Gene silencing with siRNA targeting E6/E7 as a therapeutic intervention against head and neck cancer-containing HPV16 cell lines.

abstract：:The distribution of vascular endothelial growth factor (VEGF), one of the most important angiogenic factors, and microvessel density (MVD) were assessed in laryngeal carcinomas by means of immunohistochemistry. Correlation of VEGF with MVD and clinical parameters (T stage, N stage, histological grading, survival, recu...

journal_title：Acta oto-laryngologica

authors： Neuchrist C,Quint C,Pammer A,Burian M

更新日期：1999-01-01 00:00:00

abstract：CONCLUSIONS:Concurrent chemoradiotherapy with carboplatin and uracil-f tegafur (UFT) seems to be a promising and appropriate regimen for patients with poor performance status (PS) with locally advanced squamous cell carcinoma of the head and neck (SCCHN). OBJECTIVE:We designed a regimen based on divided low-dose admin...

journal_title：Acta oto-laryngologica

authors： Katori H,Tsukuda M,Taguchi T

更新日期：2007-10-01 00:00:00

abstract：CONCLUSION:Cochleostomy is the most efficient approach in delivering PEG-b-PCL polymersomes (PMs) to the inner ear. PMs can be delivered to the vestibule by transtympanic injection or cochleostomy. OBJECTIVE:To evaluate the efficiency of delivering PEG-b-PCL PMs into the inner ear using different approaches. METHODS:...

journal_title：Acta oto-laryngologica

authors： Zhang Y,Zhang W,Johnston AH,Newman TA,Pyykk I,Zou J

更新日期：2011-12-01 00:00:00

abstract：CONCLUSION:Salivary stones in the parotid gland that are not amenable to endoscopic extraction can safely be removed by a combined, endoscopic-external approach. OBJECTIVE:Limitations for endoscopic removability of salivary stones from the parotid gland are immobile stones in the deeper salivary duct system. A combine...

journal_title：Acta oto-laryngologica

authors： Mikolajczak S,Bremke M,Beutner D,Luers JC

更新日期：2015-01-01 00:00:00

abstract：:Five out of eight consecutive cases with initial symptoms of a 'midline granuloma' were identified as malignant histiocytosis (histiocytic sarcoma) which within 5 months to 4 years led to generalization and death. The three remaining cases also fulfilled the morphological criteria of this type of neoplasia, though the...

journal_title：Acta oto-laryngologica

authors： Laeng H,Gerber H,Mueller J

更新日期：1986-01-01 00:00:00

abstract：:The most common cause of seasonal allergic rhinitis in Japan is the Japanese cedar (JC). Recently, a pullulan-conjugated antigen (CS-560) has been developed to reduce adverse effects and to enhance the effect of JC-specific immunotherapy (IT). If the mechanism of IT can be fully elucidated and the treatment can be use...

journal_title：Acta oto-laryngologica

authors： Nakano A,Nakano K,Okawa T,Yamakoshi T,Terada N,Numata T,Konno A

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to demonstrate the long-term effectiveness of Expansion Sphincter Pharyngoplasty (ESP) as a standalone surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients through a prospective multi-center study. MATERIAL AND METHODS:A prospective non-com...

journal_title：Acta oto-laryngologica

authors： Plaza G,Baptista P,O'Connor-Reina C,Bosco G,Pérez-Martín N,Pang KP

更新日期：2019-02-01 00:00:00

abstract：CONCLUSIONS:This is the first report of mandibular reconstruction using the retroauricular (RA) or the modified face-lift (MFL) approach in head and neck cancer. This approach may have advantages over the conventional approach, especially in its superior aesthetic results. OBJECTIVE:The fibular osseous or osteocutaneo...

journal_title：Acta oto-laryngologica

authors： Kim WS,Jittreetat T,Nam W,Sannikorn P,Choi EC,Koh YW

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Li quick repositioning maneuver for treatment of geotropic horizontal canal benign paroxysmal positional vertigo (HC-BPPV) was reported in the literature. OBJECTIVE:The aim of this study is to observe the clinical efficacy of the Li quick repositioning maneuver for the treatment of geotropic HC-BPPV. METHO...

journal_title：Acta oto-laryngologica

authors： Li J,Zou S,Tian S

更新日期：2018-09-01 00:00:00

abstract：:The efflux of Na-24 was investigated in isolated labyrinths from a membrane section containing stria vascularis and spiral ligament in artificial endolymph medium. The efflux curves were calculated and compartmental analyses were made. The theoretical possibility of a exchange of sodium between compartments connected ...

journal_title：Acta oto-laryngologica

authors： Mnich Z

更新日期：1975-07-01 00:00:00

abstract：CONCLUSION:The Esteem(®) device proved to offer beneficial results in subjects suffering from high frequency, severe bilateral sensorineural hearing loss (SNHL) and may be considered as an alternative procedure to conventional hearing aids (HAs) or electroacoustic stimulation (EAS) systems. OBJECTIVES:Since the Esteem...

journal_title：Acta oto-laryngologica

authors： Barbara M,Biagini M,Monini S

更新日期：2011-04-01 00:00:00

abstract：:Preyer's reflex, the elicitation of startle response to auditory stimuli, has been widely used for the evaluation of hearing in rodents and other animals. Surprisingly, however, the sensitivity and specificity of Preyer's reflex in the assessment of hearing has not been adequately studied. The aim of this study was to...

journal_title：Acta oto-laryngologica

authors： Jero J,Coling DE,Lalwani AK

更新日期：2001-07-01 00:00:00

abstract：CONCLUSION:There is no increased risk of postoperative haemorrhage for abscess tonsillectomies in comparison to elective tonsillectomies. OBJECTIVE:There is still controversy as regards the optimal management of peritonsillar abscess. Opponents of tonsillectomy à chaud cite an increased postoperative bleeding risk. Mo...

journal_title：Acta oto-laryngologica

authors： Lehnerdt G,Senska K,Jahnke K,Fischer M

更新日期：2005-12-01 00:00:00

abstract：:Conclusions Endoscopic surgery is safe and effective for children with congenital basal meningoencephaloceles (CBMs); it provides an acceptable operative outcome with a short recovery time and fewer complications and may be considered as a primary approach. Objectives To explore the safety and effectiveness of using t...

journal_title：Acta oto-laryngologica

authors： Wu X,Zhang J,Zhang H,Xie Z,Fan R,Liu Y,Wu B,Sun H,Jiang W

更新日期：2016-06-01 00:00:00

abstract：CONCLUSION:After conventional curette adenoidectomy, a significant mass of residual adenoid tissue is observed in about 50% of the cases. The combined approach of conventional curette and endoscopic adenoidectomy with microdebrider assures a complete and accurate removal of the mass. It is an effective and safe method ...

journal_title：Acta oto-laryngologica

authors： Pagella F,Matti E,Colombo A,Giourgos G,Mira E

更新日期：2009-05-01 00:00:00

abstract：:In a previous study, the authors described a technique for recording ipsilateral EABRs using the DIGISONIC MXM cochlear implant (Gallégo et al, Acta Otolaryngol (Stockh) 1996; 116: 228-33) and showed that the EABR input/output functions were very similar across electrodes. In the present study a test of electrode func...

journal_title：Acta oto-laryngologica

authors： Gallégo S,Truy E,Morgon A,Collet L

更新日期：1997-03-01 00:00:00

abstract：:We investigated the redistribution of facial motor neurons after recovery from a crush injury of the facial nerve in the mongolian gerbil, with the retrograde transportation of horseradish peroxidase (HRP) technique. The facial nerve at the vertical segment was crushed unilaterally for 10 s with forceps. After 1 month...

journal_title：Acta oto-laryngologica

authors： Park HJ,Kim HN,Kim KM

更新日期：1995-03-01 00:00:00

abstract：:The aim of this study was to evaluate histologic changes after long-term administration of the topical nasal decongestants phenylephrine and oxymetazoline. Ninety healthy rabbits were divided into 3 groups for topical administration for 1 week, 2 weeks, and 4 weeks. Each group was subdivided into 3 subgroups by topica...

journal_title：Acta oto-laryngologica

authors： Suh SH,Chon KM,Min YG,Jeong CH,Hong SH

更新日期：1995-09-01 00:00:00

abstract：:The purpose of this study was to show the early stages of polyp formation, as part of our studies on the pathogenesis of nasal polyps. Two and 4 weeks after experimental tubal occlusion in 18 Wistar rats, 13 showed signs of bacterial infection, respective acute otitis media. In the majority of these rats polypouslike ...

journal_title：Acta oto-laryngologica

authors： Larsen PL,Tos M

更新日期：1991-01-01 00:00:00

abstract：:In a previous investigation into noise-induced hearing loss by comparing 2-month-old albino with pigmented guinea pigs, albinos displayed significantly greater shifts in cochlear microphonic (CM) threshold and less recovery than the pigmented animals 7 days after noise exposure. The present study compared the response...

journal_title：Acta oto-laryngologica

authors： Conlee JW,Abdul-Baqi KJ,McCandless GA,Creel DJ

更新日期：1988-07-01 00:00:00

abstract：:The present study on the anatomy of the human facial nerve is based on the results of a series of gross dissections, and histological and electro-diagnostic examinations. From our findings it follows that there is a definite spatial orientation of the peripheral branches in the facial nerve trunk. The results of the m...

journal_title：Acta oto-laryngologica

authors： Podvinec M,Pfaltz CR

更新日期：1976-03-01 00:00:00

abstract：:The practicability of recording auditory nerve and brainstem responses during early childhood is demonstrated. This paper reports our experience with two different electrode locations: ear-canal/ear-lobe and ear-lobe/vertex. The test is performed with a light portable stimulus-generating and response-recording system ...

journal_title：Acta oto-laryngologica

authors： Montandon PB,Cao MH,Engel RT,Grajew T

更新日期：1979-03-01 00:00:00

abstract：:An analysis of auditory brainstem response (ABR) thresholds and ABR-based frequency tuning curves was performed in 15 Sprague-Dawley rats exposed to Haemophilus influenzae type b endotoxin; 5 microg/50 microl toxin was instilled every second day, altogether five times, into the middle ear cavity through a small perfor...

journal_title：Acta oto-laryngologica

authors： Stenqvist M,Anniko M,Pettersson A

更新日期：1997-05-01 00:00:00

abstract：:The effects of two simulated hearing impairments (presbyacusis) on speech perception were investigated in two groups of normally hearing subjects (30 and 48 subjects, respectively). Eight patients with presbyacusis with similar hearing impairment to those in the latter simulation served as the clinical material. Word ...

journal_title：Acta oto-laryngologica

authors： Sorri M,Huttunen K,Körkkö P,Mäki-Torkko E

更新日期：2000-03-01 00:00:00

abstract：CONCLUSION:Mouse embryonic stem cells (ESCs) transplanted into the scala tympani are able to migrate in the cochlea of rats deafened with aminoglycoside and partly restore the structure of sensory epithelia of the inner ear. OBJECTIVES:To explore the migration and differentiation of enhanced green fluorescence protein...

journal_title：Acta oto-laryngologica

authors： Zhao LD,Li L,Wu N,Li DK,Ren LL,Guo WW,Sun JH,Liu HZ,Chen ZT,Xing GQ,Yang SM

更新日期：2013-02-01 00:00:00

abstract：:Seventeen cases of postinflammatory acquired artresia of the external auditory canal in 14 women are described and analysed. Fourteen of these cases were solid atresias in which the auditory canal was more or less filled with fibrous tissue. Three patients had partial membranous atresia. The aetiology was external oti...

journal_title：Acta oto-laryngologica

authors： Bonding P,Tos M

更新日期：1975-01-01 00:00:00

abstract：:Background: If the pulsatile tinnitus caused by sigmoid sinus diverticulum/dehiscence cannot be diagnosed and treated, it can lead to significant morbidity and mortality.Aim: To assess the sandwich surgical technique for sigmoid sinus wall reconstruction for the treatment of pulsatile tinnitus caused by sigmoid sinus ...

journal_title：Acta oto-laryngologica

authors： Sun J,Sun J

更新日期：2019-12-01 00:00:00

abstract：:Background: Odontogenic sinusitis (OS) is a common but underdiagnosed form of acute rhinosinusitis (ARS). OS carries no specific characteristics, but unilateral symptoms and certain microbiological as well as radiological findings indicate odontogenic origin. Aims/objectives: We studied the proportion of OS in ARS pat...

journal_title：Acta oto-laryngologica

authors： Wuokko-Landén A,Blomgren K,Välimaa H

更新日期：2019-09-01 00:00:00

abstract：:Gaze functions under high-frequency head oscillations with large amplitudes were investigated in 12 normal subjects. Oscillation amplitude decreased as the frequency increased (31 degrees at 2 Hz to 11 degrees at 5 Hz on average). Maximum head velocity and acceleration were 170-200 degrees/s and 2,500-5,000 degrees/s2...

journal_title：Acta oto-laryngologica

authors： Takahashi M,Akiyama I,Tsujita N

更新日期：1989-03-01 00:00:00

abstract：:Serum type (IgG, IgM and IgA-class) and secretory type antibodies specific to Streptococcus pneumoniae (Pn), Haemophilus influenzae (Hi) and Branhamella catarrhalis (Br) were measured by enzyme-linked immunosorbent assay (ELISA) in 46 serum and 114 middle ear effusion (MEE) samples from 85 children with acute otitis m...

journal_title：Acta oto-laryngologica

authors： Karjalainen H,Koskela M,Luotonen J,Herva E,Sipilä P

更新日期：1990-01-01 00:00:00