HB-EGF expression as a potential biomarker of acquired middle ear cholesteatoma.

abstract：:It is well documented that quinine induces reversible hearing loss and tinnitus. The purpose in this study was to induce a quinine hearing loss and to investigate if verapamil, a Ca2+ channel antagonist of L-type might affect the response. Pigmented guinea pigs (n = 24) were anaesthetized by atropine. Hypnorm and mida...

journal_title：Acta oto-laryngologica

authors： Jäger W,Idrizbegovic E,Karlsson KK,Alván G

更新日期：1997-01-01 00:00:00

abstract：:The effect of adaptation of the ear on the SISI test was studied at 500 Hz and 2000 Hz in 43 patients with chronic otitis and in 20 patients with otosclerosis. The mean adaptation was slightly over 10 dB, except in the otosclerosis group at 2000 Hz, for which the value was nearly 20 dB after continuous stimulation at ...

journal_title：Acta oto-laryngologica

authors： Rahko T

更新日期：1975-07-01 00:00:00

abstract：CONCLUSION:Our results indicate that siRNA E6 and/or E7 may have potential as a gene-specific therapy for human papillomavirus (HPV) type 16 (HPV16)-related squamous cell carcinoma of the head and neck (HNSCC). OBJECTIVES:To evaluate the effectiveness of siRNA targeting E6 and/or E7 on the in vitro and in vivo growth ...

journal_title：Acta oto-laryngologica

authors： Adhim Z,Otsuki N,Kitamoto J,Morishita N,Kawabata M,Shirakawa T,Nibu K

更新日期：2013-07-01 00:00:00

abstract：:In the last few years the use of ABR in the dysmetabolic encephalopathies has aroused considerable interest. Even though brainstem involvement in these syndromes is not yet entirely understood, ABR techniques have provided new and important insights. We studied 60 insulin-dependent diabetic subjects, 29 females and 31...

journal_title：Acta oto-laryngologica

authors： Martini A,Comacchio F,Fedele D,Crepaldi G,Sala O

更新日期：1987-05-01 00:00:00

abstract：CONCLUSION:This study demonstrated that five Cx26 mutations (R32H, S199F, 572delT, 631-632delGT, and Y155X) affect gap junction (GJ) functions by causing impaired membrane targeting and aberrant cellular localization, and one mutation (R165W) leads to a constriction of the channel pore with no dye coupling. OBJECTIVE:...

journal_title：Acta oto-laryngologica

authors： Xiao Z,Yang Z,Liu X,Xie D

更新日期：2011-01-01 00:00:00

abstract：:In this study auditory brainstem responses (ABRs) were recorded repeatedly in three awake cats before and after bilateral aspiration of the inferior colliculi (ICs). All surgical procedures were performed under anaesthesia with Nembutal. Postoperative recordings were obtained 1 week, 3 months, 8 months and 13 months a...

journal_title：Acta oto-laryngologica

authors： Kaga K,Yamada K,Tsuzuku T,Uno A

更新日期：1999-03-01 00:00:00

abstract：CONCLUSIONS:Thorough otomicroscopical examination of the tympanic membrane in acute otitis media (AOM) might distinguish AOM episodes caused by different bacteria. It thus might be a way to select appropriate treatment for each patient without raising the number of dangerous complications. OBJECTIVES:The aim of this s...

journal_title：Acta oto-laryngologica

authors： Foglé-Hansson M,White P,Hermansson A

更新日期：2007-09-01 00:00:00

abstract：:In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...

journal_title：Acta oto-laryngologica

authors： Yamanobe S,Harris JP,Keithley EM

更新日期：1993-03-01 00:00:00

abstract：CONCLUSION:Reconstruction with a vascularized bone flap provided superior postoperative outcomes compared with reconstruction with a soft tissue free flap. However, patients obtained acceptable long-term functional outcomes even with a soft tissue free flap and this method is an option in selected patients. A multidisc...

journal_title：Acta oto-laryngologica

authors： Mizukami T,Hyodo I,Fukamizu H,Mineta H

更新日期：2013-12-01 00:00:00

abstract：:Normal subjects were exposed to two kinds of optokinetic stimulation, viz. at speeds of 60 degrees/s and 90 degrees/s preceded by acceleration at 6 degrees/s2 and 4.5 degrees/s2, respectively. In most subjects the speed of the eye in the slow nystagmus phase equalled the speed of the rotating device during the acceler...

journal_title：Acta oto-laryngologica

authors： Mizukoshi K,Fabian P,Stahle J

更新日期：1977-09-01 00:00:00

abstract：CONCLUSION:This study demonstrated differential gene expression profiles in salicylate ototoxicity with oligonucleotide microarray. This study may also provide basic information on candidate genes associated with hearing loss and/or tinnitus or recovery after salicylate-induced cochlear dysfunction. OBJECTIVES:Salicyl...

journal_title：Acta oto-laryngologica

authors： Im GJ,Jung HH,Chae SW,Cho WS,Kim SJ

更新日期：2007-05-01 00:00:00

abstract：CONCLUSIONS:Proteases in fungi interact with nasal epithelial cells and enhance the production of inflammatory cytokines in vitro. These cytokines induced the migration of eosinophils and neutrophils. Protease-activated receptors (PARs) might also play a role in the process of epithelial cell activation. OBJECTIVE:The...

journal_title：Acta oto-laryngologica

authors： Shin SH,Lee YH,Jeon CH

更新日期：2006-12-01 00:00:00

abstract：:The objective of this study was to develop and test an endolabyrinthic microsurgical procedure for treatment of vertigo, the utriculostomy. This involves the application of local heat for obtaining a fistula in the membranous labyrinth, so as to establish communication between the endolymphatic and perilymphatic space...

journal_title：Acta oto-laryngologica

authors： Lavinsky L,Goycoolea M,Gananca MM,Zwetsch Y

更新日期：1999-01-01 00:00:00

abstract：:We investigated the postoperative conditions of ears and the hearing acuity of patients who underwent posterior canal wall reconstruction tympanoplasty for operated ears with open mastoid. The study included 118 ears of 105 patients (57 males, 48 females; age range 5-75 years) and the patients were followed for > 1 ye...

journal_title：Acta oto-laryngologica

authors： Sasaki Y,Iino Y,Suzuki J

更新日期：2002-04-01 00:00:00

abstract：:Intense sound stimulation may result in excessive glutamate release from the inner hair cells, resulting in binding to the postsynaptic glutamate receptors and leading to neuronal degeneration and functional impairment. In this study we investigated the therapeutic effect and time window of caroverine, an N-methyl-D-a...

journal_title：Acta oto-laryngologica

authors： Chen Z,Ulfendahl M,Ruan R,Tan L,Duan M

更新日期：2003-10-01 00:00:00

abstract：CONCLUSION:This study provides evidence that histamine induced MUC5AC mRNA expression through the activation of the core region of its promoter. It may also help in approaching new therapeutic strategies in airway mucins hypersecretory diseases. OBJECTIVE:Mucin hypersecretion characterizes several respiratory diseases...

journal_title：Acta oto-laryngologica

authors： Xu F,Zhang L,Gao J,Wang D

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Laryngeal squamous cell carcinoma (LSCC) is rare in the young. OBJECTIVES:We characterized the clinical behavior of LSCC and assessed the presentation of second primary tumors (SPCs) in this patient population. MATERIALS AND METHODS:Data from the Finnish Cancer Registry (FCR) were used to identify an epide...

journal_title：Acta oto-laryngologica

authors： Silén S,Haapaniemi A,Dickinson A,Rönn K,Mäkitie A

更新日期：2019-01-01 00:00:00

abstract：CONCLUSION:Coexistent migraine affects relevant clinical features of patients with Ménière's disease (MD). OBJECTIVE:Epidemiological studies have shown an association between migraine and MD. We sought to determine whether the coexistence of migraine affects any clinical features in patients with MD. PATIENTS AND MET...

journal_title：Acta oto-laryngologica

authors： Cha YH,Brodsky J,Ishiyama G,Sabatti C,Baloh RW

更新日期：2007-12-01 00:00:00

abstract：:Following responses to constant velocity and sinusoidally oscillating movements of the whole visual environment were examined in normal subjects wearing blinkers to obscure central vision or subjected to a photo flash to induce a central scotoma, in patients with central scotomas of pathological origin and in one pati...

journal_title：Acta oto-laryngologica

authors： Gresty M,Halmagyi M

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To investigate the hearing prognosis of idiopathic sudden sensorineural hearing loss (SSNHL) treated with different initial therapies. METHODS:Subjects consisted of patients diagnosed with idiopathic SSNHL within 7 days from onset and showing severe hearing loss (≥60 dB), who were registered in a Japanese mu...

journal_title：Acta oto-laryngologica

authors： Okada M,Hato N,Nishio SY,Kitoh R,Ogawa K,Kanzaki S,Sone M,Fukuda S,Hara A,Ikezono T,Ishikawa K,Iwasaki S,Kaga K,Kakehata S,Matsubara A,Matsunaga T,Murata T,Naito Y,Nakagawa T,Nishizaki K,Noguchi Y,Sano H,Sato

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:We used ocular vestibular evoked myogenic potentials to investigate the relationship between residual dizziness and utricular function following the canalith repositioning procedure for benign paroxysmal positional vertigo. METHODS:Ocular vestibular evoked myogenic potentials were measured in 44 patients (40...

journal_title：Acta oto-laryngologica

authors： Seo T,Shiraishi K,Kobayashi T,Mutsukazu K,Fujita T,Saito K,Watanabe H,Doi K

更新日期：2017-11-01 00:00:00

abstract：:The purpose of this study was to show the early stages of polyp formation, as part of our studies on the pathogenesis of nasal polyps. Two and 4 weeks after experimental tubal occlusion in 18 Wistar rats, 13 showed signs of bacterial infection, respective acute otitis media. In the majority of these rats polypouslike ...

journal_title：Acta oto-laryngologica

authors： Larsen PL,Tos M

更新日期：1991-01-01 00:00:00

abstract：:Thirty-two patients affected by idiopathic benign paroxysmal positional vertigo (BPPV) of the posterior semicircular canal were studied before, 3 days and I month after a resolutive Semont manoeuvre by means of dynamic posturography. The overall postural control in BPPV patients was shown to be impaired, as demonstrat...

journal_title：Acta oto-laryngologica

authors： Di Girolamo S,Paludetti G,Briglia G,Cosenza A,Santarelli R,Di Nardo W

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:ABO blood group status may be a risk factor for some diseases, including hearing loss. Individuals with blood group O show a higher prevalence of hearing loss after industrial noise exposure. Group O individuals with normal hearing show reduced amplitudes in otoacoustic emission recordings. Whether blood gro...

journal_title：Acta oto-laryngologica

authors： Yang Y,Hood LJ,McPherson B

更新日期：2021-01-11 00:00:00

abstract：:During the last third of the 20th century, pediatric otolaryngology became a defined specialty in many nations, resulting in focused training, fellowships, societies, journals, textbooks, etc. This development occurred as a result of an interaction between the changing sociological and economic status of the child and...

journal_title：Acta oto-laryngologica

authors： Ruben RJ

更新日期：2004-05-01 00:00:00

abstract：CONCLUSION:The necessity of considering cervical tuberculous lymphadenitis (CTL) should be emphasized even today for the differential diagnosis of cervical lymphadenopathy, particularly when it is located in the posterior triangle and supraclavicular regions even in patients without active pulmonary tuberculosis (PTB)....

journal_title：Acta oto-laryngologica

authors： Iguchi H,Wada T,Matsushita N,Teranishi Y,Yamane H

更新日期：2013-09-01 00:00:00

abstract：:Earlier investigation did not show any clear distinctive pathological features that differentiate vocal polyps from vocal nodules. The light microscopic distinctive features between the two lesions point in the direction of a more pronounced epithelial reaction and a more fibrous stromal change in vocal nodules. In th...

journal_title：Acta oto-laryngologica

authors： Kotby MN,Nassar AM,Seif EI,Helal EH,Saleh MM

更新日期：1988-05-01 00:00:00

abstract：:In this experimental study in the rat, compound 48/80--a potent degranulating drug of mast cells--was instilled in the external auditory meatus towards the tympanic membrane. Moreover, effusion material was produced in the attic space by blocking the tympanic isthmus with a piece of Gelfoam applied through the tympani...

journal_title：Acta oto-laryngologica

authors： Alm PE,Bloom GD,Hellström S,Salén B,Stenfors LE

更新日期：1982-11-01 00:00:00

abstract：:Assessment of hearing handicap is frequently based on hearing loss in the frequency region from 0.5 to 2.0 kHz. The region above 2 kHz, however, is important for hearing, particularly when one considers speech perception in conditions with ambient noise. The present study, based on 200 individuals (400 ears) with nois...

journal_title：Acta oto-laryngologica

authors： Smoorenburg GF

更新日期：1990-01-01 00:00:00

abstract：:The nasal mucosa and the autonomic nervous regulation of protective reflexes plays an important role for the protection of the lower airways. Increasing experimental evidence from both animal models and humans suggests that the organization of the autonomic nervous pathways is more complicated than previously assumed....

journal_title：Acta oto-laryngologica

authors： Anggård A

更新日期：1993-05-01 00:00:00