Corticotropin-releasing factor (CRF) increases paradoxical sleep (PS) rebound in PS-deprived rats.

abstract：:Immunohistochemical localization of brain-derived neurotrophic factor (BDNF) in the monkey brain was investigated using a polyclonal anti-BDNF antibody produced in our laboratory. The antibody recognized a single band in monkey brain homogenates, and the estimated molecular weight was approximately 14 kDa, which corre...

journal_title：Brain research

authors： Kawamoto Y,Nakamura S,Kawamata T,Akiguchi I,Kimura J

更新日期：1999-03-13 00:00:00

abstract：:The pyrithiamine-treated rats produced by our method histopathologically exhibited the edematous lesion not only around the third ventricle and at the tegmentum of pons, as expected, but also in the cerebral cortex. These animals were, therefore, used in a biochemical study of the cerebral cortex, in particular, gluco...

journal_title：Brain research

authors： Takahashi H,Nakazawa S,Yoshino Y,Shimura T

更新日期：1988-02-16 00:00:00

abstract：:By use of the push-pull perfusion technique, release of neuronal cholecystokinin-like immunoreactivity (CCK-LI) from hypothalamus of owl monkeys was investigated in relation to an intragastric meal. In overnight fasted, halothane-anesthetized owl monkeys, levels of CCK-LI in the hypothalamic push-pull perfusate were b...

journal_title：Brain research

authors： Schick RR,Reilly WM,Roddy DR,Yaksh TL,Go VL

更新日期：1987-08-18 00:00:00

abstract：:Melatonin is synthesized rhythmically under control of circadian oscillators by the retinas of non-mammalian vertebrates. Here we report that the retinas of some strains of laboratory mice exhibit robust circadian rhythms of melatonin synthesis which can be entrained by light in vitro. The rd mutation results in progr...

journal_title：Brain research

authors： Tosini G,Menaker M

更新日期：1998-04-13 00:00:00

abstract：:The nicotine and muscarinic responses of differentiated mouse neuroblastoma cells from the clonal line N1E 115 to applied cholinergic agents were recorded using single channel and whole cell patch clamp techniques. An inward macroscopic current induced by acetylcholine (ACh) at the resting potential was blocked by cur...

journal_title：Brain research

authors： Takeda K,Shimahara T,Tauc L,Berwald-Netter Y

更新日期：1986-11-19 00:00:00

abstract：:Blink movement metrics were studied in three alert cynomolgus monkeys using electromagnetic search coils attached to the eyelids bilaterally. Monkey blinks averaged approximately 24 degrees. Down-phase peak velocities were approximately twice those of the corresponding up phases. Most blinks were symmetrical with clos...

journal_title：Brain research

authors： Porter JD,Stava MW,Gaddie IB,Baker RS

更新日期：1993-04-23 00:00:00

abstract：:Lysosomal storage diseases are a heterogeneous group of hereditary disorders characterized by a deficiency in lysosomal function. Although these disorders differ in their etiology and phenotype those that affect the nervous system generally manifest as a profound deterioration in neurologic function with age. Over the...

journal_title：Brain research

authors： Phinney DG,Isakova IA

更新日期：2014-07-21 00:00:00

abstract：:Three priming injections with the D1/D2 dopamine agonist apomorphine permits a challenge with the D2 agonist quinpirole to elicit robust contralateral rotation and ipsilateral striatal Fos expression in 6-hydroxydopamine lesioned rats. Pretreatment with NMDA glutamate antagonists MK-801 or CPP dose-dependently attenua...

journal_title：Brain research

authors： Pollack AE,Haisley EC

更新日期：2001-04-06 00:00:00

abstract：:Lamprey retriculospinal neurons show phasic oscillations of their membrane potential during fictive locomotion. This modulation originates from the spinal cord locomotor networks. The aim of the present study was to elucidate the pattern of discharge of the spino-bulbar axons responsible for this modulation. Experimen...

journal_title：Brain research

authors： Vinay L,Grillner S

更新日期：1992-06-05 00:00:00

abstract：:Treatment of rat brain sections and of thalamic and striatal membranes with phosphatidylinositol phospholipase C (PIPLC), an enzyme known to hydrolyse only phosphatidylinositol and its derivatives, significantly alters the specific binding of mu- and delta-opioid ligands on their receptors. These results suggest that ...

journal_title：Brain research

authors： Trovero F,Glowinski J,Lévy M

更新日期：1990-12-24 00:00:00

abstract：:Insulin and the insulin-like growth factors (IGFs) may directly affect the growth, development, and maintenance of the vertebrate nervous system. Previous in vitro studies have focused on embryonic nervous tissue. In this study the effects of insulin, IGF-I, IGF-II and nerve growth factor (NGF) on regeneration and neu...

journal_title：Brain research

authors： Fernyhough P,Willars GB,Lindsay RM,Tomlinson DR

更新日期：1993-04-02 00:00:00

abstract：:The rat medial prefrontal cortex is known to have diverse brain functions such as learning and memory, attention, and behavioral flexibility. Although these functions are affected by monoamines (dopamine (DA), noradrenaline (NA) and serotonin (5-HT)) and acetylcholine (ACh), the detailed mechanisms remain unclear. The...

journal_title：Brain research

authors： Imai H,Matsukawa M,Okado N

更新日期：2004-06-25 00:00:00

abstract：:An increase in medial perforant synaptic strength can be observed for hippocampal slices from rats exposed to environmental enrichment. The expression of enhanced synaptic strength exhibits properties similar to long-term potentiation (LTP), a physiological model of memory storage. Similarities include an increase in ...

journal_title：Brain research

authors： Foster TC,Gagne J,Massicotte G

更新日期：1996-10-14 00:00:00

abstract：:Microinfusions of the benzodiazepine anxiolytic midazolam into the central or basolateral amygdaloid nuclei produced different anxiolytic effects in two tests of rat 'anxiety'. Infusions into the basolateral nucleus impaired open-arm avoidance in the elevated plus-maze test, but did not impair shock-probe avoidance in...

journal_title：Brain research

authors： Pesold C,Treit D

更新日期：1995-02-13 00:00:00

abstract：:alpha-Motoneurons innervating the triceps surae and short plantar muscles were stained intracellularly with horseradish peroxidase (HRP) in 0-44-day-old kittens and adult cats. The terminal arborizations of the recurrent axon collaterals in the spinal cord were studied in the light microscope (LM). The short plantar m...

journal_title：Brain research

authors： Cullheim S,Ulfhak B

更新日期：1985-01-01 00:00:00

abstract：:Somatosensory evoked potentials (SEPs) elicited by right posterior tibial nerve stimulation were simultaneously recorded from 21-27 epidural electrodes in three monkeys. N23-P40 was recorded anterior to the left central sulcus, and P23-N40 was recorded on the parietal midline and the middle portion of the right hemisp...

journal_title：Brain research

authors： Hayashi N,Nishijo H,Endo S,Ono T

更新日期：1997-11-07 00:00:00

abstract：:Thalamocortical connections were studied after injections of retrograde tracers were made into rostral or caudal parts of cortical area Fr2 in adult rats. The data reveal that both rostral Fr2 (rFr2) and caudal Fr2 (cFr2) receive input from the centrolateral, central medial, interanteromedial, mediodorsal, paracentral...

journal_title：Brain research

authors： Hicks RR,Huerta MF

更新日期：1991-12-24 00:00:00

abstract：:Glia represents the most numerous group of nervous system cells and CNS development and function depend on glial cells. We developed a purified Muller glia culture to investigate the expression of several neurotransmitter markers on these cells, such as dopaminergic, cholinergic, GABAergic and peptidergic receptors or...

journal_title：Brain research

authors： Kubrusly RC,da Cunha MC,Reis RA,Soares H,Ventura AL,Kurtenbach E,de Mello MC,de Mello FG

更新日期：2005-03-21 00:00:00

abstract：:To investigate the role of Ca2+ in astrocyte volume regulation, we determined Ca2+ fluxes following hypoosmotic stress and how these fluxes were modified by cyclic AMP. In isoosmotic conditions treatment with dibutyryl cyclic AMP (dBcAMP) caused almost a twofold increase in 45Ca2+ uptake. Efflux studies of 45Ca2+ in d...

journal_title：Brain research

authors： Bender AS,Mantelle LL,Norenberg MD

更新日期：1994-05-09 00:00:00

abstract：:The effects of undernutrition during pregnancy and/or lactation periods on cortical structures have already been reported. However, its effect on non-cortical areas like the hypothalamic, that participates in the regulation of the autonomic nervous system or food intake, has not been extensively investigated. We studi...

journal_title：Brain research

authors： González-Pardo H,Gutiérrez-Sánchez JM,Menéndez-Patterson A,Arias JL

更新日期：1994-08-15 00:00:00

abstract：:The neuropeptide nociceptin/orphanin FQ (N/OFQ), the endogenous agonist of the N/OFQ peptide receptor (NOP receptor), has been demonstrated to be involved in many physiological and pathological functions including pain regulation. In the present study, the involvement of N/OFQ-NOP receptor system in electroacupuncture...

journal_title：Brain research

authors： Fu X,Wang YQ,Wu GC

更新日期：2006-03-17 00:00:00

abstract：:The effect of a dihydropyridine Ca2+ antagonist, cilnidipine, on voltage-dependent Ca2+ channels was studied in acutely dissociated rat CA1 pyramidal neurons using the nystatin-perforated patch recording configuration under voltage-clamp conditions. Cilnidipine had no effect on low-voltage-activated (LVA) Ca2+ channel...

journal_title：Brain research

authors： Murai Y,Uneyama H,Ishibashi H,Takahama K,Akaike N

更新日期：2000-01-31 00:00:00

abstract：:Astrocytes provide structural, trophic and metabolic support to neurons and modulate synaptic activity. Under physiological conditions, neuronal-derived nitric oxide (NO) plays an important role in the modulation of a variety of central nervous system (CNS) functions. NO, although short lived, can travel sufficient di...

journal_title：Brain research

authors： Nanetti L,Vignini A,Moroni C,Pessina GP,Mazzanti L

更新日期：2004-09-10 00:00:00

abstract：:This study evaluates the neuroprotective effects of geranylgeranylacetone (GGA), which is known as an antiulcer agent and more recently as a heat-shock and other neuroprotective protein inducer, on secondary degeneration after spinal cord injury in rats. Crush injuries were produced at the T8 level using an extradural...

journal_title：Brain research

authors： Fujiki M,Furukawa Y,Kobayashi H,Abe T,Ishii K,Uchida S,Kamida T

更新日期：2005-08-16 00:00:00

abstract：:Nitric oxide (NO) can have opposite effects on peripheral sensory neuron sensitivity depending on the concentration and source of NO, and the experimental setting. The aim of this study was to determine the role of endogenous NO production in the regulation of mechanosensitive Ca(2+) influx of dorsal root ganglion (DR...

journal_title：Brain research

authors： Chaban VV,McRoberts JA,Ennes HS,Mayer EA

更新日期：2001-06-08 00:00:00

abstract：:Perinatal exposure to cannabinoids has been shown to elicit central nervous system impairment in rodents. This includes changes in monoaminergic and neuropeptidergic activities. We have examined the effect of perinatal exposure to delta 9-tetrahydrocannabinol (delta 9-THC) on sensitivity to radiant heat in both male a...

journal_title：Brain research

authors： Vela G,Fuentes JA,Bonnin A,Fernández-Ruiz J,Ruiz-Gayo M

更新日期：1995-05-22 00:00:00

abstract：:Subnanomolar concentrations of melatonin inhibit cyclic AMP and cyclic GMP accumulation in neonatal rat anterior pituitary stimulated in vitro with luteinizing-hormone releasing-hormone. Melatonin also inhibited forskolin-stimulated cyclic AMP accumulation in pars tuberalis. Inhibition of cyclic AMP accumulation is sp...

journal_title：Brain research

authors： Vanĕcek J,Vollrath L

更新日期：1989-12-25 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by upper and lower motor neuron death with ascending paralysis leading to death. In a transgenic mouse model of ALS (SOD1-G93A) weakness appears at 3 months of age, and because of progressive paralysis leads to death by 5 months. Cyclospo...

journal_title：Brain research

authors： Keep M,Elmér E,Fong KS,Csiszar K

更新日期：2001-03-16 00:00:00

abstract：:At present, the ability of polyunsaturated fatty acids (PUFAs) to regulate individual glutamate transporter subtypes is poorly understood and very little information exists on the mechanism(s) by which PUFAs achieve their effects on the transport process. Here we investigate the effect of cis-4,7,10,13,16,19-docosahex...

journal_title：Brain research

authors： Berry CB,Hayes D,Murphy A,Wiessner M,Rauen T,McBean GJ

更新日期：2005-03-10 00:00:00

abstract：:Cerebral vascular density is correlated with metabolic demands, which increase in highly active brain areas. External inputs are an essential requirement in the modeling of the visual cortex. Experience-mediated development is very active during the first postnatal month, when congruous blood supply is needed. We stud...

journal_title：Brain research

authors： Argandoña EG,Lafuente JV

更新日期：2000-02-07 00:00:00