Abstract:
:Serum type (IgG, IgM and IgA-class) and secretory type antibodies specific to Streptococcus pneumoniae (Pn), Haemophilus influenzae (Hi) and Branhamella catarrhalis (Br) were measured by enzyme-linked immunosorbent assay (ELISA) in 46 serum and 114 middle ear effusion (MEE) samples from 85 children with acute otitis media (AOM). The samples were obtained within 12 h from the onset of the ear symptoms. Serum (but not secretory) type antibodies to the infecting Pn serotype were found in 24% of the MEE samples of the patients with Pn AOM and, correspondingly, serum and/or secretory type antibodies to Hi and Br were seen in 54% and 63% of the MEE samples of the patients with Hi or Br AOM, respectively. Moreover, antibodies against bacteria other than the causative one could also be found in the MEE. The occurrence of the serum type antibodies against these bacteria in the MEE was closely correlated with their serum levels. The findings of this study indicate that during the very early phase of AOM, the MEE contains both serum type antibodies originating from the serum, and secretory antibodies of middle ear origin. Among them there are antibodies specific to the three most common bacteria causing AOM (Pn, Hi, and Br) regardless of the bacterial etiology of the AOM attack in question.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Karjalainen H,Koskela M,Luotonen J,Herva E,Sipilä Pdoi
10.3109/00016489009107421subject
Has Abstractpub_date
1990-01-01 00:00:00pages
111-8issue
1-2eissn
0001-6489issn
1651-2251journal_volume
109pub_type
杂志文章abstract::This study correlates static and flow-cytometric analysis on paraffin-embedded and fresh material of salivary gland carcinomas. Nuclear suspensions for DNA analysis were prepared from paraffin-embedded and fresh material. Comparison of the results of static and flow cytometry on paraffin-embedded material revealed no ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950181080
更新日期:1999-01-01 00:00:00
abstract::It is well documented that quinine induces reversible hearing loss and tinnitus. The purpose in this study was to induce a quinine hearing loss and to investigate if verapamil, a Ca2+ channel antagonist of L-type might affect the response. Pigmented guinea pigs (n = 24) were anaesthetized by atropine. Hypnorm and mida...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709117990
更新日期:1997-01-01 00:00:00
abstract:CONCLUSION:The improved biocompatibility of Bioverit II coated with a nanostructured surface shows promising qualities for use in human reconstructive middle ear surgery. In the case of chitosan-hydroxyapatite composite prostheses, further investigations regarding composition of the material, degree of purity and desig...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480601053032
更新日期:2007-08-01 00:00:00
abstract::The input from fore- and hindlimbs to the vestibular nuclear complex (VNC) was investigated in awake cats. Electrical stimulus was given to the sciatic, radial and vestibular nerves bilaterally and single unit responses were recorded in the VNC with extracellular technique. The position of the microelectrode was histo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126395
更新日期:1979-01-01 00:00:00
abstract::Unilateral tubal occlusion was performed in 10 cats, which were sacrificed 26-44 months later. During the observation period repeated bilateral tympanometry and auditory nerve response were recorded. Paracentesis with evacuation of effusion was performed up to eight times and the effusion was examined by viscometry. A...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409132936
更新日期:1984-05-01 00:00:00
abstract::Primary afferent projections from singular parts of the vestibular labyrinth were studied in the guinea pig. The posterior ampullary nerve, the common trunk of the anterior and lateral ampullary nerves, as well as fibers innervating the macula sacculi or the macula utriculi were traced with crystals of horseradish per...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137430
更新日期:1992-01-01 00:00:00
abstract::The tonsils are mucosa-associated lymphoid organs. Several details regarding their normal function and pathological alteration are still unknown. In this review the relationship of the tonsils to similar lymphoid organs is discussed, the possibilities of antigen uptake (M cells and micropores of the crypt epithelium) ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:
更新日期:1987-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this prospective study was to analyze the effect of glasses and contact lenses on the latency and velocity of visually evoked saccadic eye movements. MATERIAL AND METHODS:A saccadic test was performed 10 times on 20 emmetropic controls (Group A) and 20 ametropic test subjects with myopia (Grou...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::The effects of transdermally administered scopolamine (TTS-scopolamine) (release rate 5 micrograms/h, one and two patches) and dimenhydrinate (100 mg) on caloric, angular acceleration induced and optokinetic nystagmus were examined in 16 volunteers in a randomized double-blind study. All drugs induced a statistically ...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016488509182266
更新日期:1985-05-01 00:00:00
abstract:CONCLUSIONS:The midfacial degloving approach is a favorable option for advanced sinonasal inverted papilloma with a fair recurrence rate, and can replace the lateral rhinotomy approach, which is considered too invasive for benign tumor due to its facial scar. OBJECTIVE:This study aimed to assess the treatment outcomes...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903311211
更新日期:2010-04-01 00:00:00
abstract::Laryngoscopy in cases of sulcus vocalis reveals bowed vocal folds, resulting in a spindle-shaped chink with glottal incompetence. The anatomic and functional problems and resulting incomplete glottal closure during phonation lead to the presenting symptoms of breathy hoarseness, decrease in maximum phonation time (MPT...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489.2014.999873
更新日期:2015-06-01 00:00:00
abstract:CONCLUSIONS:This study confirms a high prevalence of human papillomavirus (HPV)-positive tonsillar tumours (52%). The survival of the HPV-positive group was significantly better in males. OBJECTIVES:We assessed the prevalence of HPV in 137 patients with tonsillar carcinomas, measured the p53- and Ki-67-positive tumour...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903071377
更新日期:2010-02-01 00:00:00
abstract::The production of middle ear effusion by mechanical stimulation was studied in sympathectomized and vagotomized animals. Mechanical stimulation was obtained by a 14 degree C airstream in the external auditory canal. In sympathectomized animals this procedure caused effusion production and vasoconstriction of pars flac...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809107365
更新日期:1988-07-01 00:00:00
abstract::Blood circulation in the cochlear lateral wall after exposure to a non-physiological level of sound (120-125 dB SPL, 3 h) was investigated immunohistologically. Kanamycin (KM), which was expected to function as a tracer of blood flow, was administered to guinea pigs 5 min to 21 h after sound termination. At 5-30 min, ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137358
更新日期:1991-01-01 00:00:00
abstract::The embryonic development of the crista ampullaris of the CBA/CBA mouse was followed both in organ culture of explanted inner ears of the 16th gestational day and in vivo from the 16th gestational day until the 21st day, an age corresponding to birth. Cytodifferentiation of the sensory epithelium of the crista ampulla...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309132868
更新日期:1983-07-01 00:00:00
abstract::The sensory and secretory epithelia may become morphologically changed following the exposure to mercury chloride. The earliest and most sever change in the sensory epithelium appeared in the apical part of the cochlea, while the basal coils were only seldom damaged (cytocochleogram studies). Acute intoxication mostly...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809111928
更新日期:1978-03-01 00:00:00
abstract:OBJECTIVE:To investigate the hearing prognosis of idiopathic sudden sensorineural hearing loss (SSNHL) treated with different initial therapies. METHODS:Subjects consisted of patients diagnosed with idiopathic SSNHL within 7 days from onset and showing severe hearing loss (≥60 dB), who were registered in a Japanese mu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2017.1296970
更新日期:2017-01-01 00:00:00
abstract::The spiral ganglion from white cats with hereditary deafness has been studied with the transmission electron microscope, and comparisons made with hearing animals at different ages. Ganglion cell loss occurs secondary to destruction of the organ of Corti, but only after the lapse of several months. Prior to neuronal l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009131737
更新日期:1980-11-01 00:00:00
abstract:CONCLUSIONS:Flat-panel cone-beam computed tomography (CBCT) is able to assess the trajectory of the implanted cochlear implant (CI) array. This is essential to determine specific effects of electrode design and surgical innovations on outcomes in cochlear implantation. CBCT is a non-invasive approach yielding similar d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.644805
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To determine the clinical usefulness of the dichotic multiple-frequency (MF) auditory steady-state response (ASSR) technique for estimating normal hearing compared to a 0.5-kHz tone burst and broadband click auditory brainstem response (ABR) protocol in a sample of adults. MATERIAL AND METHODS:A comparative ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310015902
更新日期:2004-01-01 00:00:00
abstract::Basic scientific research has demonstrated that epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), platelet-derived growth factor-AA (PDGF-AA) and transforming growth factor-alpha (TGF-alpha) are induced by acute tympanic membrane (TM) perforation. The expression of these growth factors peaks during...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.1080/000164802320396259
更新日期:2002-09-01 00:00:00
abstract::Taking advantage of a natural experimental situation, we compared, retrospectively, functional results after nasalization and ethmoidectomy for diffuse nasal polyposis. Nasalization was a radical ethmoidectomy systematically removing all the bony lamellae and mucosa within the labyrinth, with large antrostomy, sphenoi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709113445
更新日期:1997-07-01 00:00:00
abstract::Aspartate and alanine aminotransferase (ASAT, ALAT) activities were measured in human post-mortem sera, cerebrospinal fluid (CSF), perilymph and endolymph. Due to heart and/or liver morbidity during a terminal illness, the ASAT and ALAT serum activities were considerably increased as compared with normal and both were...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609107478
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Li quick repositioning maneuver for treatment of geotropic horizontal canal benign paroxysmal positional vertigo (HC-BPPV) was reported in the literature. OBJECTIVE:The aim of this study is to observe the clinical efficacy of the Li quick repositioning maneuver for the treatment of geotropic HC-BPPV. METHO...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016489.2018.1476778
更新日期:2018-09-01 00:00:00
abstract::The correlation between allergen-induced specific and non-specific (histamine) nasal reactions was studied, especially as regards topical glucocorticosteroid effects on the non-specific reactions. Thirteen patients with strictly seasonal allergic rhinitis participated. A nasal challenge with histamine and three increa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127508
更新日期:1989-03-01 00:00:00
abstract::In order to study the connection between occupation and sinonasal cancer we have reviewed the files and histological sections of 70 patients (24 females and 46 males) treated at the Department of Oto-rhino-laryngology, National Hospital of Norway. Detailed information concerning previous occupations was obtained by te...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509119160
更新日期:1985-01-01 00:00:00
abstract::Dysphagia is a common presenting complaint in otolaryngology practice, and there are many causes. Forestier syndrome is a rare cause of dysphagia. It is also known as diffuse idiopathic skeletal hyperostosis (DISH) syndrome or vertebral ankylosing hyperostosis. Forestier syndrome consists of anterolateral perivertebra...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500504192
更新日期:2006-07-01 00:00:00
abstract::Cisplatin ototoxicity is known to involve mainly the organ of Corti. Outer hair cells (OHCs). especially in the basal turn, are preferentially involved. One possible mechanism of ototoxicity might be alteration of the antioxidant system causing an increase in free radicals. It has been demonstrated that heat shock pro...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000793
更新日期:2000-03-01 00:00:00
abstract:CONCLUSION:From aspect of fluid dynamics, expanding patients' nasopharyngeal coronal-sectional area to 48.3-54.7% of normal area will bring the airflow velocity back to normal in adenoidal hypertrophy children. It might provide a suggestion for adenoidectomy range selection and whether total resection is necessary. OB...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1212266
更新日期:2017-01-01 00:00:00
abstract::The occurrence of horizontal jerks with larger amplitudes than on Earth was observed during vertical optokinetic nystagmus in astronauts tested throughout a 7-day spaceflight. During early exposure to microgravity, a horizontal spontaneous-like nystagmus was recorded in darkness following both vertical and horizontal ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009107432
更新日期:1990-03-01 00:00:00