Abstract:
CONCLUSION:It is thought that oxidative stress may be the major cause of the increase in the oxide thiol form in the study group. The relationship between oxidative stress status and dynamic thiol/disulphide in nasal polyposis now needs to be investigated. OBJECTIVES:The purpose of this study was to evaluate the relation between nasal polyposis and thiol/disulphide homeostasis, used as a marker of oxidative stress, by measuring that exchange using a novel technique. MATERIALS AND METHODS:The study group consisted of 40 patients (mean age = 46.75 ± 13.92 years) with bilateral nasal polyposis patients admitted to the hospital. The control group consisted of 31 (mean age = 43.20 ± 5.68 years) age, sex, and body mass index matched healthy subjects. Thiol/disulphide homeostasis concentrations were measured using a newly-developed method (Erel & Neselioglu). RESULTS:Native thiol and total thiol levels were lower in the study group compared to the control group (native thiol = 415.8 ± 69.1 μmol/L vs 448.7 ± 37.5 μmol/L, p < 0.05; total thiol = 449.02 ± 72.0 μmol/L vs 477.28 ± 44.5 μmol/L, p < 0.05, respectively). Disulphide level and the disulphide/native thiol and disulphide/total thiol ratios were higher in the study group compared to the control group (disulphide = 16.58 ± 5.04 μmol/L vs 14.28 ± 5.3 μmol/L, p < 0.05; disulphide/native thiol ratio = 4.07 ± 1.52% vs 3.14 ± 1.04%, p < 0.05, disulphide/total thiol ratio = 3.73 ± 1.23% vs 2.94 ± 0.92%, p < 0.05, respectively).
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Şimşek E,Erel O,Bicer CK,Çarlıoğlu Adoi
10.1080/00016489.2016.1186833subject
Has Abstractpub_date
2016-11-01 00:00:00pages
1180-1183issue
11eissn
0001-6489issn
1651-2251journal_volume
136pub_type
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journal_title:Acta oto-laryngologica
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doi:10.3109/00016489.2014.971464
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doi:10.1080/00016480701362002
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doi:10.1080/00016480701230936
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abstract:CONCLUSIONS:The incidence rate of hypothyroidism after treatment for laryngeal and hypopharyngeal cancer is high, especially after combination treatment. An association between hypothyroidism and autoantibodies was found. OBJECTIVES:The incidences of hypothyroidism and autoantibodies were assessed retrospectively in 1...
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doi:10.1080/00016480600818096
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abstract::Background: The treatments of horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV) have low remission rates ranging between 60% and 90%, connected to the difficulty in correctly identifying the affected side of HSC-BPPV. Objective: To propose and compare the efficacy of the latency test (LT) i...
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doi:10.1080/00016480260000120
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doi:10.1080/00016480701200350
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更新日期:2018-02-01 00:00:00
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doi:10.1080/00016480500395757
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