MASPIN tumour-suppressing activity in head and neck squamous cell carcinoma: emerging evidence and therapeutic perspectives.

abstract：OBJECTIVES:Hearing loss after spinal anesthesia has been reported to be related to the transmission of a reduced subarachnoid pressure to the inner ear via the cochlear aqueduct due to loss of spinal fluid. However, there are also some controversies related to this phenomenon, which require systematic investigation. M...

journal_title：Acta oto-laryngologica

authors： Cosar A,Yetiser S,Sizlan A,Yanarates O,Yildirim A

更新日期：2004-12-01 00:00:00

abstract：:The vascular pattern of the rat cochlea was demonstrated by the aid of Berlin Blue (Prussian Blue) contrast. The vascular anatomy is similar to other mammals. The infrequent occurrence of the vessel of the basilar membrane under the organ of Corti is interesting in respect to its presumed importance for the oxygen sup...

journal_title：Acta oto-laryngologica

authors： Hornstrand C,Axelsson A,Vertes D

更新日期：1980-01-01 00:00:00

abstract：CONCLUSION:Our results suggest that patients with migraine or tension-type headache have subclinical deviations of the subjective visual vertical, which may be associated with their subjective imbalance. OBJECTIVES:Patients affected by migraine or tension-type headache often complain of unsteadiness. However, they rar...

journal_title：Acta oto-laryngologica

authors： Asai M,Aoki M,Hayashi H,Yamada N,Mizuta K,Ito Y

更新日期：2009-01-01 00:00:00

abstract：CONCLUSION:Mouse embryonic stem cells (ESCs) transplanted into the scala tympani are able to migrate in the cochlea of rats deafened with aminoglycoside and partly restore the structure of sensory epithelia of the inner ear. OBJECTIVES:To explore the migration and differentiation of enhanced green fluorescence protein...

journal_title：Acta oto-laryngologica

authors： Zhao LD,Li L,Wu N,Li DK,Ren LL,Guo WW,Sun JH,Liu HZ,Chen ZT,Xing GQ,Yang SM

更新日期：2013-02-01 00:00:00

abstract：:Background: Recurrent respiratory papillomatosis (RRP) remains a challenging and frustrating disease to treat.Objective: To explore the efficacy of microsurgery in combined with Topical-PDT in treating recurrent respiratory papillomatosis.Materials and methods: Fifty patients with RRP were treated with microsurgery in...

journal_title：Acta oto-laryngologica

authors： Yang S,Zhou C,Sun B,Wang F,Han Z,Zhang H,Han J,Shen Y,Zhang J

更新日期：2019-12-01 00:00:00

abstract：CONCLUSION:The chewing gum indirectly affects postural control by influencing vestibular function to stabilize posture during upright standing. OBJECTIVES:This study aimed to evaluate the effect of chewing gum on static posturography in patients. METHODS:The subjects were 26 patients with chronic balance disorders. T...

journal_title：Acta oto-laryngologica

authors： Goto F,Kushiro K,Tsutsumi T

更新日期：2011-11-01 00:00:00

abstract：:The trachea whole organ perfusion technique was used to study the effect of tumor necrosis factor alpha (TNF alpha) and interleukin-1 alpha (IL-1 alpha) on the adherence of otitis media pathogen Streptococcus pneumoniae (Spn) type 6A. Tracheas were removed from chinchillas and divided equally. One-half trachea was act...

journal_title：Acta oto-laryngologica

authors： Tong HH,Fisher LM,Kosunick GM,Demaria TF

更新日期：1999-01-01 00:00:00

abstract：:The aerobic and anaerobic bacterial flora of middle ear exudate (MEE) of 47 consecutive patients with chronic suppurative otitis media were studied using a quantitative bacteriological technique under strictly anaerobic conditions. Specimens from the external auditory canal (EAC) and the nasopharynx (NP) were obtained...

journal_title：Acta oto-laryngologica

authors： Jonsson L,Schwan A,Thomander L,Fabian P

更新日期：1986-11-01 00:00:00

abstract：:The goal of this investigation was to develop a method of surgical removal of the semicircular canals of the rabbit without induction of auditory impairment. Four different surgical techniques were utilized: i) fenestration of the lateral semicircular canal; ii) fibrin glue perfusion of the canal following fenestratio...

journal_title：Acta oto-laryngologica

authors： Gjuric M,Wigand ME,Hosemann W

更新日期：1992-11-01 00:00:00

abstract：CONCLUSION:Chronic subjective dizziness (CSD) is frequent and affects twice as many women as men. Anxiety is a strong predisposing factor. The pathophysiologic concept of this disorder assumes that balance function and emotion share common neurologic pathways, which might explain that the balance disorder can provoke f...

journal_title：Acta oto-laryngologica

authors： Odman M,Maire R

更新日期：2008-10-01 00:00:00

abstract：:An antimicrobial agent, kanamycin, has been shown to produce as an untoward effect, ototoxicity. The purpose of this study was to investigate differential effects of kanamycin ototoxicity as a function of Rx timing with regard to circadian rhythms. Four groups of comparable weight Sprague-Dawley rats received a daily ...

journal_title：Acta oto-laryngologica

authors： Yonovitz A,Fisch JE

更新日期：1991-01-01 00:00:00

abstract：CONCLUSIONS:A large set of mucin genes is expressed in nasal polyps. The expression pattern is complex and may reflect the wide spectrum of variables involved in polyp formation and progression. Prospective studies including subgroups of nasal polyps and involving substantial numbers of cases in each subgroup will be r...

journal_title：Acta oto-laryngologica

authors： Ali MS,Wilson JA,Bennett M,Pearson JP

更新日期：2005-06-01 00:00:00

abstract：:Cochlear endolymph, scala tympani perilymph, and scala vestibuli perilymph were collected from fetal, neonatal, and mature guinea pigs. The concentrations of Na and K in these fluids were then assessed using a microflame photometer. The electrolyte composition in the endolymph was already characterized by a high conce...

journal_title：Acta oto-laryngologica

authors： Kanoh N,Ohmura M,Fukazawa T,Hirono Y,Makimoto K

更新日期：1985-05-01 00:00:00

abstract：:Cell proliferation in the endolymphatic sac (ES) after immunostimulation was assessed immunohistochemically. Guinea pigs were employed as experimental animals and keyhole limpet hemocyanin was used as the antigen. After i.p. injection of 5-bromo-2'-deoxyuridine (BrdUrd), the BrdUrd+ cells were counted to assess the nu...

journal_title：Acta oto-laryngologica

authors： Takahashi M,Tomiyama S

更新日期：1995-05-01 00:00:00

abstract：:Background: Odontogenic sinusitis (OS) is a common but underdiagnosed form of acute rhinosinusitis (ARS). OS carries no specific characteristics, but unilateral symptoms and certain microbiological as well as radiological findings indicate odontogenic origin. Aims/objectives: We studied the proportion of OS in ARS pat...

journal_title：Acta oto-laryngologica

authors： Wuokko-Landén A,Blomgren K,Välimaa H

更新日期：2019-09-01 00:00:00

abstract：CONCLUSIONS:The present study revealed that miR-21 promotes the proliferation and invasion of cholesteatoma keratinocytes. These results provide a partial explanation for the more aggressive clinical behavior observed in cholesteatoma. OBJECTIVE:This study aims to investigate the post-transcriptional regulatory effect...

journal_title：Acta oto-laryngologica

authors： Chen X,Li X,Qin Z

更新日期：2016-12-01 00:00:00

abstract：CONCLUSION:The amendments made to pre-existing transcanal approaches limit the possibility of extrusion of the electrode and reduce the time of 'blind' surgery. OBJECTIVE:Alternative techniques to classic mastoidectomy and posterior tympanotomy for cochlear implantation have already been described but their main drawb...

journal_title：Acta oto-laryngologica

authors： Guevara N,Bailleux S,Santini J,Castillo L,Gahide I

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The role of endonasal endoscopic surgery and radiotherapy in the treatment of skull base chordomas remains unclear. OBJECTIVE:We investigated the effect of endonasal endoscopic surgery and radiotherapy as treatment for skull base chordomas. METHOD:We investigated 46 patients (2006-2018) treated at the Affi...

journal_title：Acta oto-laryngologica

authors： Li H,Zhang H,Hu L,Wang H,Wang D

更新日期：2020-09-01 00:00:00

abstract：CONCLUSION:In patients with early glottic squamous cell carcinoma (SCC) submitted to CO2 laser endoscopic resection, local disease recurrence was significantly correlated with the presence of positive additional surgical margins on permanent sections. OBJECTIVES:To evaluate the rate of cancer recurrence in patients wi...

journal_title：Acta oto-laryngologica

authors： Crespo AN,Chone CT,Gripp FM,Spina AL,Altemani A

更新日期：2006-03-01 00:00:00

abstract：:Detection of immune complexes (ICs) of IgG, IgM, or IgA isotypes in middle ear effusions (MEEs) by the solid-phase anti-C3 ELISA and cytologic analyses of MEEs were done in 245 patients with otitis media with effusion (OME). In 320 ears, the clinical classification was acute, 10.3%; subacute, 16.6%; chronic, 73.1%. In...

journal_title：Acta oto-laryngologica

authors： Yamanaka N,Somekawa Y,Suzuki T,Kataura A

更新日期：1987-11-01 00:00:00

abstract：:Primary non-Hodgkin's lymphoma of the nasal cavity is a disease more likely to affect men than women; it is characterized by a T cell immunophenotype and is often associated with involvement of the paranasal structures and with high recurrence rates. Many authors report that its extremely poor prognosis depends on tum...

journal_title：Acta oto-laryngologica

authors： Cavalot AL,Ricci E,Nazionale G,Palonta F,Fadda GL

更新日期：2000-06-01 00:00:00

abstract：CONCLUSION:The average recovery of hearing and cessation of tinnitus was significantly better after treatment with Radix Astragali (RA) than after non-treatment with RA. RA can be valuable adjuvant therapy for patients with acute acoustic trauma (AAT). OBJECTIVES:AAT is one of the early indications for the use of RA. ...

journal_title：Acta oto-laryngologica

authors： Xiong M,He Q,Lai H,Huang W,Wang L,Yang C,Wang J

更新日期：2011-10-01 00:00:00

abstract：CONCLUSION:Intra-tympanic dexamethasone injection (ITD) could serve as a first-line intra-tympanic (IT) treatment for Meniere's disease (MD), regardless of hearing level. Even if the response to initial ITD course was unsatisfactory, a repeated course may be beneficial with some patients. OBJECTIVES:This study examine...

journal_title：Acta oto-laryngologica

authors： Leng Y,Liu B,Zhou R,Liu J,Liu D,Zhang SL,Kong WJ

更新日期：2017-02-01 00:00:00

abstract：CONCLUSION:Cochleostomy is the most efficient approach in delivering PEG-b-PCL polymersomes (PMs) to the inner ear. PMs can be delivered to the vestibule by transtympanic injection or cochleostomy. OBJECTIVE:To evaluate the efficiency of delivering PEG-b-PCL PMs into the inner ear using different approaches. METHODS:...

journal_title：Acta oto-laryngologica

authors： Zhang Y,Zhang W,Johnston AH,Newman TA,Pyykk I,Zou J

更新日期：2011-12-01 00:00:00

abstract：:By a careful ENT and oral examination of 111 patients with suspected chronic maxillary sinusitis, the diagnosis was verified in only 56% (62/111). In 29 of these 62 patients (47%) a relation to dental infections was found, periodontitis being as frequent as apical granulomas. In 61% of the patients, in whom the diagn...

journal_title：Acta oto-laryngologica

authors： Lindahl L,Melén I,Ekedahl C,Holm SE

更新日期：1982-01-01 00:00:00

abstract：:Retropharyngeal haematomas (RPHs) are rare but potentially life-threatening conditions that require a prompt diagnosis. However, the clinical scenario is not always straightforward as their presentation may be insidious, with no specific signs or symptoms. Treatment of RPH is conservative in the majority of cases, wit...

journal_title：Acta oto-laryngologica

authors： Chiti-Batelli S,Vaz F,Coman S

更新日期：2005-04-01 00:00:00

abstract：CONCLUSION:Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study. Resectability of the tumor seems to be major prognostic factor of temporal bone SCC. OBJECTIVE:Prognostic f...

journal_title：Acta oto-laryngologica

authors： Ito M,Hatano M,Yoshizaki T

更新日期：2009-11-01 00:00:00

abstract：:Otorrhea of leaked cerebrospinal fluid and meningitis in a 33-year-old male originated from an encephalic herniation into the middle ear following traumatic temporal bone fracture. CT demonstrated a mixed-type fracture consisting of a longitudinal fracture and a posterior oblique fracture of the left temporal bone. Th...

journal_title：Acta oto-laryngologica

authors： Nishiike S,Miyao Y,Gouda S,Shimada N,Nagai M,Nakagawa A,Konishi M,Sakata Y

更新日期：2005-08-01 00:00:00

abstract：:Serum type (IgG, IgM and IgA-class) and secretory type antibodies specific to Streptococcus pneumoniae (Pn), Haemophilus influenzae (Hi) and Branhamella catarrhalis (Br) were measured by enzyme-linked immunosorbent assay (ELISA) in 46 serum and 114 middle ear effusion (MEE) samples from 85 children with acute otitis m...

journal_title：Acta oto-laryngologica

authors： Karjalainen H,Koskela M,Luotonen J,Herva E,Sipilä P

更新日期：1990-01-01 00:00:00

abstract：:We previously reported that long-term exposure to glutamate (Glu) induced death of cochlear outer hair cells (OHCs). However, the mechanisms of OHC death induced by Glu were unclear. In the central nervous system, Glu is known to interfere with a cystine-Glu antiporter, leading to a decrease in cystine uptake and redu...

journal_title：Acta oto-laryngologica

authors： Sunami K,Yamane H,Takayama M,Nakagawa T,Konishi K,Iguchi H

更新日期：1999-01-01 00:00:00