Abstract:
BACKGROUND:To identify the difference of surgical margin and recurrence status of early stage tongue carcinoma via wide excision in a single institution with and without free flap reconstruction. OBJECTIVE:Survey whether the reconstruction methods for early tongue cancer affects disease control, survival outcomes. METHODS:This was a retrospective study and patients with early tongue cancer underwent surgery via tumor ablation with (group 1 = 56) or without free flap reconstruction (group 2 = 291). RESULTS:The percentage of patients with free margin less than 5 mm was higher in the group 2 than in group 1 (49.48% vs. 19.64%, p < .001), as the mean free margin was significantly larger in group 1 than in group 2 (7.88 mm vs. 5.68 mm; p < .001). Despite higher number of T2 stage patients in group 1 (89.29%), the group 1 resulted in a significant lower recurrence rate (p = .024). CONCLUSIONS:The utilization of free flap reconstruction for early stage tongue cancer achieved a large pathologic free margin and had relative lower recurrence and good survival rates.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Lu CC,Tsou YA,Hua CH,Tsai MHdoi
10.1080/00016489.2018.1490030subject
Has Abstractpub_date
2018-10-01 00:00:00pages
945-950issue
10eissn
0001-6489issn
1651-2251journal_volume
138pub_type
杂志文章abstract:CONCLUSION:The data suggest that histamine up-regulates MUC2 gene regulation and mucin production in airway epithelial cells through histamine 1 receptor (H1R). Histamine appears to play an important role in the early phase of mucin regulation, which might be effectively blocked by an H1R antagonist. OBJECTIVE:Histami...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.661075
更新日期:2012-06-01 00:00:00
abstract:CONCLUSION:Vibrant Soundbridge (VSB) application to the middle ear windows yields better functional outcomes than conventional hearing aids. However, speech discrimination scores obtained with VSB and conventional hearing aids are similar. OBJECTIVE:To assess audiological outcomes of round and oval window applications...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.702353
更新日期:2012-12-01 00:00:00
abstract::Explants of basilar papillae from 6-7 days posthatch chicks were cultured in growth medium for a period of 1-8 days. Hair cells were counted following staining of stereocilia bundles with FITC-phalloidin, and the percentage of hair cell survival was determined by comparison to control (i.e. uncultured) specimens. Hair...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850183133
更新日期:1998-09-01 00:00:00
abstract::The inner ear responds immunologically to foreign proteins and pathogens introduced into the cochlea. The route of entry of the cells participating in the inner ear inflammatory process is the spiral modiolar vein with its collecting venules. Since this vein is located adjacent to the scala tympani, the end result of ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489009107455
更新日期:1990-11-01 00:00:00
abstract:CONCLUSION:The risk of operation-requiring postoperative bleeding after abscess tonsillectomy is no different from the risk after elective tonsillectomy. However, the risk is higher for older than for younger patients, both for the whole cohort and for tonsillectomy à chaud. OBJECTIVE:The objective of the present stud...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.660545
更新日期:2012-07-01 00:00:00
abstract::Olfactory and respiratory epithelia was prepared for thin-section and freeze-fracture replicas, and were investigated using electron microscopy. Three cell types were identified in the olfactory epithelium: olfactory receptor neurons (ORN), sustentacular cells (SC) and basal cells (BC); and respiratory epithelial cell...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909125526
更新日期:1989-09-01 00:00:00
abstract::Primary afferent projections from singular parts of the vestibular labyrinth were studied in the guinea pig. The posterior ampullary nerve, the common trunk of the anterior and lateral ampullary nerves, as well as fibers innervating the macula sacculi or the macula utriculi were traced with crystals of horseradish per...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137430
更新日期:1992-01-01 00:00:00
abstract::The transitional zone of the saccule and the utricle--has been studied by transmission electron microscope in rats, days before birth. A noticeable secretory activity has been observed in their cells as well as the presence of inorganic spicular bodies that have also been observed in the lumen, some of them integrated...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309139436
更新日期:1983-05-01 00:00:00
abstract::Lymphangioscopical and ultrastructural studies of the larynx reveal a lymphatic capillary and a collecting vessel system. Collecting vessels show luminal valves and elastic structural components within the wall. Lymphangioscopy reveals that a strict compartmentation of different laryngeal areas is unjustifiable with t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127137
更新日期:1980-03-01 00:00:00
abstract:CONCLUSION:This study showed that elective neck dissection (ND) resulted in reduced regional recurrences in a selected group of surgically treated patients with pT1-2 carcinomas but did not show any benefit for disease-specific survival (DSS). Furthermore, the importance of pN classification was also verified for this ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.743032
更新日期:2013-03-01 00:00:00
abstract::Characteristic patterns of laryngeal dysfunction due to central neurologic disease are documented by 16 mm ciné photography. Representative patients are used to describe typical patterns of abnormal laryngeal function which occur in upper motor neuron, extrapyramidal, cerebellar, nuclear and mixed foci of lesions. The...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109138516
更新日期:1981-05-01 00:00:00
abstract::The basement membrane zone (BMZ) of the epithelium of the vocal folds was investigated electron microscopically in 10 patients suffering from various benign lesions and in 3 controls. Various defects were observed: a thickening by deposition of electron dense material, a loss of normal architecture, and a near absence...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135774
更新日期:1993-01-01 00:00:00
abstract:CONCLUSION:Videomicroscopy with subpixel analysis is an excellent system for quantification of outer hair cell (OHC) movements. The resolution of a few nanometers is accurate enough to show induced differences of electromotility. OBJECTIVE:Electromotility of OHCs is a voltage-dependent process resulting from a membran...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701411502
更新日期:2008-03-01 00:00:00
abstract::The maintenance of upright stance in humans requires the integrative evaluation of vestibular, visual, and proprioceptive information. Recent experiments prove the existence of fast vestibulo-spinal reactions in humans. Their physiological significance for the compensation of sudden external displacements of the body ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127518
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND:Efficacy of current treatment methods in idiopathic sudden sensorineural hearing loss (ISSNHL) is still unsatisfactory. OBJECTIVE:This study aimed to discover in differences in effect between steroid applications responsible for promoting the prognosis in ISSNHL. MATERIALS AND METHODS:A study was conducted...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1504170
更新日期:2018-11-01 00:00:00
abstract::This study was designed to investigate properties of laryngeal secretion and secretory activity of IgA in the larynx. Laryngeal secretions were collected by adsorption method on filter paper during laryngomicrosurgery from 20 patients having an inflammatory lesion in the larynx. Contents of IgG, IgA, IgE, secretory co...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126397
更新日期:1979-01-01 00:00:00
abstract::A time-sequence study was made of the early ultrastructural changes of the stria vascularis and Reissner's membrane in the guinea pig after obliteration of the endolymphatic sac and duct. Pathological alterations of both the stria vascularis and Reissner's membrane were found to start in the apex of the cochlea. The m...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107319
更新日期:1987-09-01 00:00:00
abstract::The three-dimensional distribution of the cricoid area was investigated using computer graphics and its histological structure and pathology were studied using whole-organ serial sections. A total of 26 adult human larynges were examined. The findings were as follows: 1. Cricoid areas were located along the superior p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract::Glyconjugate expression in formalin-fixed, paraffin-embedded Sjögren's syndrome labial glands (nine cases) was compared with that in normal glands (12 samples) using a wide panel of lectins. Mucous cells expressed mainly mucous-type glycoproteins including sialyl, fucosyl, galactosyl and galactosaminosyl residues, and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709114217
更新日期:1997-11-01 00:00:00
abstract::Cells can die by two distinct pathways: apoptosis and necrosis. To explore whether intense noise can induce hair cell (HC) death via the apoptotic pathway, we systematically examined morphological changes in guinea pig cochlear HC nuclei stained with Hoechst 33342, a fluorescent dye specifically labelling the nuclear ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:CONCLUSIONS:The facial nerve courses shown by preoperative CT imaging coincide with the surgical findings in most congenital aural atresia cases. CT scanning is critical in evaluation of a patient's candidacy for atresia surgery. OBJECTIVES:To evaluate the diagnostic value of preoperative CT scanning of the facial ner...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480801953064
更新日期:2008-01-01 00:00:00
abstract::Rhinomanometric observations of nasal airway patency were obtained for each nasal passage every 10 min throughout an uninterrupted 8-h session. The 49 airflow observations for each nasal passage were subjected to autocorrelation analysis, a statistical technique for quantifying periodicities in a temporal sequence of ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709109065
更新日期:1987-07-01 00:00:00
abstract::The spiral ganglion from white cats with hereditary deafness has been studied with the transmission electron microscope, and comparisons made with hearing animals at different ages. Ganglion cell loss occurs secondary to destruction of the organ of Corti, but only after the lapse of several months. Prior to neuronal l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009131737
更新日期:1980-11-01 00:00:00
abstract::Central origin of the vidian nerve in the dog was investigated using the retrograde tracing technique of horseradish peroxidase (HRP). After HRP was applied to the vidian nerve, labelled neurons were found in the medulla oblongata and the geniculate ganglion but could not be found in the trigeminal ganglion. Labelled ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309132883
更新日期:1983-07-01 00:00:00
abstract::Different analysis methods for the objective measurements of body sway were examined to establish the most sensitive method for identifying changes in stability. Changes between stability with eyes open and eyes closed were used to assess the techniques. Body sway was measured in a group of normal subjects standing on...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126028
更新日期:1994-03-01 00:00:00
abstract::Acid base balance changes were observed during 72 h following bilateral nasal obstruction in rats. Mouth breathing caused acute respiratory acidosis and marked aerophagia, leading to spontaneous death of the experimental animal 80 to 90 h postoperatively. Stenotic oropharyngeal airway, due to palatal-epiglottic approx...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137406
更新日期:1991-01-01 00:00:00
abstract:CONCLUSION:Chances of hearing preservation are better in patients with vestibular schwannoma (VS) from the superior vestibular nerve (SVN) than from the inferior vestibular nerve (IVN). Pathologic posturography and electronystagmography (ENG) findings are more common in schwannomas from the SVN compared with tumors fro...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.536991
更新日期:2011-05-01 00:00:00
abstract::In 82 patients with acute tonsillitis studied, beta-hemolytic group A streptococci were isolated from 30 (37%), and group C or G streptococci from 12 (15%). In the 40 patients with non-streptococcal tonsillitis there was a significantly higher isolation rate of pneumococci, H. influenzae and/or B. catarrhalis, as comp...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107339
更新日期:1987-09-01 00:00:00
abstract::Background: Frequency-specific hearing studies are important for predicting hearing results and the prognosis after stapes surgery, to prepare for the rehabilitation of frequency-specific hearing in patients with otosclerosis.Objectives: To evaluate outcomes of stapes surgery of Chinese otosclerosis patients with diff...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1724331
更新日期:2020-05-01 00:00:00
abstract:CONCLUSIONS:In addition to the correlation of transforming growth factor (TGF)-beta1 levels to the radiation toxicity, both Epstein-Barr virus (EBV) infection and postoperative status play roles in the change in plasma TGF-beta1 levels in patients with head and neck cancers. OBJECTIVES:To assess the parameters involve...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701714293
更新日期:2008-10-01 00:00:00