Head and neck carcinoma models. In vivo reproduction in athymic mice and in vitro culture.

abstract：BACKGROUND:Traumatic tympanic membrane perforation (TTMP) is usually managed conservatively because most close spontaneously within a few months. Nevertheless, spontaneous closure of TTMP during long-term observation has not been well described in the literature. OBJECTIVES:The present study investigated factors assoc...

journal_title：Acta oto-laryngologica

authors： Tachibana T,Kariya S,Orita Y,Makino T,Haruna T,Matsuyama Y,Komatsubara Y,Naoi Y,Nakada M,Noda Y,Sato Y,Nishizaki K

更新日期：2019-06-01 00:00:00

abstract：:Middle ear lesions were produced in chinchillas by introducing fascia, Gelfoam, silastic or a combination of these materials into the labyrinthine and mastoid bullae. After 1-2 months, conventional 226 Hz and multifrequency tympanometry (MFT) were performed and the animals were sacrificed for histopathological analysi...

journal_title：Acta oto-laryngologica

authors： Margolis RH,Schachern PL,Fulton S

更新日期：1998-03-01 00:00:00

abstract：:Anaesthesia and sedation in electrocochleo-graphy are of paramount importance for the whole procedure, since restlessness of the patient during the measurements can invalidate the results of the test. The time needed for extensive electrocochleography amounts on average to two hours. The only pain experienced during t...

journal_title：Acta oto-laryngologica

authors： Zvonar M,Zvonar-Kuhndl B,Odenthal DW

更新日期：1974-01-01 00:00:00

abstract：:The early development of human otoconial membranes was studied by scanning electron microscopy and X-ray microanalysis; 87 specimens, ranging from 7 to 12 weeks gestational age were examined. A few otoconia, which contained calcium, were present in the utricle by the end of the seventh week. By 8 weeks, both the saccu...

journal_title：Acta oto-laryngologica

authors： Wright CG,Hubbard DG

更新日期：1982-07-01 00:00:00

abstract：:We examined the serial changes of intravenously applied dye leakage and preliminary examined histamine release into nasal lavage fluid after topical stimulation with capsaicin in guinea pigs. A significant increase in the dye leakage response was detected for 30-40 min, with the maximum response occurring between 5 an...

journal_title：Acta oto-laryngologica

authors： Asakura K,Shirasaki H,Narita S,Kojima T,Kataura A

更新日期：1992-01-01 00:00:00

abstract：:Dysphagia is a common presenting complaint in otolaryngology practice, and there are many causes. Forestier syndrome is a rare cause of dysphagia. It is also known as diffuse idiopathic skeletal hyperostosis (DISH) syndrome or vertebral ankylosing hyperostosis. Forestier syndrome consists of anterolateral perivertebra...

journal_title：Acta oto-laryngologica

authors： Aydin E,Akdogan V,Akkuzu B,Kirbaş I,Ozgirgin ON

更新日期：2006-07-01 00:00:00

abstract：CONCLUSION:This study described objective and subjective evaluations of the Nurotron® Venus™ Cochlear Implant System and indicated that this system produced a satisfactory performance. OBJECTIVE:To observe the performance of the Nurotron® Venus™ cochlear implant (CI) system via electrophysiological and psychophysical ...

journal_title：Acta oto-laryngologica

authors： Gao N,Xu XD,Chi FL,Zeng FG,Fu QJ,Jia XH,Yin YB,Ping LC,Kang HY,Feng HH,Wu YZ,Jiang Y

更新日期：2016-01-01 00:00:00

abstract：:Spiral ganglia of guinea pig and mouse were investigated by scanning electron microscopy (SEM). The cochlea was freeze-fractured and then macerated with 0.1% OsO4 solution for 70-90 h (A-O-D-O method (1]. This allowed three-dimensional observation of the general view of the spiral ganglion and the intracellular struct...

journal_title：Acta oto-laryngologica

authors： Harada Y,Nagasawa A,Takumida M,Tagashira N,Hirakawa K,Suzuki M

更新日期：1989-05-01 00:00:00

abstract：CONCLUSION:Younger children tend to harbor more resistant strains because they are exposed to these pathogens more often through contacts with siblings or attendance at day-care centers and are frequently treated with antibiotics. The high prevalence of BLNAR strains should be taken into account in the treatment of AOM...

journal_title：Acta oto-laryngologica

authors： Sakai A,Hotomi M,Billal DS,Yamauchi K,Shimada J,Tamura S,Fujihara K,Yamanaka N

更新日期：2005-02-01 00:00:00

abstract：:The object of this study was to assess the contributions of various cranial nerve nuclei to the short latency vestibular evoked potentials (VsEPs) in cat. The following nuclei were investigated: vestibular nuclei, and 3rd, 6th and 10th cranial nerve nuclei. In unilateral labyrinthectomized cats, suboccipital craniecto...

journal_title：Acta oto-laryngologica

authors： Elidan J,Li G,Sohmer H

更新日期：1995-03-01 00:00:00

abstract：:Overexpression of epidermal growth factor receptor (EGF-R) is a common characteristic of epidermoid tumors and its expression in head and neck squamous cell carcinoma biopsies and cell lines has been reported previously by several authors. With the aim to provide more structural and functional details about the protei...

journal_title：Acta oto-laryngologica

authors： Bujía J,Wustrow TP

更新日期：1993-11-01 00:00:00

abstract：:Specimens from the epithelium on the lateral wall of the human nose were examined under the electron microscope using a lipid and carbohydrate retaining method. In many of the ciliated epithelial cells and in some of the cells in the mucosal glands we identified multilamellated granules. These structures resembled lam...

journal_title：Acta oto-laryngologica

authors： Svane-Knudsen V,Rasmussen G,Clausen PP

更新日期：1990-03-01 00:00:00

abstract：CONCLUSION:The addition of transoral robotic surgery (TORS) in the diagnostic management of patients classified with head and neck squamous cell carcinoma of unknown primary (SCCUP) is promising and appears to improve detection rates of the primary tumour. The approach presented in this first Scandinavian study could p...

journal_title：Acta oto-laryngologica

authors： Channir HI,Rubek N,Nielsen HU,Kiss K,Charabi BW,Lajer CB,von Buchwald C

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...

journal_title：Acta oto-laryngologica

authors： Chelikh L,Teixeira M,Martin C,Sterkers O,Ferrary E,Couloigner V

更新日期：2003-01-01 00:00:00

abstract：:Normal human subjects were exposed to repeated optokinetic afternystagmus (OKAN) testing in either one direction or alternating directions of stripe movement. Sessions were conducted at intervals of either one week or several weeks. Repeated exposure to OKAN stimulation in one direction produced significant response d...

journal_title：Acta oto-laryngologica

authors： Jell RM,Ireland DJ,Lafortune S

更新日期：1985-01-01 00:00:00

abstract：:Histology, histogenesis, biology and treatment of the rare spindle cell carcinoma of the larynx are presented. The histogenesis of spindle cell tumours has been much debated, but electron microscopic investigations have shown that most of the laryngeal lesions are squamous epithelial carcinomas that have undergone tra...

journal_title：Acta oto-laryngologica

authors： Katholm M,Krogdahl A,Hainau B,Bretlau P

更新日期：1984-07-01 00:00:00

abstract：:The present morphological study was designed to investigate the expression of HLA class II subregion gene products on human trachea. Frozen sections from the tracheas of 20 cadavers not suffering from ear, nose or throat diseases were studied immunohistochemically using monoclonal antibodies which recognize monomorphi...

journal_title：Acta oto-laryngologica

authors： Bujia J,Wilmes E,Hammer C,Kastenbauer E

更新日期：1990-07-01 00:00:00

abstract：:The aim of the present study is to construct a reference model with the indication for the attitude, the requirements and the resources needed in order to be able to deal with deafness in the presence of disabilities or associated problems. The study group consisted of 13 adults and 18 children affected by profound de...

journal_title：Acta oto-laryngologica

authors： Filipo,Bosco,Mancini,Ballantyne

更新日期：2004-04-01 00:00:00

abstract：:Histological measures of cochlear vasculature and blood flow were examined in 20 guinea pigs. Sixteen were exposed to octave band noise at 120 dB SPL for 30 min and then permitted to survive after the exposure for 6 h, 18 h, 48 h, or 4 weeks (N = 4 in each group). Control animals were exposed to the laboratory and app...

journal_title：Acta oto-laryngologica

authors： Dengerink H,Miller J,Axelsson A,Vertes D,Van Dalfsen P

更新日期：1985-07-01 00:00:00

abstract：:Background: Intratympanic and intravenous gadolinium administration is used to visualise endolymphatic hydrops. Aims/objectives: The goal of this study was to compare the image quality between intratympanic (IT-method) and intravenous (IV-method) gadolinium administration using three-dimensional inversion recovery wit...

journal_title：Acta oto-laryngologica

authors： Li Y,Sha Y,Wang F,Lu P,Liu X,Sheng Y,Zhang Z,Liu M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To investigate the hearing prognosis of idiopathic sudden sensorineural hearing loss (SSNHL) treated with different initial therapies. METHODS:Subjects consisted of patients diagnosed with idiopathic SSNHL within 7 days from onset and showing severe hearing loss (≥60 dB), who were registered in a Japanese mu...

journal_title：Acta oto-laryngologica

authors： Okada M,Hato N,Nishio SY,Kitoh R,Ogawa K,Kanzaki S,Sone M,Fukuda S,Hara A,Ikezono T,Ishikawa K,Iwasaki S,Kaga K,Kakehata S,Matsubara A,Matsunaga T,Murata T,Naito Y,Nakagawa T,Nishizaki K,Noguchi Y,Sano H,Sato

更新日期：2017-01-01 00:00:00

abstract：CONCLUSION:The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different s...

journal_title：Acta oto-laryngologica

authors： Chuang LP,Chen NH,Li HY,Lin SW,Chou YT,Wang CJ,Liao YF,Tsai YH

更新日期：2009-12-01 00:00:00

abstract：:Tumour growth of vestibular schwannomas is still difficult to predict. The aim of our study was to determine whether any defined histopathological feature was correlated with the clinical course. We did a retrospective study with 69 paraffin-embedded tumours to establish whether the number of vessels, blood cells extr...

journal_title：Acta oto-laryngologica

authors： Labit-Bouvier C,Crebassa B,Bouvier C,Andrac-Meyer L,Magnan J,Charpin C

更新日期：2000-10-01 00:00:00

abstract：:Intracellular calcium concentrations ([Ca2+]i) in type I cochlear spiral ganglion cells (SGCs) of the guinea pig were measured by digital imaging microscopy and the Ca(2+)-sensitive dye Fura-2. Extracellular ATP induced elevation of [Ca2+]i in type I SGCs in a concentration-dependent manner. The ATP-induced elevation ...

journal_title：Acta oto-laryngologica

authors： Cho H,Harada N,Yamashita T

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:pH monitoring can reflect the changes in H+ in the airway. OBJECTIVES:To explore the utility of pharyngeal pH monitoring in the diagnosis of laryngopharyngeal reflux disease (LPRD). MATERIAL AND METHODS:Clinical data from 956 suspected LPRD patients from February 2016 to March 2018 were analyzed retrospect...

journal_title：Acta oto-laryngologica

authors： Wang G,Qu C,Wang L,Liu H,Han H,Xu B,Zhou Y,Li B,Zhang Y,Sun Z,Gong J,Li L,Wu W

更新日期：2019-03-01 00:00:00

abstract：:Patients with chronic otitis media (COM) were divided into two groups, one to be given Cephalexin (CEX) orally and the other to be given CEX ear drops locally. The counts of viable bacteria in otorrheal samples collected before and after CEX administration were determined. The incidence of decrease in the count of bac...

journal_title：Acta oto-laryngologica

authors： Sugiyama M,Tanabe K,Chang KC,Nakai Y

更新日期：1981-09-01 00:00:00

abstract：:Synthesis of prostaglandins (PGs) was characterized in the lateral wall (LW) of guinea-pig cochlea. Basal synthesis at 37 degrees C was about 480 pg/LW (12.8 ng X mg-1 protein) for PGI2 and 85 pg/LW (2.3 ng X mg-1 protein) for PGE2, levelling out after 10 min of incubation. Incubation with arachidonic acid (10(-5) M) ...

journal_title：Acta oto-laryngologica

authors： Tran Ba Huy P,Ferrary E,Escoubet B,Sterkers O

更新日期：1987-05-01 00:00:00

abstract：:The goal of this investigation was to develop a method of surgical removal of the semicircular canals of the rabbit without induction of auditory impairment. Four different surgical techniques were utilized: i) fenestration of the lateral semicircular canal; ii) fibrin glue perfusion of the canal following fenestratio...

journal_title：Acta oto-laryngologica

authors： Gjuric M,Wigand ME,Hosemann W

更新日期：1992-11-01 00:00:00

abstract：:The influence of posture on nasal cavity geometry was studied by acoustic rhinometry in 14 normal adult subjects. On adopting a supine position from sitting the volume of the initially more patulous nasal cavity decreased and the volume of the less patulous side increased. These changes in volume are statistically sig...

journal_title：Acta oto-laryngologica

authors： O'Flynn P

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Intratympanic corticosteroid (IC), intravenous batroxobin (IB) as the treatment for sudden sensorineural hearing loss (SSNHL) has been reported. However, the data on combination therapy (CT) was scarce. OBJECTIVE:The aim of this retrospective study was to compare the efficacy of IC, IB, and CT in the treatm...

journal_title：Acta oto-laryngologica

authors： Jia H,Yu Z,Li X,Wang J,Ge X,Chen ZT,Huang X,Wei Y

更新日期：2019-06-01 00:00:00