Absence of Atoh1 induced partially different cell fates of cochlear and vestibular sensory epithelial cells in mice.

abstract：CONCLUSION:Systemic application of human mesenchymal stem cells (hMSCs) may be another effective tool for stem cell supply to the inner ear. OBJECTIVES:Most researchers have used local application to provide the inner ear with stem cells. In spite of their efficacy, these methods can potentially cause irreversible dam...

journal_title：Acta oto-laryngologica

authors： Choi BY,Song JJ,Chang SO,Kim SU,Oh SH

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Traumatic tympanic membrane perforation (TTMP) is usually managed conservatively because most close spontaneously within a few months. Nevertheless, spontaneous closure of TTMP during long-term observation has not been well described in the literature. OBJECTIVES:The present study investigated factors assoc...

journal_title：Acta oto-laryngologica

authors： Tachibana T,Kariya S,Orita Y,Makino T,Haruna T,Matsuyama Y,Komatsubara Y,Naoi Y,Nakada M,Noda Y,Sato Y,Nishizaki K

更新日期：2019-06-01 00:00:00

abstract：:Background: Odontogenic sinusitis (OS) is a common but underdiagnosed form of acute rhinosinusitis (ARS). OS carries no specific characteristics, but unilateral symptoms and certain microbiological as well as radiological findings indicate odontogenic origin. Aims/objectives: We studied the proportion of OS in ARS pat...

journal_title：Acta oto-laryngologica

authors： Wuokko-Landén A,Blomgren K,Välimaa H

更新日期：2019-09-01 00:00:00

abstract：:The penetration of oral erythromycin stearate (Abboticin), administered in a dosage of 500 mg three times a day, into the maxillary sinus mucosa and secretion was studied in 15 patients (22 sinuses) operated on for chronic maxillary sinusitis. The average concentration in serum was 2.3 microgram/ml, 1.2 microgram/ml i...

journal_title：Acta oto-laryngologica

authors： Paavolainen M,Kohonen A,Palva T,Renkonen OV

更新日期：1977-09-01 00:00:00

abstract：OBJECTIVES:This study was conducted to demonstrate the safety and efficacy of the Otologics Middle Ear Transducer (MET) Ossicular Stimulator and, in particular, to compare the audiologic benefits of this novel form of electromechanical stimulation with those of conventional acoustical amplification. MATERIAL AND METHO...

journal_title：Acta oto-laryngologica

authors： Jenkins HA,Niparko JK,Slattery WH,Neely JG,Fredrickson JM

更新日期：2004-05-01 00:00:00

abstract：:Smooth pursuit responses to sinusoidal and triangular waveform targets were investigated in elderly and middle-aged subjects. The middle-aged pursued triangular targets with significantly lower gain than sinusoidal targets. In the elderly, pursuit gain was significantly lower than in the middle-aged under all target c...

journal_title：Acta oto-laryngologica

authors： Zackon DH,Sharpe JA

更新日期：1987-09-01 00:00:00

abstract：CONCLUSION:Idiopathic otolithic vertigo (IOV) with relatively long duration of attacks might be caused by endolymphatic hydrops in the otolith organ. OBJECTIVES:To clarify the pathophysiology underlying IOV, episodic tilting or translational sensation attacks by unknown causes, especially the possibility of endolympha...

journal_title：Acta oto-laryngologica

authors： Murofushi T,Komiyama S,Hayashi Y,Yoshimura E

更新日期：2015-01-01 00:00:00

abstract：:Blood circulation in the cochlear lateral wall after exposure to a non-physiological level of sound (120-125 dB SPL, 3 h) was investigated immunohistologically. Kanamycin (KM), which was expected to function as a tracer of blood flow, was administered to guinea pigs 5 min to 21 h after sound termination. At 5-30 min, ...

journal_title：Acta oto-laryngologica

authors： Yamane H,Nakai Y,Konishi K,Sakamoto H,Matsuda Y,Iguchi H

更新日期：1991-01-01 00:00:00

abstract：:Cells can die by two distinct pathways: apoptosis and necrosis. To explore whether intense noise can induce hair cell (HC) death via the apoptotic pathway, we systematically examined morphological changes in guinea pig cochlear HC nuclei stained with Hoechst 33342, a fluorescent dye specifically labelling the nuclear ...

journal_title：Acta oto-laryngologica

authors： Hu BH,Guo W,Wang PY,Henderson D,Jiang SC

更新日期：2000-01-01 00:00:00

abstract：CONCLUSION:Nasal obstruction, rhinorrhea, and the amount of rhinorrhea that confidently reflect the parasympathetic stimulation can be used to more precisely predict nonspecific nasal hyper-reactivity (NHR). OBJECTIVE:We aimed to identify factors that confidently reflected the presence and the degree of NHR, measured ...

journal_title：Acta oto-laryngologica

authors： Kim YH,Jang TY

更新日期：2012-10-01 00:00:00

abstract：:In precollicular decerebrate cats, activation of limb extensors during side-down roll tilt of the animal depends on both an increased discharge of excitatory vestibulospinal neurons and a reduced discharge of inhibitory medullary reticulospinal (mRS) neurons. These inhibitory neurons are tonically excited by a choline...

journal_title：Acta oto-laryngologica

authors： Pompeiano O,Stampacchia G,Horn E,d'Ascanio P

更新日期：1987-05-01 00:00:00

abstract：:In a previous paper we demonstrated physiologically a sensitive period for acoustic trauma in the rat pup cochlea, with a maximum at 22 days of age. Seven or 60 days after noise exposure these 22-day exposed rats were used for light and electron microscopy. At 7 days, surface preparation revealed restricted damage to ...

journal_title：Acta oto-laryngologica

authors： Lenoir M,Pujol R

更新日期：1980-03-01 00:00:00

abstract：CONCLUSIONS:The critical stage for cochlear gene regulation in the embryo is E49-E56. These data provide a valuable resource to help elucidate gene regulation in cochlear development and will benefit ear-related studies, especially those that focus on gene and stem cell therapies in hearing loss. OBJECTIVES:To investi...

journal_title：Acta oto-laryngologica

authors： Wang Q,Zhang Y,Guo W,Liu Y,Wei H,Yang S

更新日期：2017-11-01 00:00:00

abstract：CONCLUSION:The curative effect in the group where facial-facial anastomosis (FFA) was delayed for 7 days was similar to that in the immediate FFA group and had a better repair within 60 days. OBJECTIVE:Due to the uncertainty about optimal timing of delayed facial nerve repair, we designed an experimental study in guin...

journal_title：Acta oto-laryngologica

authors： Hu J,Zhou L,Ma Z

更新日期：2013-07-01 00:00:00

abstract：:Several studies have reported variations in shape and size of stereociliary bundles and in a limited number of observations have associated them to type I and type II hair cells. A systematic study has been undertaken for which a technique was developed in order to identify both cell types and their corresponding hair...

journal_title：Acta oto-laryngologica

authors： Lapeyre P,Guilhaume A,Cazals Y

更新日期：1992-01-01 00:00:00

abstract：:We established new cell lines from head and neck cancer patients for studies of adhesion molecules and cellular behavior in nine patients with primary or metastatic cancer treated at the Asan Medical Center. Explant cultures of fresh tumor tissue were used to develop new permanent tumor cell lines. Lines were tested f...

journal_title：Acta oto-laryngologica

authors： Kim SY,Chu KC,Lee HR,Lee KS,Carey TE

更新日期：1997-09-01 00:00:00

abstract：:Background: Intratympanic and intravenous gadolinium administration is used to visualise endolymphatic hydrops. Aims/objectives: The goal of this study was to compare the image quality between intratympanic (IT-method) and intravenous (IV-method) gadolinium administration using three-dimensional inversion recovery wit...

journal_title：Acta oto-laryngologica

authors： Li Y,Sha Y,Wang F,Lu P,Liu X,Sheng Y,Zhang Z,Liu M

更新日期：2019-08-01 00:00:00

abstract：:Specimens from the epithelium on the lateral wall of the human nose were examined under the electron microscope using a lipid and carbohydrate retaining method. In many of the ciliated epithelial cells and in some of the cells in the mucosal glands we identified multilamellated granules. These structures resembled lam...

journal_title：Acta oto-laryngologica

authors： Svane-Knudsen V,Rasmussen G,Clausen PP

更新日期：1990-03-01 00:00:00

abstract：:In 12 healthy volunteers, and 5 prelingually and 5 postlingually profoundly deaf subjects, a 500 Hz filtered click stimulus was applied to the mastoid via the bone conductor. In all the healthy volunteers, middle latency response (MLR) was recorded. Among all profoundly deaf subjects, MLR was recorded only in 2 with p...

journal_title：Acta oto-laryngologica

authors： Ribarić K,Padovan I,Prevec TS

更新日期：1985-03-01 00:00:00

abstract：:This study was performed in order to determine the immunohistochemical expression and distribution pattern as well as the electrophysiological actions of substance P in human vestibular ganglion cells. Substance P-like immunostaining was mainly found in the cytoplasm of small vestibular ganglion cells. In contrast, ne...

journal_title：Acta oto-laryngologica

authors： Felix H,Schickinger B,Felix D

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of imagining a fixed spatial reference on balance control. MATERIAL AND METHODS:Twenty-one healthy subjects were asked to remain as stable as possible while standing on a sway-referenced platform (NeuroCom Equitest posturography system). Subjects were instructed to keep their eyes o...

journal_title：Acta oto-laryngologica

authors： Gianna-Poulin C,Wood S,Brock M,Black FO

更新日期：2004-10-01 00:00:00

abstract：CONCLUSION:Speech thresholds measured using Cantonese Hearing in Noise Test (CHINT) and cortical evoked response audiometry (CERA) thresholds were highly correlated with pure-tone behavioral results. Both tests are considered to provide good estimates of hearing thresholds and can be employed to confirm the degree of h...

journal_title：Acta oto-laryngologica

authors： Wong LL,Cheung C,Wong EC

更新日期：2008-06-01 00:00:00

abstract：CONCLUSION:Our findings suggest that there exists a Na(+) transport system in the cochlea consisting of SGK1, Nedd4 isoforms and ENaC, which may work in concert to transport Na(+) and to maintain homeostasis in the inner ear as they do in other tight epithelia. OBJECTIVES:It has been well demonstrated that the epithel...

journal_title：Acta oto-laryngologica

authors： Zhong SX,Liu ZH

更新日期：2009-09-01 00:00:00

abstract：:The influence of obstructed nasal passages was investigated in l4 patients with allergic rhinitis. Disordered breathing in sleep was found in all patients in the form of periodic breathing, and hypopneic and hyperpneic episodes, associated with characteristic "microarousals' from sleep. Patients had an average of 50 "...

journal_title：Acta oto-laryngologica

authors： Lavie P,Gertner R,Zomer J,Podoshin L

更新日期：1981-11-01 00:00:00

abstract：:We evaluated the vestibulo-ocular reflex (VOR) in 50 normal human subjects, uniformly distributed in age 20-59 years, and evenly distributed in sex by decade, using sinusoidal rotation over the frequency range of 0.005 to 1.0 Hz and three peak amplitudes of 25, 50, and 100 deg/sec. Age variations. The gain magnitude o...

journal_title：Acta oto-laryngologica

authors： Wall C 3rd,Black FO,Hunt AE

更新日期：1984-09-01 00:00:00

abstract：CONCLUSIONS:Our results confirm that supracricoid laryngectomies (SL) are reliable techniques for glottosupraglottic tumors, even for selected T3 and T4 cases, if the indications are correct. These surgical techniques allow a good quality of life with the preservation of the larynx. OBJECTIVE:SL with cricohyoidoepiglo...

journal_title：Acta oto-laryngologica

authors： Laudadio P,Presutti L,Dall'olio D,Cunsolo E,Consalici R,Amorosa L,Cancellieri A,Bocciolini C

更新日期：2006-06-01 00:00:00

abstract：CONCLUSION:Early intervention may change the natural course of allergic rhinitis, preventing the progression to asthma. In particular, immunotherapy guarantees remission of local symptoms and valid protection against local and bronchial complications. Symptomatic treatment represents a valid alternative; it is always t...

journal_title：Acta oto-laryngologica

authors： Passali GC,Bellussi LM,De Corso E,Passali FM,Passali D

更新日期：2013-11-01 00:00:00

abstract：:The microsphere method was used to measure the inner ear blood flow in albino rabbits before and during artificial ventilation with 5% CO2 in air. An increase in blood flow resulted in both the cochlear and the vestibular parts of the inner ear. ...

journal_title：Acta oto-laryngologica

authors： Larsen HC,Angelborg C

更新日期：1987-01-01 00:00:00

abstract：CONCLUSIONS:Patients with sudden hearing loss and dizziness after barotrauma should be suspected of barotraumatic perilymph fistula (PLF). Early surgical repair of PLF showed better hearing outcomes. Therefore, diagnostic criteria should help surgical indications of barotraumatic PLF. OBJECTIVES:The aim of this study ...

journal_title：Acta oto-laryngologica

authors： Choi JE,Moon IJ,Kim H,Lee K,Cho YS,Chung WH

更新日期：2017-01-01 00:00:00

abstract：:The tonsils are mucosa-associated lymphoid organs. Several details regarding their normal function and pathological alteration are still unknown. In this review the relationship of the tonsils to similar lymphoid organs is discussed, the possibilities of antigen uptake (M cells and micropores of the crypt epithelium) ...

journal_title：Acta oto-laryngologica

authors： Surján L Jr

更新日期：1987-05-01 00:00:00