Abstract：
BACKGROUND:Traumatic tympanic membrane perforation (TTMP) is usually managed conservatively because most close spontaneously within a few months. Nevertheless, spontaneous closure of TTMP during long-term observation has not been well described in the literature. OBJECTIVES:The present study investigated factors associated with spontaneous closure of TTMP, and the characteristics of cases exhibiting spontaneous closure following long-term observation. MATERIALS AND METHODS:The medical records of 40 patients with TTMP who visited the authors' hospital were retrospectively reviewed. RESULTS:Spontaneous closure was observed in 27 (67.5%) patients. The healing period was <2 weeks in 6 cases, <4 weeks in 9, <3 months in 5, <6 months in 3, and ≥6 months in 4. All four cases in which spontaneous closure took ≥6 months exhibited a sign of spontaneous closure at 6 months following injury. Perforation in contact with the malleus was associated with a lower frequency of spontaneous closure. CONCLUSIONS AND SIGNIFICANCE:In TTMP, surgery should be considered in patients who exhibit perforation in contact with the malleus. However, it has also been suggested that long-term observation may be a viable treatment option when a sign of spontaneous closure is observed within 6 months following injury.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Tachibana T,Kariya S,Orita Y,Makino T,Haruna T,Matsuyama Y,Komatsubara Y,Naoi Y,Nakada M,Noda Y,Sato Y,Nishizaki Kdoi
10.1080/00016489.2019.1592225subject
Has Abstractpub_date
2019-06-01 00:00:00pages
487-491issue
6eissn
0001-6489issn
1651-2251journal_volume
139pub_type
杂志文章abstract：OBJECTIVES:This study was conducted to demonstrate the safety and efficacy of the Otologics Middle Ear Transducer (MET) Ossicular Stimulator and, in particular, to compare the audiologic benefits of this novel form of electromechanical stimulation with those of conventional acoustical amplification. MATERIAL AND METHO...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章,多中心研究
doi：10.1080/00016480410016298
更新日期：2004-05-01 00:00:00
abstract：:Five temporal bones and three surgical cochlear nerve specimens from patients who previously underwent labyrinthectomy were studied by light and electron microscopy. All cochleas had nearly total loss of sensory cells, extensive or total loss of both cochlear nerve fibers in the osseous spiral lamina, and spiral gangl...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488109138495
更新日期：1981-03-01 00:00:00
abstract：:Background: Frequency-specific hearing studies are important for predicting hearing results and the prognosis after stapes surgery, to prepare for the rehabilitation of frequency-specific hearing in patients with otosclerosis.Objectives: To evaluate outcomes of stapes surgery of Chinese otosclerosis patients with diff...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.1080/00016489.2020.1724331
更新日期：2020-05-01 00:00:00
abstract：:Background: In clinical experience patients who do not frequently check the cochlear implant (CI) maps have poor auditory performance and poor acceptance of map variations over time.Aims: The aim of the present study was to evaluate the effect of CI map optimization on both speech perception and subjective hearing in ...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.1080/00016489.2019.1700303
更新日期：2020-02-01 00:00:00
abstract：:On-line measurement of ME gas composition in normal middle ears of 5 anesthetized guinea pigs at an established steady state was performed by mass spectrometry. The mean values for the gas composition of the middle ear were found to be: PN2: 82.4%, PO2: 7.6% and PCO2: 10.0%. This composition is very different from tha...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016489309135824
更新日期：1993-05-01 00:00:00
abstract：:Background: Betahistine is used worldwide to treat patients with Menière's disease. However, despite it being used for decades, diverging opinions on the effect of betahistine on Menière's symptomatology still exist.Aims: The objective of this systematic review was to provide an overview and rate the certainty of the ...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.1080/00016489.2020.1777326
更新日期：2020-10-01 00:00:00
abstract：:Endoscopy is needed for reliable evaluation of the treatment of nasal polyposis. In this study, we compared the reproducibility of various score systems for staging nasal polyposis and the inter-individual variations between investigators. The mass of the polyps was assessed by five methods, three new techniques (numb...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.1080/000164800760370873
更新日期：2000-01-01 00:00:00
abstract：:Nerves displaying vasoactive intestinal peptide (VIP) immunoreactivity were detected in the upper respiratory tract of guinea pigs, rabbits and cats. VIP nerves were numerous in the cat, less numerous in the rabbit and rare in the guinea pig. In the nasal mucosa, fine varicose VIP nerves were found to surround nasal g...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016487809107524
更新日期：1978-11-01 00:00:00
abstract：:Interleukins 6 (IL-6) and 12 (IL-12), and the chemoattractant chemokine RANTES were studied in ethmoidal mucosa, using reverse transcriptase polymerase chain reaction. The 49 patients had chronic sinusitis or nasal/paranasal polyposis, and some also allergy. To the best of our knowledge, this is the first study that d...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016489609137897
更新日期：1996-07-01 00:00:00
abstract：:An influence of complete mechanical obstruction of the nasal passages was investigated in 6 apneic-free sons of fullblown sleep apnea patients and in 4 age-matched normal young adults without a familial history of sleep apnea. Nasal obstruction caused a significant increase in the number of sleep apneas in the sons of...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488409130972
更新日期：1984-01-01 00:00:00
abstract：:Patients with chronic otitis media (COM) were divided into two groups, one to be given Cephalexin (CEX) orally and the other to be given CEX ear drops locally. The counts of viable bacteria in otorrheal samples collected before and after CEX administration were determined. The incidence of decrease in the count of bac...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488109133264
更新日期：1981-09-01 00:00:00
abstract：:Nasal polyps is a chronic inflammatory disease of the upper airway characterized by structural abnormalities including stromal fibrosis. Fibroblasts are a rich source of cytokines and inflammatory mediators and are thought to play an important role in the development of fibrosis. In addition, there is considerable evi...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.1080/00016489950180478
更新日期：1999-01-01 00:00:00
abstract：CONCLUSIONS:The critical stage for cochlear gene regulation in the embryo is E49-E56. These data provide a valuable resource to help elucidate gene regulation in cochlear development and will benefit ear-related studies, especially those that focus on gene and stem cell therapies in hearing loss. OBJECTIVES:To investi...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.1080/00016489.2017.1341641
更新日期：2017-11-01 00:00:00
abstract：:In rabbits the nasal vestibule was surgically occluded on one side. The rabbits were observed for varying periods, maximum 90 days. The mucosa of the septum was removed from both sides, stained by the PAS-alcian blue whole-mount method, and the goblet cells were counted. The difference in goblet-cell density between t...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016487809124749
更新日期：1978-09-01 00:00:00
abstract：CONCLUSION:Vestibular disturbance is frequent, but mild even immediately after stapes surgery. Vestibular symptoms improved or disappeared quickly, and they did not correlate with nystagmus. Outpatient stapes surgery performed under local anaesthesia is a feasible approach. OBJECTIVE:Vestibular symptoms are common and...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016489.2013.782106
更新日期：2013-08-01 00:00:00
abstract：:The ultrastructural pattern of the acoustic nerve Schwannoma was studied on surgically excised tumours and on explants cultured in vitro. The typical neoplastic cell is elongated, spindle-shaped, coated with basement membrane and numerous protruding cellular processes. Cells demonstrating numerous microfilaments are a...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488509108909
更新日期：1985-03-01 00:00:00
abstract：:Reserpine (2 mg/kg and 10 mg/kg, i.p.), an adrenergic blocker, was administered to normal guinea pigs, and samples of serum, CSF, scala tympani perilymph, scala vestibuli perilymph and cochlear endolymph were collected. The concentrations of Na and K in these fluids were then assessed to observe electrolyte distributi...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488409107540
更新日期：1984-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the capability of indirect computed tomography and magnetic resonance lymphography (CT/MR-LG) with gadolinium-loaded, polyethylenimine-entrapped gold nanoprobes (Gd-Au PENPs) for assessing lingual sentinel lymph node (SLN) metastasis in a tongue VX2 carcinoma model. MATERIALS AND METHODS:Seventee...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.1080/00016489.2018.1441544
更新日期：2018-08-01 00:00:00
abstract：:Cochlear endolymph, scala tympani perilymph, and scala vestibuli perilymph were collected from fetal, neonatal, and mature guinea pigs. The concentrations of Na and K in these fluids were then assessed using a microflame photometer. The electrolyte composition in the endolymph was already characterized by a high conce...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488509182256
更新日期：1985-05-01 00:00:00
abstract：:The use of SEM as an adjunct to TEM and electrophysiological examination of the cochlea is now well established. It has provided a relatively simple method of assessing the effect of noise, ototoxic drugs, electrical stimulation, etc. on the surface features of the organ of corti. A controlled experiment was undertake...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488509126566
更新日期：1985-11-01 00:00:00
abstract：:The effect of adaptation of the ear on the SISI test was studied at 500 Hz and 2000 Hz in 43 patients with chronic otitis and in 20 patients with otosclerosis. The mean adaptation was slightly over 10 dB, except in the otosclerosis group at 2000 Hz, for which the value was nearly 20 dB after continuous stimulation at ...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016487509121302
更新日期：1975-07-01 00:00:00
abstract：:In a previous study, the authors described a technique for recording ipsilateral EABRs using the DIGISONIC MXM cochlear implant (Gallégo et al, Acta Otolaryngol (Stockh) 1996; 116: 228-33) and showed that the EABR input/output functions were very similar across electrodes. In the present study a test of electrode func...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016489709117761
更新日期：1997-03-01 00:00:00
abstract：CONCLUSION:Compared with normal-weight individuals, obese young adults exhibited a significantly higher taste threshold for salty taste. Smoking also affected taste functions in this population. OBJECTIVE:The aim of this study was to investigate the differences in taste detection thresholds between normal-weight and o...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016489.2014.975370
更新日期：2015-05-01 00:00:00
abstract：CONCLUSION:The data suggest that histamine up-regulates MUC2 gene regulation and mucin production in airway epithelial cells through histamine 1 receptor (H1R). Histamine appears to play an important role in the early phase of mucin regulation, which might be effectively blocked by an H1R antagonist. OBJECTIVE:Histami...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016489.2012.661075
更新日期：2012-06-01 00:00:00
abstract：CONCLUSIONS:The midfacial degloving approach is a favorable option for advanced sinonasal inverted papilloma with a fair recurrence rate, and can replace the lateral rhinotomy approach, which is considered too invasive for benign tumor due to its facial scar. OBJECTIVE:This study aimed to assess the treatment outcomes...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016480903311211
更新日期：2010-04-01 00:00:00
abstract：:Three hundred and fifty-four patients with squamous cell carcinoma of the oral cavity, oropharynx, supraglottic larynx, hypopharynx or maxillary sinus have been randomized for preoperative radiation therapy and surgery versus surgery and postoperative radiation therapy plus, in the case of patients with lesions of the...
journal_title：Acta oto-laryngologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.3109/00016488109138548
更新日期：1981-05-01 00:00:00
abstract：:Two hundred Malaysian patients representing 227 ears with previously untreated cholesteatoma disease were analysed retrospectively in terms of i) type of disease, i.e. primary acquired attic defect or posterior superior retraction pocket and secondary acquired type cholesteatoma; ii) positive history of previous middl...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016489109138380
更新日期：1991-01-01 00:00:00
abstract：:A retrospective study was carried out on repeated audio-vestibular examinations in 53 patients with unilateral Meniere's disease, between the vertiginous spells. Most patients showed no change in the caloric response reduction of the afflicted ear in the subsequent tests compared with the first one. These patients had...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488109133278
更新日期：1981-11-01 00:00:00
abstract：:The distribution of the Substance P (SP) immunoreactive nerve fibres in the canine larynx and laryngeal nerves was studied by PAP immunohistochemistry. Many individual SP immunoreactive nerve fibres with varicosities were observed within the epithelial layer and in the connective tissue below the epithelium of the lar...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.3109/00016488509108597
更新日期：1985-07-01 00:00:00
abstract：:We studied the influence of neck afferents on the perception of orientation. In Experiment 1, we investigated the effect of head tilt on the subjective vertical in both the visual and tactile modalities. The results showed that head tilt triggers an Aubert effect in the visual modality and a Müller effect in the tacti...
journal_title：Acta oto-laryngologica
pub_type： 杂志文章
doi：10.1080/000164800750000261
更新日期：2000-09-01 00:00:00
