Abstract:
:The correlation between allergen-induced specific and non-specific (histamine) nasal reactions was studied, especially as regards topical glucocorticosteroid effects on the non-specific reactions. Thirteen patients with strictly seasonal allergic rhinitis participated. A nasal challenge with histamine and three increasing doses of allergen was performed on the first day. The patients were rechallenged 24 h later with the same histamine dose and the lowest allergen dose from the previous day. The same 2-day challenge was also performed after pretreatment for one week with budesonide in 8 of these patients. Symptom scores were recorded. The N-alpha-tosyl-L-arginine-methyl-esterase (TAME esterase) activity in nasal lavages was determined. The nasal symptoms and the TAME-esterase activity increased at rechallenge for both histamine and allergen, compared with the initial challenge. The mean ( +/- SE) composite nasal symptom score after histamine increased from 3.5 +/- 0.49 to 4.9 +/- 0.35 (p less than 0.01) and after allergen from 1.62 +/- 0.3 to 3.2 +/- 0.5 (p less than 0.01) at rechallenge. Similar increases were recorded for the TAME-esterase activity. A close correlation between the allergen-induced increase in specific (allergen) and non-specific (histamine) reactivity was found (r = 0.7, p less than 0.01, composite nasal symptom score). Treatment with topical glucocorticosteroids abolished the allergen-induced increase in both specific (p less than 0.001) and non-specific (histamine) (p less than 0.01) nasal reactivity.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Andersson M,Andersson P,Pipkorn Udoi
10.3109/00016488909127508subject
Has Abstractpub_date
1989-03-01 00:00:00pages
270-7issue
3-4eissn
0001-6489issn
1651-2251journal_volume
107pub_type
杂志文章abstract:OBJECTIVE:To determine factors influencing help-seeking behaviour in hearing-impaired persons aged > or = 55 years MATERIAL AND METHODS:The study comprised 1,419 persons (480 females, 939 males) aged > or = 55 years who participated voluntarily in a driving test. Pure-tone audiometry was performed in all subjects. Par...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/0001648031000719
更新日期:2003-09-01 00:00:00
abstract::The vascular pattern of the rat cochlea was demonstrated by the aid of Berlin Blue (Prussian Blue) contrast. The vascular anatomy is similar to other mammals. The infrequent occurrence of the vessel of the basilar membrane under the organ of Corti is interesting in respect to its presumed importance for the oxygen sup...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127102
更新日期:1980-01-01 00:00:00
abstract::Abstract Usage of the Vibrant Soundbridge (VSB) with round window (RW)-Coupler placement at the RW has been shown to successfully treat mixed hearing loss. Coupling between the VSB's floating mass transducer (FMT) and the RW membrane is difficult in the case of sclerosis in the RW and drilling down the bony lip unti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.649492
更新日期:2012-06-01 00:00:00
abstract:CONCLUSION:The amendments made to pre-existing transcanal approaches limit the possibility of extrusion of the electrode and reduce the time of 'blind' surgery. OBJECTIVE:Alternative techniques to classic mastoidectomy and posterior tympanotomy for cochlear implantation have already been described but their main drawb...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480902998299
更新日期:2010-01-01 00:00:00
abstract::Nasal polyps is a chronic inflammatory disease of the upper airway characterized by structural abnormalities including stromal fibrosis. Fibroblasts are a rich source of cytokines and inflammatory mediators and are thought to play an important role in the development of fibrosis. In addition, there is considerable evi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180478
更新日期:1999-01-01 00:00:00
abstract::The nasal mucosa and the autonomic nervous regulation of protective reflexes plays an important role for the protection of the lower airways. Increasing experimental evidence from both animal models and humans suggests that the organization of the autonomic nervous pathways is more complicated than previously assumed....
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489309135832
更新日期:1993-05-01 00:00:00
abstract::We investigated the postoperative conditions of ears and the hearing acuity of patients who underwent posterior canal wall reconstruction tympanoplasty for operated ears with open mastoid. The study included 118 ears of 105 patients (57 males, 48 females; age range 5-75 years) and the patients were followed for > 1 ye...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164802753648114
更新日期:2002-04-01 00:00:00
abstract::Biopsy samples from the maxillary sinus mucosa of patients with purulent, non-purulent and recurrent sinusitis were studied histologically and compared with those from a maxillary sinus of patients with no previous history of sinus disease on the side of sampling. Basement membrane thickening, atypical gland formation...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009107468
更新日期:1990-11-01 00:00:00
abstract::The results of myringoplasty on 172 ears examined after an average follow-up time of 1.5 years are reported. The fascial underlay technique with swing-door plasty was employed in 78% of the cases. The graft take was successful in 150 ears (87%), three of which (2%) later revealed adhesive changes in the middle ear. Th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130902
更新日期:1982-05-01 00:00:00
abstract:OBJECTIVE:Acquired centralized tinnitus (ACT) is the most frequent type of chronic tinnitus. We introduce a cognitive neurophysiological ACT hypothesis based on centralized cognitive sensitization processes. MATERIAL AND METHODS:Published cognitive sensitization processes were reviewed using PubMed. Furthermore, a Coc...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016333
更新日期:2004-05-01 00:00:00
abstract::Two speech processing schemes have been implemented on a real-time laboratory speech processor for speech perception studies on normal-hearing subjects. The first scheme presents the information of two spectral components, the first and second formant of the speech signal, and will be referred to as the ZC (zero-cross...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1990.12088420
更新日期:1990-01-01 00:00:00
abstract::An in vivo method for the study of mucociliary activity in the human trachea and bronchi is presented. The method is based on a two-way fibre-optic system whereby reflections of light emitted by one glass-fibre and reflected by the cilia are picked up by a second glass fibre and transmitted to a recording unit. The gl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135885
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the radiologic findings with histological results of anatomically matched whole organ sections and to analyze the accuracy of pretherapeutic radiologic staging of glottic cancers. METHODS:The histologic findings of surgical specimens of 30 patients who had undergone tota...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.562538
更新日期:2011-08-01 00:00:00
abstract:CONCLUSION:The psychometric characteristics of Standard-Chinese lexical neighborhood test (LNT) confirmed the lexical effects of the four word categories. The established normative baseline can be used in evaluating the word-recognition performance of the hearing-impaired listeners. OBJECTIVES:The purpose of the prese...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.3109/00016489.2013.840923
更新日期:2014-01-01 00:00:00
abstract::Two hundred Malaysian patients representing 227 ears with previously untreated cholesteatoma disease were analysed retrospectively in terms of i) type of disease, i.e. primary acquired attic defect or posterior superior retraction pocket and secondary acquired type cholesteatoma; ii) positive history of previous middl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138380
更新日期:1991-01-01 00:00:00
abstract::Substance P has been proved an important neurotransmitter and neuromodulator, serving not only as an excitatory transmitter of the first afferent synapse of pain pathways but as a valuable neuromodulator in the primary cortical areas of sensosensorial integration. In the human acoustic cortex, substance P has been fou...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127525
更新日期:1989-05-01 00:00:00
abstract:CONCLUSIONS:Gentamicin ototoxicity presents with gait imbalance and oscillopsia, but only rarely with hearing loss and vertigo. Sinusoidal rotational stimuli with high accelerations such as the bedside head-thrust test or rotational step changes in velocity are useful to diagnose bilateral vestibulopathy. OBJECTIVE:To...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600606673
更新日期:2006-10-01 00:00:00
abstract::Background: Chronic exposure to whole body vibration can affect the gastrointestinal system, the lumbar spine, the peripheral veins and the vestibulocochlear system. Aims/Objectives: The aim of this study was to evaluate the effects of vibration on the vestibular system in noisy and noise-free environments using the v...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1666213
更新日期:2019-11-01 00:00:00
abstract::Several reports have indicated that some cochlear implant patients experience a reduction in their tinnitus while listening to noise or speech. In the present study, two patients reporting bilateral tinnitus were selected from a group of adults with the Nucleus cochlear implant. They rated their tinnitus loudness and ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135811
更新日期:1993-05-01 00:00:00
abstract:CONCLUSION:The curative effect in the group where facial-facial anastomosis (FFA) was delayed for 7 days was similar to that in the immediate FFA group and had a better repair within 60 days. OBJECTIVE:Due to the uncertainty about optimal timing of delayed facial nerve repair, we designed an experimental study in guin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.765967
更新日期:2013-07-01 00:00:00
abstract::A 50-year-old woman presented with a 10-year history of swelling of the left cheek during and after meals. She regularly pushed the cheek hard to decrease the swelling by excreting the saliva. She did not have pain or fever. She also complained of bronchial asthma and allergic rhinitis. Magnetic resonance imaging (MRI...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600621680
更新日期:2006-10-01 00:00:00
abstract::Mucormycosis is a rare acute fatal fungal infection. It is typically observed in diabetic or immunocompromised patients but not in systemically healthy individuals. Here, we describe an unusual mucormycosis case in an immunocompetent patient who had clinical signs of a maxillary sinusitis and associated osteomyelitis ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500534439
更新日期:2006-09-01 00:00:00
abstract:CONCLUSION:This study demonstrated that treatment with montelukast in combination with levocetirizine may have a beneficial effect on clinical improvement of middle ear fluid in children with otitis media with effusion (OME). OBJECTIVE:To evaluate the effect of the combination of montelukast and levocetirizine on shor...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,随机对照试验
doi:10.3109/00016489.2013.824113
更新日期:2013-12-01 00:00:00
abstract::Background: Lermoyez syndrome (LS) is a rare auditory disorder, the details of LS remain unclear.Objectives: To investigate the grades of endolymphatic hydrops (ELH) and clinical characteristics of clinically diagnosed LS.Material and methods: Nine patients with clinically diagnosed LS were included. three-dimensional...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1751275
更新日期:2020-07-01 00:00:00
abstract::As a continuation of our previous work, where we have demonstrated that in chronic otitis media the picture in the submucosa-bone marginal zone is dominated by capillary proliferation and occurrence of a mononuclear, histiocyte-like cell containing lysosome-like cytoplasmatic bodies, we now report the presence of cons...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509124704
更新日期:1975-05-01 00:00:00
abstract:CONCLUSIONS:Our preliminary results indicate that mastoidectomy by reconstruction of the posterior wall and obliteration (MAPRO) avoided the disadvantages of a canal-wall-down mastoidectomy. MAPRO effectively prevented cholesteatoma recurrence, provided an excellent basis for hearing restoration, and was generally wate...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.643456
更新日期:2012-04-01 00:00:00
abstract::The submucosal glands in the rat nose are characterized by the presence of both neutral and acid glycoproteins, which are important constituents of nasal and tracheobronchial secretions. This study is an attempt to gain a better insight into the secretion of these two types of glycoproteins and its neural regulation. ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709128287
更新日期:1987-11-01 00:00:00
abstract:OBJECTIVE:To determine the clinical usefulness of the dichotic multiple-frequency (MF) auditory steady-state response (ASSR) technique for estimating normal hearing compared to a 0.5-kHz tone burst and broadband click auditory brainstem response (ABR) protocol in a sample of adults. MATERIAL AND METHODS:A comparative ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310015902
更新日期:2004-01-01 00:00:00
abstract::The vestibulo-ocular reflex (VOR) of the alert rhesus monkey was studied using rotational acceleration in the horizontal plane. Both sinusoidal and pseudorandom binary sequence (PRBS) stimuli were used to perform parameters. Results from sinusoidal studies over the frequency range 0.01 to 1.28 Hz, with stimulus amplit...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130856
更新日期:1982-01-01 00:00:00
abstract::The objective of this study was to develop and test an endolabyrinthic microsurgical procedure for treatment of vertigo, the utriculostomy. This involves the application of local heat for obtaining a fistula in the membranous labyrinth, so as to establish communication between the endolymphatic and perilymphatic space...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180739
更新日期:1999-01-01 00:00:00