Recent advances in radiofrequency ablation for the management of hepatocellular carcinoma.

Abstract:

UNLABELLED:CONTEXTS: Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. Because less than 20% of patients with HCC are resectable, various types of non-surgical treatment have been developed. EVIDENCE ACQUISITION:At present, radiofrequency ablation (RFA) is accepted as the standard local treatment for patients with HCC because of its superior local control and overall survival compared to other local treatments. RESULTS:New devices for RFA and combination treatments of RFA with other procedures have been developed to improve anti-tumoral effects. CONCLUSIONS:This review mainly focuses on the status of RFA in the management of HCC and recent advances in RFA treatment technology.

journal_name

Hepat Mon

journal_title

Hepatitis monthly

authors

Himoto T,Kurokohchi K,Watanabe S,Masaki T

doi

10.5812/hepatmon.5945

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

e5945

issue

10 HCC

eissn

1735-143X

issn

1735-3408

journal_volume

12

pub_type

杂志文章
  • A Single Center Study Comparing the Stainable Iron Depositions in 1000 Explanted Cirrhotic Livers of Different Causes.

    abstract:BACKGROUND:There have been very few studies evaluating the close association between excess iron and cirrhosis; however, cirrhosis could be regarded as an iron-loading disorder. OBJECTIVES:In this study, the goal was to show the levels of the iron content in the liver tissue in certain types of cirrhosis. PATIENTS AN...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.33710

    authors: Geramizadeh B,Ghazanfari Y,Nikeghbalian S,Malekhosseini SA

    更新日期:2015-12-28 00:00:00

  • The role of interleukin-6 and interleukin-8 gene polymorphisms in non-alcoholic steatohepatitis.

    abstract:BACKGROUND:Genetic polymorphisms may play role in the pathophysiology of nonalcoholic steatohepatitis (NASH). OBJECTIVES:We purposed to assess the role of interleukin 6 (IL 6) and interleukin 8 (IL 8) gene polymorphisms in the pathogenesis of NASH. PATIENTS AND METHODS:Consecutive patients with biopsy proven NASH and...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.24635

    authors: Cengiz M,Yasar DG,Ergun MA,Akyol G,Ozenirler S

    更新日期:2014-12-24 00:00:00

  • The Role of Interferon Gamma Gene Polymorphism (+874A/T, +2109A/G, and -183G/T) in Response to Treatment Among Hepatitis C Infected Patients in Fars Province, Southern Iran.

    abstract:BACKGROUND:Hepatitis C virus (HCV) infection as a worldwide health problem is associated with cirrhosis and hepatocellular carcinoma. With current treatment regimen, pegylated interferon (PEG-IFN) plus ribavirin, sustain virological response (SVR) is achieved in only 50% of infected individuals. In HCV infection, an in...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.14476

    authors: Sarvari J,Norozian H,Fattahi MR,Pirbonyeh N,Moattari A

    更新日期:2014-01-23 00:00:00

  • Neuropsychiatric and psychosocial issues of patients with hepatitis C infection: a selective literature review.

    abstract:CONTEXT:We briefly reviewed the evidence on the association of hepatitis C (HCV) infection with several aspects of mental and psychosocial health. EVIDENCE ACQUISITION:Medline was searched with appropriate keywords. The primary sources were the systematic reviews. If systematic reviews were not available for a subject...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.8340

    authors: Modabbernia A,Poustchi H,Malekzadeh R

    更新日期:2013-01-01 00:00:00

  • Vaccine-Induced Anti-HBs Level in 5-6 Year-Old Malnourished Children.

    abstract:BACKGROUND:Malnutrition is the most common cause of immune deficiency. It results in reduced secretion of T-cells and B-cell-stimulating factors leading to declining of special immunoglobulins. On the other hand, hepatitis B, as a major world health problem, can be prevented effectively by vaccination. Three doses of h...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.7048

    authors: Karimi M,Raee A,Baghianimoghadam B,Fallahzadeh MH

    更新日期:2013-02-03 00:00:00

  • Construction and preparation of three recombinant adenoviruses expressing truncated NS3 and core genes of hepatitis C virus for vaccine purposes.

    abstract:BACKGROUND:In spite of dozens of clinical trials to establish effective therapeutic and/or preventive vaccine to resolve HCV infection, no real vaccine has been proved to date. Genetic vaccines based on replication-defective adenoviruses have proved to elicit strong and long lasting T-cell responses against a number of...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.6130

    authors: Hosseini SY,Sabahi F,Moazzeni SM,Modarressi MH,Saberi Firoozi M,Ravanshad M

    更新日期:2012-08-01 00:00:00

  • The role of anesthetic drugs in liver apoptosis.

    abstract:CONTEXT:The modern practice of anesthesia is highly dependent ona group of anesthetic drugs which many of them are metabolized in the liver. EVIDENCE ACQUISITION:The liver, of course, usually tolerates this burden. However, this is not always an unbroken rule. Anesthetic induced apoptosis has gained great concern duri...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章,评审

    doi:10.5812/hepatmon.13162

    authors: Dabbagh A,Rajaei S

    更新日期:2013-08-25 00:00:00

  • Prognostic values of fluctuations in serum levels of alanine transaminase in inactive carrier state of HBV infection.

    abstract:BACKGROUND:Current guidelines introduce periodic monitoring of serum alanine transaminase (ALT) as the first-line modality in follow-up patients, with a hepatitis B virus (HBV) inactive carrier state. OBJECTIVES:This study aimed to determine the incidence rate and patterns of ALT fluctuations and prognostic values for...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.17537

    authors: Farzi H,Ebrahimi Daryani N,Mehrnoush L,Salimi S,Alavian SM

    更新日期:2014-05-01 00:00:00

  • Impact of the IL-10 Promoter Gene Polymorphisms in the Severity of Chronic Hepatitis B Infection.

    abstract:BACKGROUND:Interleukin-10 (IL-10) is an important anti-inflammatory cytokine. The polymorphisms of its promoter gene have been considered to be related with the chronicity of hepatitis B infection. OBJECTIVES:The aim of this study was to evaluate the polymorphisms at different positions in the IL-10 promoter gene in p...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.28287v2

    authors: Ghaleh Baghi S,Alavian SM,Mehrnoush L,Salimi S

    更新日期:2015-07-22 00:00:00

  • Liver storage disease in Iran: a ten year study of liver biopsies in Children Medical Center Hospital in Tehran-Iran.

    abstract:BACKGROUND:Liver storage diseases are rare biochemical and inherited diseases that affect multiorgan systems. OBJECTIVES:This study was performed to determine the rate of storage diseases and their types in liver pathology specimens of subjects who were referred to a tertiary pediatric center. PATIENTS AND METHODS:Tw...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/kowsar.1735143x.718

    authors: Motamed F,Monajemzadeh M,Seifirad S,Ashrafi M,Rasti A,Mahjoub F

    更新日期:2011-08-01 00:00:00

  • Association of interleukin 18 gene promoter polymorphisms with HBV recurrence after liver transplantation in Han Chinese population.

    abstract:BACKGROUND:There is growing evidence suggesting that interleukin-18 (IL-18) plays a crucial role in viral clearance and disease pathogenesis, and that single nucleotide polymorphisms (SNPs) within the gene may influence its production. OBJECTIVES:To investigate the potential association of two polymorphisms ( 137G/C a...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:

    authors: Wu L,Chen L,Zhou L,Xie H,Wei B,Yin S,Ye Y,Fang W,Zheng S

    更新日期:2011-06-01 00:00:00

  • Clinical Profile and HLA Typing of Autoimmune Hepatitis From Pakistan.

    abstract:BACKGROUND:Human leukocyte antigen (HLA) typing in autoimmune hepatitis (AIH) has been investigated in different populations and ethnic groups, but no such data is available from Pakistan. OBJECTIVES:The aim of this study was to evaluate the clinical profile of autoimmune hepatitis (AIH), and determine the associated ...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.13598

    authors: Hassan N,Siddiqui AR,Abbas Z,Hassan SM,Soomro GB,Mubarak M,Anis S,Muzaffar R,Zafar MN

    更新日期:2013-12-16 00:00:00

  • Intrahepatic Toll-Like Receptor 3 in Chronic HBV Infection Subjects: Asymptomatic Carriers, Active Chronic Hepatitis, Cirrhosis, and Hepatocellular Carcinoma.

    abstract:BACKGROUND:The entire disease spectrum of chronic HBV infection (CHB) includes asymptomatic carriers (AC), active chronic hepatitis (ACH), cirrhosis (Cir), and hepatocellular carcinoma (HCC). Previous study have demonstrated that the costimulation profiles from the livers of patients influenced immune responses and pla...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.34432

    authors: Yin JW,Ping Huang M,Zhong B

    更新日期:2016-05-23 00:00:00

  • Epidemiology of hepatitis B in the reproductive-age female farmworkers of southeastern Turkey.

    abstract:BACKGROUND:There are limited data on the prevalence of the hepatitis B virus (HBV) infection in the agricultural population worldwide. OBJECTIVES:This study aimed to determine the prevalence of HBV infection and associated risk factors in the reproductive-age female farmworker. MATERIALS AND METHODS:This cross-sectio...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.22120

    authors: Yentur Doni N,Simsek Z,Keklik Z,Gurses G,Zeyrek FY

    更新日期:2014-11-23 00:00:00

  • The optimal dose of ribavirin for chronic hepatitis C: From literature evidence to clinical practice: The optimal dose of ribavirin for chronic hepatitis C.

    abstract::Approximately 170 million people worldwide are chronically infected by hepatitis C virus (HCV), which can result in progressive hepatic injury and fibrosis, culminating in cirrhosis and end-stage liver disease. The benchmark therapy for untreated HCV patients is a combination of pegylated interferon-alpha (PEG-IFN) an...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:

    authors: Abenavoli L,Mazza M,Almasio PL

    更新日期:2011-04-01 00:00:00

  • Evaluating Liver Fibrosis by Transient Elastometry in Patients With HIV-HCV Coinfection and Monoinfection.

    abstract:BACKGROUND:Due to the high efficacy of combination antiretroviral therapy (cART), the number of patients living with HIV is increasing. Chronic HCV infection has become a leading cause of non-AIDS related morbidity and mortality in patients with HIV infection. OBJECTIVES:The aim of this cross-sectional study was to id...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.15426

    authors: Brescini L,Orsetti E,Gesuita R,Piraccini F,Marchionni E,Staffolani S,Castelli P,Drenaggi D,Barchiesi F

    更新日期:2014-08-05 00:00:00

  • Assessment of noninvasive liver stiffness in inactive HBsAg carriers by transient elastography: Fibroscan in inactive HBsAg carriers.

    abstract:BACKGROUND:Chronic viral hepatitis can be evaluated using invasive or noninvasive methods. OBJECTIVES:The aim of this study was to evaluate liver stiffness in inactive HBsAg carriers compared with normal subjects and determine if it is influenced by viral load in these patients. PATIENTS AND METHODS:We prospectively ...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:

    authors: Sporea I,Nicolita D,Sirli R,Deleanu A,Tudora A,Bota S

    更新日期:2011-03-01 00:00:00

  • G1896A Precore Mutation and Association With HBeAg Status, Genotype and Clinical Status in Patients With Chronic Hepatitis B.

    abstract:BACKGROUND:Precore stop codon (G1896A) mutation is one of the commonest mutations found in patients with chronic hepatitis B. However, over the years, this mutation was not reported much in Malaysia. OBJECTIVES:We therefore investigated the presence of G1896A mutation in Malaysian population and its association with H...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.31490

    authors: Suppiah J,Mohd Zain R,Bahari N,Haji Nawi S,Saat Z

    更新日期:2015-10-28 00:00:00

  • The Distribution of Hepatitis C Virus Genotypes in Middle Eastern Countries: A Systematic Review and Meta-Analysis.

    abstract:CONTEXT:The hepatitis C virus (HCV) is classified into seven genotypes and more than 100 subtypes. The treatment regimen, duration and efficacy of HCV therapy may vary according to the HCV genotype. Therefore, the HCV genotype should be determined prior to antiviral therapy. The objective of the current study was to re...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章,评审

    doi:10.5812/hepatmon.40357

    authors: Ghaderi-Zefrehi H,Gholami-Fesharaki M,Sharafi H,Sadeghi F,Alavian SM

    更新日期:2016-08-23 00:00:00

  • Effect of hepatitis B virus genotypes on the efficacy of adefovir dipivoxil antiviral therapy.

    abstract:BACKGROUND:Hepatitis B is a common infectious disease in China. Many studies have shown that the genotype of hepatitis B virus (HBV) is probably associated with the efficacy of some antiviral drugs such as interferon α (IFN-α) and Lamivudine (LAM). However, the association between HBV genotype and adefovir dipivoxil (A...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.10813

    authors: Wen Z,Zhang H,Zhang M,Tan D,Li Q,Zhang H,Wu P,Deng L

    更新日期:2014-08-17 00:00:00

  • Vaccination Against Hepatitis A for Hemophilic Patients: Is It Necessary?

    abstract:BACKGROUND:Hemophilic patients require long-life intravenous infusion of factor concentrates to treat bleedings. This could increase the risk of transmission of blood-borne infections like hepatitis C. OBJECTIVES:The current study was aimed at investigating the immunity status against hepatitis A in hemophilic patient...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.37447

    authors: Mirzaei J,Ziaee M,Farsad SA,Fereydooni M,Anani Sarab G,Rezvani Khorashad MR

    更新日期:2016-04-05 00:00:00

  • Trends in the Burden of Hepatitis B in a Southern Brazilian State.

    abstract:BACKGROUND:Viral hepatitis is a major health problem in Brazil and worldwide. The state of Santa Catarina has high endemic areas, and the disease burden is unknown. OBJECTIVES:To estimate and analyze the burden of hepatitis B in the state of Santa Catarina, in 2005 - 2010. MATERIALS AND METHODS:A time-series analysis...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.31906

    authors: Marcon CE,Schneider IJ,Schuelter-Trevisol F,Traebert J

    更新日期:2015-11-28 00:00:00

  • LRRFIP1 Inhibits Hepatitis C Virus Replication by Inducing Type I Interferon in Hepatocytes.

    abstract:BACKGROUND:Hepatitis C virus infection is one of the leading causes of end stage liver diseases. The innate immune response slows down viral replication by activating cytokines such as type I interferon (IFN-α/β), which trigger the synthesis of antiviral proteins and modulate the adaptive immune system. Recently, leuci...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.15(5)2015.28473

    authors: Liu Y,Zou Z,Zhu B,Hu Z,Zeng P,Wu L

    更新日期:2015-05-23 00:00:00

  • HAV Immunity in Iranian Medical Students.

    abstract:BACKGROUND:Hepatitis A, a fecal-oral transmitted disease, which has been considered endemic in developing countries, seems to change its pattern in developing countries because of their improved socioeconomic status. OBJECTIVES:In the present study, we aimed to determine the need of vaccination in 270 students at AJA ...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.26219

    authors: Hosseini Shokouh SJ,Dadashi A,Abiri M,Zohrevand I,Eshraghian A,Khoshdel A,Heidari B,Khoshkish S

    更新日期:2015-03-31 00:00:00

  • Decrease of serum Angiotensin converting enzyme levels upon telbivudine treatment for chronic hepatitis B virus infection and negative correlations between the enzyme levels and estimated glumerular filtration rates.

    abstract:BACKGROUND:During antiviral therapy for chronic hepatitis B, renal function impairment could be a critical concern when oral nucleot(s)ide analogues were used. Paradoxically, long-term telbivudine treatment was associated with an increase of estimated glomerular filtration rate (eGFR) through unknown mechanisms. OBJEC...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.15074

    authors: Liang KH,Chen YC,Hsu CW,Chang ML,Yeh CT

    更新日期:2014-01-31 00:00:00

  • Seroprevalence and Risk Factors for Hepatitis B in an Adult Population: The First Report from Birjand, South Khorasan, Iran.

    abstract:BACKGROUND:Infection with the hepatitis B virus (HBV) is an important global health problem. Knowledge of the geographic distribution pattern of HBV infection can help to control the spread of the disease. OBJECTIVES:To determine the prevalence of HBV infections and risk factors for the disease for the first time in B...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.36452

    authors: Ziaee M,Ebrahimzadeh A,Azarkar Z,Namaei MH,Saburi A,Fereidouni M,Bijari B,Karamian M,Sharifzadeh G

    更新日期:2016-08-14 00:00:00

  • How efficient is acoustic radiation force impulse elastography for the evaluation of liver stiffness?

    abstract:BACKGROUND:In chronic liver diseases, a correct estimation of the severity of liver fibrosis is important for recommendations regarding the treatment. Nowadays, evaluation of fibrosis is done by noninvasive methods such as biochemical scores and transient elastography instead of liver biopsy. The lack of sensitivity to...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:

    authors: Sporea I,Badea R,Sirli R,Lupsor M,Popescu A,Danila M,Focsa M,Deleanu A

    更新日期:2011-07-01 00:00:00

  • Evaluation of the effects of oral N-acetylcysteine and a placebo in paraclinical and oxidative stress parameters of patients with chronic hepatitis B.

    abstract:BACKGROUND AND AIMS:The treatment of chronic hepatitis B (CHB) is a challenging problem today, and previous study has shown that oxidative stress causes the collective pathophysiological conditions of many hepatopathies, so other new therapeutic approaches are needed. Hence, in this study the paraclinical and oxidative...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:

    authors: Shohrati M,Dermanaki F,Babaei F,Alavian SM

    更新日期:2010-04-01 00:00:00

  • Egy-score predicts severe hepatic fibrosis and cirrhosis in Egyptians with chronic liver diseases: a pilot study.

    abstract:BACKGROUND:Non-invasive methods for assessment of hepatic fibrosis are increasingly needed. Recent studies showed that combined elevation of tumor markers CA 19-9 and CA 125 is predictive of severe hepatic fibrosis or cirrhosis with high specificity. OBJECTIVES:We aimed at developing a new panel of surrogate biomarker...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.10810

    authors: Alboraie MA,Afifi ME,Elghamry FG,Shalaby HA,Elshennawy GE,Abdelaziz AA,Shaheen MU,Abo El-Seoud AR

    更新日期:2013-06-16 00:00:00

  • In Vitro Analysis of CsA-Induced Hepatotoxicity in HepG2 Cell Line: Oxidative Stress and α2 and β1 Integrin Subunits Expression.

    abstract:BACKGROUND:Cyclosporine A (CsA)-induced hepatotoxicity could be due to a reduction in α2β1 integrin expression that may either be from the direct effect of CsA itself or from reactive oxygen species (ROS) overproduction. OBJECTIVES:In this study we aimed to identify the cellular mechanisms underlying CsA-induced hepat...

    journal_title:Hepatitis monthly

    pub_type: 杂志文章

    doi:10.5812/hepatmon.11447

    authors: Mostafavi-Pour Z,Khademi F,Zal F,Sardarian AR,Amini F

    更新日期:2013-08-13 00:00:00