Impaired membrane targeting and aberrant cellular localization of human Cx26 mutants associated with inherited recessive hearing loss.

abstract：:Although the association between gastroesophageal reflux disease (GERD) and laryngeal disorders in adults is well established there is still a lack of information concerning the true extent of the laryngeal complications of GERD in children. The aim of this study was to determine the laryngeal status of children with ...

journal_title：Acta oto-laryngologica

authors： Zalesska-Krecicka M,Krecicki T,Iwanczak B,Blitek A,Horobiowska M

更新日期：2002-04-01 00:00:00

abstract：:The perilymphatic space of the guinea pig was perfused in situ with artificial perilymph containing [32P] orthophosphate and 3H-glycerol while cochlear microphonic potentials (CM) were monitored. The perfusion of 10 mM gentamicin suppressed CM by 62% within 30 min. 32P-incorporation into phosphatidylinositol bisphosph...

journal_title：Acta oto-laryngologica

authors： Tachibana M,Anniko M,Schacht J

更新日期：1983-07-01 00:00:00

abstract：:The fear of destroying an anticipated growth centre has, with time, induced the postponement of nasal septal operations until adult age. Underdevelopment of the nose and middle face is otherwise believed to be the long-term result. In order to test this hypothesis, subepichondrial surgery was performed in growing dome...

journal_title：Acta oto-laryngologica

authors： Freng A,Haye R

更新日期：1985-09-01 00:00:00

abstract：CONCLUSION:Our numerical simulation model provides an accurate reflection of nasal airflow, and the results were validated by clinical measurements. OBJECTIVES:To evaluate the accuracy of a numerical simulation model of nasal airflow. METHODS:Ten volunteers with normal nasal cavities underwent CT, acoustic rhinometry...

journal_title：Acta oto-laryngologica

authors： Lu J,Han D,Zhang L

更新日期：2014-05-01 00:00:00

abstract：:This study was designed to assess the utility of otolith-ocular reflex testing in patients with complete unilateral peripheral vestibular deficits. Ten subjects were given a clinical vestibular test battery (ENG & vertical rotation) and research oriented tests of otolith function including dynamic posturography with h...

journal_title：Acta oto-laryngologica

authors： Payman RN,Wall C 3rd,Ash-Bernal R

更新日期：1995-11-01 00:00:00

abstract：:Five out of eight consecutive cases with initial symptoms of a 'midline granuloma' were identified as malignant histiocytosis (histiocytic sarcoma) which within 5 months to 4 years led to generalization and death. The three remaining cases also fulfilled the morphological criteria of this type of neoplasia, though the...

journal_title：Acta oto-laryngologica

authors： Laeng H,Gerber H,Mueller J

更新日期：1986-01-01 00:00:00

abstract：:An analysis of auditory brainstem response (ABR) thresholds and ABR-based frequency tuning curves was performed in 15 Sprague-Dawley rats exposed to Haemophilus influenzae type b endotoxin; 5 microg/50 microl toxin was instilled every second day, altogether five times, into the middle ear cavity through a small perfor...

journal_title：Acta oto-laryngologica

authors： Stenqvist M,Anniko M,Pettersson A

更新日期：1997-05-01 00:00:00

abstract：:Intense sound stimulation may result in excessive glutamate release from the inner hair cells, resulting in binding to the postsynaptic glutamate receptors and leading to neuronal degeneration and functional impairment. In this study we investigated the therapeutic effect and time window of caroverine, an N-methyl-D-a...

journal_title：Acta oto-laryngologica

authors： Chen Z,Ulfendahl M,Ruan R,Tan L,Duan M

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...

journal_title：Acta oto-laryngologica

authors： Chelikh L,Teixeira M,Martin C,Sterkers O,Ferrary E,Couloigner V

更新日期：2003-01-01 00:00:00

abstract：:The muscle fiber content of the stapedius muscle of the cat was determined histochemically using a combination of oxidative enzymes and glycolytic markers. The major fiber type present was determined to be the fast oxidative glycolytic type (FOG; 77%). Two other types of fiber were found that could not be placed into ...

journal_title：Acta oto-laryngologica

authors： Lyon MJ,Malmgren LT

更新日期：1982-07-01 00:00:00

abstract：CONCLUSION:In the present study, about one-third of patients with Meniere's disease developed benign paroxysmal positional vertigo (BPPV)-like attacks. Additionally, more than one-third of all vertigo attacks were BPPV-like attacks. Thus, vertigo attacks in patients with Meniere's disease must be carefully treated beca...

journal_title：Acta oto-laryngologica

authors： Taura A,Funabiki K,Ohgita H,Ogino E,Torii H,Matsunaga M,Ito J

更新日期：2014-11-01 00:00:00

abstract：:Several reports indicate that disturbances of the vestibulo-oculomotor ability are a manifestation of the toxic action on the central nervous system exerted by some industrial solvents. The aim of the present investigation was to examine the vestibulo-oculomotor system during exposure to styrene, which is extensively ...

journal_title：Acta oto-laryngologica

authors： Odkvist LM,Larsby B,Tham R,Ahlfeldt H,Andersson B,Eriksson B,Liedgren SR

更新日期：1982-11-01 00:00:00

abstract：:During a one-year period, 82 consecutive patients seeking medical attention for facial palsy primarily of unknown etiology were examined for underlying Ixodes ricinus-borne borreliosis. Evidence of the infection was found in 16 (20%) of the patients, most of whom had cerebrospinal fluid findings indicating meningeal i...

journal_title：Acta oto-laryngologica

authors： Olsson I,Engervall K,Asbrink E,Carlsson-Nordlander B,Hovmark A

更新日期：1988-01-01 00:00:00

abstract：:In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...

journal_title：Acta oto-laryngologica

authors： Yamanobe S,Harris JP,Keithley EM

更新日期：1993-03-01 00:00:00

abstract：:Racial differences in the size, shape and structure of the cranium exist. This paper evaluates the importance of race in influencing the required sizes of craniotomies for gaining access to the lateral end of the internal auditory meatus without breaching the labyrinth via the retrosigmoid approach. Fine-cut CT scans ...

journal_title：Acta oto-laryngologica

authors： Low WK,Fenton JE,Fagan PA,Gibson WP

更新日期：1995-11-01 00:00:00

abstract：CONCLUSION:The external neck brace (ENB) is a new concept in the improvement of peristomal fixation of an automatic stoma valve (ASV), which was evaluated with a new imaging method. The addition of the ENB to the Flexiderm (FLD) and Xtrabase (XB) adhesives significantly reduced absolute mean differences between the spe...

journal_title：Acta oto-laryngologica

authors： Dirven R,Kooijman PG,Maal TJ,Hilgers FJ,Bergé SJ,Marres HA

更新日期：2010-07-01 00:00:00

abstract：:Caloric responses from 50 consecutive patients, referred routinely for investigation of hearing and/or balance problems, were evaluated by computer and manual methods of analysis. Using measures of nystagmic slow-phase velocity, there was found to be a high degree of correlation between the two methods. Of the 50 pati...

journal_title：Acta oto-laryngologica

authors： O'Neill G,Owen WA

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:pH monitoring can reflect the changes in H+ in the airway. OBJECTIVES:To explore the utility of pharyngeal pH monitoring in the diagnosis of laryngopharyngeal reflux disease (LPRD). MATERIAL AND METHODS:Clinical data from 956 suspected LPRD patients from February 2016 to March 2018 were analyzed retrospect...

journal_title：Acta oto-laryngologica

authors： Wang G,Qu C,Wang L,Liu H,Han H,Xu B,Zhou Y,Li B,Zhang Y,Sun Z,Gong J,Li L,Wu W

更新日期：2019-03-01 00:00:00

abstract：:Acoustic rhinometry (AR) evaluates the geometry of the nasal cavity by measuring the minimum cross-sectional area (MCA) and nasal volume (V) by means of acoustic reflection. Understanding the normal and pathologic conditions of the internal nasal cavity using AR is important in the diagnosis of structural abnormalitie...

journal_title：Acta oto-laryngologica

authors： Huang ZL,Wang DY,Zhang PC,Dong F,Yeoh KH

更新日期：2001-10-01 00:00:00

abstract：CONCLUSION:Chances of hearing preservation are better in patients with vestibular schwannoma (VS) from the superior vestibular nerve (SVN) than from the inferior vestibular nerve (IVN). Pathologic posturography and electronystagmography (ENG) findings are more common in schwannomas from the SVN compared with tumors fro...

journal_title：Acta oto-laryngologica

authors： Borgmann H,Lenarz T,Lenarz M

更新日期：2011-05-01 00:00:00

abstract：:Two hundred Malaysian patients representing 227 ears with previously untreated cholesteatoma disease were analysed retrospectively in terms of i) type of disease, i.e. primary acquired attic defect or posterior superior retraction pocket and secondary acquired type cholesteatoma; ii) positive history of previous middl...

journal_title：Acta oto-laryngologica

authors： Lee ST

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:In this paper we test the concept of combining electrical stimulation for high-frequency sound with acoustic hearing for low-frequency information in the same ear. In addition, we test whether residual hearing can be preserved when an electrode is placed up to 10 mm into the inner ear, and whether the site o...

journal_title：Acta oto-laryngologica

authors： Gantz BJ,Turner C

更新日期：2004-05-01 00:00:00

abstract：CONCLUSION:This study demonstrated that treatment with montelukast in combination with levocetirizine may have a beneficial effect on clinical improvement of middle ear fluid in children with otitis media with effusion (OME). OBJECTIVE:To evaluate the effect of the combination of montelukast and levocetirizine on shor...

journal_title：Acta oto-laryngologica

authors： Ertugay CK,Cingi C,Yaz A,San T,Ulusoy S,Erdogmus N,Ertugay OC

更新日期：2013-12-01 00:00:00

abstract：:A method is described for the intravital microscopic observations of rabbit tracheal mucosa microcirculation during compression with a thin, transparent high volume cuff. The cuff pressure (CP) required to cause complete ischemia in the mucosa over the cartilages was measured and a correlation was found to the mean ar...

journal_title：Acta oto-laryngologica

authors： Stenqvist O,Bagge U

更新日期：1979-01-01 00:00:00

abstract：CONCLUSIONS:Our preliminary results indicate that mastoidectomy by reconstruction of the posterior wall and obliteration (MAPRO) avoided the disadvantages of a canal-wall-down mastoidectomy. MAPRO effectively prevented cholesteatoma recurrence, provided an excellent basis for hearing restoration, and was generally wate...

journal_title：Acta oto-laryngologica

authors： Kronenberg J,Shapira Y,Migirov L

更新日期：2012-04-01 00:00:00

abstract：:Electromyographic activity of the vocal muscle was analysed in 10 subjects during the phonation of different vowels and with different voice pitches. Analysis of the firing pattern of single or a few motor units was performed with the aid of an amplitude discriminator on the computer. The firing rate increases with in...

journal_title：Acta oto-laryngologica

authors： Sram F,Syka J

更新日期：1977-07-01 00:00:00

abstract：:An antimicrobial agent, kanamycin, has been shown to produce as an untoward effect, ototoxicity. The purpose of this study was to investigate differential effects of kanamycin ototoxicity as a function of Rx timing with regard to circadian rhythms. Four groups of comparable weight Sprague-Dawley rats received a daily ...

journal_title：Acta oto-laryngologica

authors： Yonovitz A,Fisch JE

更新日期：1991-01-01 00:00:00

abstract：CONCLUSIONS:The risk factors for methicillin-resistant Staphylococcus aureus (MRSA) detection in head and neck cancer patients are the duration of hospitalization, intravenous hyperalimentation, prior antibiotic use, and the coexistence of other pathogens. OBJECTIVES:To shed light on the clinical characteristics of MR...

journal_title：Acta oto-laryngologica

authors： Shiomori T,Miyamoto H,Udaka T,Okochi J,Hiraki N,Hohchi N,Hashida K,Fujimura T,Kitamura T,Nagatani G,Ohbuchi T,Suzuki H

更新日期：2007-02-01 00:00:00

abstract：:Synchronous benign and malignant tumors in the ipsilateral salivary glands are extremely rare. We report a unique case of synchronous unilateral parotid tumors in a 71-year-old man. The main parotid lesion was preoperatively suggested to be adenocarcinoma by fine needle aspiration cytology. A coexisting Warthin's tumo...

journal_title：Acta oto-laryngologica

authors： Roh JL,Kim JM,Park CI

更新日期：2007-01-01 00:00:00

abstract：CONCLUSIONS:The underlying pathophysiological mechanisms of the posterior nasal nerve (PNN) resection involved the suppression of the secretogogue motor and the inhibition of neurogenic inflammation induced by parasympathetic and sensory denervation. OBJECTIVE:The study was designed to clarify the underlying mechanism...

journal_title：Acta oto-laryngologica

authors： Ikeda K,Yokoi H,Saito T,Kawano K,Yao T,Furukawa M

更新日期：2008-01-01 00:00:00