Immunohistochemical and electrophysiological demonstration of substance P in human vestibular ganglion cells.

Abstract:

:This study was performed in order to determine the immunohistochemical expression and distribution pattern as well as the electrophysiological actions of substance P in human vestibular ganglion cells. Substance P-like immunostaining was mainly found in the cytoplasm of small vestibular ganglion cells. In contrast, nerve fibers were not labeled. Using intracellular recording techniques, substance P produced a slow depolarization of membrane potentials accompanied by an increase in membrane resistance. Furthermore, an enhanced firing response to depolarization occurred.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Felix H,Schickinger B,Felix D

doi

10.3109/00016489609137839

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

273-6

issue

2

eissn

0001-6489

issn

1651-2251

journal_volume

116

pub_type

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