Comparison of the distribution pattern of PEG-b-PCL polymersomes delivered into the rat inner ear via different methods.

abstract：:Three hundred and fifty-four patients with squamous cell carcinoma of the oral cavity, oropharynx, supraglottic larynx, hypopharynx or maxillary sinus have been randomized for preoperative radiation therapy and surgery versus surgery and postoperative radiation therapy plus, in the case of patients with lesions of the...

journal_title：Acta oto-laryngologica

authors： Snow JB,Gelber RD,Kramer S,Davis LW,Marcial VA,Lowry LD

更新日期：1981-05-01 00:00:00

abstract：CONCLUSION:It is thought that oxidative stress may be the major cause of the increase in the oxide thiol form in the study group. The relationship between oxidative stress status and dynamic thiol/disulphide in nasal polyposis now needs to be investigated. OBJECTIVES:The purpose of this study was to evaluate the relat...

journal_title：Acta oto-laryngologica

authors： Şimşek E,Erel O,Bicer CK,Çarlıoğlu A

更新日期：2016-11-01 00:00:00

abstract：:An oral dose of 400 mg enoxacin was given to each of 19 patients with long-standing secretory otitis media (SOM). A total of 27 samples of middle ear effusion (MEE) and blood were collected at different intervals during a 6-h period after administration of the drug. The concentration of enoxacin in MEE and serum was d...

journal_title：Acta oto-laryngologica

authors： Sundberg L,Edén T

更新日期：1990-05-01 00:00:00

abstract：:This work describes the different patterns of expression of integrins and extracellular matrix proteins in normal and transformed mucosa in laryngeal and oropharyngeal carcinomas. Samples from each tumor group were sectioned and examined by immunohistochemistry using monoclonal antibodies raised against integrin chain...

journal_title：Acta oto-laryngologica

authors： Ricci E,Cavalot AL,Sanvito F,Bussi M,Albera R,Staffieri A,Cortesina G,Marchisio PC

更新日期：2002-03-01 00:00:00

abstract：:Enzymatic tracer techniques to study normal and pathologic strial capillary transport pose various problems. The use of electron opaque tracers can circumvent many of these problems. Iron dextran (mol. diam 20--70 A) and ferritin (mol. diam 110 A) were injected intravenously and the mice sacrificed at intervals of 1/2...

journal_title：Acta oto-laryngologica

authors： Santos-Sacchi J,Marovitz WF

更新日期：1980-01-01 00:00:00

abstract：:Vascularization between vestibular schwannomas and the adjacent eighth cranial nerve was examined in order to elucidate the angiogenic effect of these tumours. Specimens from 12 patients were examined by light microscopy and immunohistochemistry (series 1), while specimens from another 17 patients were examined by lig...

journal_title：Acta oto-laryngologica

authors： Matsunaga T,Kanzaki J,Hosoda Y

更新日期：1996-01-01 00:00:00

abstract：:Total laryngectomy for laryngeal squamous cell carcinoma means a drastic change in the way of living for a patient. New surgical techniques such as laser surgery attempt to save the voice. To be oncologically correct, an accurate assessment of the tumor extent is necessary. Imaging is especially important in determini...

journal_title：Acta oto-laryngologica

authors： Declercq A,Van den Hauwe L,Van Marck E,Van de Heyning PH,Spanoghe M,De Schepper AM

更新日期：1998-11-01 00:00:00

abstract：:Synthesis of prostaglandins (PGs) was characterized in the lateral wall (LW) of guinea-pig cochlea. Basal synthesis at 37 degrees C was about 480 pg/LW (12.8 ng X mg-1 protein) for PGI2 and 85 pg/LW (2.3 ng X mg-1 protein) for PGE2, levelling out after 10 min of incubation. Incubation with arachidonic acid (10(-5) M) ...

journal_title：Acta oto-laryngologica

authors： Tran Ba Huy P,Ferrary E,Escoubet B,Sterkers O

更新日期：1987-05-01 00:00:00

abstract：CONCLUSION:The improved biocompatibility of Bioverit II coated with a nanostructured surface shows promising qualities for use in human reconstructive middle ear surgery. In the case of chitosan-hydroxyapatite composite prostheses, further investigations regarding composition of the material, degree of purity and desig...

journal_title：Acta oto-laryngologica

authors： Turck C,Brandes G,Krueger I,Behrens P,Mojallal H,Lenarz T,Stieve M

更新日期：2007-08-01 00:00:00

abstract：CONCLUSION:The technology of stimulation rates between 1500 and 5000 pulses per second per channel (pps/ch) brings a benefit for all users. However, the fastest possible rate does not necessarily lead to best hearing performance in each individual subject. Individual optimization of stimulation rate is recommended. OB...

journal_title：Acta oto-laryngologica

authors： Buechner A,Frohne-Büchner C,Gaertner L,Stoever T,Battmer RD,Lenarz T

更新日期：2010-01-01 00:00:00

abstract：:The practicability of recording auditory nerve and brainstem responses during early childhood is demonstrated. This paper reports our experience with two different electrode locations: ear-canal/ear-lobe and ear-lobe/vertex. The test is performed with a light portable stimulus-generating and response-recording system ...

journal_title：Acta oto-laryngologica

authors： Montandon PB,Cao MH,Engel RT,Grajew T

更新日期：1979-03-01 00:00:00

abstract：INTRODUCTION:This study showed that short and long interval treatments achieved comparable success rates. There was no statistically significant difference in the rate of early and late recurrences between the two groups. Modified Epley maneuver can be applied in a short interval time with comparable success and recurr...

journal_title：Acta oto-laryngologica

authors： Kahraman SS,Yildirim YS,Tugrul S,Ozturan O

更新日期：2017-05-01 00:00:00

abstract：:Although the association between gastroesophageal reflux disease (GERD) and laryngeal disorders in adults is well established there is still a lack of information concerning the true extent of the laryngeal complications of GERD in children. The aim of this study was to determine the laryngeal status of children with ...

journal_title：Acta oto-laryngologica

authors： Zalesska-Krecicka M,Krecicki T,Iwanczak B,Blitek A,Horobiowska M

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:This study was conducted to demonstrate the safety and efficacy of the Otologics Middle Ear Transducer (MET) Ossicular Stimulator and, in particular, to compare the audiologic benefits of this novel form of electromechanical stimulation with those of conventional acoustical amplification. MATERIAL AND METHO...

journal_title：Acta oto-laryngologica

authors： Jenkins HA,Niparko JK,Slattery WH,Neely JG,Fredrickson JM

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To determine the clinical usefulness of the dichotic multiple-frequency (MF) auditory steady-state response (ASSR) technique for estimating normal hearing compared to a 0.5-kHz tone burst and broadband click auditory brainstem response (ABR) protocol in a sample of adults. MATERIAL AND METHODS:A comparative ...

journal_title：Acta oto-laryngologica

authors： Swanepoel D,Schmulian D,Hugo R

更新日期：2004-01-01 00:00:00

abstract：:This study combined ultrastructural and statistical methods to learn the effects of weightlessness on rat utricular maculae. A principle aim was to determine whether weightlessness chiefly affects ribbon synapses of type II cells, since the cells communicate predominantly with branches of primary vestibular afferent e...

journal_title：Acta oto-laryngologica

authors： Ross MD

更新日期：2000-06-01 00:00:00

abstract：CONCLUSION:The chewing gum indirectly affects postural control by influencing vestibular function to stabilize posture during upright standing. OBJECTIVES:This study aimed to evaluate the effect of chewing gum on static posturography in patients. METHODS:The subjects were 26 patients with chronic balance disorders. T...

journal_title：Acta oto-laryngologica

authors： Goto F,Kushiro K,Tsutsumi T

更新日期：2011-11-01 00:00:00

abstract：:The effects of two simulated hearing impairments (presbyacusis) on speech perception were investigated in two groups of normally hearing subjects (30 and 48 subjects, respectively). Eight patients with presbyacusis with similar hearing impairment to those in the latter simulation served as the clinical material. Word ...

journal_title：Acta oto-laryngologica

authors： Sorri M,Huttunen K,Körkkö P,Mäki-Torkko E

更新日期：2000-03-01 00:00:00

abstract：:On-line measurement of ME gas composition in normal middle ears of 5 anesthetized guinea pigs at an established steady state was performed by mass spectrometry. The mean values for the gas composition of the middle ear were found to be: PN2: 82.4%, PO2: 7.6% and PCO2: 10.0%. This composition is very different from tha...

journal_title：Acta oto-laryngologica

authors： Sadé J,Luntz M

更新日期：1993-05-01 00:00:00

abstract：:The embryonic development of the crista ampullaris of the CBA/CBA mouse was followed both in organ culture of explanted inner ears of the 16th gestational day and in vivo from the 16th gestational day until the 21st day, an age corresponding to birth. Cytodifferentiation of the sensory epithelium of the crista ampulla...

journal_title：Acta oto-laryngologica

authors： Nordemar H

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Efficacy of current treatment methods in idiopathic sudden sensorineural hearing loss (ISSNHL) is still unsatisfactory. OBJECTIVE:This study aimed to discover in differences in effect between steroid applications responsible for promoting the prognosis in ISSNHL. MATERIALS AND METHODS:A study was conducted...

journal_title：Acta oto-laryngologica

authors： Jiang K,Li S,Cheng L,Yang J

更新日期：2018-11-01 00:00:00

abstract：CONCLUSIONS:The microarray analysis identified 39 genes up- or down-regulated by dexamethasone in the cultured tissue of mice cochlea. Of the eight genes most highly affected, several are suggested to have protective effects in the traumatized inner ear (Fkbp5, Glucocorticoid-induced leucine zipper (Gilz), glutathione ...

journal_title：Acta oto-laryngologica

authors： Maeda Y,Fukushima K,Hirai M,Kariya S,Smith RJ,Nishizaki K

更新日期：2010-12-01 00:00:00

abstract：CONCLUSION:The incidence of new cases of Meniere's disease (MD) in elderly patients aged 60 years or more was found to have increased over time after correction for age distribution in the overall population. Job- and care-related fatigue may be involved in the recent increase in elderly-onset cases because physical an...

journal_title：Acta oto-laryngologica

authors： Shojaku H,Watanabe Y,Yagi T,Takahashi M,Takeda T,Ikezono T,Ito J,Kubo T,Suzuki M,Takumida M,Takeda N,Furuya N,Yamashita H,Peripheral Vestibular Disorder Research Committee of Japan.

更新日期：2009-02-01 00:00:00

abstract：:Using electron microscopy and GABA immunohistochemistry we evaluated the effects on human embyronic organ of Corti tissue culture of exposure to the ototoxic aminoglycoside antibiotic neomycin at a dose of 1 mM for 48 to 96 hrs. Neomycin induces the formation of multilamellar myeloid structures. These lesions, found o...

journal_title：Acta oto-laryngologica

authors： Mu MY,Pao X,Jie T,Yu YJ

更新日期：1996-11-01 00:00:00

abstract：CONCLUSION:Patients with hiatus hernia can be relieved from H, MSL and MSN by hiatus hernia repair. OBJECTIVE:It has been hypothesized that respiratory symptoms in patients with gastro-oesophageal reflux disease (GORD) may, in some cases, be due to misdirected swallowing as a consequence of defective opening of the up...

journal_title：Acta oto-laryngologica

authors： Mjönes AB,Ledin T,Grahn LT,Hultcrantz E

更新日期：2005-01-01 00:00:00

abstract：CONCLUSION:Chronic subjective dizziness (CSD) is frequent and affects twice as many women as men. Anxiety is a strong predisposing factor. The pathophysiologic concept of this disorder assumes that balance function and emotion share common neurologic pathways, which might explain that the balance disorder can provoke f...

journal_title：Acta oto-laryngologica

authors： Odman M,Maire R

更新日期：2008-10-01 00:00:00

abstract：CONCLUSION:Endolymphatic hydrops could be a reversible inner ear pathological condition. After sac surgery, hydrops was reduced and symptoms went into remission in some cases, although vertigo suppression was not always a result of the reduced hydrops. OBJECTIVE:To examine the changes in endolymphatic hydrops detected...

journal_title：Acta oto-laryngologica

authors： Uno A,Imai T,Watanabe Y,Tanaka H,Kitahara T,Horii A,Kamakura T,Takimoto Y,Osaki Y,Nishiike S,Inohara H

更新日期：2013-09-01 00:00:00

abstract：:Background: In otosclerosis mixed hearing loss is the most frequent symptom and arises when the focus involves the stapes footplate. Surgeons usually prefer to wait a minimum air-bone gap of 25 - 35 dB before surgery.Objectives: To evaluate the outcome of microdrill stapedotomy for otosclerosis in patients with a preo...

journal_title：Acta oto-laryngologica

authors： Canale A,Albera A,Macocco F,Caranzano F,Albera R

更新日期：2020-09-01 00:00:00

abstract：:The change in the EP, CM, SP and AP during perilymphatic perfusion of vasopressin (antidiuretic hormone) was examined in the guinea pig. The EP was recorded with a microelectrode through the spiral ligament of the second turn. The CM, SP and AP were measured with the differential electrodes in the basal turn. The perf...

journal_title：Acta oto-laryngologica

authors： Mori N,Ohta K,Matsunaga T

更新日期：1986-03-01 00:00:00

abstract：CONCLUSION:Idiopathic otolithic vertigo (IOV) with relatively long duration of attacks might be caused by endolymphatic hydrops in the otolith organ. OBJECTIVES:To clarify the pathophysiology underlying IOV, episodic tilting or translational sensation attacks by unknown causes, especially the possibility of endolympha...

journal_title：Acta oto-laryngologica

authors： Murofushi T,Komiyama S,Hayashi Y,Yoshimura E

更新日期：2015-01-01 00:00:00