Abstract:
:On-line measurement of ME gas composition in normal middle ears of 5 anesthetized guinea pigs at an established steady state was performed by mass spectrometry. The mean values for the gas composition of the middle ear were found to be: PN2: 82.4%, PO2: 7.6% and PCO2: 10.0%. This composition is very different from that of atmospheric air, and very similar to the gas composition of mixed venous blood. Our conclusions are that the gas composition is basically controlled by interchange with gases present in the blood and not by introduction of air through the eustachian tube. It is therefore proposed that middle ear gas deficiency is secondary not to eustachian tube input failure but to excess loss of middle ear gas due to enhanced diffusion into the blood. This situation exists especially under inflammatory conditions when there is an enlarged number of blood vessels promoting increased gas diffusion into them. Under ordinary conditions this middle ear gas deficiency will probably cause no significant underpressure because the mastoid pneumatization will act as a pressure buffer. When mastoid pneumatization is lacking, as happens in the otitis media syndrome, a pathological negative pressure will ensue.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Sadé J,Luntz Mdoi
10.3109/00016489309135824subject
Has Abstractpub_date
1993-05-01 00:00:00pages
353-7issue
3eissn
0001-6489issn
1651-2251journal_volume
113pub_type
杂志文章abstract::To investigate whether the crossed olivo-cochlear bundle (COCB) functions in a protective manner, albino guinea pigs were exposed to sounds of varying intensity (110-130 dB SPL, 3-30 min) with or without electric stimulation of COCB, and the threshold shifts of the compound action potential (CAP) were examined. A stat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1992.11665405
更新日期:1992-01-01 00:00:00
abstract::Juvenile nasopharyngeal angiofibroma is a disease afflicting mainly adolescent males. The lesion is benign but characterized by local aggressive growth. In advanced cases the tumour may extend intracranially. In this study 18 cases of juvenile nasopharyngeal angiofibroma were investigated. Tumour extension was assesse...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809119456
更新日期:1988-01-01 00:00:00
abstract::During the period 1967-1985, 95 primary tracheal carcinomas occurred in Finland. The mean annual incidence rate was one per one million inhabitants, the male:female ratio being 7:3. There was a significant increase of the disease by increasing age with the exception of 70-79 years. The most common location was the low...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109100772
更新日期:1991-01-01 00:00:00
abstract::In the last few years the use of ABR in the dysmetabolic encephalopathies has aroused considerable interest. Even though brainstem involvement in these syndromes is not yet entirely understood, ABR techniques have provided new and important insights. We studied 60 insulin-dependent diabetic subjects, 29 females and 31...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain obscure. When late embryonic or early postnatal rat organs of Corti we...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300043325
更新日期:2001-01-01 00:00:00
abstract:CONCLUSION:The results support that chronic electromagnetic field exposure may cause damage by leading to neuronal degeneration of the auditory system. OBJECTIVES:Numerous researches have been done about the risks of exposure to the electromagnetic fields that occur during the use of these devices, especially the effe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1032434
更新日期:2015-08-01 00:00:00
abstract::Nerve and cortical input convergence patterns, representing the fore- and hindlimb, were studied in single cells located in the lateral vestibular nucleus of the cat. Deitersian cells responded with excitation to cortical stimulation with a latency ranging from 4 to 14 msec, while responses ranged from 9 to 12 msec to...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309130942
更新日期:1983-03-01 00:00:00
abstract::Losses (determined by measuring microphonic responses) were essentially identical, regardless of whether produced by admittance of sound into the middle ear via perforations in the tympanic membrane (TM) or in the bulla. With SPLs monitored directly at the TM, losses increased at 12 dB/oct with inverse frequency for f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609119970
更新日期:1976-03-01 00:00:00
abstract::Alloplastic materials have been used in middle ear reconstruction since 1952. Biologically, biomaterials and specifically ceramics can be defined as being bioinert, bioactive or biodegradable; these terms being descriptive of the biochemical response provoked by the material in the host tissue. Various ceramics, carbo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1992.11665426
更新日期:1992-01-01 00:00:00
abstract:CONCLUSIONS:The incidence rate of hypothyroidism after treatment for laryngeal and hypopharyngeal cancer is high, especially after combination treatment. An association between hypothyroidism and autoantibodies was found. OBJECTIVES:The incidences of hypothyroidism and autoantibodies were assessed retrospectively in 1...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600818096
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001042
更新日期:2003-01-01 00:00:00
abstract::The object of this study was to assess the contributions of various cranial nerve nuclei to the short latency vestibular evoked potentials (VsEPs) in cat. The following nuclei were investigated: vestibular nuclei, and 3rd, 6th and 10th cranial nerve nuclei. In unilateral labyrinthectomized cats, suboccipital craniecto...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139277
更新日期:1995-03-01 00:00:00
abstract:CONCLUSION:This 3D prototyped model constructed using a selective laser sintering method serves as a good material for surgical simulation of a malformed ear. OBJECTIVE:In order to perform surgery of the malformed ear, a thorough understanding of the anatomy of the ear is required, together with sufficient experience....
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016874
更新日期:2005-01-01 00:00:00
abstract::Serially cultivated rat middle ear epithelium was studied under exposure to various concentrations of carbon dioxide. Three experiments were performed exposing the epithelium to a gaseous environment containing 5 or 10% CO2 or to an atmosphere almost devoid of CO2. Oxygen was maintained constant at 20% and nitrogen wa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009125165
更新日期:1990-05-01 00:00:00
abstract::Background: Odontogenic sinusitis (OS) is a common but underdiagnosed form of acute rhinosinusitis (ARS). OS carries no specific characteristics, but unilateral symptoms and certain microbiological as well as radiological findings indicate odontogenic origin. Aims/objectives: We studied the proportion of OS in ARS pat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1634837
更新日期:2019-09-01 00:00:00
abstract::In order to determine the characteristics of the vestibulo-ocular reflexes (VORs) as a function of age and posturo-motor development, a group of 26 normal children (6 to 25 months old) were tested at three different stages of posturo-motor control: prior to as well as during the first attempts to walk without support,...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Recent studies have implicated nitric oxide (NO) in neuronal degeneration and plasticity in the motor nervous system. In the present study, we investigated the induction of nitric oxide synthase (NOS) in the motoneurons in the nucleus ambiguus (NA) after injury to the rat recurrent laryngeal nerve (RLN) using nicotina...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750001198
更新日期:2000-03-01 00:00:00
abstract::Preyer's reflex, the elicitation of startle response to auditory stimuli, has been widely used for the evaluation of hearing in rodents and other animals. Surprisingly, however, the sensitivity and specificity of Preyer's reflex in the assessment of hearing has not been adequately studied. The aim of this study was to...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract:CONCLUSION:From aspect of fluid dynamics, expanding patients' nasopharyngeal coronal-sectional area to 48.3-54.7% of normal area will bring the airflow velocity back to normal in adenoidal hypertrophy children. It might provide a suggestion for adenoidectomy range selection and whether total resection is necessary. OB...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1212266
更新日期:2017-01-01 00:00:00
abstract::There is evidence that GABA acts as the excitatory neurotransmitter at synapses between vestibular hair cells and the afferent fibres in the mammalian labyrinth. The question arose as to whether certain vestibular dysfunctions such as labyrinthine vertigo could be treated in patients by influencing the peripheral GABA...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130882
更新日期:1982-01-01 00:00:00
abstract::Thirty-nine cases of congenital facial asymmetry, in which one corner of the mouth does not dip downward symmetrically with the other, are presented. The author has termed this condition 'congenital unilateral lower lip palsy' (CULLP). CULLP was the most frequent condition in congenital facial anomalies seen in our cl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909137173
更新日期:1979-01-01 00:00:00
abstract::It is known that 15-20% of oropharyngeal carcinomas develop distant metastases that involve most commonly lung, liver and bone. Clival metastasis from oropharyngeal squamous cell carcinoma has not been previously reported in the English literature. We describe the rare occurrence of clival metastasis from tonsillar ca...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701687283
更新日期:2008-06-01 00:00:00
abstract::Glyconjugate expression in formalin-fixed, paraffin-embedded Sjögren's syndrome labial glands (nine cases) was compared with that in normal glands (12 samples) using a wide panel of lectins. Mucous cells expressed mainly mucous-type glycoproteins including sialyl, fucosyl, galactosyl and galactosaminosyl residues, and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709114217
更新日期:1997-11-01 00:00:00
abstract:CONCLUSION:Mouse embryonic stem cells (ESCs) transplanted into the scala tympani are able to migrate in the cochlea of rats deafened with aminoglycoside and partly restore the structure of sensory epithelia of the inner ear. OBJECTIVES:To explore the migration and differentiation of enhanced green fluorescence protein...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.720029
更新日期:2013-02-01 00:00:00
abstract:CONCLUSION:Continuous positive airway pressure (CPAP) therapy improved not only apnea-hypopnea during sleep and sleep structure but also sleep-related deglutition, especially respiratory phase patterns associated with deglutition. OBJECTIVES:Sleep-related deglutition and related respiratory phase patterns in patients ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.520166
更新日期:2011-02-01 00:00:00
abstract::To predict the possible benefit of a cochlear implant to a patient, the clinician requires a reliable objective method to monitor the presence of surviving fibres in the 8th nerve. The subjective promontory test and the evaluation of electrically evoked brainstem potentials are not adequate. An electrical stimulus art...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126093
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:The balloon catheter has been used for a decade to dilate paranasal sinus outflow tracts. The question is: how wide and how durable is the dilation of drainage pathways in patients in long-term observations after this procedure? OBJECTIVE:The objective of our study was to observe the changes occurring in th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1300941
更新日期:2017-09-01 00:00:00
abstract::The occurrence of artifactual morphological changes was investigated in human eighth nerve biopsies and corresponding changes were brought about in biopsies from rats by mechanical handling before fixation. At the very site of compression by a pair of forceps the biopsy stained lighter than in its immediate surroundin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127111
更新日期:1980-01-01 00:00:00
abstract::The biocompatibility of commercially available polyimides was examined in relation to the sensory and neural structures of the cochlea. Thin films of four different polyimides were prepared as substrates for photolithographically produced scala tympani electrode arrays and implanted in 32 cat cochleae. Following at le...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127474
更新日期:1989-01-01 00:00:00
abstract::A homozygous mutant rat at the white spotting (Ws) locus showing a deficiency of melanocytes has recently been found (4, 5). The function and morphology of the inner ear of the Ws/Ws rat were examined by auditory brainstem response (ABR), endocochlear DC potential (EP), and electron microscopy. The mean ABR threshold ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126038
更新日期:1994-03-01 00:00:00