Cuff pressure and microvascular occlusion in the tracheal mucosa. An intravital microscopic study in the rabbit.

Abstract:

:A method is described for the intravital microscopic observations of rabbit tracheal mucosa microcirculation during compression with a thin, transparent high volume cuff. The cuff pressure (CP) required to cause complete ischemia in the mucosa over the cartilages was measured and a correlation was found to the mean arterial blood pressure (MAP). Ischemia was not observed below CP-MAP ratios of 0.40 for untreated animals or below 0.44 for animals where the MAP had been elevated by adrenalin. However, marked reduction of the microvascular blood flow was present at lower CP-MAP ratios, 0.2-0.3, which at a MAP of 75 mmHg corresponds to cuff pressures of 15-20 mmHg. It is therefore advocated that endotracheal cuff pressures are kept below these values to avoid ischemic tissue injury.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Stenqvist O,Bagge U

doi

10.3109/00016487909137192

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

451-4

issue

5-6

eissn

0001-6489

issn

1651-2251

journal_volume

88

pub_type

杂志文章
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    authors: Laciano L,Franke K,Iurato S,Reale E

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  • Meniére's disease. Electron microscopy of the vestibular ganglion and end organs after ultrasound.

    abstract::Material for electron microscopy study was obtained from a patient previously suffering from Meniere's disease and treated by ultrasound. It consisted of parts of the membranous labyrinth as well as the vestibular ganglion. The neuro-epithelium of the macula showed degenerative changes and there was marked vacuolation...

    journal_title:Acta oto-laryngologica

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    更新日期:1975-03-01 00:00:00

  • The relationship between the cytotoxicity of kanamycin and ethacrynic acid for mammalian cells in vitro and their ototoxicity in vivo.

    abstract::Dose-effect curves for inhibition of growth of P388/P mouse lymphoma cells by ethacrynic acid and kanamycin used alone and in combination were determined in vitro. Ethacrynic acid was 600 times more potent than kanamycin and combinations of the drugs resulted in overall additive effects. These results were compared wi...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487909126389

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  • Clinical trial on tinnitus patients with normal to mild hearing loss: broad band noise and mixed pure tones sound therapy.

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  • A Japanese family showing high-frequency hearing loss with KCNQ4 and TECTA mutations.

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  • Laryngeal paraganglioma: an updated critical review.

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,评审

    doi:10.1080/00016480410017576

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  • Is there a deafness duration limit for cochlear implants in post-lingual deaf adults?

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2013.850175

    authors: Moon IS,Park S,Kim HN,Lee WS,Kim SH,Kim JH,Choi JY

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  • Failure of gaze stabilization under high-frequency head oscillation.

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    journal_title:Acta oto-laryngologica

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    doi:10.3109/00016488909127495

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  • Mucin gene expression in nasal polyps.

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    journal_title:Acta oto-laryngologica

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  • Ionic mechanisms sustaining activity in ampullar receptors of the frog.

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    journal_title:Acta oto-laryngologica

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  • Cochlear Implants in Special Cases: Deafness in the Presence of Disabilities and/or Associated Problems.

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    journal_title:Acta oto-laryngologica

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  • Cognitive tinnitus sensitization: behavioral and neurophysiological aspects of tinnitus centralization.

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  • Communication skills in pediatric cochlear implant recipients.

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    pub_type: 杂志文章

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    更新日期:1999-03-01 00:00:00

  • Elevated levels of myelin basic protein in CSF in relation to auditory brainstem responses in Bell's palsy.

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:

    authors: Edström S,Hanner P,Andersen O,Rosenhall U,Vahlne A,Karlsson B

    更新日期:1987-03-01 00:00:00

  • A histochemical characterization of muscle fiber types in the middle ear muscles of the cat. 1. The stapedius muscle.

    abstract::The muscle fiber content of the stapedius muscle of the cat was determined histochemically using a combination of oxidative enzymes and glycolytic markers. The major fiber type present was determined to be the fast oxidative glycolytic type (FOG; 77%). Two other types of fiber were found that could not be placed into ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488209128894

    authors: Lyon MJ,Malmgren LT

    更新日期:1982-07-01 00:00:00

  • Community-acquired methicillin-resistant Staphylococcus aureus infections in discharging ears.

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/0036554021000028076

    authors: Hwang JH,Tsai HY,Liu TC

    更新日期:2002-12-01 00:00:00

  • Hereditary angioneurotic edema of the larynx.

    abstract::Hereditary angioneurotic edema (HAE) is an autosomal dominant disease resulting from a deficiency of functional C1-esterase inhibitor. If not recognized promptly and treated properly the disease can result in a fatal outcome as it causes laryngeal edema, which can lead to a life-threatening acute upper airway obstruct...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

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    更新日期:2005-11-01 00:00:00

  • The impact of comorbidity on the survival of patients with laryngeal squamous cell carcinoma.

    abstract:UNLABELLED:Abstract Conclusions: In survival analysis, the combined Charlson comorbidity index (CCI) can be considered as a prognostic factor independent of the tumor node metastasis (TNM) classification, tumor stage, and tumor location. Severe comorbidity was the factor that had the greatest impact on prognosis in cas...

    journal_title:Acta oto-laryngologica

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    doi:10.3109/00016489.2011.564651

    authors: Gimeno-Hernández J,Iglesias-Moreno MC,Gómez-Serrano M,Carricondo F,Gil-Loyzaga P,Poch-Broto J

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  • Clinical relevance of magnetic resonance imaging and computed tomography in Cogan's syndrome.

    abstract::The Pathologic changes in the inner ears of 5 patients with Cogan's syndrome were studied by a combined application of MR imaging and CT scanning. We used T1- and T2-weighted MR imaging sequences and a special three-dimensional MR imaging technique which allows a very detailed imaging of the inner ear structures. By t...

    journal_title:Acta oto-laryngologica

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    更新日期:1993-09-01 00:00:00

  • The developing electrolytes concentrations of inner ear fluids in guinea pigs.

    abstract::Cochlear endolymph, scala tympani perilymph, and scala vestibuli perilymph were collected from fetal, neonatal, and mature guinea pigs. The concentrations of Na and K in these fluids were then assessed using a microflame photometer. The electrolyte composition in the endolymph was already characterized by a high conce...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488509182256

    authors: Kanoh N,Ohmura M,Fukazawa T,Hirono Y,Makimoto K

    更新日期:1985-05-01 00:00:00

  • Characterization of AMC-HN-9, a cell line established from an undifferentiated carcinoma of the parotid gland: expression of alpha6beta4 with the absence of BP180 and 230.

    abstract::We recently reported the development of a cell line, AMC-HN-9, established from an undifferentiated carcinoma (UDC) of the parotid gland. AMC-HN-9 consists mostly of spindle-shaped cells, has poor in vitro adhesiveness and an in vitro appearance that is different from that of other epithelial cell lines. To test the h...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

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    更新日期:2000-08-01 00:00:00

  • Electrophysiological and biochemical findings in four cases of Meniere's disease.

    abstract::In 4 cases of Meniere's disease, E.P., concentrations of Na, K, Cl, and protein, and osmolality were determined in endolymph from the basal coil of the cochlea. In 3 cases, endolymph was found normal in nature as compared with normal animals. In one long-standing (11 years) case, a strial dysfunction was evidenced. In...

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    pub_type: 杂志文章

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  • Size of the mastoid air cell system obtained with two types of X-ray equipment.

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    pub_type: 杂志文章

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    更新日期:1983-01-01 00:00:00

  • Vestibular dysfunction causing instability in aged patients.

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    pub_type: 杂志文章

    doi:10.3109/00016488709109046

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    更新日期:1987-07-01 00:00:00

  • Inner ear injury caused by air intrusion to the scala vestibuli of the cochlea.

    abstract::In a previous communication, we demonstrated that the introduction of air into the scala tympani of the cochlea causes a decrease of cochlear potentials; however, the change in endocochlear dc potential (EP) was mild and the decreased cochlear microphonics (CM) and compound action potentials (CAP) were, at least parti...

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  • Endolymphatic duct blockage for refractory Ménière's disease: assessment of intraoperative CSF leak on short-term surgical outcomes.

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  • Gene silencing with siRNA targeting E6/E7 as a therapeutic intervention against head and neck cancer-containing HPV16 cell lines.

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