Abstract:
:An analysis of auditory brainstem response (ABR) thresholds and ABR-based frequency tuning curves was performed in 15 Sprague-Dawley rats exposed to Haemophilus influenzae type b endotoxin; 5 microg/50 microl toxin was instilled every second day, altogether five times, into the middle ear cavity through a small perforation in the tympanic membrane. ABR was measured 48 h after the second application and 24 h, 48 h, 5 days and 10 days after the fifth instillation. Five applications of toxin had no statistical effect on ABR thresholds and no changes in TC configuration were observed. It is concluded that Haemophilus influenzae type b endotoxin, instilled repeatedly through the tympanic membrane into the middle ear, does not affect cochlear electrophysiology.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Stenqvist M,Anniko M,Pettersson Adoi
10.3109/00016489709113406subject
Has Abstractpub_date
1997-05-01 00:00:00pages
352-7issue
3eissn
0001-6489issn
1651-2251journal_volume
117pub_type
杂志文章abstract:BACKGROUND:Differential diagnosis of persistent vertigo/dizziness in patients with a past history of vestibular neuritis (VN) and sudden deafness with vertigo (SDV) could sometimes be difficult for physicians due to variable vertiginous symptoms from rotatory to floating sensation. OBJECTIVES:The main purpose of the p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1813327
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Endolymphatic sac decompression has shown limited success for the treatment of Ménière's disease (MD). We have published a novel technique with very promising results for the treatment of refractory MD: the Endolymphatic Duct Blockage (EDB) with two titanium clips. One of the challenges of this technique was...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1481524
更新日期:2018-10-01 00:00:00
abstract:CONCLUSIONS:Intra-arterial high-dose cisplatin chemoradiation (CRT-IA) with sodium thiosulfate (STS) causes relatively less severe cisplatin ototoxicity than intravenous cisplatin chemoradiation without STS (CRT-IV). The results of this study also suggest that early detection of ototoxicity is possible by testing the h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1035797
更新日期:2015-09-01 00:00:00
abstract::Evaluation of some 200 endolymph proteins indicates that they are predominantly derived from plasma. However, the profile of endolymph proteins is remarkably similar to that of perilymph and entirely different from that of plasma. This supports the current consensus that perilymph rather than plasma is the (direct) so...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.1080/00016489950181260
更新日期:1999-01-01 00:00:00
abstract::It is well documented that quinine induces reversible hearing loss and tinnitus. The purpose in this study was to induce a quinine hearing loss and to investigate if verapamil, a Ca2+ channel antagonist of L-type might affect the response. Pigmented guinea pigs (n = 24) were anaesthetized by atropine. Hypnorm and mida...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709117990
更新日期:1997-01-01 00:00:00
abstract::Eight patients with dystrophia myotonica (Steinert) were studied. They all had myotonia and pathological EMG and in some cases other signs of the disease. The 50% relaxation times of the stapedius reflex were significantly prolonged compared with a control group of 40 healthy, young subjects with normal hearing and no...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128937
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the capability of indirect computed tomography and magnetic resonance lymphography (CT/MR-LG) with gadolinium-loaded, polyethylenimine-entrapped gold nanoprobes (Gd-Au PENPs) for assessing lingual sentinel lymph node (SLN) metastasis in a tongue VX2 carcinoma model. MATERIALS AND METHODS:Seventee...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1441544
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To investigate the hearing prognosis of idiopathic sudden sensorineural hearing loss (SSNHL) treated with different initial therapies. METHODS:Subjects consisted of patients diagnosed with idiopathic SSNHL within 7 days from onset and showing severe hearing loss (≥60 dB), who were registered in a Japanese mu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2017.1296970
更新日期:2017-01-01 00:00:00
abstract::Reserpine (2 mg/kg and 10 mg/kg, i.p.), an adrenergic blocker, was administered to normal guinea pigs, and samples of serum, CSF, scala tympani perilymph, scala vestibuli perilymph and cochlear endolymph were collected. The concentrations of Na and K in these fluids were then assessed to observe electrolyte distributi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107540
更新日期:1984-07-01 00:00:00
abstract::The muscle fiber content of the stapedius muscle of the cat was determined histochemically using a combination of oxidative enzymes and glycolytic markers. The major fiber type present was determined to be the fast oxidative glycolytic type (FOG; 77%). Two other types of fiber were found that could not be placed into ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128894
更新日期:1982-07-01 00:00:00
abstract:CONCLUSION:Reconstruction with a vascularized bone flap provided superior postoperative outcomes compared with reconstruction with a soft tissue free flap. However, patients obtained acceptable long-term functional outcomes even with a soft tissue free flap and this method is an option in selected patients. A multidisc...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.824111
更新日期:2013-12-01 00:00:00
abstract::A questionnaire was devised to quantify and measure four categories: the behavioral characteristics of Type A, self-restraint and escape; the causes of anxiety; means of relaxation; and symptoms incidental to anxiety. Questionnaire analysis was performed in patients (n = 60) with Meniere's disease and in a control pop...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300043721
更新日期:2001-01-01 00:00:00
abstract::Nitric oxide synthase (NOS) isoforms I and III were localized in the guinea pig cochlea by indirect immunohistochemistry using frozen sections and paraffin sections. NOS I staining was observed in the cytoplasm of outer hair cells, in nerve cell somata and fibers of the spiral ganglion, and in axonal profiles of the s...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137914
更新日期:1996-09-01 00:00:00
abstract:CONCLUSION:The age-related changes in ocular vestibular-evoked myogenic potentials (oVEMPs) elicited by galvanic vestibular stimulation (GVS) and bone-conducted vibration (BCV) might be attributed to the morphological degeneration of the vestibular system. OBJECTIVE:This study employed GVS and BCV modes for eliciting ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.708437
更新日期:2012-12-01 00:00:00
abstract::Based on the late results of tympanoplasty on 300 ears and of one-stage mastoidectomy and tympanoplasty on 269 discharging ears, the problems involved in staging tympanoplasty are discussed. The results of one-stage operations were found to be satisfactory 2-10 years after operation. The frequency of recurrent cholest...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609120906
更新日期:1976-09-01 00:00:00
abstract::We examined the mucosa of 50 rat middle ears in an experimental model of acute otitis media, in order to obtain information on the mechanisms of polyp formation. The right middle ear of 25 rats was inoculated with type 3 pneumococci, and the left ear served as a control. The animals were killed, the middle ear bulla r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509133351
更新日期:1995-01-01 00:00:00
abstract::The early development of human otoconial membranes was studied by scanning electron microscopy and X-ray microanalysis; 87 specimens, ranging from 7 to 12 weeks gestational age were examined. A few otoconia, which contained calcium, were present in the utricle by the end of the seventh week. By 8 weeks, both the saccu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128884
更新日期:1982-07-01 00:00:00
abstract::Efforts to evaluate findings in the nystagmogram were made in a material of 338 vertiginous and dizzy patients. A spontaneous nystagmus, a positional nystagmus as well as a difference in caloric reactivity are as solitary findings of lettle value for revealing peripheral disorders. On the other hand, central disturban...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809124728
更新日期:1978-07-01 00:00:00
abstract::The gas nitric oxide (NO) is present in high concentrations in human nasal airways. Since NO is known to inhibit the growth of bacteria and viruses, it has been suggested that airborne NO represents the first line of defence against pathogens in the upper airways. Low nasal NO levels have been reported previously in p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000676
更新日期:2000-03-01 00:00:00
abstract:CONCLUSION:It is thought that oxidative stress may be the major cause of the increase in the oxide thiol form in the study group. The relationship between oxidative stress status and dynamic thiol/disulphide in nasal polyposis now needs to be investigated. OBJECTIVES:The purpose of this study was to evaluate the relat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1186833
更新日期:2016-11-01 00:00:00
abstract::The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Tr...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489.2010.541941
更新日期:2011-06-01 00:00:00
abstract::Primary afferent projections from singular parts of the vestibular labyrinth were studied in the guinea pig. The posterior ampullary nerve, the common trunk of the anterior and lateral ampullary nerves, as well as fibers innervating the macula sacculi or the macula utriculi were traced with crystals of horseradish per...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137430
更新日期:1992-01-01 00:00:00
abstract:CONCLUSION:We demonstrated an early increase in aquaporin 2 (AQP2) expression in a motor nerve (extratemporal facial nerve, FN) following acute peripheral compression (crush), concomitant to effective development of motor dysfunction (facial palsy). The early increase in AQP2 expression that occurred concomitantly with...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1010104
更新日期:2015-07-01 00:00:00
abstract::The gram negative bacteria, nontypable Haemophilus influenzae (NTHi) was used to induce otitis media in a total of 18 chinchillas. Three days post-inoculation, three cohorts of 6 chinchillas each were treated daily for four days with either ceftriaxone, chloramphenicol, or diluent without antibiotics. Middle ear fluid...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709118000
更新日期:1997-01-01 00:00:00
abstract:CONCLUSION:The Na-K-2Cl cotransporter-1 (NKCCl) may be essential for the maintenance and functioning of the vestibular morphology in mice and it is strongly expressed in human vestibular end organs. OBJECTIVE:NKCCl is a member of the cation-coupled chloride transporter which participates in salt transport and cell vol...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510012309
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Traumatic tympanic membrane perforation (TTMP) is usually managed conservatively because most close spontaneously within a few months. Nevertheless, spontaneous closure of TTMP during long-term observation has not been well described in the literature. OBJECTIVES:The present study investigated factors assoc...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1592225
更新日期:2019-06-01 00:00:00
abstract::Background: The treatments of horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV) have low remission rates ranging between 60% and 90%, connected to the difficulty in correctly identifying the affected side of HSC-BPPV. Objective: To propose and compare the efficacy of the latency test (LT) i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1635712
更新日期:2019-10-01 00:00:00
abstract::Normal quantum type bone remodeling was studied in temporal bones of young domestic pigs by means of combined microradiography, osteofluorochrome labelling and osteoid staining. Evolving secondary osteons were morphologically normal although much less in the otic capsule than in the surrounding compacta of the tempora...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009122540
更新日期:1990-09-01 00:00:00
abstract::In electrocochleography (ECochG) compound action potential (CAP) and summation potential (SP) are usually separated from the cochlear microphonic (CM) by the CM cancellation technique consisting in averaging the responses evoked by rarefaction and condensation clicks. With the aim of analysing the ECochG responses evo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000892
更新日期:2000-03-01 00:00:00
abstract::Gaze functions under high-frequency head oscillations with large amplitudes were investigated in 12 normal subjects. Oscillation amplitude decreased as the frequency increased (31 degrees at 2 Hz to 11 degrees at 5 Hz on average). Maximum head velocity and acceleration were 170-200 degrees/s and 2,500-5,000 degrees/s2...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127495
更新日期:1989-03-01 00:00:00