Abstract:
:Taking advantage of a natural experimental situation, we compared, retrospectively, functional results after nasalization and ethmoidectomy for diffuse nasal polyposis. Nasalization was a radical ethmoidectomy systematically removing all the bony lamellae and mucosa within the labyrinth, with large antrostomy, sphenoidotomy, frontotomy, and middle turbinectomy (Surgeon 1, 39 consecutive patients operated on between March and September 1991). Ethmoidectomy was a less systematic procedure, that was adapted to the extent of the pathology (Surgeon 2, 37 consecutive patients, operated on between October 1991 and November 1994). In May 1994, a third physician mailed a questionnaire simultaneously to all patients including 10-point visual analog scales 34/39 patients in the nasalization group (age: 28-71 years: 20 asthmatics; follow-up: 32-36 months), and 29/37 patients in the ethmoidectomy group (age: 26-65 years: 9 asthmatics: follow-up: 18-31 months) participated in the study. The overall nasal improvement was 8.8 +/- 0.2 (mean +/- SEM) after nasalization and 5.9 +/- 0.6 after ethmoidectomy (p = 0.0001). Olfaction improvement was similar in both groups 6 months after surgery, remained at the same level 36 months after nasalization (6.9 +/- 0.7), but decreased to 4.2 +/- 1 points 24 months after ethmoidectomy (p = 0.02). Asthma improvement remained significantly better after nasalization (p = 0.05), and the need for systemic steroids was also lower (p = 0.03). Results of this study suggest that when dealing with nasal polyposis, the more radical the surgery, the better the functional results.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Jankowski R,Pigret D,Decroocq Fdoi
10.3109/00016489709113445subject
Has Abstractpub_date
1997-07-01 00:00:00pages
601-8issue
4eissn
0001-6489issn
1651-2251journal_volume
117pub_type
杂志文章abstract::The penetration of oral erythromycin stearate (Abboticin), administered in a dosage of 500 mg three times a day, into the maxillary sinus mucosa and secretion was studied in 15 patients (22 sinuses) operated on for chronic maxillary sinusitis. The average concentration in serum was 2.3 microgram/ml, 1.2 microgram/ml i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123970
更新日期:1977-09-01 00:00:00
abstract::Normal human subjects were exposed to repeated optokinetic afternystagmus (OKAN) testing in either one direction or alternating directions of stripe movement. Sessions were conducted at intervals of either one week or several weeks. Repeated exposure to OKAN stimulation in one direction produced significant response d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509119150
更新日期:1985-01-01 00:00:00
abstract::The results of myringoplasty on 172 ears examined after an average follow-up time of 1.5 years are reported. The fascial underlay technique with swing-door plasty was employed in 78% of the cases. The graft take was successful in 150 ears (87%), three of which (2%) later revealed adhesive changes in the middle ear. Th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130902
更新日期:1982-05-01 00:00:00
abstract:CONCLUSION:This study described objective and subjective evaluations of the Nurotron® Venus™ Cochlear Implant System and indicated that this system produced a satisfactory performance. OBJECTIVE:To observe the performance of the Nurotron® Venus™ cochlear implant (CI) system via electrophysiological and psychophysical ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1086022
更新日期:2016-01-01 00:00:00
abstract::Cochlear blood flow is considered to be closely related to cochlear function. Among several etiologic factors implicated in inner ear diseases, disturbance of local blood flow is held to be one of the most important. With this in view, various pharmaceuticals are currently being used to increase local blood flow in pa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137500
更新日期:1992-11-01 00:00:00
abstract:CONCLUSIONS:Local administration of MP delivered by the C/GP-MP-hydrogel can improve the recovery of facial nerve following crush injury. The findings suggested that locally injected MP delivered by C/GP-hydrogel might be a promising treatment for facial nerve damage. OBJECTIVES:In this study, the aim is to assess the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract::Six profoundly deaf patients were studied with mapping evoked potentials (MEP) using an acoustic signal passed through the vibrotactile prosthesis. This stimulus produced an activation of the central sulcus brain cortex. When the proSthesis was placed in the presenternal area it showed N1 P1 potentials with higher vol...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709117771
更新日期:1997-03-01 00:00:00
abstract::To elucidate the effects of CO2 in the middle ear upon the cochlea, measurements were made of the cochlear potentials (compound action potential and endocochlear potential) and of the pH of the inner ear fluids and the organ of Corti. Gas containing CO2 did not affect the AP threshold, except for a slight decrease in ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909107397
更新日期:1989-07-01 00:00:00
abstract::The submucosal glands in the rat nose are characterized by the presence of both neutral and acid glycoproteins, which are important constituents of nasal and tracheobronchial secretions. This study is an attempt to gain a better insight into the secretion of these two types of glycoproteins and its neural regulation. ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709128287
更新日期:1987-11-01 00:00:00
abstract:CONCLUSION:The existence of patients with positive non-sentinel node indicates a risk of misdiagnosis of metastasis in oropharyngeal and oral cancer. OBJECTIVES:We attempted to confirm the usefulness of sentinel lymph node biopsy (SLNB) in oropharyngeal and oral cavity cancer to detect clinically occult metastases. P...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480801891710
更新日期:2008-10-01 00:00:00
abstract:CONCLUSION:Nasal obstruction, rhinorrhea, and the amount of rhinorrhea that confidently reflect the parasympathetic stimulation can be used to more precisely predict nonspecific nasal hyper-reactivity (NHR). OBJECTIVE:We aimed to identify factors that confidently reflected the presence and the degree of NHR, measured ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.681798
更新日期:2012-10-01 00:00:00
abstract:CONCLUSIONS:The results of this study confirm that both smoking of tobacco and alcohol consumption are risk factors for oral and oropharyngeal squamous cell carcinoma (OOSCC). The use of moist snuff had no effect on the risk of OOSCC, probably due to the low levels of tobacco-specific N-nitrosamines in Swedish moist sn...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510043440
更新日期:2005-09-01 00:00:00
abstract::An in vivo method for the study of mucociliary activity in the human trachea and bronchi is presented. The method is based on a two-way fibre-optic system whereby reflections of light emitted by one glass-fibre and reflected by the cilia are picked up by a second glass fibre and transmitted to a recording unit. The gl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135885
更新日期:1993-09-01 00:00:00
abstract::The expression of vascular cell adhesion molecule-1 (VCAM-1), alpha4-integrin and L-selectin was dynamically observed using an immunohistochemical approach during labyrinthitis induced by inoculation of keyhole limpet hemocyanin into the scala tympani of animals that had been systemically sensitized to it. At the same...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000414
更新日期:2000-08-01 00:00:00
abstract:CONCLUSION:Endoscopic surgery improved facial pain/headache and physical-psychosocial impacts in patients with nasal polyposis. However, one fifth of patients still experienced residual pain after surgery, requiring neurologic counseling to look for the non-sinonasal cause of their symptoms. OBJECTIVE:Considering the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1058531
更新日期:2015-01-01 00:00:00
abstract::We previously reported that long-term exposure to glutamate (Glu) induced death of cochlear outer hair cells (OHCs). However, the mechanisms of OHC death induced by Glu were unclear. In the central nervous system, Glu is known to interfere with a cystine-Glu antiporter, leading to a decrease in cystine uptake and redu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180612
更新日期:1999-01-01 00:00:00
abstract::683 tumour fragments from 63 head and neck carcinoma patients were cultured in vitro. Two laryngeal carcinomas and two salivary gland carcinomas were established into permanent cell lines. Malignancy of these cultured cells was proved by cloning, by chromosomal analysis and by transplantation into athymic (nu/nu) mice...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309130956
更新日期:1983-03-01 00:00:00
abstract:CONCLUSION:Chronic subjective dizziness (CSD) is frequent and affects twice as many women as men. Anxiety is a strong predisposing factor. The pathophysiologic concept of this disorder assumes that balance function and emotion share common neurologic pathways, which might explain that the balance disorder can provoke f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701805455
更新日期:2008-10-01 00:00:00
abstract::There is evidence that GABA acts as the excitatory neurotransmitter at synapses between vestibular hair cells and the afferent fibres in the mammalian labyrinth. The question arose as to whether certain vestibular dysfunctions such as labyrinthine vertigo could be treated in patients by influencing the peripheral GABA...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130882
更新日期:1982-01-01 00:00:00
abstract:CONCLUSION:There is no increased risk of postoperative haemorrhage for abscess tonsillectomies in comparison to elective tonsillectomies. OBJECTIVE:There is still controversy as regards the optimal management of peritonsillar abscess. Opponents of tonsillectomy à chaud cite an increased postoperative bleeding risk. Mo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510012336
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:The balloon catheter has been used for a decade to dilate paranasal sinus outflow tracts. The question is: how wide and how durable is the dilation of drainage pathways in patients in long-term observations after this procedure? OBJECTIVE:The objective of our study was to observe the changes occurring in th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1300941
更新日期:2017-09-01 00:00:00
abstract::Histology, histogenesis, biology and treatment of the rare spindle cell carcinoma of the larynx are presented. The histogenesis of spindle cell tumours has been much debated, but electron microscopic investigations have shown that most of the laryngeal lesions are squamous epithelial carcinomas that have undergone tra...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107550
更新日期:1984-07-01 00:00:00
abstract:BACKGROUND:Posterior tympanotomy (PT) is an important step in cochlear implant (CI) surgery, as it is the main access to the round window. Some CI candidates, especially children, may have concomitant otitis media with effusion (OME) which may result in technical issues during PT. There is still a debate whether to wai...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1813905
更新日期:2021-01-01 00:00:00
abstract::45CaCl2 was injected into gerbils in single or multiple doses, and the resulting radioactivity in serum, otoconial CaCO3, bone samples, and selected labyrinthine epithelium was determined by liquid scintillation spectrometry. Incorporation into both utricular and saccular otoconia occurred at the rate of 0.06-0.07 nmo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121327
更新日期:1975-09-01 00:00:00
abstract::In experiments on 11 dogs, the authors attempted to develop a method for avoiding serious complications following simultaneous bilateral radical neck dissection. Both internal jugular veins were resected; one vein was reconstructed with the autologous v. femoralis. Blood flow in the reconstructed vein was normal in th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409132914
更新日期:1984-05-01 00:00:00
abstract::Explants of stria vascularis and spiral ligament of guinea pig cochlea were kept in primary culture. On the explant, proliferating marginal cells advanced by 15 microns/day, suggesting that in vivo defects of the strial epithelium can be covered by new marginal cells. The marginal cells growing in the cell culture dis...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137471
更新日期:1992-09-01 00:00:00
abstract::Hereditary angioneurotic edema (HAE) is an autosomal dominant disease resulting from a deficiency of functional C1-esterase inhibitor. If not recognized promptly and treated properly the disease can result in a fatal outcome as it causes laryngeal edema, which can lead to a life-threatening acute upper airway obstruct...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510038185
更新日期:2005-11-01 00:00:00
abstract:HYPOTHESIS:To examine the cellular events following induced superficial lesions of the human tympanic membrane (TM). Such information could lead to enhanced appreciation of repair mechanisms and novel strategies to restore TM perforations. BACKGROUND:Persistent perforation of the TM in chronic otitis media is a major ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1321139
更新日期:2017-09-01 00:00:00
abstract::The electromagnetic interference of the recently introduced bone-anchored hearing aid (BAHA) model "BAHA Compact" by digital cellular phones is investigated and compared with that of the older "BAHA Classic 300" model. Measurements with two different digital cellular phones in a laboratory setting indicated that the n...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480260092318
更新日期:2002-07-01 00:00:00
abstract:CONCLUSION:We demonstrated an early increase in aquaporin 2 (AQP2) expression in a motor nerve (extratemporal facial nerve, FN) following acute peripheral compression (crush), concomitant to effective development of motor dysfunction (facial palsy). The early increase in AQP2 expression that occurred concomitantly with...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1010104
更新日期:2015-07-01 00:00:00