Potentiated Osteoinductivity via Cotransfection with BMP-2 and VEGF Genes in Microencapsulated C2C12 Cells.

abstract：:The simultaneous effect of flexible wall and multiple stenoses on the flow and mass transfer of blood is investigated through numerical computation and simulations. The solution is obtained using the Marker and Cell technique on an axisymmetric model of Newtonian blood flow. The results compare favorably with physical...

journal_title：BioMed research international

authors： Alsemiry RD,Sarifuddin,Mandal PK,Sayed HM,Amin N

更新日期：2020-01-31 00:00:00

abstract：:We evaluated whether the timing of maternal hypoxia during pregnancy influenced cardiac extracellular matrix accumulation in the adult offspring. Rats in different periods of pregnancy were assigned to maternal hypoxia or control groups. Maternal hypoxia from day 3 to 21 of pregnancy or day 9 to 21 of pregnancy increa...

journal_title：BioMed research international

authors： Wang L,Li M,Huang Z,Wang Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:We performed a retrospective study to assess whether the initial molecular characteristics of glioblastomas (GBMs) were associated with the response to the bevacizumab/irinotecan chemotherapy regimen given at recurrence. RESULTS:Comparison of the genomic and gene expression profiles of the responders (n = 1...

journal_title：BioMed research international

authors： Laffaire J,Di Stefano AL,Chinot O,Idbaih A,Gallego Perez-Larraya J,Marie Y,Vintonenko N,Boisselier B,Farina P,Delattre JY,Figarella-Branger D,Honnorat J,Sanson M,Ducray F

更新日期：2014-01-01 00:00:00

abstract：Background:Inconsistent data have been reported for the effectiveness of intramuscular botulinum toxin type A (BTXA) in patients with limb spasticity after stroke. This meta-analysis of available randomized controlled trials (RCTs) aimed to determine the efficacy and safety of BTXA in adult patients with upper and lowe...

journal_title：BioMed research international

authors： Sun LC,Chen R,Fu C,Chen Y,Wu Q,Chen R,Lin X,Luo S

更新日期：2019-04-07 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most prevalent cause of liver disease worldwide and afflicts adults and children as currently associated with obesity and insulin resistance. Even though lately some advances have been made to elucidate the mechanism and causes of the disease much remain...

journal_title：BioMed research international

authors： Duarte N,Coelho IC,Patarrão RS,Almeida JI,Penha-Gonçalves C,Macedo MP

更新日期：2015-01-01 00:00:00

abstract：:This study was designed to explore the effect of basic fibroblast growth factor (bFGF) on radiation-induced endothelial dysfunction and histological changes in the urinary bladder. bFGF was administrated to human umbilical vein cells (HUVEC) or urinary bladder immediately after radiation. Reduced expression of thrombo...

journal_title：BioMed research international

authors： Zhang S,Qiu X,Zhang Y,Fu K,Zhao X,Wu J,Hu Y,Zhu W,Guo H

更新日期：2015-01-01 00:00:00

abstract：Objective:This study is aimed at evaluating the effects of platelet-rich plasma (PRP) on proliferation, viability, and odontogenic differentiation of neural crest stem-like cells (NCSCs) derived from human dental apical papilla. Materials and Methods:Cells from apical papillae were obtained and then induced to form ne...

journal_title：BioMed research international

authors： Li J,Xiang L,Guan C,Yang X,Hu X,Zhang X,Zhang W

更新日期：2020-05-09 00:00:00

abstract：:Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite continuous improvements in diagnosis and therapeutic method, the prognosis is still far away from expectations. The invasive phenotype of GBM is the main reason for the poor prognosis. Epithelial-mesenchymal transition (EMT) is r...

journal_title：BioMed research international

authors： Song Y,Chen Y,Li Y,Lyu X,Cui J,Cheng Y,Zheng T,Zhao L,Zhao G

更新日期：2019-04-17 00:00:00

abstract：Objective:To determine if increasing variability of blood pressure influences determination of cerebral autoregulation. Methods:A prospective observational study was performed at the ICU of a university hospital in the Netherlands. 13 comatose patients after cardiac arrest underwent baseline and intervention (tilting ...

journal_title：BioMed research international

authors： van den Brule JMD,van Kaam CR,van der Hoeven JG,Claassen JAHR,Hoedemaekers CWE

更新日期：2018-06-06 00:00:00

abstract：:The aim of this study was to develop a vitrification procedure for human ovarian tissue cryopreservation in order to better preserve the ovarian tissue. Large size samples of ovarian tissue retrieved from 15 female-to-male transgender subjects (18-38 years) were vitrified using two solutions (containing propylene glyc...

journal_title：BioMed research international

authors： Fabbri R,Vicenti R,Macciocca M,Pasquinelli G,Paradisi R,Battaglia C,Martino NA,Venturoli S

更新日期：2014-01-01 00:00:00

abstract：:We undertook an investigation to advance understanding of the host-range dynamics and biocontrol implications of Cochliobolus lunatus in the past decade. Potato (Solanum tuberosum L) farms were routinely surveyed for brown-to-black leaf spot disease caused by C. lunatus. A biphasic gene data set was assembled and data...

journal_title：BioMed research international

authors： Louis B,Waikhom SD,Roy P,Bhardwaj PK,Sharma CK,Singh MW,Talukdar NC

更新日期：2014-01-01 00:00:00

abstract：:Abdominal pregnancy is a very rare form of ectopic pregnancy, associated with high morbidity and mortality for both fetus and mother. It is, and often, seen in poor resource nations, where early diagnosis is often a major challenge due to poor prenatal care and lack of medical resources. An advanced abdominal pregnanc...

journal_title：BioMed research international

authors： Dabiri T,Marroquin GA,Bendek B,Agamasu E,Mikhail M

更新日期：2014-01-01 00:00:00

abstract：:This study evaluated the presence of Acanthamoeba species in the Puzih River watershed, which features typical subtropical monsoon climate and is located just above the Tropic of Cancer in Taiwan. The relationship between the seasonal and geographical distributions of Acanthamoeba species in this rivershed was also in...

journal_title：BioMed research international

authors： Kao PM,Chou MY,Tao CW,Huang WC,Hsu BM,Shen SM,Fan CW,Chiu YC

更新日期：2013-01-01 00:00:00

abstract：:Aim. The aim of this study was to describe PCa characteristics and long-term outcomes in young men aged ≤55 years after radical prostatectomy (RP) and to compare them with older men cohort. Methods. Among 2,200 patients who underwent RP for clinically localized PCa at our centre between 2001 and 2015, 277 (10.3%) men ...

journal_title：BioMed research international

authors： Milonas D,Venclovas Z,Gudinaviciene I,Zviniene K,Matjosaitis AJ

更新日期：2017-01-01 00:00:00

abstract：:The impairment of wound healing in diabetic patients is an important clinical problem affecting millions of patients worldwide. Various clinical and basic science studies show that stem cell therapy, as a regenerative medical therapy, can be a good solution. In this paper, we begin with an introduction of the cellular...

journal_title：BioMed research international

authors： Yang M,Sheng L,Zhang TR,Li Q

更新日期：2013-01-01 00:00:00

abstract：:Paclitaxel, a class of taxane with microtubule stabilising ability, has remained with platinum based therapy, the standard care for primary ovarian cancer management. A deeper understanding of the immunological basis and other potential mechanisms of action together with new dosing schedules and/or routes of administr...

journal_title：BioMed research international

authors： Kampan NC,Madondo MT,McNally OM,Quinn M,Plebanski M

更新日期：2015-01-01 00:00:00

abstract：:The presence of acquired mutations within the JAK2, CALR, and MPL genes in the majority of patients with myeloproliferative neoplasms (MPN) affords the opportunity to utilise these mutations as markers of minimal residual disease (MRD). Reduction of the mutated allele burden has been reported in response to a number o...

journal_title：BioMed research international

authors： Haslam K,Langabeer SE

更新日期：2016-01-01 00:00:00

abstract：:To investigate white matter (WM) abnormalities in neocortical epilepsy, we extract supratentorial WM parameters from raw tensor magnetic resonance images (MRI) with automated region-of-interest (ROI) registrations. Sixteen patients having neocortical seizures with secondarily generalised convulsions and 16 age-matched...

journal_title：BioMed research international

authors： Peng SJ,Harnod T,Tsai JZ,Huang CC,Ker MD,Chiou JC,Chiueh H,Wu CY,Hsin YL

更新日期：2014-01-01 00:00:00

abstract：:The immune system is traditionally considered from the perspective of defending against bacterial or viral infections. However, foreign materials like implants can also illicit immune responses. These immune responses are mediated by a large number of molecular signals, including cytokines, antibodies and reactive rad...

journal_title：BioMed research international

authors： Gardner AB,Lee SK,Woods EC,Acharya AP

更新日期：2013-01-01 00:00:00

abstract：:Natural products are valuable sources for drug discovery because they have a wide variety of useful chemical components and biological properties. A quick reevaluation of the potential therapeutic properties of established natural products was made possible by the recent development of the methodology and improvement ...

journal_title：BioMed research international

authors： Jeon YJ,Shin JI,Lee S,Lee YG,Kim JB,Kwon HC,Kim SH,Kim I,Lee K,Han YS

更新日期：2018-08-01 00:00:00

abstract：Background:The apolipoprotein E knockout (ApoE -/-) mouse model is well established for the study of terpenoids in the prevention of atherosclerosis. Studies investigating the clinical benefit of terpenoids in humans are scarce. This systematic review and meta-analysis evaluated the effects of terpenoid administration ...

journal_title：BioMed research international

authors： Liu H,Zhang Y,Sun S,Wang S

更新日期：2019-07-17 00:00:00

abstract：:Staphylococcal food-borne disease (SFD) is one of the most common food-borne diseases worldwide resulting from the contamination of food by preformed S. aureus enterotoxins. It is one of the most common causes of reported food-borne diseases in the United States. Although several Staphylococcal enterotoxins (SEs) have...

journal_title：BioMed research international

authors： Kadariya J,Smith TC,Thapaliya D

更新日期：2014-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. JAK/STAT signalling pathway is involved in autoimmune diseases and in the atherosclerotic process. JAK3 is a highly promising target for immunomodulatory drugs and polymorphisms in ...

journal_title：BioMed research international

authors： García-Bermúdez M,López-Mejías R,Genre F,Castañeda S,Corrales A,Llorca J,González-Juanatey C,Ubilla B,Miranda-Filloy JA,Pina T,Gómez-Vaquero C,Rodríguez-Rodríguez L,Fernández-Gutiérrez B,Balsa A,Pascual-Salcedo D,López-Long

更新日期：2015-01-01 00:00:00

abstract：:Objective. This study aims to extract motor ingredients through data mining from wearable sensors in a virtual reality goal-directed shoulder rehabilitation (GDSR) system and to examine their effects toward clinical assessment. Design. A single-group before/after comparison. Setting. Outpatient research hospital. Subj...

journal_title：BioMed research international

authors： Lee SH,Yeh SC,Chan RC,Chen S,Yang G,Zheng LR

更新日期：2016-01-01 00:00:00

abstract：Background:Hypertrophic pachymeningitis (HP) is generally regarded as a rare inflammatory disease, which results in a diffuse thickening of the dura mater. We retrospectively collected data from patients with HP. Methods:A total of 16 patients with HP were included in our study. The clinical features, laboratory evalu...

journal_title：BioMed research international

authors： Bi Z,Shang K,Cao J,Su Z,Bu B,Xu S,Liu C

更新日期：2020-08-14 00:00:00

abstract：:Bone marrow stromal cells (BMSCs) are a valuable resource for skeletal regenerative medicine because of their osteogenic potential. In spite of the very general term "stem cell," this population of cells is far from homogeneous, and different BMSCs clones have greatly different phenotypic properties and, therefore, po...

journal_title：BioMed research international

authors： Vianna VF,Bonfim DC,Cavalcanti Ados S,Fernandes MC,Kahn SA,Casado PL,Lima IC,Murray SS,Murray EJ,Duarte ME

更新日期：2013-01-01 00:00:00

abstract：:Oral mucosa is an attractive region for the local and systemic application of many drugs. Oral mucoadhesive films are preferred for their prolonged time of residence, the improved bioavailability of the drug they contain, their painless application, their protection against lesions, and their nonirritating properties....

journal_title：BioMed research international

authors： Landová H,Vetchý D,Gajdziok J,Doležel P,Muselík J,Dvořáčková K,Jekl V,Hauptman K,Knotek Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:India has one of the highest tuberculosis (TB) burdens globally. However, few studies have focused on TB in young children, a vulnerable population, where lack of early diagnosis results in poor outcomes. METHODS:Young children (≤ 5 years) with suspected TB were prospectively enrolled at a tertiary hospital...

journal_title：BioMed research international

authors： Jain SK,Ordonez A,Kinikar A,Gupte N,Thakar M,Mave V,Jubulis J,Dharmshale S,Desai S,Hatolkar S,Kagal A,Lalvani A,Gupta A,Bharadwaj R

更新日期：2013-01-01 00:00:00

abstract：:The main objective was to quantify the effects of five different slopes on trunk and shoulder kinematics as well as shoulder kinetic and muscular demands during manual wheelchair (MWC) propulsion on a motorized treadmill. Eighteen participants with spinal cord injury propelled their MWC at a self-selected constant spe...

journal_title：BioMed research international

authors： Gagnon D,Babineau AC,Champagne A,Desroches G,Aissaoui R

更新日期：2015-01-01 00:00:00

abstract：:Angiogenesis is essential for tumor growth and metastasis. Over the last decades, a substantial progress has been achieved in defining different patterns of tumor microcirculation. Sprouting angiogenesis, the oldest model of microcirculation, is the de novo vessel formation from preexisting blood vessels. Vessel split...

journal_title：BioMed research international

authors： Alameddine RS,Hamieh L,Shamseddine A

更新日期：2014-01-01 00:00:00