Expression of aquaporin 2 following facial nerve crush in rats.


CONCLUSION:We demonstrated an early increase in aquaporin 2 (AQP2) expression in a motor nerve (extratemporal facial nerve, FN) following acute peripheral compression (crush), concomitant to effective development of motor dysfunction (facial palsy). The early increase in AQP2 expression that occurred concomitantly with the appearance of a deficit in a peripheral motor nerve suggests that this protein is involved in the physiological events associated with post-injury edema, similar to the already demonstrated behavior of AQP4 in the central nervous system (CNS). OBJECTIVE:The aim of this study was to assess the expression of AQP2 in the FN of rats up to 7 days after crush. METHODS:The extratemporal trunk of the right FN of rats was subjected to mechanical crush, and the expression of AQP2 in the affected (right) and non-affected (left) FN was measured by means of western blotting at days 1, 3, and 7 after injury. Behavioral analysis of the development of facial palsy was also performed over the same time period. RESULTS:Increased expression of AQP2 was shown in the affected FN compared with its corresponding control at day 1 after compression, simultaneously with the appearance of facial palsy.


Acta Otolaryngol


Acta oto-laryngologica


Neiva FC,Borin A,Lee KS,Dias MV,Rodrigues BR,Testa JR,Cruz OL,Covolan L




Has Abstract


2015-07-01 00:00:00












  • Epiglottitis and necrotizing fasciitis: a life-threatening complication of infectious mononucleosis.

    abstract::Life-threatening cervical complications associated with infectious mononucleosis are rare. The combination of acute epiglottitis and subsequent necrotizing fasciitis of the head and neck in a patient with infectious mononucleosis has not been reported to date.A 47-year-old female with infectious mononucleosis and epig...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Caballero M,Sabater F,Traserra J,Alòs L,Bernal-Sprekelsen M

    更新日期:2005-10-01 00:00:00

  • Free flap reconstruction for early stage tongue squamous cell carcinoma: surgical margin and recurrence.

    abstract:BACKGROUND:To identify the difference of surgical margin and recurrence status of early stage tongue carcinoma via wide excision in a single institution with and without free flap reconstruction. OBJECTIVE:Survey whether the reconstruction methods for early tongue cancer affects disease control, survival outcomes. ME...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Lu CC,Tsou YA,Hua CH,Tsai MH

    更新日期:2018-10-01 00:00:00

  • Damaged utricular function clarified by oVEMP in patients with benign paroxysmal positional vertigo.

    abstract:CONCLUSION:Utricular dysfunction in patients with posterior canal benign paroxysmal positional vertigo (pBPPV) was supported by findings for ocular vestibular evoked myogenic potential (oVEMP). OBJECTIVE:To evaluate the utricular and saccular function in patients with pBPPV. METHODS:This study focused on 12 patients ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Nakahara H,Yoshimura E,Tsuda Y,Murofushi T

    更新日期:2013-02-01 00:00:00

  • Morphology of tracheal scar after resection with CO2-laser and high-frequency cutting loop. A study in normal pigs.

    abstract::In 6 pigs a bronchoscopical resection of the tracheal mucosa was performed using CO2-laser on one side, and an electric high-frequency cutting loop (ECL) on the other. The pigs were sacrificed 3 months later. On macroscopic examination the tracheal mucosa appeared almost normal on the laser-resected side, while severe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Vorre P,Illum P,Oster S,Reske-Nielsen E,Larsen KB

    更新日期:1989-03-01 00:00:00

  • Vestibulo-ocular reflex (VOR) in guinea pigs. Impairment induced by aminoglycoside antibiotics.

    abstract::The vestibulo-ocular reflexes (VORs) were studied in guinea pigs receiving daily administration of aminoglycoside antibiotics. The vestibular epithelia were also examined by scanning electron microscope technique (SEM). The treatment with aminoglycosides led to varying degrees of VORs according to (i) the type of amin...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Pettorossi VE,Bamonte F,Errico P,Ongini E,Draicchio F,Sabetta F

    更新日期:1986-05-01 00:00:00

  • Tick-borne borreliosis and facial palsy.

    abstract::During a one-year period, 82 consecutive patients seeking medical attention for facial palsy primarily of unknown etiology were examined for underlying Ixodes ricinus-borne borreliosis. Evidence of the infection was found in 16 (20%) of the patients, most of whom had cerebrospinal fluid findings indicating meningeal i...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Olsson I,Engervall K,Asbrink E,Carlsson-Nordlander B,Hovmark A

    更新日期:1988-01-01 00:00:00

  • Otoneurological findings in psycho-organic syndrome caused by industrial solvent exposure.

    abstract::Nine subjects with long-term (8-30 years) occupational exposure to industrial solvents and a confirmed diagnosis of psycho-organic syndrome (POS) have been studied with audiological and otoneurological test batteries. The results were compared to a matched control group of nine industrial workers not exposed to solven...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Möller C,Odkvist LM,Thell J,Larsby B,Hydén D,Bergholtz LM,Tham R

    更新日期:1989-01-01 00:00:00

  • Frequency-specific hearing results after stapes surgery for Chinese population otosclerosis with different degrees of hearing loss.

    abstract::Background: Frequency-specific hearing studies are important for predicting hearing results and the prognosis after stapes surgery, to prepare for the rehabilitation of frequency-specific hearing in patients with otosclerosis.Objectives: To evaluate outcomes of stapes surgery of Chinese otosclerosis patients with diff...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Zhang K,Fang Y,Wang B,Cheng X,Chen B,Shu Y

    更新日期:2020-05-01 00:00:00

  • Hearing impairment associated with spinal anesthesia.

    abstract:OBJECTIVES:Hearing loss after spinal anesthesia has been reported to be related to the transmission of a reduced subarachnoid pressure to the inner ear via the cochlear aqueduct due to loss of spinal fluid. However, there are also some controversies related to this phenomenon, which require systematic investigation. M...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Cosar A,Yetiser S,Sizlan A,Yanarates O,Yildirim A

    更新日期:2004-12-01 00:00:00

  • Occurrence of tracheal carcinoma in Finland.

    abstract::During the period 1967-1985, 95 primary tracheal carcinomas occurred in Finland. The mean annual incidence rate was one per one million inhabitants, the male:female ratio being 7:3. There was a significant increase of the disease by increasing age with the exception of 70-79 years. The most common location was the low...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Manninen MP,Antila PJ,Pukander JS,Karma PH

    更新日期:1991-01-01 00:00:00

  • The inner laryngeal lymphatics. A lymphangioscopical and electron microscopical study.

    abstract::Lymphangioscopical and ultrastructural studies of the larynx reveal a lymphatic capillary and a collecting vessel system. Collecting vessels show luminal valves and elastic structural components within the wall. Lymphangioscopy reveals that a strict compartmentation of different laryngeal areas is unjustifiable with t...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Beck C,Mann W

    更新日期:1980-03-01 00:00:00

  • Elemental composition of individual cells and tissues in the cochlea.

    abstract::Localization of elements at the cellular and sub-cellular levels was performed with the energy dispersive X-ray microanalysis technique, using shock-frozen, freeze-dried and araldite-embedded mouse (CBA/CBA) cochleae sectioned dry. Anatomical identification occurred in the STEM (scanning transmission electron microsco...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Anniko M,Lim D,Wróblewski R

    更新日期:1984-11-01 00:00:00

  • Vestibular neurectomy in the guinea-pig: a retrosigmoid approach.

    abstract::The efferent cochlear system, composed of both ipsi- and contralateral bundles, runs along with the vestibular nerve and may serve as protection for the inner ear. Sectioning of the vestibular nerve could thus create an experimental model for further in-depth study of such a protective role. A personal surgical approa...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Barbara M,Attanasio G,Piccoli F,Filipo R

    更新日期:1999-03-01 00:00:00

  • Sleep-related deglutition in patients with OSAHS under CPAP therapy.

    abstract:CONCLUSION:Continuous positive airway pressure (CPAP) therapy improved not only apnea-hypopnea during sleep and sleep structure but also sleep-related deglutition, especially respiratory phase patterns associated with deglutition. OBJECTIVES:Sleep-related deglutition and related respiratory phase patterns in patients ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Sato K,Umeno H,Chitose S,Nakashima T

    更新日期:2011-02-01 00:00:00

  • Endoscopic surgery for congenital basal meningoencephaloceles in children.

    abstract::Conclusions Endoscopic surgery is safe and effective for children with congenital basal meningoencephaloceles (CBMs); it provides an acceptable operative outcome with a short recovery time and fewer complications and may be considered as a primary approach. Objectives To explore the safety and effectiveness of using t...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Wu X,Zhang J,Zhang H,Xie Z,Fan R,Liu Y,Wu B,Sun H,Jiang W

    更新日期:2016-06-01 00:00:00

  • Inner ear injury caused by air intrusion to the scala vestibuli of the cochlea.

    abstract::In a previous communication, we demonstrated that the introduction of air into the scala tympani of the cochlea causes a decrease of cochlear potentials; however, the change in endocochlear dc potential (EP) was mild and the decreased cochlear microphonics (CM) and compound action potentials (CAP) were, at least parti...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Kobayashi T,Sakurada T,Ohyama K,Takasaka M

    更新日期:1993-11-01 00:00:00

  • Supernumerary outer hair cells arise external to the last row of sensory cells in the organ of corti.

    abstract::During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain obscure. When late embryonic or early postnatal rat organs of Corti we...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Lefebvr PP,Malgrange B,Thiry M,Breuskin I,Van De Water TR,Moonen G

    更新日期:2001-01-01 00:00:00

  • Computerized analysis of the caloric response.

    abstract::Caloric responses from 50 consecutive patients, referred routinely for investigation of hearing and/or balance problems, were evaluated by computer and manual methods of analysis. Using measures of nystagmic slow-phase velocity, there was found to be a high degree of correlation between the two methods. Of the 50 pati...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: O'Neill G,Owen WA

    更新日期:1987-11-01 00:00:00

  • An external neck brace to support the peristomal fixation of an automatic stoma valve (ASV): 3D stereophotogrammetrical assessment.

    abstract:CONCLUSION:The external neck brace (ENB) is a new concept in the improvement of peristomal fixation of an automatic stoma valve (ASV), which was evaluated with a new imaging method. The addition of the ENB to the Flexiderm (FLD) and Xtrabase (XB) adhesives significantly reduced absolute mean differences between the spe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Dirven R,Kooijman PG,Maal TJ,Hilgers FJ,Bergé SJ,Marres HA

    更新日期:2010-07-01 00:00:00

  • Ultrastructural changes of the basement membrane zone in benign lesions of the vocal folds.

    abstract::The basement membrane zone (BMZ) of the epithelium of the vocal folds was investigated electron microscopically in 10 patients suffering from various benign lesions and in 3 controls. Various defects were observed: a thickening by deposition of electron dense material, a loss of normal architecture, and a near absence...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Dikkers FG,Hulstaert CE,Oosterbaan JA,Cervera-Paz FJ

    更新日期:1993-01-01 00:00:00

  • Value of pulse oximetry watch for diagnosing pediatric obstructive sleep apnea/hypopnea syndrome.

    abstract:OBJECTIVE:To evaluate the clinical value of pulse oximetry watch (POW) for diagnosing pediatric Obstructive sleep apnea/hypopnea syndrome (OSAHS). METHODS:We selected 32 children (boys: 25, 4-16 years old) who came to the hospital for diagnosing OSAHS from July to October 2016. Polysomnography (PSG) and POW were used ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Ma JR,Huang JJ,Chen Q,Wu HT,Xiao KL,Zhang YT

    更新日期:2018-02-01 00:00:00

  • Otologics Middle Ear Transducer Ossicular Stimulator: performance results with varying degrees of sensorineural hearing loss.

    abstract:OBJECTIVES:This study was conducted to demonstrate the safety and efficacy of the Otologics Middle Ear Transducer (MET) Ossicular Stimulator and, in particular, to compare the audiologic benefits of this novel form of electromechanical stimulation with those of conventional acoustical amplification. MATERIAL AND METHO...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,多中心研究


    authors: Jenkins HA,Niparko JK,Slattery WH,Neely JG,Fredrickson JM

    更新日期:2004-05-01 00:00:00

  • Early timing of low-dose dexamethasone decreases inflammation in a murine model of eosinophilic airway disease.

    abstract:CONCLUSION:A very low dose of dexamethasone (DEX) was as equally as sufficient as a pharmacological dose to decrease eosinophil inflammation in airways and bone marrow. The timing of DEX treatment in relation to allergen challenge was strongly decisive for the outcome of the inflammatory response. OBJECTIVES:We aimed ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Georén SK,Tcacencu I,Wikström AC,Stierna P

    更新日期:2009-02-01 00:00:00

  • Late results in tympanoplasty. Staging the operation.

    abstract::Based on the late results of tympanoplasty on 300 ears and of one-stage mastoidectomy and tympanoplasty on 269 discharging ears, the problems involved in staging tympanoplasty are discussed. The results of one-stage operations were found to be satisfactory 2-10 years after operation. The frequency of recurrent cholest...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Tos M

    更新日期:1976-09-01 00:00:00

  • Experimental cholesteatoma. Epidermal ingrowth through tympanic membrane following middle ear application of propylene glycol.

    abstract::This study was designed to investigate morphological changes in the tympanic membrane (TM) associated with cholesteatoma formation in experimental animals following application of propylene glycol to the middle ear. A 50% solution of propylene glycol was applied bilaterally to the middle ear cavities of 30 young-adult...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Masaki M,Wright CG,Lee DH,Meyerhoff WL

    更新日期:1989-07-01 00:00:00

  • Can chronic nasal obstruction cause dysfunction of the paratubal muscles and otitis media? An experimental study in developing Wistar rats.

    abstract:OBJECTIVE:To quantitatively analyze modifications of the paratubal muscles in developing Wistar rats following nasal obstruction. MATERIAL AND METHODS:Twenty-four Wistar rats were used. Twelve were examined at 6, 8 and 12 weeks after birth and were considered normal controls. The nostrils of the remaining 12 rats were...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Scarano E,Fetoni AR,Picciotti P,Cadoni G,Galli J,Paludetti G

    更新日期:2003-01-01 00:00:00

  • High variability of perilymphatic entry of neutral molecules through the round window.

    abstract:OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Chelikh L,Teixeira M,Martin C,Sterkers O,Ferrary E,Couloigner V

    更新日期:2003-01-01 00:00:00

  • Analysis of the performance of post-lingually deafened patients with Nurotron(®) Venus™ cochlear implants.

    abstract:OBJECTIVE:The aim of this study was to analyze the safety and effectiveness of a new cochlear implant (CI) system developed in China, the Nurotron Venus device. MATERIAL AND METHODS:Fifteen post-lingually deafened patients received Nurotron Venus CIs in our hospital. The safety and effectiveness of the devices were ev...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Li J,Ji F,Chen W,Zhao H,Han D,Yang S

    更新日期:2014-06-01 00:00:00

  • Effects of topical nasal decongestants on histology of nasal respiratory mucosa in rabbits.

    abstract::The aim of this study was to evaluate histologic changes after long-term administration of the topical nasal decongestants phenylephrine and oxymetazoline. Ninety healthy rabbits were divided into 3 groups for topical administration for 1 week, 2 weeks, and 4 weeks. Each group was subdivided into 3 subgroups by topica...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Suh SH,Chon KM,Min YG,Jeong CH,Hong SH

    更新日期:1995-09-01 00:00:00

  • Pulsatile tinnitus in perimenopausal period.

    abstract::Sigmoid sinus diverticulum-induced pulsatile tinnitus is a rare medical problem. Here we report a case where pulsatile tinnitus occurred in the perimenopause with evidence of sigmoid sinus diverticulum. The tinnitus disappeared with the restoration of hearing after surgery. While diagnosis is critical for the treatmen...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Hou ZQ,Han DY

    更新日期:2011-08-01 00:00:00