Abstract:
:From a study of nitric oxide (NO) output in the nose and sinuses it seems that: (i) the results obtained regarding the regulation of NO output in the nose do not necessarily apply to the sinuses; (ii) the results obtained for one group of sinuses may not apply to another; and (iii) NO output in the sinuses does not behave as one would expect if it serves to protect against infection.A pilot study was undertaken in one subject to determine whether the control of NO output in the nose differs from that in the sinuses.NO output was measured by aspirating different gaseous concentrations of oxygen (and/or carbon dioxide) through the nasal airways or punctured maxillary and frontal sinuses before and after i.v. administration of L-arginine (20 mg/kg). In the absence of gaseous oxygen in the nose or maxillary antrum, the effect of L-arginine on NO output was the same as that in the presence of oxygen. In the frontal sinus, the effect of L-arginine on NO output was blocked by the absence of gaseous oxygen. NO output in the nose and frontal sinus showed similar changes after either i.v. administration of L-arginine or removal of oxygen from the air. NO output in the maxillary antrum was virtually unaffected by either procedure. NO output in the nose was largely unaffected by the gaseous carbon dioxide content but that in the frontal and maxillary sinuses was profoundly inhibited by it. In both sinuses, suppression of NO output by carbon dioxide was countered by oxygen. Alterations in the oxygen or carbon dioxide content of the maxillary antrum did not alter NO output in the frontal sinus, or vice versa. After i.v. infusion of L-arginine, nasal NO output remained elevated for >1 h.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Qian W,Mäkitie AA,Witterick I,Haight JSdoi
10.1080/00016480510031524subject
Has Abstractpub_date
2005-10-01 00:00:00pages
1080-5issue
10eissn
0001-6489issn
1651-2251pii
RHDYQK1JW7PCVA1Ejournal_volume
125pub_type
杂志文章abstract::The distribution of vascular endothelial growth factor (VEGF), one of the most important angiogenic factors, and microvessel density (MVD) were assessed in laryngeal carcinomas by means of immunohistochemistry. Correlation of VEGF with MVD and clinical parameters (T stage, N stage, histological grading, survival, recu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180711
更新日期:1999-01-01 00:00:00
abstract::In previous studies, sinus secretions have been analysed concerning pO2, pCO2 and pH. In this study the energy metabolism in the maxillary sinus mucosa and secretion was studied in 33 New Zealand White rabbits. In freeze-dried samples, glucose and lactate were analysed by enzymatic assays and ATP by HPLC. In the purul...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809122271
更新日期:1988-11-01 00:00:00
abstract:CONCLUSION:Telephone usage is a difficult challenge for cochlear implanted patients. A significant number of cochlear implanted patients are able to carry on a land-line or mobile telephone conversation. The telephone model may be a critical factor for telephone performance. OBJECTIVES:The goals of this study were to ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500469552
更新日期:2006-07-01 00:00:00
abstract::The properties of the vestibulo-ocular reflex (VOR) were examined during sinusoidal passive head rotation in the dark at 1/6 Hz, in 9 normal subjects and 14 unilateral vestibular patients. Rotation speeds ranged from 90 to 180 degrees/s. The bias (offset of slow-phase velocity from zero) and gain in the VOR were estim...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139351
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to demonstrate the long-term effectiveness of Expansion Sphincter Pharyngoplasty (ESP) as a standalone surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients through a prospective multi-center study. MATERIAL AND METHODS:A prospective non-com...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2018.1533992
更新日期:2019-02-01 00:00:00
abstract::A time-sequence study was made of the early ultrastructural changes of the stria vascularis and Reissner's membrane in the guinea pig after obliteration of the endolymphatic sac and duct. Pathological alterations of both the stria vascularis and Reissner's membrane were found to start in the apex of the cochlea. The m...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107319
更新日期:1987-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the long-term (24 months) clinical performance (vocal fold function) and safety of hylan B gel as compared with bovine cross-linked collagen in the treatment of patients with glottal insufficiency. MATERIAL AND METHODS:In a prospective trial, 70 patients with glottal insufficiency due to unilate...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/00016480410017701
更新日期:2004-12-01 00:00:00
abstract::Normal subjects were exposed to two kinds of optokinetic stimulation, viz. at speeds of 60 degrees/s and 90 degrees/s preceded by acceleration at 6 degrees/s2 and 4.5 degrees/s2, respectively. In most subjects the speed of the eye in the slow nystagmus phase equalled the speed of the rotating device during the acceler...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123954
更新日期:1977-09-01 00:00:00
abstract::The author presents a study of the personality structure, youth development and the role of interhuman conflicts in the work situation and the family, in the causation and course of Menière's disease, the somatopsychic reactions of the patients to the illness, and the principles of a form of psychotherapy which was co...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309139423
更新日期:1983-05-01 00:00:00
abstract:CONCLUSION:The results show that the DUET2 offers users speech perception that is equivalent to or better than the DUET. Moreover, the DUET2 offers subjective benefits above those provided by the DUET. BACKGROUND:The DUET is a combination of hearing aid and CI in one device for electric acoustic stimulation. Since its...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1050605
更新日期:2015-01-01 00:00:00
abstract::An X-ray energy dispersive analysis was performed on the mature serial sectioned freeze-dried mammalian labyrinth (CBA/CBA mouse). The elemental distribution in the endolymphatic and perilymphatic spaces revealed similar results as have been reported in the literature when withdrawing fluid for microanalysis. The cupu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009131744
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND:Benign paroxysmal positional vertigo (BPPV) is the most common type of peripheral vertigo. This study aimed to evaluate the effects of the Semont maneuver (SM) for BPPV treatment, compared with other methods. METHODS:Studies were selected in relevant databases under pre-defined criteria up to June 2015. The...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,meta分析
doi:10.1080/00016489.2016.1212265
更新日期:2017-01-01 00:00:00
abstract::The occurrence of horizontal jerks with larger amplitudes than on Earth was observed during vertical optokinetic nystagmus in astronauts tested throughout a 7-day spaceflight. During early exposure to microgravity, a horizontal spontaneous-like nystagmus was recorded in darkness following both vertical and horizontal ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009107432
更新日期:1990-03-01 00:00:00
abstract:CONCLUSION:MCT is a useful tool to pre-operatively determine whether internal nasal valve (INV) narrowing affects a nasal obstruction. Functional rhinoplasty seemed to produce better results than septoplasty in Asian patients with a nasal obstruction, due to INV narrowing. OBJECTIVE:This study compared pre-operative m...
journal_title:Acta oto-laryngologica
pub_type: 评论,杂志文章
doi:10.3109/00016489.2015.1108523
更新日期:2016-01-01 00:00:00
abstract:CONCLUSION:The necessity of considering cervical tuberculous lymphadenitis (CTL) should be emphasized even today for the differential diagnosis of cervical lymphadenopathy, particularly when it is located in the posterior triangle and supraclavicular regions even in patients without active pulmonary tuberculosis (PTB)....
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.789927
更新日期:2013-09-01 00:00:00
abstract::The three-dimensional distribution of the cricoid area was investigated using computer graphics and its histological structure and pathology were studied using whole-organ serial sections. A total of 26 adult human larynges were examined. The findings were as follows: 1. Cricoid areas were located along the superior p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:CONCLUSION:Contrary to our expectation, that the clinical characteristics of temporal bone fracture would differ in children and adults, we found that the two groups were similar. OBJECTIVES:Most studies of temporal bone fractures have been performed in adults. To our knowledge, no study has investigated differences i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.754995
更新日期:2013-05-01 00:00:00
abstract::The formation of otoconia in the endolymphatic sac (ES) of the larval newt, Cynops pyrrhogaster, has been studied by light and transmission electron microscopy. Some of the epithelial cells of the ES contain an abundance of swollen vesicles, Golgi complexes, rough endoplasmic reticula and ribosomes at the late larval ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850154694
更新日期:1998-07-01 00:00:00
abstract::The objective of this study was to determine whether methylcobalamin inhibits the ototoxic action of gentamicin. Fourteen pigmented guinea pigs were randomly divided into experimental and control groups. Each animal in the experimental group was given a large single dose of gentamicin (125 mg/kg i.m.), followed by imm...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300102752
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:To investigate the outcome of surgically managed laryngeal carcinoma patients attending an outpatient clinic over a 5-year period. MATERIAL AND METHODS:This was an analytical, retrospective, cross-sectional study. A total of 36 laryngeal carcinoma patients who were managed surgically with or without radiothe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410018070
更新日期:2004-08-01 00:00:00
abstract::Simultaneous monitoring in human subjects on the same ear of eardrum displacement by tympanomanometry, and impedance with the electroacoustic bridge, provided information concerning contraction of the stapedius muscle and its effect on eardrum displacement. Extensive control procedures were employed to elicit only the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609107472
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:The association between type 2 diabetes mellitus (T2DM) and hearing loss has not been fully investigated and there is little information on the effects of pre-diabetes on alterations in auditory function in Chinese subjects. METHODS:The study recruited 51 patients with T2DM, 55 patients with pre-diabetes an...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1422084
更新日期:2018-06-01 00:00:00
abstract::This study was designed to assess the utility of otolith-ocular reflex testing in patients with complete unilateral peripheral vestibular deficits. Ten subjects were given a clinical vestibular test battery (ENG & vertical rotation) and research oriented tests of otolith function including dynamic posturography with h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139392
更新日期:1995-11-01 00:00:00
abstract::Merkel cell carcinoma (MCC) is an uncommon cutaneous neoplasm which arises in adults with a peak incidence in the sixth and seventh decades. MCC most often arises in the head and neck area and extremities. Among head and neck primary sites, auricular MCC has proven to be rare and only 20 cases have been reported in th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.1080/00016480410017503-1
更新日期:2005-02-01 00:00:00
abstract::The gram negative bacteria, nontypable Haemophilus influenzae (NTHi) was used to induce otitis media in a total of 18 chinchillas. Three days post-inoculation, three cohorts of 6 chinchillas each were treated daily for four days with either ceftriaxone, chloramphenicol, or diluent without antibiotics. Middle ear fluid...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709118000
更新日期:1997-01-01 00:00:00
abstract::Ciliogenesis events in human vestibular epithelia develop as an asynchronous process between neighbouring cells, but it is a synchronous one within each sensory cell, presenting the following stages. Initially, the cilia buds appear as stubby cylinders well aligned on the cuticular plate of the presumptive sensory cel...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108931
更新日期:1985-03-01 00:00:00
abstract::The purpose of these studies was to compare the ototoxicity of piretanide to that of furosemide in the chinchilla. Chinchillas weighing 400 to 700 g were anesthetized with ketamine plus pentobarbital. Endocochlear potential (EP) was measured continuously by the round window approach using glass microelectrodes. Pireta...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108608
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVES:Hearing loss after spinal anesthesia has been reported to be related to the transmission of a reduced subarachnoid pressure to the inner ear via the cochlear aqueduct due to loss of spinal fluid. However, there are also some controversies related to this phenomenon, which require systematic investigation. M...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017143
更新日期:2004-12-01 00:00:00
abstract:CONCLUSION:Patients with posterior semicircular canal dehiscence (PSCD) have low frequency conductive hearing loss similar to patients with superior semicircular canal dehiscence (SSCD) secondary to a pathologic third window. OBJECTIVES:PSCD can result in conductive hearing loss, but the magnitude of this hearing loss...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489.2015.1060630
更新日期:2015-01-01 00:00:00
abstract:CONCLUSION:This study demonstrated that five Cx26 mutations (R32H, S199F, 572delT, 631-632delGT, and Y155X) affect gap junction (GJ) functions by causing impaired membrane targeting and aberrant cellular localization, and one mutation (R165W) leads to a constriction of the channel pore with no dye coupling. OBJECTIVE:...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.506885
更新日期:2011-01-01 00:00:00