Utility of 24-hour pharyngeal pH monitoring and clinical feature in laryngopharyngeal reflux disease.

Abstract:

BACKGROUND:pH monitoring can reflect the changes in H+ in the airway. OBJECTIVES:To explore the utility of pharyngeal pH monitoring in the diagnosis of laryngopharyngeal reflux disease (LPRD). MATERIAL AND METHODS:Clinical data from 956 suspected LPRD patients from February 2016 to March 2018 were analyzed retrospectively. RESULTS:One hundred forty-one patients had positive Ryan score. The positive rates of reflux symptom index (RSI), reflux finding score (RFS), RSI and RFS and RSI or RFS were 14.7%, 32.5%, 21.9%, 7.8% and 46.5%, respectively. The RFS in the positive Ryan score group was higher than that in the negative Ryan score group [(6 ± 3.5) vs. (4.8 ± 2.9)], while the RSI was not significantly different from that in the negative Ryan score group [(10.9 ± 8) vs. (11.3 ± 7.1)]. Regarding Ryan score as the gold standard in the diagnosis of LPRD, the sensitivity, specificity, positive and negative predictive value of identifying LPRD by RSI/RFS were 15.9%, 86.3%, 50.4% and 54%, respectively. CONCLUSIONS:Ryan score, RSI and RFS have poor correlation in detecting LPRD. Some patients may be missed with the Ryan score as a diagnostic criterion. SIGNIFICANCE:Pharyngeal pH monitoring is useful and more appropriate index is expected.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Wang G,Qu C,Wang L,Liu H,Han H,Xu B,Zhou Y,Li B,Zhang Y,Sun Z,Gong J,Li L,Wu W

doi

10.1080/00016489.2019.1571280

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

299-303

issue

3

eissn

0001-6489

issn

1651-2251

journal_volume

139

pub_type

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