Substance P nerve fibres in the canine larynx by PAP immunohistochemistry.

Abstract:

:The distribution of the Substance P (SP) immunoreactive nerve fibres in the canine larynx and laryngeal nerves was studied by PAP immunohistochemistry. Many individual SP immunoreactive nerve fibres with varicosities were observed within the epithelial layer and in the connective tissue below the epithelium of the laryngeal mucosa. Small numbers of SP immunoreactive nerve fibres were also found in the submucosal gland region and some of them appeared to terminate in glandular cells. These findings are consistent with the view that SP might be involved in the laryngeal sensory innervation system and the laryngeal glandular secretion. No SP immunoreactive nerve fibres were found in any intrinsic laryngeal muscles. The recurrent laryngeal nerve and the superior laryngeal nerve contained SP immunoreactive nerve fibres and were considered to lie in the pathway of the SP nerve fibres to the larynx.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Hisa Y,Sato F,Fukui K,Ibata Y,Mizukoshi O

doi

10.3109/00016488509108597

subject

Has Abstract

pub_date

1985-07-01 00:00:00

pages

128-33

issue

1-2

eissn

0001-6489

issn

1651-2251

journal_volume

100

pub_type

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