The effect of initial treatment on hearing prognosis in idiopathic sudden sensorineural hearing loss: a nationwide survey in Japan.

Abstract:

OBJECTIVE:To investigate the hearing prognosis of idiopathic sudden sensorineural hearing loss (SSNHL) treated with different initial therapies. METHODS:Subjects consisted of patients diagnosed with idiopathic SSNHL within 7 days from onset and showing severe hearing loss (≥60 dB), who were registered in a Japanese multicenter database between April 2014 and March 2016. Subjects were divided into four groups according to initial therapy: (1) steroids, (2) steroids + Prostaglandins (PGs), (3) intratympanic steroids (ITS), and (4) no steroids. Hearing outcomes were compared among the groups. RESULTS:In total, 1305 patients were enrolled. The final hearing level and hearing gain of patients treated with steroids + PGs were significantly higher than those of patients treated with steroids alone or no steroids. The ratio of good prognosis (complete recovery or marked improvement) in patients treated with steroids + PGs was higher than that in patients treated with steroids alone or no steroids. There was no difference in the prognosis of patients treated with steroids alone or no steroids. CONCLUSION:A large number of patients with idiopathic SSNHL were registered in a multicenter database. PG use in combination with steroid administration was associated with a good hearing prognosis in patients with severe hearing loss.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Okada M,Hato N,Nishio SY,Kitoh R,Ogawa K,Kanzaki S,Sone M,Fukuda S,Hara A,Ikezono T,Ishikawa K,Iwasaki S,Kaga K,Kakehata S,Matsubara A,Matsunaga T,Murata T,Naito Y,Nakagawa T,Nishizaki K,Noguchi Y,Sano H,Sato

doi

10.1080/00016489.2017.1296970

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

S30-S33

issue

sup565

eissn

0001-6489

issn

1651-2251

journal_volume

137

pub_type

杂志文章,多中心研究
  • The development of medial geniculate body in man: changes in the cholinesterase (CHE) activity during fetal and perinatal life.

    abstract::In the present study cholinesterase histochemical (ChE) techniques have been used to demonstrate differentiation and maturation of the medial geniculate body (MGB) in the human fetuses (ranging between 10.5 to 28 weeks) and infants (premature and three postnatal months). In the youngest specimens examined (10.5 to 15 ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309139464

    authors: Krmpotić-Nemanić J,Kostović I,Nemanić D

    更新日期:1983-05-01 00:00:00

  • Critical bands following the selective destruction of cochlear inner and outer hair cells.

    abstract::Critical bandwidths and absolute intensity thresholds were measured in cats before and after kanamycin treatment which induced selective inner and outer hair cell losses. Hair cell losses were measured from cochleograms constructed from surface preparations of the organ of Corti. Results suggested that, for the test f...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487909137179

    authors: Nienhuys TG,Clark GM

    更新日期:1979-01-01 00:00:00

  • Surgical treatment of vertigo by utriculostomy: an experimental study in sheep.

    abstract::The objective of this study was to develop and test an endolabyrinthic microsurgical procedure for treatment of vertigo, the utriculostomy. This involves the application of local heat for obtaining a fistula in the membranous labyrinth, so as to establish communication between the endolymphatic and perilymphatic space...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489950180739

    authors: Lavinsky L,Goycoolea M,Gananca MM,Zwetsch Y

    更新日期:1999-01-01 00:00:00

  • Management of the neck in node-positive tonsillar cancer.

    abstract:CONCLUSION:Neck dissection (ND) may not be warranted for those patients with complete response in the neck. Human papillomavirus (HPV)-positive or -negative tumour does not affect this recommendation. OBJECTIVES:Treatment of tonsillar cancer varies considerably worldwide, although non-surgical treatment, e.g. radiothe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2014.920516

    authors: Marklund L,Lundberg B,Hammarstedt-Nordenvall L

    更新日期:2014-10-01 00:00:00

  • Evaluation of phenotype of mononuclear host cells isolated from primary tumour and peripheral blood of patients with laryngeal carcinoma.

    abstract::Mononuclear host cells isolated from primary laryngeal carcinoma were assessed by means of indirect immunofluorescence with a panel of monoclonal antibodies against various lymphocyte subsets and macrophages. Tumours of various staging groups were examined in parallel with cells isolated from patient and donor periphe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488809119459

    authors: Zeromski J,Pietrzak J,Szmeja Z,Jezewska E,Górny MK,Kruk-Zagajewska A

    更新日期:1988-01-01 00:00:00

  • Further studies of the membrane potential of the stria cells of the guinea pig in vitro.

    abstract::Negative membrane potentials from the stria vascularis of the guinea pig have been recorded in vivo. Stable negative membrane potentials from the stria cells have also been recorded for as long as 2 minutes in vitro. They varied from -20 mV to -49 mV, irrespective of whether the stria vascularis was immersed in Ring...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487909137159

    authors: Chou JT,Hellenbrecht D

    更新日期:1979-01-01 00:00:00

  • In vitro cholesteatoma growth and secretion of cytokines.

    abstract:CONCLUSION:Our results show a significant difference between skin and cholesteatoma biology in vitro. OBJECTIVES:Cholesteatoma disease is a process of destruction characterized by uncontrolled growth of squamous epithelial cells in the middle ear or temporal bone. The pathophysiology behind the cholesteatoma developme...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480903413657

    authors: Helgaland T,Engelen B,Olsnes C,Aarstad HJ,Vassbotn FS

    更新日期:2010-07-01 00:00:00

  • Contrast-enhanced MRI of the inner ear after intratympanic injection of meglumine gadopentetate or gadodiamide hydrate.

    abstract:CONCLUSION:The degree of contrast enhancement of the cochlea after intratympanic administration of meglumine gadopentetate (Gd-DTPA) or gadodiamide hydrate (Gd-DTPA-BMA) varies widely among patients with inner ear diseases. There was no morphological change in the stria vascularis after Gd-DTPA or Gd-DTPA-BMA was place...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2010.507781

    authors: Suzuki H,Teranishi M,Naganawa S,Nakata S,Sone M,Nakashima T

    更新日期:2011-02-01 00:00:00

  • The characteristics of monosyllable recognition in Mandarin-speaking patients with auditory neuropathy.

    abstract::Background: A set of Chinese Mandarin monosyllable test lists has been widely used in clinical diagnosis, while the performance of the Mandarin-speaking patients with auditory neuropathy (AN) in the monosyllable tests was still unknown.Objectives: To analyze the characteristics of monosyllable recognition in Mandarin-...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2020.1726459

    authors: Xu L,Chen W,Yuan S,Yang S,Ji F

    更新日期:2020-06-01 00:00:00

  • Psychosomatic aspects of Menière's disease.

    abstract::The author presents a study of the personality structure, youth development and the role of interhuman conflicts in the work situation and the family, in the causation and course of Menière's disease, the somatopsychic reactions of the patients to the illness, and the principles of a form of psychotherapy which was co...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309139423

    authors: Groen JJ

    更新日期:1983-05-01 00:00:00

  • Management of facial palsy after temporal bone fracture via the transmastoid approach.

    abstract:CONCLUSION:The outcomes of extended subtotal facial nerve decompression via the transmastoid approach were good for facial palsy after temporal bone fracture (TBF). Surgical decompression should be carried out as soon as possible within 8 weeks after trauma. OBJECTIVE:To present outcomes of facial palsy after TBF via ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2014.981287

    authors: Liu Y,Liu S,Li J,Chen X,Sun J,Li Y

    更新日期:2015-03-01 00:00:00

  • Embryogenesis of the inner ear. II. The late differentiation of the mammalian crista ampullaris in vivo and in vitro.

    abstract::The embryonic development of the crista ampullaris of the CBA/CBA mouse was followed both in organ culture of explanted inner ears of the 16th gestational day and in vivo from the 16th gestational day until the 21st day, an age corresponding to birth. Cytodifferentiation of the sensory epithelium of the crista ampulla...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309132868

    authors: Nordemar H

    更新日期:1983-07-01 00:00:00

  • Photochemically induced double lateral wall lesions in the guinea pig cochlea.

    abstract:OBJECTIVE:Multiple patches of atrophy have been reported in the stria vascularis (SV) in elderly persons with presbycusis The aim of this study was to investigate the correlation between sensorineural hearing loss and this strial condition. MATERIALS AND METHODS:We established a new animal model comprising two small l...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/0001648021000028131

    authors: Takeshita T,Iwasaki S,Nagura M,Watanabe T,Umemura K,Hoshino T

    更新日期:2003-04-01 00:00:00

  • The influence of an insecticide on the function of the eustachian tube.

    abstract::Organophosphorus compounds in the form of insecticides are in widespread use and have recently attracted considerable interest as environmentally toxic agents. As little is known about the effect of environmental toxins on the tubal function in the ear, we studied the middle ear pressure necessary to force the eustach...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489509139361

    authors: Bergler W,Juncker C,Petroianu G,Keilmann A,Hörmann K

    更新日期:1995-07-01 00:00:00

  • Meniere's disease and middle ear pressure: vestibular function after transtympanic tube placement.

    abstract:CONCLUSION:Selected patients with Meniere's disease (MD) show an improvement of disability from vertigo after transtympanic ventilation tube insertion, although an effect on vestibular function is not seen if ipsilateral middle ear pressure lower than -50 daPa is used as a selection criterion. OBJECTIVES:Transtympanic...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480902791678

    authors: Park JJ,Chen YS,Westhofen M

    更新日期:2009-12-01 00:00:00

  • Clinical outcomes of platinum-based chemotherapy plus cetuximab for recurrent or metastatic squamous cell carcinoma of the head and neck: comparison between platinum-sensitive and platinum-resistant patients.

    abstract:BACKGROUND:Combination therapy consisting of a platinum agent, 5-fluorouracil and cetuximab (EXTREME regimen) is recommended for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M-SCCHN). However, it is advisable to use platinum-free regimens as first-line therapy in patients resistant to platinu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,多中心研究

    doi:10.1080/00016489.2018.1551623

    authors: Sato H,Tsukahara K,Okamoto I,Katsube Y,Shimizu A,Kondo T,Hanyu K,Fushimi C,Okada T,Miura K

    更新日期:2019-02-01 00:00:00

  • Post-tonsillectomy haemorrhage: a retrospective comparison of abscess- and elective tonsillectomy.

    abstract:CONCLUSION:There is no increased risk of postoperative haemorrhage for abscess tonsillectomies in comparison to elective tonsillectomies. OBJECTIVE:There is still controversy as regards the optimal management of peritonsillar abscess. Opponents of tonsillectomy à chaud cite an increased postoperative bleeding risk. Mo...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480510012336

    authors: Lehnerdt G,Senska K,Jahnke K,Fischer M

    更新日期:2005-12-01 00:00:00

  • Complications of temperature-controlled radiofrequency volumetric tissue reduction for sleep-disordered breathing.

    abstract:OBJECTIVE:Temperature-controlled radiofrequency volumetric tissue reduction (RFVTR) is a minimally invasive technique used in the treatment of the tongue base, soft palate and turbinates. Complications seem to be rare, but the scope of previous studies was often limited by the small number of patients included. The aim...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480310001385

    authors: Stuck BA,Starzak K,Verse T,Hörmann K,Maurer JT

    更新日期:2003-05-01 00:00:00

  • The estimated incidence of symptomatic nasal polyps.

    abstract::The objective of the present study was to establish the estimated incidence of symptomatic nasal polyps within a defined geographic area. Over a 6-year period all polyp patients diagnosed for the first time (n = 252; 174 males, 78 females) were prospectively registered at the study clinic. An estimated background popu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480252814199

    authors: Larsen K,Tos M

    更新日期:2002-03-01 00:00:00

  • Bone marrow cells as an origin of immune-mediated hearing loss.

    abstract::The MRL/lpr mouse, which is homozygous for the recessive lpr genes and has a mutation in the Fas gene encoding a cell-surface receptor for apoptosis, exhibits severe lymphadenopathy and develops systemic lupus erythematosus (SLE)-like disease. It has recently been reported that this mouse also manifests sensorineural ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480310015344

    authors: Iwai H,Lee S,Baba S,Tomoda K,Inaba M,Ikehara S,Yamashita T

    更新日期:2004-01-01 00:00:00

  • Ciliogenesis in human vestibular epithelia. A scanning electron microscopic study.

    abstract::Ciliogenesis events in human vestibular epithelia develop as an asynchronous process between neighbouring cells, but it is a synchronous one within each sensory cell, presenting the following stages. Initially, the cilia buds appear as stubby cylinders well aligned on the cuticular plate of the presumptive sensory cel...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488509108931

    authors: Sánchez-Fernández JM,Rivera-Pomar JM

    更新日期:1985-03-01 00:00:00

  • Late nodal metastasis of T2 oral cancer can be reduced by a combination of preoperative ultrasonographic examination and frozen section biopsy during supraomohyoid neck dissection.

    abstract:CONCLUSION:The occult metastasis rate for T2 oral cancer can be reduced by ultrasonography (US). Also, the late metastasis rate is considered to be reduced by combining US with frozen section biopsy (FSB) during supraomohyoid neck dissection (SOHND). OBJECTIVES:Early oral cancer has been reported to show occult metast...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2011.598553

    authors: Lee K,Nishikawa S,Yoshimura K,Kawata R

    更新日期:2011-11-01 00:00:00

  • The role of alternative GJB2 transcription in screening for neonatal sensorineural deafness in Austria.

    abstract:CONCLUSION:Alterations within a novel putative Exon 1a within the gap junction beta 2 (GJB2) gene may play a role in the development of genetic hearing impairment in Austria. OBJECTIVES:Mutations in the GJB2 gene are the most common cause of hereditary sensorineural deafness. Genome-wide screening for alternative tran...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2016.1249946

    authors: Parzefall T,Lucas T,Koenighofer M,Ramsebner R,Frohne A,Czeiger S,Baumgartner WD,Schoefer C,Gstoettner W,Frei K

    更新日期:2017-04-01 00:00:00

  • Evidence of direct communication of bone marrow cells with the endolymphatic sac in experimental autoimmune labyrinthitis.

    abstract::In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135786

    authors: Yamanobe S,Harris JP,Keithley EM

    更新日期:1993-03-01 00:00:00

  • Immunological investigations in laryngeal cancer.

    abstract::The authors carried out immunological investigations in 96 patients with laryngeal cancer. The following tests were applied: DNCB, PPD, phyto-test and the lymphocyte count. The patients were divided into three groups: 1) cured, one year following treatment; 2) relapses; 3) died during the first year. The separate grou...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487909126438

    authors: Krajina Z,Kosoković F,Bolanca S

    更新日期:1979-03-01 00:00:00

  • Central projections from singular parts of the vestibular labyrinth in the guinea pig.

    abstract::Primary afferent projections from singular parts of the vestibular labyrinth were studied in the guinea pig. The posterior ampullary nerve, the common trunk of the anterior and lateral ampullary nerves, as well as fibers innervating the macula sacculi or the macula utriculi were traced with crystals of horseradish per...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489209137430

    authors: Gstoettner W,Burian M,Cartellieri M

    更新日期:1992-01-01 00:00:00

  • Concentrations of chemical mediators in nasal secretions of patients with hay fever during natural allergen exposure.

    abstract::By using the microsuction technique, quantitative determination of the chemical mediators in nasal secretions was performed in 40 patients with seasonal allergic rhinitis during the pollen season. The aim of this study was to investigate the actual concentrations of these important mediators in nasal secretions during...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489409126103

    authors: Wang D,Clement P,Smitz J,Derde MP

    更新日期:1994-09-01 00:00:00

  • Heredity and symptoms in acromegaly.

    abstract::The author has performed clinical and follow-up studies of 80 acromegalic patients treated by transanthro-sphenoidal removal of the pituitary adenoma. Heredity for acromegaly or gigantism was recorded in 3.8% of the patients and other hereditary factors in 13.8%. Head trauma, meningitis or encephalitis was recorded in...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487609120891

    authors: Kinnman JE

    更新日期:1976-09-01 00:00:00

  • Pulsatile tinnitus in perimenopausal period.

    abstract::Sigmoid sinus diverticulum-induced pulsatile tinnitus is a rare medical problem. Here we report a case where pulsatile tinnitus occurred in the perimenopause with evidence of sigmoid sinus diverticulum. The tinnitus disappeared with the restoration of hearing after surgery. While diagnosis is critical for the treatmen...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2011.567998

    authors: Hou ZQ,Han DY

    更新日期:2011-08-01 00:00:00

  • Objective measurements of auditory nerve recovery function in nucleus CI 24 implantees in relation to subjective preference of stimulation rate.

    abstract:OBJECTIVE:Setting the optimal rate of stimulation for individual cochlear implant recipients is critical to the successful functional outcome of cochlear implantation. In the absence of an objective methodology, cochlear implants are currently fitted by means of a time-consuming (and therefore expensive) trial-and-erro...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480310002168

    authors: Shpak T,Berlin M,Luntz M

    更新日期:2004-08-01 00:00:00