Clinical outcomes of platinum-based chemotherapy plus cetuximab for recurrent or metastatic squamous cell carcinoma of the head and neck: comparison between platinum-sensitive and platinum-resistant patients.

abstract：:Human papillomavirus (HPV) has a well-established association with benign and malignant cervical tumours as well as with laryngeal papillomas, while its association with laryngeal carcinomas is still controversial. We have examined 39 squamous cell carcinomas of the larynx for HPV using PCR with three consensus primer...

journal_title：Acta oto-laryngologica

authors： Lie ES,Karlsen F,Holm R

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...

journal_title：Acta oto-laryngologica

authors： Chelikh L,Teixeira M,Martin C,Sterkers O,Ferrary E,Couloigner V

更新日期：2003-01-01 00:00:00

abstract：:The nystagmus and motion perception of two astronauts were recorded during Earth-vertical axis rotation and during off-vertical axis rotation (OVAR) before and after 7 days of spaceflight. Postflight, the peak velocity and duration of per- and postrotatory nystagmus during velocity steps about the Earth-vertical axis ...

journal_title：Acta oto-laryngologica

authors： Clement G,Darlot C,Petropoulos A,Berthoz A

更新日期：1995-09-01 00:00:00

abstract：:[3H]Dihydrostreptomycin was given intramuscularly to young pigmented guinea pigs and rats. Whole-body autoradiography, combined with densitometric measurement of the blackening of the autoradiograms, and liquid scintillation counting were used to determine the levels of radioactivity in the inner ear in relation to bl...

journal_title：Acta oto-laryngologica

authors： Nilsson Tammela M,Tjälve H

更新日期：1986-03-01 00:00:00

abstract：CONCLUSION:Our results demonstrate for the first time a potentially enhanced basal secretion of monocyte chemoattractant protein-1 (MCP-1) and interleukin (IL)-17A-stimulated secretion of IL-6 from nasal polyp fibroblasts, enhanced basal secretion of IL-6 from eosinophilic nasal polyp fibroblasts, and a remarkable up-r...

journal_title：Acta oto-laryngologica

authors： Homma H,Kamiya K,Kusunoki T,Ikeda K

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:To identify the difference of surgical margin and recurrence status of early stage tongue carcinoma via wide excision in a single institution with and without free flap reconstruction. OBJECTIVE:Survey whether the reconstruction methods for early tongue cancer affects disease control, survival outcomes. ME...

journal_title：Acta oto-laryngologica

authors： Lu CC,Tsou YA,Hua CH,Tsai MH

更新日期：2018-10-01 00:00:00

abstract：:The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Tr...

journal_title：Acta oto-laryngologica

authors： Mohammed el R,Profant M

更新日期：2011-06-01 00:00:00

abstract：:The biocompatibility of commercially available polyimides was examined in relation to the sensory and neural structures of the cochlea. Thin films of four different polyimides were prepared as substrates for photolithographically produced scala tympani electrode arrays and implanted in 32 cat cochleae. Following at le...

journal_title：Acta oto-laryngologica

authors： Haggerty HS,Lusted HS

更新日期：1989-01-01 00:00:00

abstract：:The subjective visual horizontal (SVH) was measured by means of a small, rotatable, luminous line in darkness in the upright head and body position and at 10, 20 and 30 degrees of tilt to the right and left before, and repeatedly during a follow-up period of 1 year after intratympanic gentamicin instillations in 12 pa...

journal_title：Acta oto-laryngologica

authors： Tribukait A,Bergenius J,Brantberg K

更新日期：1998-07-01 00:00:00

abstract：:Upper airway symptoms are common, but there is little information available on clinical findings in relation to indoor air pollution. This pilot study was conducted to test whether increased levels of indoor air pollutants in schools may correlate to a swelling of the nasal mucosa. The assumption was made that the deg...

journal_title：Acta oto-laryngologica

authors： Wålinder R,Norbäck D,Wieslander G,Smedje G,Erwall C

更新日期：1997-09-01 00:00:00

abstract：CONCLUSION:We demonstrated an early increase in aquaporin 2 (AQP2) expression in a motor nerve (extratemporal facial nerve, FN) following acute peripheral compression (crush), concomitant to effective development of motor dysfunction (facial palsy). The early increase in AQP2 expression that occurred concomitantly with...

journal_title：Acta oto-laryngologica

authors： Neiva FC,Borin A,Lee KS,Dias MV,Rodrigues BR,Testa JR,Cruz OL,Covolan L

更新日期：2015-07-01 00:00:00

abstract：:Interleukins 6 (IL-6) and 12 (IL-12), and the chemoattractant chemokine RANTES were studied in ethmoidal mucosa, using reverse transcriptase polymerase chain reaction. The 49 patients had chronic sinusitis or nasal/paranasal polyposis, and some also allergy. To the best of our knowledge, this is the first study that d...

journal_title：Acta oto-laryngologica

authors： Davidsson A,Danielsen A,Viale G,Olofsson J,Dell'Orto P,Pellegrini C,Karlsson MG,Hellquist HB

更新日期：1996-07-01 00:00:00

abstract：CONCLUSIONS:There was a difference in average score of the sensory organization test (SOT) of the case group (elderly instability) compared to the control group (healthy subjects). Cases had worse scores on the limits of stability (LOS) than controls, but were only able to confirm statistically significant differences ...

journal_title：Acta oto-laryngologica

authors： Faraldo-García A,Santos-Pérez S,Rossi-Izquierdo M,Lirola-Delgado A,Vaamonde-Sánchez-Andrade I,Del-Río-Valeiras M,Soto-Varela A

更新日期：2016-11-01 00:00:00

abstract：CONCLUSION:A 20 mm hole made backwards from the midpoint of the asterion to the mastoid process is suitable for a retrosigmoid keyhole approach with the aid of an endoscope. The endoscope-assisted retrosigmoid keyhole approach can be considered an effective and safe method for removal of vestibular schwannoma. OBJECTI...

journal_title：Acta oto-laryngologica

authors： Sun JQ,Sun JW

更新日期：2013-11-01 00:00:00

abstract：:Formation of carotid artery pseudoaneurysm is uncommon after intensive treatment for head and neck cancer. We encountered a case of postoperative formation of pseudoaneurysm at the left carotid bifurcation in a diabetic man. The risk factors for carotid artery pseudoaneurysm in the patient included diabetes mellitus, ...

journal_title：Acta oto-laryngologica

authors： Iguchi H,Takayama M,Kusuki M,Nakamura A,Kanazawa A,Hachiya K,Yamane H

更新日期：2006-05-01 00:00:00

abstract：CONCLUSION:From aspect of fluid dynamics, expanding patients' nasopharyngeal coronal-sectional area to 48.3-54.7% of normal area will bring the airflow velocity back to normal in adenoidal hypertrophy children. It might provide a suggestion for adenoidectomy range selection and whether total resection is necessary. OB...

journal_title：Acta oto-laryngologica

authors： Hu C,Han D,Zhou B,Zhang L,Li Y,Zang H,Li L

更新日期：2017-01-01 00:00:00

abstract：CONCLUSION:This study showed that elective neck dissection (ND) resulted in reduced regional recurrences in a selected group of surgically treated patients with pT1-2 carcinomas but did not show any benefit for disease-specific survival (DSS). Furthermore, the importance of pN classification was also verified for this ...

journal_title：Acta oto-laryngologica

authors： Psychogios G,Mantsopoulos K,Koch M,Klintworth N,Kapsreiter M,Zenk J,Iro H

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To assess paranasal sinus material histopathologically for the presence of fungus. MATERIAL AND METHODS:Paraffin-embedded archival biopsy samples of patients who underwent endonasal sinus surgery between 1992 and 2002 were retrospectively assessed for the presence of fungi. Hematoxylin-eosin-stained sections...

journal_title：Acta oto-laryngologica

authors： Erkiliç S,Aydin A,Bayazit YA,Güldür E,Deniz H,Bayazit N,Ozer E

更新日期：2003-04-01 00:00:00

abstract：:By using the microsuction technique, quantitative determination of the chemical mediators in nasal secretions was performed in 40 patients with seasonal allergic rhinitis during the pollen season. The aim of this study was to investigate the actual concentrations of these important mediators in nasal secretions during...

journal_title：Acta oto-laryngologica

authors： Wang D,Clement P,Smitz J,Derde MP

更新日期：1994-09-01 00:00:00

abstract：:The waltzing guinea pig exhibits genetically induced inner ear disease which develops into deafness and vestibular disorder. The type I hair cell in vestibular end organs shows specific pathology, featuring protrusion of the hair cell apex, sensory hair fusion and an intracellular actin filament rod. With the freeze-f...

journal_title：Acta oto-laryngologica

authors： Sobin A,Flock A,Bagger-Sjöbäck D

更新日期：1983-09-01 00:00:00

abstract：CONCLUSION:This study demonstrated that treatment with montelukast in combination with levocetirizine may have a beneficial effect on clinical improvement of middle ear fluid in children with otitis media with effusion (OME). OBJECTIVE:To evaluate the effect of the combination of montelukast and levocetirizine on shor...

journal_title：Acta oto-laryngologica

authors： Ertugay CK,Cingi C,Yaz A,San T,Ulusoy S,Erdogmus N,Ertugay OC

更新日期：2013-12-01 00:00:00

abstract：CONCLUSION:Bilateral electric acoustic stimulation (EAS) effectively improved speech perception in noise and sound localization in patients with high-frequency hearing loss. OBJECTIVE:To evaluate bilateral EAS efficacy of sound localization detection and speech perception in noise in two cases of high-frequency hearin...

journal_title：Acta oto-laryngologica

authors： Moteki H,Kitoh R,Tsukada K,Iwasaki S,Nishio SY,Usami S

更新日期：2015-02-01 00:00:00

abstract：CONCLUSION:Photodynamic therapy (PDT) is a viable and safe option for early laryngeal cancer that would be less suitably treated with radiation or trans-oral laser surgery (TLS). The cure rates with PDT appear to be comparable to those of conventional therapy, and the voice outcomes are also comparable. In the case of ...

journal_title：Acta oto-laryngologica

authors： von Beckerath MP,Reizenstein JA,Berner AL,Nordqvist KW,Landström FJ,Löfgren AL,Möller CG

更新日期：2014-08-01 00:00:00

abstract：CONCLUSIONS:We conclude that: (1) among several cues examined, the monaural cue of direct-to-reverberant (D/R) ratio in the ipsilateral ear provides the most information about sound-source distance; (2) interaural level difference (ILD) provides less information about sound-source distance; and (3) a comprehensive theo...

journal_title：Acta oto-laryngologica

authors： Kim DO,Moiseff A,Turner JB,Gull J

更新日期：2008-04-01 00:00:00

abstract：:In order to study the connection between occupation and sinonasal cancer we have reviewed the files and histological sections of 70 patients (24 females and 46 males) treated at the Department of Oto-rhino-laryngology, National Hospital of Norway. Detailed information concerning previous occupations was obtained by te...

journal_title：Acta oto-laryngologica

authors： Voss R,Stenersen T,Roald Oppedal B,Boysen M

更新日期：1985-01-01 00:00:00

abstract：CONCLUSIONS:The underlying pathophysiological mechanisms of the posterior nasal nerve (PNN) resection involved the suppression of the secretogogue motor and the inhibition of neurogenic inflammation induced by parasympathetic and sensory denervation. OBJECTIVE:The study was designed to clarify the underlying mechanism...

journal_title：Acta oto-laryngologica

authors： Ikeda K,Yokoi H,Saito T,Kawano K,Yao T,Furukawa M

更新日期：2008-01-01 00:00:00

abstract：:The postnatal development of lower stations in the auditory pathway was studied in the guinea pig by recording auditory brainstem potentials. At birth, the brainstem responses of young guinea pigs already have thresholds corresponding to those of adult animals. However, the latencies of the individual potentials are s...

journal_title：Acta oto-laryngologica

authors： Dum N

更新日期：1984-01-01 00:00:00

abstract：:Taking advantage of a natural experimental situation, we compared, retrospectively, functional results after nasalization and ethmoidectomy for diffuse nasal polyposis. Nasalization was a radical ethmoidectomy systematically removing all the bony lamellae and mucosa within the labyrinth, with large antrostomy, sphenoi...

journal_title：Acta oto-laryngologica

authors： Jankowski R,Pigret D,Decroocq F

更新日期：1997-07-01 00:00:00

abstract：:In a study on the effects of a frequency-dependent automatic gain control in hearing-aids, two experiments were carried out with hearing-impaired listeners. In the first experiment, the effect of varying the amplitude-frequency response on the speech-reception threshold (SRT) of sentences presented in noise was studie...

journal_title：Acta oto-laryngologica

authors： Van Dijkhuizen JN,Festen JM,Plomp R

更新日期：1990-01-01 00:00:00

abstract：:Between 1992 and 1996 14 patients with a squamous cell carcinoma of the laryngohypopharynx underwent tumour resection and primary reconstruction with the free volar forearm flap. Tumour resection was performed by a head and neck surgeon and reconstruction by a plastic surgeon. Preoperative radiotherapy was given to 13...

journal_title：Acta oto-laryngologica

authors： Stark B,Nathanson A

更新日期：1998-06-01 00:00:00