Histological evaluation of novel ossicular chain replacement prostheses: an animal study in rabbits.

abstract：OBJECTIVE:The aim of this double-blind, randomized, multicenter study was to compare the efficacy of betahistine dihydrochloride (BH) and flunarizine (FL) using the Dizziness Handicap Inventory (DHI), a validated self-assessment questionnaire that has not previously been used in a clinical trial to evaluate antivertigo...

journal_title：Acta oto-laryngologica

authors： Albera R,Ciuffolotti R,Di Cicco M,De Benedittis G,Grazioli I,Melzi G,Mira E,Pallestrini E,Passali D,Serra A,Vicini C

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The balloon catheter has been used for a decade to dilate paranasal sinus outflow tracts. The question is: how wide and how durable is the dilation of drainage pathways in patients in long-term observations after this procedure? OBJECTIVE:The objective of our study was to observe the changes occurring in th...

journal_title：Acta oto-laryngologica

authors： Szczygielski K,Galusza B,Rapiejko P,Klopotek M,Jurkiewicz D

更新日期：2017-09-01 00:00:00

abstract：:We previously reported that long-term exposure to glutamate (Glu) induced death of cochlear outer hair cells (OHCs). However, the mechanisms of OHC death induced by Glu were unclear. In the central nervous system, Glu is known to interfere with a cystine-Glu antiporter, leading to a decrease in cystine uptake and redu...

journal_title：Acta oto-laryngologica

authors： Sunami K,Yamane H,Takayama M,Nakagawa T,Konishi K,Iguchi H

更新日期：1999-01-01 00:00:00

abstract：CONCLUSION:This study described objective and subjective evaluations of the Nurotron® Venus™ Cochlear Implant System and indicated that this system produced a satisfactory performance. OBJECTIVE:To observe the performance of the Nurotron® Venus™ cochlear implant (CI) system via electrophysiological and psychophysical ...

journal_title：Acta oto-laryngologica

authors： Gao N,Xu XD,Chi FL,Zeng FG,Fu QJ,Jia XH,Yin YB,Ping LC,Kang HY,Feng HH,Wu YZ,Jiang Y

更新日期：2016-01-01 00:00:00

abstract：CONCLUSION:Vestibular disturbance is frequent, but mild even immediately after stapes surgery. Vestibular symptoms improved or disappeared quickly, and they did not correlate with nystagmus. Outpatient stapes surgery performed under local anaesthesia is a feasible approach. OBJECTIVE:Vestibular symptoms are common and...

journal_title：Acta oto-laryngologica

authors： Hirvonen TP,Aalto H

更新日期：2013-08-01 00:00:00

abstract：:POLGON (Polarized light goniometer) was used to evaluate ataxia during stepping movements in patients with spinocerebellar degeneration (SCD) and Parkinson's disease. The measurements included mean angular change of shoulders (M.A.C.S.) and its coefficient of variation (C.V.). In patients with SCD, the values of M.A.C...

journal_title：Acta oto-laryngologica

authors： Sasaki O,Taguchi K,Kikukawa M,Ogiba T

更新日期：1993-07-01 00:00:00

abstract：:Organophosphorus compounds in the form of insecticides are in widespread use and have recently attracted considerable interest as environmentally toxic agents. As little is known about the effect of environmental toxins on the tubal function in the ear, we studied the middle ear pressure necessary to force the eustach...

journal_title：Acta oto-laryngologica

authors： Bergler W,Juncker C,Petroianu G,Keilmann A,Hörmann K

更新日期：1995-07-01 00:00:00

abstract：CONCLUSION:The existence of patients with positive non-sentinel node indicates a risk of misdiagnosis of metastasis in oropharyngeal and oral cancer. OBJECTIVES:We attempted to confirm the usefulness of sentinel lymph node biopsy (SLNB) in oropharyngeal and oral cavity cancer to detect clinically occult metastases. P...

journal_title：Acta oto-laryngologica

authors： Santaolalla F,Sanchez JM,Ereño C,Gonzalez A,Rodriguez ML,Sanchez A,Martinez A

更新日期：2008-10-01 00:00:00

abstract：:We studied three-dimensional arrangement of collagen fibers and elastic fibers in the human vocal fold by scanning electron microscopy after digesting cellular elements and collagen fibers with formic acid treatment and cellular elements and elastic fibers with 10% sodium hydroxide. The superficial layer consisted of ...

journal_title：Acta oto-laryngologica

authors： Ishii K,Zhai WG,Akita M,Hirose H

更新日期：1996-09-01 00:00:00

abstract：CONCLUSION:Our results demonstrate for the first time a potentially enhanced basal secretion of monocyte chemoattractant protein-1 (MCP-1) and interleukin (IL)-17A-stimulated secretion of IL-6 from nasal polyp fibroblasts, enhanced basal secretion of IL-6 from eosinophilic nasal polyp fibroblasts, and a remarkable up-r...

journal_title：Acta oto-laryngologica

authors： Homma H,Kamiya K,Kusunoki T,Ikeda K

更新日期：2013-10-01 00:00:00

abstract：CONCLUSIONS:Intratympanic steroid (ITS) treatment groups exhibited better outcomes in PTA improvement and recovery rate than systemic steroid therapy (SST) groups. Whether initial hearing loss severity would influence the PTA improvement and recovery rate still requires further research. OBJECTIVE:This article was aim...

journal_title：Acta oto-laryngologica

authors： Qiang Q,Wu X,Yang T,Yang C,Sun H

更新日期：2017-06-01 00:00:00

abstract：CONCLUSION:Low-dose administration of Aspartame (Ap) did not produce a significant ototoxic effect at the end of the 6th month. However, duration of the ototoxic effect is shortened and severity of the effect is increased as dose and duration of Ap administration is increased. OBJECTIVES:While Ap toxicity has been stu...

journal_title：Acta oto-laryngologica

authors： Ozturan O,Dogan R,Tugrul S,Gedik O,Sjostrand AP,Yildirim YS

更新日期：2017-04-01 00:00:00

abstract：CONCLUSION:Cochlear implantation (CI) for Japanese single-sided deafness patients resulted in improved speech perception, increased sound localization accuracy, and reduced tinnitus handicap. OBJECTIVES:This study reports results for five adult SSD cases with CI, focusing on the benefits they obtained in terms of spee...

journal_title：Acta oto-laryngologica

authors： Kitoh R,Moteki H,Nishio S,Shinden S,Kanzaki S,Iwasaki S,Ogawa K,Usami S

更新日期：2016-01-01 00:00:00

abstract：:Topical application of FGF (fibroblast growth factor), a potent mitogen for mesodermal and neuroectodermal cells, was given to promote the healing of tympanic membrane perforations in rats. Calibrated tympanic membrane perforations were performed in 30 rats. At day 0, each rat received 40 microliters of placebo in the...

journal_title：Acta oto-laryngologica

authors： Mondain M,Saffiedine S,Uziel A

更新日期：1991-01-01 00:00:00

abstract：CONCLUSION:Our numerical simulation model provides an accurate reflection of nasal airflow, and the results were validated by clinical measurements. OBJECTIVES:To evaluate the accuracy of a numerical simulation model of nasal airflow. METHODS:Ten volunteers with normal nasal cavities underwent CT, acoustic rhinometry...

journal_title：Acta oto-laryngologica

authors： Lu J,Han D,Zhang L

更新日期：2014-05-01 00:00:00

abstract：CONCLUSION:Each of eight patients with bilateral microtia and atresia underwent bilateral reconstruction of the auricles and external auditory canals and were fitted bilateral canal-type hearing aids in the operated ears to replace a bone conduction hearing aid. The ability to discriminate inter-aural intensity differe...

journal_title：Acta oto-laryngologica

authors： Kaga K,Asato H

更新日期：2017-04-01 00:00:00

abstract：CONCLUSION:Delayed facial palsy after tympanoplasty had no predisposition for gender or side. It seemed that prednisolone alone without antiviral drugs was enough for the treatment of delayed facial palsy after tympanoplasty. OBJECTIVE:To analyze the clinical characteristics and prognosis of delayed facial palsy after...

journal_title：Acta oto-laryngologica

authors： Zhou Y,Song R,Li Y

更新日期：2015-02-01 00:00:00

abstract：:The most common cause of seasonal allergic rhinitis in Japan is the Japanese cedar (JC). Recently, a pullulan-conjugated antigen (CS-560) has been developed to reduce adverse effects and to enhance the effect of JC-specific immunotherapy (IT). If the mechanism of IT can be fully elucidated and the treatment can be use...

journal_title：Acta oto-laryngologica

authors： Nakano A,Nakano K,Okawa T,Yamakoshi T,Terada N,Numata T,Konno A

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The most crucial clinical problem of Eosinophilic Otitis Media (EOM) is sensorineural hearing loss. A previous report revealed that repeated antigen stimulation of middle ear causes eosinophilic inflammation not only in the middle ear but also in the inner ear. OBJECTIVE:The purpose of the present study was...

journal_title：Acta oto-laryngologica

authors： Kudo N,Matsubara A,Nishizawa H,Miura T

更新日期：2017-05-01 00:00:00

abstract：CONCLUSION:Lactobacillus rhamnosus GG (L.GG) was present in all adenoids of children receiving the L. GG product. However, since L.GG was also found from the placebo group, one cannot confirm its effect on the occurrence of rhinovirus (RV) or enterovirus (EV). OBJECTIVES:The present study was conducted to determine wh...

journal_title：Acta oto-laryngologica

authors： Swanljung E,Tapiovaara L,Lehtoranta L,Mäkivuokko H,Roivainen M,Korpela R,Pitkäranta A

更新日期：2015-08-01 00:00:00

abstract：:An analysis of auditory brainstem response (ABR) thresholds and ABR-based frequency tuning curves was performed in 15 Sprague-Dawley rats exposed to Haemophilus influenzae type b endotoxin; 5 microg/50 microl toxin was instilled every second day, altogether five times, into the middle ear cavity through a small perfor...

journal_title：Acta oto-laryngologica

authors： Stenqvist M,Anniko M,Pettersson A

更新日期：1997-05-01 00:00:00

abstract：:This study combined ultrastructural and statistical methods to learn the effects of weightlessness on rat utricular maculae. A principle aim was to determine whether weightlessness chiefly affects ribbon synapses of type II cells, since the cells communicate predominantly with branches of primary vestibular afferent e...

journal_title：Acta oto-laryngologica

authors： Ross MD

更新日期：2000-06-01 00:00:00

abstract：CONCLUSION:This study showed that elective neck dissection (ND) resulted in reduced regional recurrences in a selected group of surgically treated patients with pT1-2 carcinomas but did not show any benefit for disease-specific survival (DSS). Furthermore, the importance of pN classification was also verified for this ...

journal_title：Acta oto-laryngologica

authors： Psychogios G,Mantsopoulos K,Koch M,Klintworth N,Kapsreiter M,Zenk J,Iro H

更新日期：2013-03-01 00:00:00

abstract：:The ultrastructure of the geniculate ganglion was studied in the guinea pig and monkey. Two cytologically distinct colonies of ganglion cells were seen and identified as light and dark cells. All neurons were unmyelinated and most were unipolar, although a few bipolar cells were seen. The axons, upon leaving the cell ...

journal_title：Acta oto-laryngologica

authors： Kitamura K,Kimura RS,Schuknecht HF

更新日期：1982-01-01 00:00:00

abstract：CONCLUSION:The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests a compensation for the decreased amount of saliva secretion associated with age progression. OBJECTIVE:To investigate the change in aquaporin-1 (AQP1) and aquaporin-5 (AQP5) expression in the sa...

journal_title：Acta oto-laryngologica

authors： Sapmaz E,Uysal M,Tumer MK,Sapmaz HI,Somuk BT,Arici A,Tas U

更新日期：2016-09-01 00:00:00

abstract：:The effects of transdermally administered scopolamine (TTS-scopolamine) (release rate 5 micrograms/h, one and two patches) and dimenhydrinate (100 mg) on caloric, angular acceleration induced and optokinetic nystagmus were examined in 16 volunteers in a randomized double-blind study. All drugs induced a statistically ...

journal_title：Acta oto-laryngologica

authors： Pyykkö I,Schalén L,Matsuoka I

更新日期：1985-05-01 00:00:00

abstract：CONCLUSION:Salivary gland diseases should be handled with a high index of suspicion. Although an inference could be drawn it is not clear from this study if primary head and neck cancers (HNCs) have a significant association with HIV/AIDS. OBJECTIVE:HIV/AIDS manifestations and malignancies do occur in the head and nec...

journal_title：Acta oto-laryngologica

authors： Nwaorgu O,Kokong D,Onakoya P,Adoga S,Ibekwe T

更新日期：2007-11-01 00:00:00

abstract：CONCLUSION:Videomicroscopy with subpixel analysis is an excellent system for quantification of outer hair cell (OHC) movements. The resolution of a few nanometers is accurate enough to show induced differences of electromotility. OBJECTIVE:Electromotility of OHCs is a voltage-dependent process resulting from a membran...

journal_title：Acta oto-laryngologica

authors： Canis M,Ortner M,Olzowy B,Jahn K,Strupp M,Hemmert W,Berghaus A,Suckfuell M

更新日期：2008-03-01 00:00:00

abstract：:Synchronous benign and malignant tumors in the ipsilateral salivary glands are extremely rare. We report a unique case of synchronous unilateral parotid tumors in a 71-year-old man. The main parotid lesion was preoperatively suggested to be adenocarcinoma by fine needle aspiration cytology. A coexisting Warthin's tumo...

journal_title：Acta oto-laryngologica

authors： Roh JL,Kim JM,Park CI

更新日期：2007-01-01 00:00:00

abstract：:Transitory hearing impairment has been well documented in humans during basilar migraine attacks. Ischemia induced by activation of central nervous system adrenoreceptors by cAMP is one of the mechanisms that has been implicated, as well as calcium metabolism alterations. Propranolol-HCl has proven to be an effective ...

journal_title：Acta oto-laryngologica

authors： Bernard PA,Bourret CS,Stenstrom R

更新日期：1991-01-01 00:00:00