Abstract:
CONCLUSIONS:The underlying pathophysiological mechanisms of the posterior nasal nerve (PNN) resection involved the suppression of the secretogogue motor and the inhibition of neurogenic inflammation induced by parasympathetic and sensory denervation. OBJECTIVE:The study was designed to clarify the underlying mechanisms of the resection of the PNN. PATIENTS AND METHODS:Ten patients with allergic rhinitis and non-allergic chronic rhinitis were enrolled in the study. Clinical symptoms were evaluated before and after administration of oxitropium bromide aerosol, and after the PNN resection. Biopsy specimens from the inferior turbinate mucosa obtained from five patients before and after resection of the PNN were examined. RESULTS:The application of oxitropium bromide resulted in a significant reduction of both watery rhinorrhea and nasal obstruction, but not sneezing or postnasal drip. Resection of the PNN also significantly improved both rhinorrhea and nasal obstruction. Morphometric analysis of the density of the nasal gland showed a significant reduction, whereas no significant change was recognized in the density of the vessels. A significant reduction in the number of infiltrating neutrophils, eosinophils, and lymphocytes was recognized.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Ikeda K,Yokoi H,Saito T,Kawano K,Yao T,Furukawa Mdoi
10.1080/00016480801935525subject
Has Abstractpub_date
2008-01-01 00:00:00pages
1337-41issue
12eissn
0001-6489issn
1651-2251pii
792858665journal_volume
128pub_type
杂志文章abstract::An X-ray energy dispersive analysis was performed on the mature serial sectioned freeze-dried mammalian labyrinth (CBA/CBA mouse). The elemental distribution in the endolymphatic and perilymphatic spaces revealed similar results as have been reported in the literature when withdrawing fluid for microanalysis. The cupu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009131744
更新日期:1980-11-01 00:00:00
abstract::An influence of complete mechanical obstruction of the nasal passages was investigated in 6 apneic-free sons of fullblown sleep apnea patients and in 4 age-matched normal young adults without a familial history of sleep apnea. Nasal obstruction caused a significant increase in the number of sleep apneas in the sons of...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409130972
更新日期:1984-01-01 00:00:00
abstract::One hundred and fifty-five patients with complaints indicating acute sinusitis were examined and their symptoms and signs registered. The final diagnosis--maxillary sinus empyema versus not empyema--was established by means of antral aspiration. A computer-based analysis of clinical data demonstrated the significance ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809097017
更新日期:1988-03-01 00:00:00
abstract::A homozygous mutant rat at the white spotting (Ws) locus showing a deficiency of melanocytes has recently been found (4, 5). The function and morphology of the inner ear of the Ws/Ws rat were examined by auditory brainstem response (ABR), endocochlear DC potential (EP), and electron microscopy. The mean ABR threshold ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126038
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to demonstrate the long-term effectiveness of Expansion Sphincter Pharyngoplasty (ESP) as a standalone surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients through a prospective multi-center study. MATERIAL AND METHODS:A prospective non-com...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2018.1533992
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Endolymphatic sac decompression has shown limited success for the treatment of Ménière's disease (MD). We have published a novel technique with very promising results for the treatment of refractory MD: the Endolymphatic Duct Blockage (EDB) with two titanium clips. One of the challenges of this technique was...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1481524
更新日期:2018-10-01 00:00:00
abstract:CONCLUSION:Nasal obstruction, rhinorrhea, and the amount of rhinorrhea that confidently reflect the parasympathetic stimulation can be used to more precisely predict nonspecific nasal hyper-reactivity (NHR). OBJECTIVE:We aimed to identify factors that confidently reflected the presence and the degree of NHR, measured ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.681798
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To develop a large animal model for studies of laryngeal abductor reinnervation. MATERIAL AND METHODS:Six minipigs underwent unilateral anastomosis of the phrenic nerve-abductor branch of the recurrent laryngeal nerve (RLN). Polyhydroxybutyrate (PHB) conduits were used for repair. At each of 30, 60 and 120 d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410022507
更新日期:2004-09-01 00:00:00
abstract::Multimodality therapy of advanced malignant tumours of the head and neck includes surgery, radiotherapy and chemotherapy. However, the cure rate for these tumours is low and guidelines for the selection and timing of therapy are needed. For such guidelines, tumour cell kinetic parameter studies, e.g. cell proliferatio...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309130933
更新日期:1983-01-01 00:00:00
abstract::Background: Atoh1, also named Math1, is essential for the development of inner ear hair cells. Many studies have confirmed that the absence of Atoh1 resulted in a total loss of inner ear hair cells, which indicates that Atoh1 plays very similar roles in the development of hair cells in the cochlea and vestibule. Objec...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1497855
更新日期:2018-11-01 00:00:00
abstract:CONCLUSION:Cochlear implant (CI) recipients' performance of lexical tone identification and consonant recognition can be enhanced by providing greater spectral details. OBJECTIVE:To evaluate the effects of increasing the number of total spectral channels on the lexical tone identification and consonant recognition by ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802032793
更新日期:2009-06-01 00:00:00
abstract:CONCLUSION:Utricular dysfunction in patients with posterior canal benign paroxysmal positional vertigo (pBPPV) was supported by findings for ocular vestibular evoked myogenic potential (oVEMP). OBJECTIVE:To evaluate the utricular and saccular function in patients with pBPPV. METHODS:This study focused on 12 patients ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.720030
更新日期:2013-02-01 00:00:00
abstract::Substance P has been proved an important neurotransmitter and neuromodulator, serving not only as an excitatory transmitter of the first afferent synapse of pain pathways but as a valuable neuromodulator in the primary cortical areas of sensosensorial integration. In the human acoustic cortex, substance P has been fou...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127525
更新日期:1989-05-01 00:00:00
abstract::We studied the pathological changes in the temporal bone and brainstem, with particular attention to the autolysis of red blood cells in and around the blood vessels, in six cases of brainstem death determined by auditory brainstem responses (ABRs). Our findings showed that the cochlea, the visceral organs and the spi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139287
更新日期:1995-03-01 00:00:00
abstract::IL2Rs, in the presence of IL2, mediate activation and proliferation of human normal lymphocytes and modulate functional changes of some human leukocytic malignancies. IL2Rs have been demonstrated also on human neoplastic and fetal non-hematologic cells in vitro, although their functional role has not been described. W...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1992.11665436
更新日期:1992-01-01 00:00:00
abstract::Beta 2-microglobulin (beta 2m) is a small polypeptide, related to the immunoglobulins and present on nucleated cells as part of the strong transplantation antigens. Elevated plasma levels have been recorded in patients with various malignant diseases. Human beta 2m has also been detected immunohistochemically in carci...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107571
更新日期:1984-09-01 00:00:00
abstract:CONCLUSION:Results from a database for sudden sensorineural hearing loss (SSNHL) demonstrate no correlation between laboratory findings, treatment, and outcome in 400 patients. The patients with pathological test results were not treated differently from those with normal test results. The value of laboratory findings ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480903161541
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Oropharyngeal squamous cell carcinoma (OPSCC) positive for human papillomavirus (HPV) increases wolrd wide. AIMS/OBJECTIVES:The objective for this study has been to evaluate tumor phenotypes and tumor host responses with respect to five-year disease-specific survival (DSS) in HPV(+) and HPV(-) patients. MA...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1497809
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVES:Hearing loss after spinal anesthesia has been reported to be related to the transmission of a reduced subarachnoid pressure to the inner ear via the cochlear aqueduct due to loss of spinal fluid. However, there are also some controversies related to this phenomenon, which require systematic investigation. M...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017143
更新日期:2004-12-01 00:00:00
abstract::Mucormycosis is a rare acute fatal fungal infection. It is typically observed in diabetic or immunocompromised patients but not in systemically healthy individuals. Here, we describe an unusual mucormycosis case in an immunocompetent patient who had clinical signs of a maxillary sinusitis and associated osteomyelitis ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500534439
更新日期:2006-09-01 00:00:00
abstract::Seven to eight years after a disease period of vestibular neuritis 19 patients previously examined at our department were given a questionnaire about whether they had experienced any audiovestibular symptoms since they first fell ill. All 19 patients responded and 18 consented to participate in the long-term follow-up...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180243
更新日期:1999-01-01 00:00:00
abstract::Eight patients with dystrophia myotonica (Steinert) were studied. They all had myotonia and pathological EMG and in some cases other signs of the disease. The 50% relaxation times of the stapedius reflex were significantly prolonged compared with a control group of 40 healthy, young subjects with normal hearing and no...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128937
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the capability of indirect computed tomography and magnetic resonance lymphography (CT/MR-LG) with gadolinium-loaded, polyethylenimine-entrapped gold nanoprobes (Gd-Au PENPs) for assessing lingual sentinel lymph node (SLN) metastasis in a tongue VX2 carcinoma model. MATERIALS AND METHODS:Seventee...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1441544
更新日期:2018-08-01 00:00:00
abstract:CONCLUSION:Vibrant Soundbridge (VSB) application to the middle ear windows yields better functional outcomes than conventional hearing aids. However, speech discrimination scores obtained with VSB and conventional hearing aids are similar. OBJECTIVE:To assess audiological outcomes of round and oval window applications...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.702353
更新日期:2012-12-01 00:00:00
abstract::Fifteen normal speakers (7 women and 8 men), ranging in age from 21 to 35 years, were examined consecutively with rigid telescopy and flexible fiberscopy during sustained phonation at 3 loudness levels. The endoscopes were connected to a stroboscope and video equipment. The purpose was to investigate whether the two l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209100796
更新日期:1992-01-01 00:00:00
abstract:CONCLUSIONS:A large set of mucin genes is expressed in nasal polyps. The expression pattern is complex and may reflect the wide spectrum of variables involved in polyp formation and progression. Prospective studies including subgroups of nasal polyps and involving substantial numbers of cases in each subgroup will be r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510027538
更新日期:2005-06-01 00:00:00
abstract::45CaCl2 was injected into gerbils in single or multiple doses, and the resulting radioactivity in serum, otoconial CaCO3, bone samples, and selected labyrinthine epithelium was determined by liquid scintillation spectrometry. Incorporation into both utricular and saccular otoconia occurred at the rate of 0.06-0.07 nmo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121327
更新日期:1975-09-01 00:00:00
abstract::Lymphangioscopical and ultrastructural studies of the larynx reveal a lymphatic capillary and a collecting vessel system. Collecting vessels show luminal valves and elastic structural components within the wall. Lymphangioscopy reveals that a strict compartmentation of different laryngeal areas is unjustifiable with t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127137
更新日期:1980-03-01 00:00:00
abstract:CONCLUSION:Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1170878
更新日期:2016-09-01 00:00:00
abstract:CONCLUSIONS:We describe a Japanese family with high-frequency sensorineural hearing loss (SNHL) harboring a c.211delC mutation in the KCNQ4 gene. Families showing progressive high-frequency SNHL should be investigated for mutations in the KCNQ4 gene. OBJECTIVE:To determine the responsible deafness gene in a Japanese f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.890740
更新日期:2014-06-01 00:00:00