Abstract:
BACKGROUND:pH monitoring can reflect the changes in H+ in the airway. OBJECTIVES:To explore the utility of pharyngeal pH monitoring in the diagnosis of laryngopharyngeal reflux disease (LPRD). MATERIAL AND METHODS:Clinical data from 956 suspected LPRD patients from February 2016 to March 2018 were analyzed retrospectively. RESULTS:One hundred forty-one patients had positive Ryan score. The positive rates of reflux symptom index (RSI), reflux finding score (RFS), RSI and RFS and RSI or RFS were 14.7%, 32.5%, 21.9%, 7.8% and 46.5%, respectively. The RFS in the positive Ryan score group was higher than that in the negative Ryan score group [(6 ± 3.5) vs. (4.8 ± 2.9)], while the RSI was not significantly different from that in the negative Ryan score group [(10.9 ± 8) vs. (11.3 ± 7.1)]. Regarding Ryan score as the gold standard in the diagnosis of LPRD, the sensitivity, specificity, positive and negative predictive value of identifying LPRD by RSI/RFS were 15.9%, 86.3%, 50.4% and 54%, respectively. CONCLUSIONS:Ryan score, RSI and RFS have poor correlation in detecting LPRD. Some patients may be missed with the Ryan score as a diagnostic criterion. SIGNIFICANCE:Pharyngeal pH monitoring is useful and more appropriate index is expected.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Wang G,Qu C,Wang L,Liu H,Han H,Xu B,Zhou Y,Li B,Zhang Y,Sun Z,Gong J,Li L,Wu Wdoi
10.1080/00016489.2019.1571280subject
Has Abstractpub_date
2019-03-01 00:00:00pages
299-303issue
3eissn
0001-6489issn
1651-2251journal_volume
139pub_type
杂志文章abstract:OBJECTIVE:To determine the role of cell proliferation neoplastic progression in the larynx and possibly derive criteria of clinical significance using automated quantitative image analysis. MATERIAL AND METHODS:In a retrospective study involving archival material, the occurrence and location, size, shape and staining ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/0001648021000028135
更新日期:2003-08-01 00:00:00
abstract::The DBA/2 strain of mice have genetically induced vestibular dysfunction that presents grossly at an early age as circling behavior and abnormal righting reflexes. The vestibular morphology of this strain has not previously been examined. DBA/2 mice of different ages that showed circling behavior were sacrificed and t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126075
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abstract::One hundred patients subjected to tonsillectomy because of recurrent acute tonsillitis or tonsillar hypertrophy were evaluated bacteriologically both with ordinary throat culturing and cultures from tonsillar cores. In 26% of the patients H. influenzae was isolated and in 20% beta-haemolytic group A streptococci. Grow...
journal_title:Acta oto-laryngologica
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doi:10.3109/00016489009107448
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVE:To investigate whether the extent of expression of hyaluronan (HA) and epidermal growth factor receptor (EGFR) in squamous cell carcinoma of the mobile tongue can predict the risk of cervical metastasis and survival. STUDY DESIGN:Retrospective histopathologic study. METHODS:Surgical specimens from 64 patien...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1292049
更新日期:2017-08-01 00:00:00
abstract::Based on the experimental results of thyroplasty, thyroplasty type I which aims at medical shifting the vocal cord was performed on 8 patients with dysphonia, 6 with vocal cord paralysis and 2 with vocal cord atrophy. The surgery was conducted on either in- or out-patient basis and local anesthesia was used. Usually, ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121353
更新日期:1975-11-01 00:00:00
abstract::A delayed conditioning paradigm was employed to condition the stapedius muscle. While many previous attempts have failed using loud sound as the unconditioned stimulus(UCS), this paper presents evidence of successful conditioning of this muscle when the unconditioned stimulus was a mild electrocutaneous stimulation of...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
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abstract::The maculae sacculi and utriculi of the chinchilla vestibular labyrinth have been studied by freeze-fracture method. In the replicas extensive zonulae occludentes have been found between sensory and supporting cells at the endolymphatic surface. Gap junctions are located between the supporting cells. Some intramembran...
journal_title:Acta oto-laryngologica
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doi:10.3109/00016487709128816
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abstract::The aim of this study was to evaluate the effects of argon laser irradiation of the semicircular canals using computed tomography (CT) images and to examine the basis for laser treatment for benign paroxysmal positional vertigo (BPPV). CT images of the posterior canal were evaluated postoperatively in a patient with i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.622292
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abstract:CONCLUSION:Gene transcription and protein expression of α-ENaC showed a divergent expression in association with the development of OME induced by barotrauma. OBJECTIVES:ENaC was identified to mediate the fluid absorption through epithelia of the middle ear. This study was designed to investigate the involvement of EN...
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pub_type: 杂志文章,多中心研究
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abstract::Taking advantage of a natural experimental situation, we compared, retrospectively, functional results after nasalization and ethmoidectomy for diffuse nasal polyposis. Nasalization was a radical ethmoidectomy systematically removing all the bony lamellae and mucosa within the labyrinth, with large antrostomy, sphenoi...
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journal_title:Acta oto-laryngologica
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doi:10.1080/000164800750000991
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abstract::Seventeen cases of postinflammatory acquired artresia of the external auditory canal in 14 women are described and analysed. Fourteen of these cases were solid atresias in which the auditory canal was more or less filled with fibrous tissue. Three patients had partial membranous atresia. The aetiology was external oti...
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abstract::The efferent cochlear system, composed of both ipsi- and contralateral bundles, runs along with the vestibular nerve and may serve as protection for the inner ear. Sectioning of the vestibular nerve could thus create an experimental model for further in-depth study of such a protective role. A personal surgical approa...
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2000-08-01 00:00:00
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