Interferon alpha-2b therapy in chronic hepatitis delta.

abstract：BACKGROUND:While Roux-en-Y hepaticojejunostomy (RYH) is the common anastomotic technique for liver transplantation (LT) in patients with primary sclerosing cholangitis (PSC), duct-to-duct (DD) reconstruction may be used if the recipient common bile duct is normal. There are conflicting observational data on the rate of...

journal_title：Hepatitis monthly

authors： Al-Judaibi B,Hernandez Alejandro R,Uhanova J,Marotta P,Mosli M,Chandok N

更新日期：2015-05-23 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection as a worldwide health problem is associated with cirrhosis and hepatocellular carcinoma. With current treatment regimen, pegylated interferon (PEG-IFN) plus ribavirin, sustain virological response (SVR) is achieved in only 50% of infected individuals. In HCV infection, an in...

journal_title：Hepatitis monthly

authors： Sarvari J,Norozian H,Fattahi MR,Pirbonyeh N,Moattari A

更新日期：2014-01-23 00:00:00

abstract：BACKGROUND AND AIMS:The duration of the protection of hepatitis B vaccination for infants and the necessity of a booster dose administration is unknown. The aim of the present study was to evaluate the persistence of seroprotection after hepatitis B virus (HBV) vaccination in order to determine the necessity of a singl...

journal_title：Hepatitis monthly

authors： Yazdanpanah B,Safari M,Yazdanpanah S

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV), hepatitis D virus (HDV), and human immunodeficiency virus (HIV) are transmitted by blood transfusion. Thus, hemodialysis (HD) patients are more prone to become the carriers of these infections due to their treatment demands. OBJECTIVES:The aim of this study was to assess the prevale...

journal_title：Hepatitis monthly

authors： Bahri F,Kargar Kheirabad A,Ghasemzadeh I,Shoja S,Gouklani H

更新日期：2016-01-23 00:00:00

abstract：BACKGROUND:The entire disease spectrum of chronic HBV infection (CHB) includes asymptomatic carriers (AC), active chronic hepatitis (ACH), cirrhosis (Cir), and hepatocellular carcinoma (HCC). Previous study have demonstrated that the costimulation profiles from the livers of patients influenced immune responses and pla...

journal_title：Hepatitis monthly

authors： Yin JW,Ping Huang M,Zhong B

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:In chronic liver diseases, a correct estimation of the severity of liver fibrosis is important for recommendations regarding the treatment. Nowadays, evaluation of fibrosis is done by noninvasive methods such as biochemical scores and transient elastography instead of liver biopsy. The lack of sensitivity to...

journal_title：Hepatitis monthly

authors： Sporea I,Badea R,Sirli R,Lupsor M,Popescu A,Danila M,Focsa M,Deleanu A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:There have been very few studies evaluating the close association between excess iron and cirrhosis; however, cirrhosis could be regarded as an iron-loading disorder. OBJECTIVES:In this study, the goal was to show the levels of the iron content in the liver tissue in certain types of cirrhosis. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Geramizadeh B,Ghazanfari Y,Nikeghbalian S,Malekhosseini SA

更新日期：2015-12-28 00:00:00

abstract：BACKGROUND:Hepatitis C virus infection is one of the leading causes of end stage liver diseases. The innate immune response slows down viral replication by activating cytokines such as type I interferon (IFN-α/β), which trigger the synthesis of antiviral proteins and modulate the adaptive immune system. Recently, leuci...

journal_title：Hepatitis monthly

authors： Liu Y,Zou Z,Zhu B,Hu Z,Zeng P,Wu L

更新日期：2015-05-23 00:00:00

abstract：BACKGROUND:Global prevalence of Hepatitis C Virus (HCV) infection corresponds to about 130 million HCV positive patients worldwide. The only drug that effectively reduces viral load is interferon-α (IFN-α) and currently combination of IFN and ribavirin is the choice for treatment. OBJECTIVES:The present study is aimed...

journal_title：Hepatitis monthly

authors： Kanwal S,Mahmood T

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Primary sclerosing cholangitis (PSC) as one of the most common chronic cholestatic liver diseases is a main predisposing factor for the development of cholangiocarcinoma (CCA). Biliary intraepithelial neoplasia (BilIN) is defined as precancerous bile duct epithelial changes, which can be eventually led to ch...

journal_title：Hepatitis monthly

authors： Akbarzadeh L,Geramizadeh B,Kazemi K,Nikeghbalian S,Malekhosseini S

更新日期：2016-12-14 00:00:00

abstract：BACKGROUND:Current guidelines introduce periodic monitoring of serum alanine transaminase (ALT) as the first-line modality in follow-up patients, with a hepatitis B virus (HBV) inactive carrier state. OBJECTIVES:This study aimed to determine the incidence rate and patterns of ALT fluctuations and prognostic values for...

journal_title：Hepatitis monthly

authors： Farzi H,Ebrahimi Daryani N,Mehrnoush L,Salimi S,Alavian SM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:There are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (NAFLD) in different populations. However, the existing literature lacks powerful studies addressing the factors which may predict the severity of NAFLD. OBJECTIVES:In the current study, we a...

journal_title：Hepatitis monthly

authors： Ghamar-Chehreh ME,Khedmat H,Amini M,Taheri S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in western world. However, NAFLD shows an increasing trend in China every year, which has attracted the attention of national health authorities. The previous studies have shown that NAFLD caused severe gastrointestina...

journal_title：Hepatitis monthly

authors： Lu ML,Huang H,Liu LM,Chang J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Interleukin-10 (IL-10) is an important anti-inflammatory cytokine. The polymorphisms of its promoter gene have been considered to be related with the chronicity of hepatitis B infection. OBJECTIVES:The aim of this study was to evaluate the polymorphisms at different positions in the IL-10 promoter gene in p...

journal_title：Hepatitis monthly

authors： Ghaleh Baghi S,Alavian SM,Mehrnoush L,Salimi S

更新日期：2015-07-22 00:00:00

abstract：BACKGROUND:Treatment of hepatitis C virus (HCV) infection with interferon (IFN) and ribavirin (RBV) is associated with adverse events, which may affect the patient's adherence to the treatment regimen and the treatment efficacy. OBJECTIVES:The aim of this study was to assess the sustained viral response (SVR) and inte...

journal_title：Hepatitis monthly

authors： Pawlowska M,Pilarczyk M,Foksinska A,Smukalska E,Halota W

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Genetic polymorphisms may play role in the pathophysiology of nonalcoholic steatohepatitis (NASH). OBJECTIVES:We purposed to assess the role of interleukin 6 (IL 6) and interleukin 8 (IL 8) gene polymorphisms in the pathogenesis of NASH. PATIENTS AND METHODS:Consecutive patients with biopsy proven NASH and...

journal_title：Hepatitis monthly

authors： Cengiz M,Yasar DG,Ergun MA,Akyol G,Ozenirler S

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:Precore stop codon (G1896A) mutation is one of the commonest mutations found in patients with chronic hepatitis B. However, over the years, this mutation was not reported much in Malaysia. OBJECTIVES:We therefore investigated the presence of G1896A mutation in Malaysian population and its association with H...

journal_title：Hepatitis monthly

authors： Suppiah J,Mohd Zain R,Bahari N,Haji Nawi S,Saat Z

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:Non-invasive methods for assessment of hepatic fibrosis are increasingly needed. Recent studies showed that combined elevation of tumor markers CA 19-9 and CA 125 is predictive of severe hepatic fibrosis or cirrhosis with high specificity. OBJECTIVES:We aimed at developing a new panel of surrogate biomarker...

journal_title：Hepatitis monthly

authors： Alboraie MA,Afifi ME,Elghamry FG,Shalaby HA,Elshennawy GE,Abdelaziz AA,Shaheen MU,Abo El-Seoud AR

更新日期：2013-06-16 00:00:00

abstract：BACKGROUND:About 30% of individuals with hepatitis C virus (HCV) infection are able to clear HCV spontaneously. Differences in host genetics affect the outcome of HCV infection. Single nucleotide polymorphisms (SNPs) of the Interferon lambda (IFNL) genes were associated with spontaneous and treatment-induced clearance ...

journal_title：Hepatitis monthly

authors： Sharafi H,Alavian SM,Behnava B,Pouryasin A,Keshvari M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Chronic hepatitis C (CHC) is a global infection. In Saudi Arabia, the prevalence of CHC is declining due to the implementation of a blood screening program. However, CHC still remains a leading cause of liver cirrhosis and hepatocellular carcinoma. OBJECTIVES:This is a retrospective study of CHC patients at...

journal_title：Hepatitis monthly

authors： Akbar HO,Al Ghamdi A,Qattan F,Fallatah HI,Al Rumani M

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) is able to down-regulate innate immune response. It is important to know the immune pathways that this virus interacts with. HCV non-structural protein 3 (NS3) plays an important role in this viral feature. HCV NS3 protein could affect the expression of antiviral protein such as viper...

journal_title：Hepatitis monthly

authors： Khanlari Z,Sabahi F,Hosseini SY,Ghaderi M

更新日期：2014-06-08 00:00:00

abstract：CONTEXT:We briefly reviewed the evidence on the association of hepatitis C (HCV) infection with several aspects of mental and psychosocial health. EVIDENCE ACQUISITION:Medline was searched with appropriate keywords. The primary sources were the systematic reviews. If systematic reviews were not available for a subject...

journal_title：Hepatitis monthly

authors： Modabbernia A,Poustchi H,Malekzadeh R

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) genotypes and mutations are gaining importance in determining the clinical course of chronic liver disease. OBJECTIVES:To determine and compare the distribution of HBV genotypes and genomic variations in Pakistan to other parts of the world. PATIENTS AND METHODS:We conducted a prosp...

journal_title：Hepatitis monthly

authors： Mumtaz K,Hamid S,Ahmed S,Moatter T,Mushtaq S,Khan A,Mizokami M,Jafri W

更新日期：2011-01-01 00:00:00

abstract：BACKGROUNDS:Serum hepatitis B surface antigen (HBsAg) levels are associated with fibrosis in patients with chronic hepatitis B (CHB) infection. OBJECTIVES:The aim of our study was to evaluate serum HBsAg level as a biomarker for compensated cirrhosis in hepatitis B e antigen (HBeAg) positive CHB patients. PATIENTS AN...

journal_title：Hepatitis monthly

authors： Jia W,Qi X,Ji YY,Xun YH,Wang H,Zhang WH,Yang JH,Wang JY,Zhu HX,Mao RC,Zhang JM

更新日期：2015-08-30 00:00:00

abstract：BACKGROUND:Cytokines are proteins that mediate innate and adaptive immunity responses. It is hypothesized that interferon lambda 3 (IFNL3) levels can influence the outcome of chronic hepatitis B virus (HBV) infection. Polymorphisms in IFN genes have been associated with response to infection. OBJECTIVES:This study was...

journal_title：Hepatitis monthly

authors： Heidari Z,Moudi B,Mahmoudzadeh-Sagheb H,Hashemi M

更新日期：2016-03-05 00:00:00

abstract：BACKGROUND:During antiviral therapy for chronic hepatitis B, renal function impairment could be a critical concern when oral nucleot(s)ide analogues were used. Paradoxically, long-term telbivudine treatment was associated with an increase of estimated glomerular filtration rate (eGFR) through unknown mechanisms. OBJEC...

journal_title：Hepatitis monthly

authors： Liang KH,Chen YC,Hsu CW,Chang ML,Yeh CT

更新日期：2014-01-31 00:00:00

abstract：BACKGROUND:Good knowledge, attitude and practice (KAP) of the physicians allow them to handle their patients in such a way that they prevent themselves from contracting, and their patients from spreading, the infection. However, the Iranian standardized KAP questionnaire of physicians about viral hepatitis is not avail...

journal_title：Hepatitis monthly

authors： Ghasemi S,Kabir A,Ansari Jafari M,Jalali M,Amini A,Faghihi-Kashani AH,Alavian SM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The treatment of chronic hepatitis B (CHB) is a challenging problem today, and previous study has shown that oxidative stress causes the collective pathophysiological conditions of many hepatopathies, so other new therapeutic approaches are needed. Hence, in this study the paraclinical and oxidative...

journal_title：Hepatitis monthly

authors： Shohrati M,Dermanaki F,Babaei F,Alavian SM

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Reversibility of advanced fibrosis after HCV-clearance is an important goal of therapy. OBJECTIVES:Measuring liver stiffness (LS) by transient elastography (TE) might be helpful in this setting. PATIENTS AND METHODS:We evaluated 104 patients with biopsy-proven chronic hepatitis C (CHC) and sustained virolo...

journal_title：Hepatitis monthly

authors： Calvaruso V,Di Marco V,Ferraro D,Petta S,Calì A,Grazia Bavetta M,Conte E,Luigi Almasio P

更新日期：2013-05-11 00:00:00

abstract：BACKGROUND:Hepatitis B is a common infectious disease in China. Many studies have shown that the genotype of hepatitis B virus (HBV) is probably associated with the efficacy of some antiviral drugs such as interferon α (IFN-α) and Lamivudine (LAM). However, the association between HBV genotype and adefovir dipivoxil (A...

journal_title：Hepatitis monthly

authors： Wen Z,Zhang H,Zhang M,Tan D,Li Q,Zhang H,Wu P,Deng L

更新日期：2014-08-17 00:00:00