Abstract:
:A method is described for the intravital microscopic observations of rabbit tracheal mucosa microcirculation during compression with a thin, transparent high volume cuff. The cuff pressure (CP) required to cause complete ischemia in the mucosa over the cartilages was measured and a correlation was found to the mean arterial blood pressure (MAP). Ischemia was not observed below CP-MAP ratios of 0.40 for untreated animals or below 0.44 for animals where the MAP had been elevated by adrenalin. However, marked reduction of the microvascular blood flow was present at lower CP-MAP ratios, 0.2-0.3, which at a MAP of 75 mmHg corresponds to cuff pressures of 15-20 mmHg. It is therefore advocated that endotracheal cuff pressures are kept below these values to avoid ischemic tissue injury.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Stenqvist O,Bagge Udoi
10.3109/00016487909137192subject
Has Abstractpub_date
1979-01-01 00:00:00pages
451-4issue
5-6eissn
0001-6489issn
1651-2251journal_volume
88pub_type
杂志文章abstract::The maculae sacculi and utriculi of the chinchilla vestibular labyrinth have been studied by freeze-fracture method. In the replicas extensive zonulae occludentes have been found between sensory and supporting cells at the endolymphatic surface. Gap junctions are located between the supporting cells. Some intramembran...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709128816
更新日期:1977-01-01 00:00:00
abstract::Material for electron microscopy study was obtained from a patient previously suffering from Meniere's disease and treated by ultrasound. It consisted of parts of the membranous labyrinth as well as the vestibular ganglion. The neuro-epithelium of the macula showed degenerative changes and there was marked vacuolation...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509124674
更新日期:1975-03-01 00:00:00
abstract::Dose-effect curves for inhibition of growth of P388/P mouse lymphoma cells by ethacrynic acid and kanamycin used alone and in combination were determined in vitro. Ethacrynic acid was 600 times more potent than kanamycin and combinations of the drugs resulted in overall additive effects. These results were compared wi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126389
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:Tinnitus treatments present a quandary for clinicians, but no thoroughly satisfactory medical treatments are offered to tinnitus patients. OBJECTIVE:We compared sound therapy effects of the broad band noise (BBN) and the mixed pure tones on tinnitus patients with normal to mild hearing loss, and the possibl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016489.2019.1575522
更新日期:2019-03-01 00:00:00
abstract::The DBA/2 strain of mice have genetically induced vestibular dysfunction that presents grossly at an early age as circling behavior and abnormal righting reflexes. The vestibular morphology of this strain has not previously been examined. DBA/2 mice of different ages that showed circling behavior were sacrificed and t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126075
更新日期:1994-07-01 00:00:00
abstract:CONCLUSIONS:We describe a Japanese family with high-frequency sensorineural hearing loss (SNHL) harboring a c.211delC mutation in the KCNQ4 gene. Families showing progressive high-frequency SNHL should be investigated for mutations in the KCNQ4 gene. OBJECTIVE:To determine the responsible deafness gene in a Japanese f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.890740
更新日期:2014-06-01 00:00:00
abstract::Laryngeal paragangliomas are rare submucosal lesions that arise from paraganglion cells located in the false vocal fold and subglottic larynx. To date, 76 recognized cases have been reported in the world literature. Symptoms arise when the lesions become large enough to impair function. Supraglottic paragangliomas cau...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.1080/00016480410017576
更新日期:2004-11-01 00:00:00
abstract:CONCLUSION:Patients with post-lingual deafness should not be excluded from cochlear implantation (CI) on the basis of duration of deafness. We found that the prognosis was favorable in patients who developed deafness after adolescence, even in those with extremely long-term deafness. OBJECTIVES:CI is an effective trea...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.850175
更新日期:2014-02-01 00:00:00
abstract::Gaze functions under high-frequency head oscillations with large amplitudes were investigated in 12 normal subjects. Oscillation amplitude decreased as the frequency increased (31 degrees at 2 Hz to 11 degrees at 5 Hz on average). Maximum head velocity and acceleration were 170-200 degrees/s and 2,500-5,000 degrees/s2...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127495
更新日期:1989-03-01 00:00:00
abstract:CONCLUSIONS:A large set of mucin genes is expressed in nasal polyps. The expression pattern is complex and may reflect the wide spectrum of variables involved in polyp formation and progression. Prospective studies including subgroups of nasal polyps and involving substantial numbers of cases in each subgroup will be r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510027538
更新日期:2005-06-01 00:00:00
abstract::Ionic mechanisms sustaining sensory transduction in crista ampullaris sensory cells have been investigated chiefly by replacing the endolymph with solutions with K+ and Ca++ chelators added. The effects of the modified solutions were evaluated by extracellular and intracellular recordings of both and the presynaptic a...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130893
更新日期:1982-05-01 00:00:00
abstract::The aim of the present study is to construct a reference model with the indication for the attitude, the requirements and the resources needed in order to be able to deal with deafness in the presence of disabilities or associated problems. The study group consisted of 13 adults and 18 children affected by profound de...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/03655230410017193
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:Acquired centralized tinnitus (ACT) is the most frequent type of chronic tinnitus. We introduce a cognitive neurophysiological ACT hypothesis based on centralized cognitive sensitization processes. MATERIAL AND METHODS:Published cognitive sensitization processes were reviewed using PubMed. Furthermore, a Coc...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016333
更新日期:2004-05-01 00:00:00
abstract::Detailed longitudinal studies of speech perception, speech production and language acquisition have justified a significant change in the demographics of congenitally and prelingually deaf children who receive cochlear implants. A trend toward earlier cochlear implantation has been justified by improvements in measure...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950181701
更新日期:1999-03-01 00:00:00
abstract::Myelin basic protein (MBP) in the cerebrospinal fluid (CSF) was quantified from 28 patients with acute facial palsy. The mean value of MBP in CSF in the study group was 3.4 +/- 0.22 micrograms/l (mean +/- SEM), which was significantly higher than the found in 37 healthy subjects (2.4 +/- 0.13 micrograms/l). Using a 95...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::The muscle fiber content of the stapedius muscle of the cat was determined histochemically using a combination of oxidative enzymes and glycolytic markers. The major fiber type present was determined to be the fast oxidative glycolytic type (FOG; 77%). Two other types of fiber were found that could not be placed into ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128894
更新日期:1982-07-01 00:00:00
abstract:OBJECTIVES:Although community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections have recently become an increasing problem in various fields of medicine, they have rarely been studied in the ear. The purpose of this study was to determine the prevalence of community-acquired MRSA infections in disc...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/0036554021000028076
更新日期:2002-12-01 00:00:00
abstract::Hereditary angioneurotic edema (HAE) is an autosomal dominant disease resulting from a deficiency of functional C1-esterase inhibitor. If not recognized promptly and treated properly the disease can result in a fatal outcome as it causes laryngeal edema, which can lead to a life-threatening acute upper airway obstruct...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510038185
更新日期:2005-11-01 00:00:00
abstract:UNLABELLED:Abstract Conclusions: In survival analysis, the combined Charlson comorbidity index (CCI) can be considered as a prognostic factor independent of the tumor node metastasis (TNM) classification, tumor stage, and tumor location. Severe comorbidity was the factor that had the greatest impact on prognosis in cas...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.564651
更新日期:2011-08-01 00:00:00
abstract::The Pathologic changes in the inner ears of 5 patients with Cogan's syndrome were studied by a combined application of MR imaging and CT scanning. We used T1- and T2-weighted MR imaging sequences and a special three-dimensional MR imaging technique which allows a very detailed imaging of the inner ear structures. By t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135875
更新日期:1993-09-01 00:00:00
abstract::Cochlear endolymph, scala tympani perilymph, and scala vestibuli perilymph were collected from fetal, neonatal, and mature guinea pigs. The concentrations of Na and K in these fluids were then assessed using a microflame photometer. The electrolyte composition in the endolymph was already characterized by a high conce...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509182256
更新日期:1985-05-01 00:00:00
abstract::We recently reported the development of a cell line, AMC-HN-9, established from an undifferentiated carcinoma (UDC) of the parotid gland. AMC-HN-9 consists mostly of spindle-shaped cells, has poor in vitro adhesiveness and an in vitro appearance that is different from that of other epithelial cell lines. To test the h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000513
更新日期:2000-08-01 00:00:00
abstract::In 4 cases of Meniere's disease, E.P., concentrations of Na, K, Cl, and protein, and osmolality were determined in endolymph from the basal coil of the cochlea. In 3 cases, endolymph was found normal in nature as compared with normal animals. In one long-standing (11 years) case, a strial dysfunction was evidenced. In...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409132935
更新日期:1984-05-01 00:00:00
abstract::The first systematically performed study concerning the size variation of the mastoid air cell system was measured on the X-ray film in a lateral projection, as exposed on the skull table. A new type of equipment (Orbix) with an isocentric motion of the roentgen tube and the film cassette and a different magnification...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309130921
更新日期:1983-01-01 00:00:00
abstract::Unilateral vestibular hypofunction (UVH) is a common vestibular dysfunction. Its influence upon the vestibulospinal reflex (VSR) is studied by posturography. The postural sway is disturbed when the VSR is disregulated because of the UVH. The degree of disturbance depends on the effectivity of the central compensation....
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709109046
更新日期:1987-07-01 00:00:00
abstract::In a previous communication, we demonstrated that the introduction of air into the scala tympani of the cochlea causes a decrease of cochlear potentials; however, the change in endocochlear dc potential (EP) was mild and the decreased cochlear microphonics (CM) and compound action potentials (CAP) were, at least parti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135892
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:Endolymphatic sac decompression has shown limited success for the treatment of Ménière's disease (MD). We have published a novel technique with very promising results for the treatment of refractory MD: the Endolymphatic Duct Blockage (EDB) with two titanium clips. One of the challenges of this technique was...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1481524
更新日期:2018-10-01 00:00:00
abstract::Acute and late phase (dual) symptomatic responses after allergen challenge commonly occur in allergic asthma. The aim of the present study was to explore the occurrence of allergen challenge-induced biphasic responses in patients with chronic perennial allergic rhinitis living in an area with high house dust mite (HDM...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300102950
更新日期:2001-04-01 00:00:00
abstract:CONCLUSION:Our results indicate that siRNA E6 and/or E7 may have potential as a gene-specific therapy for human papillomavirus (HPV) type 16 (HPV16)-related squamous cell carcinoma of the head and neck (HNSCC). OBJECTIVES:To evaluate the effectiveness of siRNA targeting E6 and/or E7 on the in vitro and in vivo growth ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.773405
更新日期:2013-07-01 00:00:00
abstract::The present paper investigates the hearing function in chronic otitis media vs. tympanoplasty in 41 patients with bilateral chronic otitis media, operated on unilaterally. The auditory evaluation was performed immediately before surgery and at a follow-up time varying from 1 to 14 years (mean = 5 years). Results were ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138410
更新日期:1991-01-01 00:00:00