Abstract:
:The embryonic development of the crista ampullaris of the CBA/CBA mouse was followed both in organ culture of explanted inner ears of the 16th gestational day and in vivo from the 16th gestational day until the 21st day, an age corresponding to birth. Cytodifferentiation of the sensory epithelium of the crista ampullaris occurs during this period. At partus, there is a rather mature crista with well developed hair cells and 1-2 layers of supporting cells. Innervation and differentiation into type I and type II hair cells have started prior to partus but occur mainly post partum. The in vitro development followed that of the in vivo but with a slight delay, especially concerning the later stages of the in vitro development. At the time corresponding to partus, differentiation of hair cells is almost identical in the two groups but innervation is delayed in the in vitro group of inner ears. Because of the very high reproducibility/stability in vitro and morphologic maturation of both hair cells and gross structure of the crista ampullaris, organ culture of the 16th gestational day inner ear explant is a suitable model in the study of the late embryonic development under normal and pathological conditions.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Nordemar Hdoi
10.3109/00016488309132868subject
Has Abstractpub_date
1983-07-01 00:00:00pages
1-8issue
1-2eissn
0001-6489issn
1651-2251journal_volume
96pub_type
杂志文章abstract:CONCLUSION:The midline electroneurography (ENoG) method might reflect total facial nerve degeneration. OBJECTIVE:We compared ENoG values in patients with facial palsy using two different methods, the midline method and five electroneurogram recordings, to reveal whether the ENoG value obtained with the midline method ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.743680
更新日期:2013-03-01 00:00:00
abstract:CONCLUSION:Vasomotor symptoms (VMS) and especially hot flushes are negatively associated with recovery from menopause-related dizziness. A further study is justified to determine whether hormone replacement therapy (HRT) can shorten this recovery time. OBJECTIVES:This study aimed to compare the rate of recovery from d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.841991
更新日期:2014-02-01 00:00:00
abstract::T lymphocytes from tonsil (To) and peripheral blood (PB) of 4 tonsillectomized children were subjected to clonal expansion with PHA in order to analyze at single cell level their cytolytic activity and their ability to produce interleukins such as IL-2, IFN-gamma and IL-4. Analyzing all T-cell clones (CD4+ and CD8+) o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138439
更新日期:1991-01-01 00:00:00
abstract:CONCLUSION:This study shows that, in cochlear implantation (CI) surgery, pre-operative caloric test results are not correlated with post-operative outcomes of dizziness or speech perception. OBJECTIVES:To determine the role of pre-operative caloric tests in CI. METHODS:The records of 95 patients who underwent unilate...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1172731
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of imagining a fixed spatial reference on balance control. MATERIAL AND METHODS:Twenty-one healthy subjects were asked to remain as stable as possible while standing on a sway-referenced platform (NeuroCom Equitest posturography system). Subjects were instructed to keep their eyes o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017503
更新日期:2004-10-01 00:00:00
abstract:CONCLUSION:GABA-mediated inhibition is responsible for the duration tuning in the inferior colliculus (IC) of guinea pigs, a non-echo-locating mammal. Duration tuning in this species is better demonstrated in an appropriate short time window. OBJECTIVES:To investigate the role of GABA-mediated inhibition in duration t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701840122
更新日期:2008-10-01 00:00:00
abstract:CONCLUSION:Endoscopic surgery improved facial pain/headache and physical-psychosocial impacts in patients with nasal polyposis. However, one fifth of patients still experienced residual pain after surgery, requiring neurologic counseling to look for the non-sinonasal cause of their symptoms. OBJECTIVE:Considering the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1058531
更新日期:2015-01-01 00:00:00
abstract:CONCLUSION:Telephone usage is a difficult challenge for cochlear implanted patients. A significant number of cochlear implanted patients are able to carry on a land-line or mobile telephone conversation. The telephone model may be a critical factor for telephone performance. OBJECTIVES:The goals of this study were to ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500469552
更新日期:2006-07-01 00:00:00
abstract::This study was designed to investigate properties of laryngeal secretion and secretory activity of IgA in the larynx. Laryngeal secretions were collected by adsorption method on filter paper during laryngomicrosurgery from 20 patients having an inflammatory lesion in the larynx. Contents of IgG, IgA, IgE, secretory co...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126397
更新日期:1979-01-01 00:00:00
abstract::Background: Atoh1, also named Math1, is essential for the development of inner ear hair cells. Many studies have confirmed that the absence of Atoh1 resulted in a total loss of inner ear hair cells, which indicates that Atoh1 plays very similar roles in the development of hair cells in the cochlea and vestibule. Objec...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1497855
更新日期:2018-11-01 00:00:00
abstract::Life-threatening cervical complications associated with infectious mononucleosis are rare. The combination of acute epiglottitis and subsequent necrotizing fasciitis of the head and neck in a patient with infectious mononucleosis has not been reported to date.A 47-year-old female with infectious mononucleosis and epig...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510027475
更新日期:2005-10-01 00:00:00
abstract::Six profoundly deaf patients were studied with mapping evoked potentials (MEP) using an acoustic signal passed through the vibrotactile prosthesis. This stimulus produced an activation of the central sulcus brain cortex. When the proSthesis was placed in the presenternal area it showed N1 P1 potentials with higher vol...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709117771
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:As tympanotomy using the transcanal approach was a routine surgical technique for traumatic ossicular disruption, the efficacy of the posterior tympanum approach was rarely explored. AIM:This study aimed to investigate whether the hearing outcomes improved after simultaneous ossiculoplasty and facial nerve ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1833081
更新日期:2020-11-05 00:00:00
abstract::Recent investigations of children with specific language impairment (SLI) have found deviant anatomical asymmetry of the perisylvian cortex. These studies argue that this deviant anatomical asymmetry is linked to the language disorders of SLI children. To date no studies have examined whether deviant functional asymme...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300043929
更新日期:2001-01-01 00:00:00
abstract:CONCLUSIONS:Polytetrafluoroethylene (PTFE) may represent a material that prevents adhesions when implanted in the middle ear. This characteristic can be used to improve the design of prostheses. OBJECTIVE:Prostheses in the middle ear have a relatively high failure rate due to extrusion, deformation and adhesion. Adhes...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500312570
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVES:This study was conducted to demonstrate the safety and efficacy of the Otologics Middle Ear Transducer (MET) Ossicular Stimulator and, in particular, to compare the audiologic benefits of this novel form of electromechanical stimulation with those of conventional acoustical amplification. MATERIAL AND METHO...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016480410016298
更新日期:2004-05-01 00:00:00
abstract::We have developed a new technique for analyzing the rotation vector of eye movement in three dimensions with an infrared CCD camera based on the following four assumptions; i) the eye rotates on a point; ii) the pupil edge is a circle; iii) the distance from the center of eye rotation to pupil circle remains unchanged...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950181882
更新日期:1999-01-01 00:00:00
abstract::The aerobic and anaerobic bacterial flora of middle ear exudate (MEE) of 47 consecutive patients with chronic suppurative otitis media were studied using a quantitative bacteriological technique under strictly anaerobic conditions. Specimens from the external auditory canal (EAC) and the nasopharynx (NP) were obtained...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609119425
更新日期:1986-11-01 00:00:00
abstract:OBJECTIVE:To present the experiences of consumers with traditional hearing aids (T-HAs) and digital signal processing hearing aids (DSP-HAs) during the period 1999-2001, based on data obtained from an ongoing quality assurance programme. MATERIAL AND METHODS:A questionnaire is mailed to subjects fitted with HAs 3-4 mo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001088
更新日期:2003-01-01 00:00:00
abstract::Specimens from the epithelium on the lateral wall of the human nose were examined under the electron microscope using a lipid and carbohydrate retaining method. In many of the ciliated epithelial cells and in some of the cells in the mucosal glands we identified multilamellated granules. These structures resembled lam...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009107447
更新日期:1990-03-01 00:00:00
abstract:CONCLUSION:L-N-Acetylcysteine (L-NAC) significantly reduced reactive oxygen species (ROS) generation and cochlear cell apoptosis after irradiation. The safe and effective use of L-NAC in reducing radiation-induced sensorineural hearing loss (SNHL) should be verified by further in vivo studies. OBJECTIVES:Radiation-ind...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701762490
更新日期:2008-04-01 00:00:00
abstract::To investigate the pathogenesis of swimmers' sinusitis we questioned and examined a group of 20 swimmers and 20 controls. Clinical examination was followed by rhinomanometry, sonography of the maxillary sinuses, a saccharine test to assess mucociliary transport in the nose, and a viable cytological sampling of the nas...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009122550
更新日期:1990-09-01 00:00:00
abstract::Nerves displaying vasoactive intestinal peptide (VIP) immunoreactivity were detected in the upper respiratory tract of guinea pigs, rabbits and cats. VIP nerves were numerous in the cat, less numerous in the rabbit and rare in the guinea pig. In the nasal mucosa, fine varicose VIP nerves were found to surround nasal g...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809107524
更新日期:1978-11-01 00:00:00
abstract:CONCLUSION:Contrast enhancement of the inner ear by three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) taken 4 h after intravenous gadolinium (Gd) injection was better than when taken at 10 min. Using heavily T2-weighted 3D-FLAIR MRI, visualization of endolymphatic hydrops (...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.639085
更新日期:2012-03-01 00:00:00
abstract::A platinum-iridium electrode with a Teflon cover tube was chronically implanted through the round window into the scala tympani of the guinea pig. Animals were sacrificed at 30 to 40 weeks after electrode implantation, and the cochleae were observed by scanning electron microscopy or with light microscopy. The results...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809097005
更新日期:1988-03-01 00:00:00
abstract:CONCLUSION:Cochlear implantation (CI) for Japanese single-sided deafness patients resulted in improved speech perception, increased sound localization accuracy, and reduced tinnitus handicap. OBJECTIVES:This study reports results for five adult SSD cases with CI, focusing on the benefits they obtained in terms of spee...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.3109/00016489.2015.1116046
更新日期:2016-01-01 00:00:00
abstract::In electrocochleography (ECochG) compound action potential (CAP) and summation potential (SP) are usually separated from the cochlear microphonic (CM) by the CM cancellation technique consisting in averaging the responses evoked by rarefaction and condensation clicks. With the aim of analysing the ECochG responses evo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000892
更新日期:2000-03-01 00:00:00
abstract::Little is known about the physiologic regulation of the vestibular end organ blood flow. The purpose of the current study was to examine posterior semicircular canal ampulla blood flow in addition to systemic factors during intravenous infusions of calcitonin-gene related peptide (CGRP), a factor involved in the tonic...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709114207
更新日期:1997-11-01 00:00:00
abstract::A family with early-onset vestibulopathy is presented. The 34-year-old father had experienced brief attacks of vertigo and currently suffers from unsteadiness and oscillopsia during head movements. His two young sons also experience brief attacks of spontaneous vertigo. In vestibular testing all three subjects showed ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310002500
更新日期:2003-08-01 00:00:00
abstract::The present morphological study was designed to investigate the expression of HLA class II subregion gene products on human trachea. Frozen sections from the tracheas of 20 cadavers not suffering from ear, nose or throat diseases were studied immunohistochemically using monoclonal antibodies which recognize monomorphi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009122530
更新日期:1990-07-01 00:00:00