The alteration of ultrastructure and immunoreactivity of human embryonic organ of Corti tissue culture after exposure to aminoglycoside (neomycin) ototoxicity.

abstract：:Detailed longitudinal studies of speech perception, speech production and language acquisition have justified a significant change in the demographics of congenitally and prelingually deaf children who receive cochlear implants. A trend toward earlier cochlear implantation has been justified by improvements in measure...

journal_title：Acta oto-laryngologica

authors： Miyamoto RT,Kirk KI,Svirsky MA,Sehgal ST

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVES:To assess the relationships between CD163 expression, localization of CD163+ macrophages, clinicopathological features and prognosis of NPC. METHODS:A total of 110 cases of NPC specimens and 80 cases of nasopharyngitis specimens were analysed for CD163 expression by immunohistochemistry and EBERs expression...

journal_title：Acta oto-laryngologica

authors： Huang H,Liu X,Zhao F,Lu J,Zhang B,Peng X,Zhang M,Chen X,Li G,Li X

更新日期：2017-08-01 00:00:00

abstract：:An X-ray energy dispersive analysis was performed on the mature serial sectioned freeze-dried mammalian labyrinth (CBA/CBA mouse). The elemental distribution in the endolymphatic and perilymphatic spaces revealed similar results as have been reported in the literature when withdrawing fluid for microanalysis. The cupu...

journal_title：Acta oto-laryngologica

authors： Anniko M,Wroblewski R

更新日期：1980-11-01 00:00:00

abstract：:Although doxorubicin [adriamycin (ADM)] ototoxicity has not been detected to date, it has been reported that neurotoxicity in the central nervous system was induced by chemotherapy with ADM in patients receiving chronic cyclosporin A (CsA) treatment. ADM ototoxicity may be induced by combination therapy with CsA becau...

journal_title：Acta oto-laryngologica

authors： Saito T,Zhang ZJ,Tokuriki M,Shibamori Y,Yamamoto T,Noda I,Ohtsubo T,Saito H

更新日期：2001-10-01 00:00:00

abstract：CONCLUSIONS:Concurrent chemoradiotherapy with carboplatin and uracil-f tegafur (UFT) seems to be a promising and appropriate regimen for patients with poor performance status (PS) with locally advanced squamous cell carcinoma of the head and neck (SCCHN). OBJECTIVE:We designed a regimen based on divided low-dose admin...

journal_title：Acta oto-laryngologica

authors： Katori H,Tsukuda M,Taguchi T

更新日期：2007-10-01 00:00:00

abstract：CONCLUSION:Our results suggest that patients with migraine or tension-type headache have subclinical deviations of the subjective visual vertical, which may be associated with their subjective imbalance. OBJECTIVES:Patients affected by migraine or tension-type headache often complain of unsteadiness. However, they rar...

journal_title：Acta oto-laryngologica

authors： Asai M,Aoki M,Hayashi H,Yamada N,Mizuta K,Ito Y

更新日期：2009-01-01 00:00:00

abstract：CONCLUSION:Speech thresholds measured using Cantonese Hearing in Noise Test (CHINT) and cortical evoked response audiometry (CERA) thresholds were highly correlated with pure-tone behavioral results. Both tests are considered to provide good estimates of hearing thresholds and can be employed to confirm the degree of h...

journal_title：Acta oto-laryngologica

authors： Wong LL,Cheung C,Wong EC

更新日期：2008-06-01 00:00:00

abstract：:The DBA/2 strain of mice have genetically induced vestibular dysfunction that presents grossly at an early age as circling behavior and abnormal righting reflexes. The vestibular morphology of this strain has not previously been examined. DBA/2 mice of different ages that showed circling behavior were sacrificed and t...

journal_title：Acta oto-laryngologica

authors： Bloom D,Hultcrantz M

更新日期：1994-07-01 00:00:00

abstract：CONCLUSION:The present study demonstrated the robustness of VEMP testing with toneburst stimuli, since it is hardly affected by head position, i.e. base or tonic excitation levels of the saccule and inferior vestibular nerve. However, the small but highly significant difference found in latency should not be neglected:...

journal_title：Acta oto-laryngologica

authors： Ito K,Karino S,Murofushi T

更新日期：2007-01-01 00:00:00

abstract：:Background: Betahistine is used worldwide to treat patients with Menière's disease. However, despite it being used for decades, diverging opinions on the effect of betahistine on Menière's symptomatology still exist.Aims: The objective of this systematic review was to provide an overview and rate the certainty of the ...

journal_title：Acta oto-laryngologica

authors： Devantier L,Hougaard D,Händel MN,Liviu-Adelin Guldfred F,Schmidt JH,Djurhuus B,Callesen HE

更新日期：2020-10-01 00:00:00

abstract：:Background: Odontogenic sinusitis (OS) is a common but underdiagnosed form of acute rhinosinusitis (ARS). OS carries no specific characteristics, but unilateral symptoms and certain microbiological as well as radiological findings indicate odontogenic origin. Aims/objectives: We studied the proportion of OS in ARS pat...

journal_title：Acta oto-laryngologica

authors： Wuokko-Landén A,Blomgren K,Välimaa H

更新日期：2019-09-01 00:00:00

abstract：:The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Tr...

journal_title：Acta oto-laryngologica

authors： Mohammed el R,Profant M

更新日期：2011-06-01 00:00:00

abstract：CONCLUSION:A 20 mm hole made backwards from the midpoint of the asterion to the mastoid process is suitable for a retrosigmoid keyhole approach with the aid of an endoscope. The endoscope-assisted retrosigmoid keyhole approach can be considered an effective and safe method for removal of vestibular schwannoma. OBJECTI...

journal_title：Acta oto-laryngologica

authors： Sun JQ,Sun JW

更新日期：2013-11-01 00:00:00

abstract：CONCLUSION:Nasal obstruction, rhinorrhea, and the amount of rhinorrhea that confidently reflect the parasympathetic stimulation can be used to more precisely predict nonspecific nasal hyper-reactivity (NHR). OBJECTIVE:We aimed to identify factors that confidently reflected the presence and the degree of NHR, measured ...

journal_title：Acta oto-laryngologica

authors： Kim YH,Jang TY

更新日期：2012-10-01 00:00:00

abstract：:This paper describes an investigation performed to study the middle ear events ensuing from Staphylococcus aureus induced infection in the middle ear cavity of the rat. To obtain an evaluation at both the cell and the tissue level, scanning electron microscopy, transmission electron microscopy and histology were used....

journal_title：Acta oto-laryngologica

authors： Grote JJ,van Blitterswijk CA

更新日期：1984-09-01 00:00:00

abstract：:The effects of transdermally administered scopolamine (TTS-scopolamine) (release rate 5 micrograms/h, one and two patches) and dimenhydrinate (100 mg) on caloric, angular acceleration induced and optokinetic nystagmus were examined in 16 volunteers in a randomized double-blind study. All drugs induced a statistically ...

journal_title：Acta oto-laryngologica

authors： Pyykkö I,Schalén L,Matsuoka I

更新日期：1985-05-01 00:00:00

abstract：:While cigarette smoking and alcohol consumption are recognized covariates for head and neck squamous cell carcinoma (SCC), the role of genetic factors in determining individual susceptibility is unknown. The human tumour necrosis factor (TNF) region on chromosome 6p21 within the major histocompatibility complex (MHC) ...

journal_title：Acta oto-laryngologica

authors： Matthias C,Jahnke V,Fryer A,Strange R,Ollier W,Hajeer A

更新日期：1998-03-01 00:00:00

abstract：:The biocompatibility of commercially available polyimides was examined in relation to the sensory and neural structures of the cochlea. Thin films of four different polyimides were prepared as substrates for photolithographically produced scala tympani electrode arrays and implanted in 32 cat cochleae. Following at le...

journal_title：Acta oto-laryngologica

authors： Haggerty HS,Lusted HS

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To quantitatively analyze modifications of the paratubal muscles in developing Wistar rats following nasal obstruction. MATERIAL AND METHODS:Twenty-four Wistar rats were used. Twelve were examined at 6, 8 and 12 weeks after birth and were considered normal controls. The nostrils of the remaining 12 rats were...

journal_title：Acta oto-laryngologica

authors： Scarano E,Fetoni AR,Picciotti P,Cadoni G,Galli J,Paludetti G

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To develop a large animal model for studies of laryngeal abductor reinnervation. MATERIAL AND METHODS:Six minipigs underwent unilateral anastomosis of the phrenic nerve-abductor branch of the recurrent laryngeal nerve (RLN). Polyhydroxybutyrate (PHB) conduits were used for repair. At each of 30, 60 and 120 d...

journal_title：Acta oto-laryngologica

authors： Birchall M,Idowu B,Murison P,Jones A,Burt R,Ayling S,Stokes C,Pope L,Terenghi G

更新日期：2004-09-01 00:00:00

abstract：CONCLUSIONS:These findings are in line with previous data on the horizontal vestibulo-ocular reflex (VOR) from this laboratory and suggest that eye position signals do not modulate natural vestibular responses. Hence, the Alexander's law (AL) phenomenon cannot be interpreted simply as a consequence of vestibular or ocu...

journal_title：Acta oto-laryngologica

authors： Anastasopoulos D,Anagnostou E

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Acquired centralized tinnitus (ACT) is the most frequent type of chronic tinnitus. We introduce a cognitive neurophysiological ACT hypothesis based on centralized cognitive sensitization processes. MATERIAL AND METHODS:Published cognitive sensitization processes were reviewed using PubMed. Furthermore, a Coc...

journal_title：Acta oto-laryngologica

authors： Zenner HP,Zalaman IM

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:The prognostic factors of facial paralysis complicated by middle ear cholesteatoma (MEC) are largely unknown due to limited reports and smaller sample size. OBJECTIVES:This study aimed to analyze prognostic factors of postoperative outcomes of facial paralysis complicated by MEC. MATERIAL AND METHODS:Clini...

journal_title：Acta oto-laryngologica

authors： Li Q,Jia Y,Feng Q,Tang B,Luo X,Xu P,Wang D,Zhang X

更新日期：2019-02-01 00:00:00

abstract：CONCLUSIONS:The expression of phosphorylcholine (ChoP) in the surface of nontypeable Haemophilus influenzae (NTHi) is an important factor in the pathogenesis of persistent otitis media with effusion (OME) in humans. OBJECTIVES:Lipooligosaccharide (LOS) in NTHi undergoes phase variation in expression of the ChoP epitop...

journal_title：Acta oto-laryngologica

authors： Fujita K,Hirano T,Kodama S,Suzuki M

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Many patients with coronavirus disease 2019 (COVID-19) complain from olfactory dysfunction (OD). Aims/objectives: To evaluate the prevalence, prognosis, and recovery from OD in COVID-19 patients. MATERIAL AND METHODS:In this study, patients with COVID-19 symptoms who were referred to six different tertiary ...

journal_title：Acta oto-laryngologica

authors： Samimi Ardestani SH,Mohammadi Ardehali M,Rabbani Anari M,Rahmaty B,Erfanian R,Akbari M,Motedayen Z,Samimi Niya F,Aminloo R,Farahbakhsh F,Hosseininasab A,Hassanlouei B,Rezaian N,Mokhtari Z

更新日期：2020-11-11 00:00:00

abstract：:Frozen tissue sections of biopsies from head and neck squamous cancer lesions were examined for immunohistochemical staining with a recently developed monoclonal antibody, designated as SQM1 antibody and directed against the surface membrane of squamous carcinoma cells. SQM1 antibody stained selectively squamous carci...

journal_title：Acta oto-laryngologica

authors： Böheim K,Schwarzfurtner H,Böheim C,Frei E 3rd,Bernal SD

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVES:In this paper we test the concept of combining electrical stimulation for high-frequency sound with acoustic hearing for low-frequency information in the same ear. In addition, we test whether residual hearing can be preserved when an electrode is placed up to 10 mm into the inner ear, and whether the site o...

journal_title：Acta oto-laryngologica

authors： Gantz BJ,Turner C

更新日期：2004-05-01 00:00:00

abstract：CONCLUSION:Salivary stones in the parotid gland that are not amenable to endoscopic extraction can safely be removed by a combined, endoscopic-external approach. OBJECTIVE:Limitations for endoscopic removability of salivary stones from the parotid gland are immobile stones in the deeper salivary duct system. A combine...

journal_title：Acta oto-laryngologica

authors： Mikolajczak S,Bremke M,Beutner D,Luers JC

更新日期：2015-01-01 00:00:00

abstract：:We previously reported that long-term exposure to glutamate (Glu) induced death of cochlear outer hair cells (OHCs). However, the mechanisms of OHC death induced by Glu were unclear. In the central nervous system, Glu is known to interfere with a cystine-Glu antiporter, leading to a decrease in cystine uptake and redu...

journal_title：Acta oto-laryngologica

authors： Sunami K,Yamane H,Takayama M,Nakagawa T,Konishi K,Iguchi H

更新日期：1999-01-01 00:00:00

abstract：:Eighteen patients with intracranial skull base tumours diagnosed at CT or MR as neuromas or meningiomas were studied with positron emission tomography (PET) using L-(methyl-11C) methionine. Compared with normal cerebellar tissue, the uptake of methionine in the tumours increased more rapidly and reached a higher level...

journal_title：Acta oto-laryngologica

authors： Nyberg G,Bergström M,Enblad P,Lilja A,Muhr C,Långström B

更新日期：1997-07-01 00:00:00