Is the effect of somatostatin on muscarinic receptors selective to M1 type?

abstract：:Enkephalin immunoreactive neurons within the nucleus tractus solitarius (NTS) were found to project to the parabrachial nucleus of the cat with the use of a combination of immunohistochemistry and retrograde transport of horseradish peroxidase. Double labelled neurons were located in the medial, parvocellular and comm...

journal_title：Brain research

authors： Maley BE,Panneton WM

更新日期：1988-03-01 00:00:00

abstract：:The intracerebroventricular injection (1 microgram) of murine corticotropin-releasing factor (r-CRF) to rats after 72 h of sleep deprivation markedly postponed the sleep onset, reduced slow wave sleep and prolonged the duration of paradoxical sleep (PS) episodes. Moreover, CRF is-to our knowledge-the first compound to...

journal_title：Brain research

authors： Marrosu F,Gessa GL,Giagheddu M,Fratta W

更新日期：1990-05-07 00:00:00

abstract：:To identify parameters of optic tract growth that may be independent of the region of the CNS in which the tract develops, eye primordia of embryonic Rana pipiens were transplanted to a variety of ectopic locations adjacent to the hindbrain and spinal cord. Longitudinal growth direction, cross-sectional growth positio...

journal_title：Brain research

authors： Constantine-Paton M

更新日期：1978-12-08 00:00:00

abstract：:The existence of multiple brain melanocortin receptor types has been postulated, based on the complex pharmacology of intracerebrally administered melanocortin (melanocyte-stimulating hormone-related) peptides. In this study, this hypothesis was tested by determining whether different brain melanocortin receptor popul...

journal_title：Brain research

authors： Tatro JB,Entwistle ML

更新日期：1994-01-28 00:00:00

abstract：:A comparison of morphological and biochemical characteristics of the D1-type dopamine receptor has been assessed in two experimental tissues, the superior cervical ganglion (SCG) and caudate nucleus of the rat. Correlation of the distribution of this dopaminergic binding site using in vitro autoradiographic localizati...

journal_title：Brain research

authors： Ariano MA

更新日期：1987-09-22 00:00:00

abstract：:Preconditioning-induced cellular adaptation is a new therapeutic strategy for ischemic stroke. This research aims to examine the role of peroxisome proliferator activated receptor (PPAR)-γ co-activator 1-α (PGC-1α) and hypoxia induced factor-1α (HIF-1α) in hypoxic preconditioning-induced protection. In this study, rat...

journal_title：Brain research

authors： Zhao J,Li L,Pei Z,Li C,Wei H,Zhang B,Peng Y,Wang Y,Tao Y,Huang R

更新日期：2012-04-04 00:00:00

abstract：:Single motor unit activity was recorded from human lower lip muscles while subjects maintained a firing rate of 20 ips using audio and visual feedback. Each motor unit was classified as belonging to one of three muscles, orbicularis oris inferior (OOI), mentalis (MENT), or depressor labii inferior (DLI). Reflex respon...

journal_title：Brain research

authors： McClean MD,Smith A

更新日期：1982-11-11 00:00:00

abstract：:The hyperphagic properties of insulin (10 U/kg, s.c.) were transiently (2h) and dose-dependently inhibited (30%) by central pretreatment with naltrexone (20-50 micrograms, i.c.v.). The irreversible mu opioid antagonist, beta-funaltrexamine (B-FNA, 20 micrograms, i.c.v.) significantly inhibited insulin hyperphagia by 2...

journal_title：Brain research

authors： Beczkowska IW,Bodnar RJ

更新日期：1991-05-03 00:00:00

abstract：:The effects of repetitive pilocarpine-induced status epilepticus (SE) in the hippocampal Na(+)/K(+)ATPase activity were studied in developing rat. Na(+)/K(+)ATPase is a membrane-bound enzyme responsible for the active transport of sodium and potassium ions through the membrane. It is necessary to maintain neuronal exc...

journal_title：Brain research

authors： Reime Kinjo E,Arida RM,Mara de Oliveira D,da Silva Fernandes MJ

更新日期：2007-03-23 00:00:00

abstract：:We identified cell bodies of a pair of the cardio-inhibitory (CI) neurons in the first thoracic ganglion (TG1) of Bathynomus doederleini. Each of the cell bodies gives rise to a single axon, which runs into the contralateral hemiganglion of TG1 via the commissure and runs to the heart via the fourth root as CI axon. S...

journal_title：Brain research

authors： Tanaka K,Kuwasawa K

更新日期：1991-09-06 00:00:00

abstract：:ACTH4-10, a fragment of the adrenocorticotropic hormone (ACTH) molecule, has marked effects on the compensation process following unilateral labyrinthectomy. In Rana temporaria ACTH4-10-treatment (5-250 micrograms/kg) influences both the acquisition and the maintenance of the compensated state. The compensation proces...

journal_title：Brain research

authors： Flohr H,Lüneburg U

更新日期：1982-09-23 00:00:00

abstract：:Repeated sensory exposure through frequent consumption of certain foods leads to changes in the processing of sensory cues. We investigated the influence of frequent minty chewing gum consumption on the neurobehavioral processing of intranasal trigeminal and olfactory stimuli. fMRI responses to a trigeminal minty odor...

journal_title：Brain research

authors： Han P,Penzler M,Jonathan W,Hummel T

更新日期：2020-03-01 00:00:00

abstract：:The effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (PVN) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (ACTH1-24) was studied in male rats. In sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and ACTH1-...

journal_title：Brain research

authors： Argiolas A,Melis MR,Mauri A,Gessa GL

更新日期：1987-09-22 00:00:00

abstract：:Following single injections of horseradish peroxidase (HRP) in the superior colliculus (SC) and [3H]proline in the striate cortex of rats, a close correspondence was observed in the topographical arrangements of extrastriate cortical fields of HRP retrograde label and of isotope anterograde label. These results suppor...

journal_title：Brain research

authors： Olavarria J,Van Sluyters RC

更新日期：1982-06-24 00:00:00

abstract：:Dopamine-beta-hydroxylase (DBH), the enzyme that converts dopamine to norepinephrine, has been localized in light and electron microscopic preparations of rat brain by an immunocytochemical method using a peroxidase--anti-peroxidase Fab complex. In light microscopic preparations, DBH-specific reaction product was obse...

journal_title：Brain research

authors： Cimarusti DL,Saito K,Vaughn JE,Barber R,Roberts E,Thomas PE

更新日期：1979-02-16 00:00:00

abstract：:Recently the nuclear proto-oncogene c-fos has been shown to be rapidly and transiently expressed following seizures in many types of epilepsies. Until now, immunohistochemical as well as in situ hybridization studies have reported that the dentate gyrus of the hippocampus and most of the cortical areas were invariably...

journal_title：Brain research

authors： Le Gal La Salle G,Naquet R

更新日期：1990-06-04 00:00:00

abstract：:In synaptosomal preparations from rat cerebral cortex, ouabain-sensitive Rb+ uptake was stimulated by ethanol (20-80 mM). Based on differential sensitivity to ouabain, 80% of this Na+,K(+)-ATPase activity represented activity of the alpha 1 isozyme while 20% was due to the alpha 2 and/or alpha 3 isozymes (alpha 2/ alp...

journal_title：Brain research

authors： Foley TD,Rhoads DE

更新日期：1994-08-08 00:00:00

abstract：:Myelin of several Caudata (Urodela) species appears to be unique in the fact that it lacks hydroxycerebrosides and hydroxysulfatides although it contains their non-hydroxy counterparts. Comparison of the nerve conduction velocities in the Urodeles Necturus (salamander) and Notophthalmus (newt) with that in a reptile, ...

journal_title：Brain research

authors： Ki PF,Kishimoto Y,Lattman EE,Stanley EF,Griffin JW

更新日期：1985-10-14 00:00:00

abstract：:We have previously demonstrated that Fos immunoreactivity can be stimulated by KCl, forskolin or glutamate in cultured tyrosine hydroxylase-immunoreactive (TH-ir) hypothalamic neurons. The present study was performed to determine whether agents that regulate dopaminergic activity, particularly D1 and D2 receptor agoni...

journal_title：Brain research

authors： Sim LJ,Selley DE,Tsai KP,Morris M

更新日期：1994-07-18 00:00:00

abstract：:A site-specific antibody against the principal gap junctional protein in heart (connexin 43) was used to determine immunohistochemically the cellular localization of this protein in rat brain. Structures labelled with the antibody included gap junctional membranes between glial, ependymal, pial and arachnoid cells as ...

journal_title：Brain research

authors： Yamamoto T,Ochalski A,Hertzberg EL,Nagy JI

更新日期：1990-02-05 00:00:00

abstract：:The levels of N-acetyl-aspartate (NAA) and N-acetyl-aspartyl-glutamate (NAAG) were measured in several regions and in whole brain of rats from 15 days of gestation (DG) to adulthood by means of an isocratic HPLC method. The levels of NAAG in whole brain increased 3-fold between 15 DG and birth, which was 90% of the ad...

journal_title：Brain research

authors： Koller KJ,Coyle JT

更新日期：1984-07-01 00:00:00

abstract：:Choline acetyltransferase (ChAT) and glutamic acid decarboxylase (GAD) activities were measured in various visual structures of the pigeon brain after long-term monocular deprivation followed by short-term binocular presence or absence of light stimulation. The short-term phase (45 min) was coupled with a 2-deoxygluco...

journal_title：Brain research

authors： Bagnoli P,Burkhalter A,Vischer A,Henke H,Cuénod M

更新日期：1982-09-16 00:00:00

abstract：:Recently, [125I]S(-)5-OH-PIPAT (5-hydroxy-2-(N-n-propyl-N-3'-iodo-2'-propenyl)amino-tetralin) was reported to be a selective radioiodinated ligand for dopamine D2-like receptors. This ligand displayed a high binding affinity (Kd = 0.3-0.4 nM) and an agonist binding profile to dopamine D2 and D3 receptors expressed in ...

journal_title：Brain research

authors： Vessotskie JM,Kung MP,Chumpradit S,Kung HF

更新日期：1997-12-05 00:00:00

abstract：:Retinal afferents to the dorsal raphe nucleus (DRN) have been described in a number of species, including Mongolian gerbils, but functional correlates of this optic pathway are unknown at present. To determine whether temporally modulated photostimulation can affect c-Fos expression in the gerbil DRN, quantitative ana...

journal_title：Brain research

authors： Fite KV,Wu PS,Bellemer A

更新日期：2005-01-21 00:00:00

abstract：:The alpha7 nicotinic receptor agonist 3-[2,4-dimethoxybenzylidene]anabaseine (DMXB; GTS-21) was investigated for its ability to: (1) activate a variety of nicotinic receptor subtypes in Xenopus oocytes; (2) improve passive avoidance and spatial Morris water task performances in mecamylamine-sensitive manners in bilate...

journal_title：Brain research

authors： Meyer EM,Tay ET,Papke RL,Meyers C,Huang GL,de Fiebre CM

更新日期：1997-09-12 00:00:00

abstract：:(2E)-(5-Hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid (NCS-382) is an antagonist for gamma-hydroxybutyric acid (GHB) at GHB receptor sites. Advantages of using [(3)H]NCS-382 over [(3)H]GHB in radioligand binding studies are that unlike GHB, NCS-382 does not appear to bind to, activate, or i...

journal_title：Brain research

authors： Gould GG,Mehta AK,Frazer A,Ticku MK

更新日期：2003-07-25 00:00:00

abstract：:Histaminergic neurons of the tuberomammillary nucleus (TMN) are hypothesized to promote wakefulness, but little is known about the activity of these cells during spontaneous behavior. We measured histaminergic neuron activity in the dorsomedial, ventrolateral, and caudal TMN at four different times using Fos and adeno...

journal_title：Brain research

authors： Ko EM,Estabrooke IV,McCarthy M,Scammell TE

更新日期：2003-12-05 00:00:00

abstract：:Prior studies indicate that, in tests of recognition memory, ERPs elicited by correctly recognized test items differ according to whether the items were encoded in an emotionally arousing or an emotionally neutral study context. These prior studies employed only a relatively brief (ca. 10 min) retention interval, howe...

journal_title：Brain research

authors： Jaeger A,Johnson JD,Corona M,Rugg MD

更新日期：2009-05-07 00:00:00

abstract：:The effects of acetylcholine (ACh) and physostigmine (PHY) on thoracic ganglion neurons of Locusta migratoria were investigated using whole-cell and cell-attached voltage clamp. ACh activated whole-cell currents with variable amplitudes, time course and ion channel block between cells, suggesting differential expressi...

journal_title：Brain research

authors： van den Beukel I,van Kleef RG,Zwart R,Oortgiesen M

更新日期：1998-04-13 00:00:00

abstract：:The blood-brain barrier (BBB) restricts the entry of antiviral agents into the CNS thereby facilitating the creation of a reservoir of HIV that could potentially reinfect peripheral tissues. We characterized the efflux from brain of radioactively labeled viral coat HIV-1 gp120 (I-gp120) after intracerebroventricular (...

journal_title：Brain research

authors： Cashion MF,Banks WA,Bost KL,Kastin AJ

更新日期：1999-03-20 00:00:00