC...

journal_title：Hepatitis monthly

authors： Liang KH,Chen YC,Hsu CW,Chang ML,Yeh CT

更新日期：2014-01-31 00:00:00

abstract：BACKGROUND:Liver storage diseases are rare biochemical and inherited diseases that affect multiorgan systems. OBJECTIVES:This study was performed to determine the rate of storage diseases and their types in liver pathology specimens of subjects who were referred to a tertiary pediatric center. PATIENTS AND METHODS:Tw...

journal_title：Hepatitis monthly

authors： Motamed F,Monajemzadeh M,Seifirad S,Ashrafi M,Rasti A,Mahjoub F

更新日期：2011-08-01 00:00:00

abstract：:Approximately 170 million people worldwide are chronically infected by hepatitis C virus (HCV), which can result in progressive hepatic injury and fibrosis, culminating in cirrhosis and end-stage liver disease. The benchmark therapy for untreated HCV patients is a combination of pegylated interferon-alpha (PEG-IFN) an...

journal_title：Hepatitis monthly

authors： Abenavoli L,Mazza M,Almasio PL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Despite improvement in hepatitis B infection prevention through national vaccination programs, implementation of compulsory and thorough blood donor screening, and reduction of transfusion numbers due to erythropoietin administration,hepatitis B remains a major concern in hemodialysis (HD) centers [1]. Compa...

journal_title：Hepatitis monthly

authors： Hashemi B,Mahdavi-Mazdeh M,Abbasi M,Hosseini-Moghaddam SM,Zinat NH,Ahmadi F

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The duration of the protection of hepatitis B vaccination for infants and the necessity of a booster dose administration is unknown. The aim of the present study was to evaluate the persistence of seroprotection after hepatitis B virus (HBV) vaccination in order to determine the necessity of a singl...

journal_title：Hepatitis monthly

authors： Yazdanpanah B,Safari M,Yazdanpanah S

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The hepatitis B virus (HBV) antigen-induced cellular immune response plays an important role in HBV clearance. Changes in the diversity of complementarity determining region 3 (CDR3) and T-cell receptor (TCR) sequences are used to monitor the response of T cells to antigens. OBJECTIVES:The aim of the presen...

journal_title：Hepatitis monthly

authors： Xiong Y,Tan Y,Song YG

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:Hepatitis viruses are one of the most important concerns in the patients on hemodialysis who are at high risk for blood-borne infections. GB virus C (GBV-C)/hepatitis G virus (HGV) is positive-stranded RNA virus with global distribution, which codes structural and nonstructural proteins (such as NS3). OBJEC...

journal_title：Hepatitis monthly

authors： Dadmanesh M,Ranjbar MM,Alavian SM,Ghorban K

更新日期：2015-03-05 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection as a worldwide health problem is associated with cirrhosis and hepatocellular carcinoma. With current treatment regimen, pegylated interferon (PEG-IFN) plus ribavirin, sustain virological response (SVR) is achieved in only 50% of infected individuals. In HCV infection, an in...

journal_title：Hepatitis monthly

authors： Sarvari J,Norozian H,Fattahi MR,Pirbonyeh N,Moattari A

更新日期：2014-01-23 00:00:00

abstract：UNLABELLED:CONTEXTS: Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. Because less than 20% of patients with HCC are resectable, various types of non-surgical treatment have been developed. EVIDENCE ACQUISITION:At present, radiofrequency ablation (RFA) is accepted as the standa...

journal_title：Hepatitis monthly

authors： Himoto T,Kurokohchi K,Watanabe S,Masaki T

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The prevalence of newly-diagnosed cases of chronic hepatitis is decisive for the overall incidence rate of hepatitis B observed in Poland. OBJECTIVES:We aimed to determine the chronic hepatitis B incidence trends in Poland, taking into consideration the ages, genders, and environments of the patients. METH...

journal_title：Hepatitis monthly

authors： Stawinska-Witoszynska B,Zysnarska M,Krzywinska-Wiewiorowska M,Wojtyła-Buciorab P,Krzyzaniak A,Wieckowska B

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Cyclosporine A (CsA)-induced hepatotoxicity could be due to a reduction in α2β1 integrin expression that may either be from the direct effect of CsA itself or from reactive oxygen species (ROS) overproduction. OBJECTIVES:In this study we aimed to identify the cellular mechanisms underlying CsA-induced hepat...

journal_title：Hepatitis monthly

authors： Mostafavi-Pour Z,Khademi F,Zal F,Sardarian AR,Amini F

更新日期：2013-08-13 00:00:00

abstract：CONTEXT:The hepatitis C virus (HCV) is classified into seven genotypes and more than 100 subtypes. The treatment regimen, duration and efficacy of HCV therapy may vary according to the HCV genotype. Therefore, the HCV genotype should be determined prior to antiviral therapy. The objective of the current study was to re...

journal_title：Hepatitis monthly

authors： Ghaderi-Zefrehi H,Gholami-Fesharaki M,Sharafi H,Sadeghi F,Alavian SM

更新日期：2016-08-23 00:00:00

abstract：BACKGROUND:In chronic liver diseases, a correct estimation of the severity of liver fibrosis is important for recommendations regarding the treatment. Nowadays, evaluation of fibrosis is done by noninvasive methods such as biochemical scores and transient elastography instead of liver biopsy. The lack of sensitivity to...

journal_title：Hepatitis monthly

authors： Sporea I,Badea R,Sirli R,Lupsor M,Popescu A,Danila M,Focsa M,Deleanu A

更新日期：2011-07-01 00:00:00

abstract：CONTEXT:We briefly reviewed the evidence on the association of hepatitis C (HCV) infection with several aspects of mental and psychosocial health. EVIDENCE ACQUISITION:Medline was searched with appropriate keywords. The primary sources were the systematic reviews. If systematic reviews were not available for a subject...

journal_title：Hepatitis monthly

authors： Modabbernia A,Poustchi H,Malekzadeh R

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Hemophilic patients require long-life intravenous infusion of factor concentrates to treat bleedings. This could increase the risk of transmission of blood-borne infections like hepatitis C. OBJECTIVES:The current study was aimed at investigating the immunity status against hepatitis A in hemophilic patient...

journal_title：Hepatitis monthly

authors： Mirzaei J,Ziaee M,Farsad SA,Fereydooni M,Anani Sarab G,Rezvani Khorashad MR

更新日期：2016-04-05 00:00:00