Dynamic measurement of gas composition in the middle ear. II: Steady state values.

Abstract:

:On-line measurement of ME gas composition in normal middle ears of 5 anesthetized guinea pigs at an established steady state was performed by mass spectrometry. The mean values for the gas composition of the middle ear were found to be: PN2: 82.4%, PO2: 7.6% and PCO2: 10.0%. This composition is very different from that of atmospheric air, and very similar to the gas composition of mixed venous blood. Our conclusions are that the gas composition is basically controlled by interchange with gases present in the blood and not by introduction of air through the eustachian tube. It is therefore proposed that middle ear gas deficiency is secondary not to eustachian tube input failure but to excess loss of middle ear gas due to enhanced diffusion into the blood. This situation exists especially under inflammatory conditions when there is an enlarged number of blood vessels promoting increased gas diffusion into them. Under ordinary conditions this middle ear gas deficiency will probably cause no significant underpressure because the mastoid pneumatization will act as a pressure buffer. When mastoid pneumatization is lacking, as happens in the otitis media syndrome, a pathological negative pressure will ensue.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Sadé J,Luntz M

doi

10.3109/00016489309135824

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

353-7

issue

3

eissn

0001-6489

issn

1651-2251

journal_volume

113

pub_type

杂志文章
  • The effect of crossed olivo-cochlear bundle stimulation on acoustic trauma.

    abstract::To investigate whether the crossed olivo-cochlear bundle (COCB) functions in a protective manner, albino guinea pigs were exposed to sounds of varying intensity (110-130 dB SPL, 3-30 min) with or without electric stimulation of COCB, and the threshold shifts of the compound action potential (CAP) were examined. A stat...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.1992.11665405

    authors: Takeyama M,Kusakari J,Nishikawa N,Wada T

    更新日期:1992-01-01 00:00:00

  • Juvenile nasopharyngeal angiofibroma. A report of eighteen cases.

    abstract::Juvenile nasopharyngeal angiofibroma is a disease afflicting mainly adolescent males. The lesion is benign but characterized by local aggressive growth. In advanced cases the tumour may extend intracranially. In this study 18 cases of juvenile nasopharyngeal angiofibroma were investigated. Tumour extension was assesse...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488809119456

    authors: Jacobsson M,Petruson B,Svendsen P,Berthelsen B

    更新日期:1988-01-01 00:00:00

  • Occurrence of tracheal carcinoma in Finland.

    abstract::During the period 1967-1985, 95 primary tracheal carcinomas occurred in Finland. The mean annual incidence rate was one per one million inhabitants, the male:female ratio being 7:3. There was a significant increase of the disease by increasing age with the exception of 70-79 years. The most common location was the low...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489109100772

    authors: Manninen MP,Antila PJ,Pukander JS,Karma PH

    更新日期:1991-01-01 00:00:00

  • Auditory brainstem evoked responses in the clinical evaluation and follow-up of insulin-dependent diabetic subjects.

    abstract::In the last few years the use of ABR in the dysmetabolic encephalopathies has aroused considerable interest. Even though brainstem involvement in these syndromes is not yet entirely understood, ABR techniques have provided new and important insights. We studied 60 insulin-dependent diabetic subjects, 29 females and 31...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:

    authors: Martini A,Comacchio F,Fedele D,Crepaldi G,Sala O

    更新日期:1987-05-01 00:00:00

  • Supernumerary outer hair cells arise external to the last row of sensory cells in the organ of corti.

    abstract::During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain obscure. When late embryonic or early postnatal rat organs of Corti we...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/000164801300043325

    authors: Lefebvr PP,Malgrange B,Thiry M,Breuskin I,Van De Water TR,Moonen G

    更新日期:2001-01-01 00:00:00

  • Effects of chronic exposure to electromagnetic waves on the auditory system.

    abstract:CONCLUSION:The results support that chronic electromagnetic field exposure may cause damage by leading to neuronal degeneration of the auditory system. OBJECTIVES:Numerous researches have been done about the risks of exposure to the electromagnetic fields that occur during the use of these devices, especially the effe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2015.1032434

    authors: Özgür A,Tümkaya L,Terzi S,Kalkan Y,Erdivanlı ÖÇ,Dursun E

    更新日期:2015-08-01 00:00:00

  • Convergence of central and peripheral signals on vestibular cells.

    abstract::Nerve and cortical input convergence patterns, representing the fore- and hindlimb, were studied in single cells located in the lateral vestibular nucleus of the cat. Deitersian cells responded with excitation to cortical stimulation with a latency ranging from 4 to 14 msec, while responses ranged from 9 to 12 msec to...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309130942

    authors: Azzena GB,Mameli O,Tolu E

    更新日期:1983-03-01 00:00:00

  • Middle ear transmission losses caused by tympanic membrane perforations in cats.

    abstract::Losses (determined by measuring microphonic responses) were essentially identical, regardless of whether produced by admittance of sound into the middle ear via perforations in the tympanic membrane (TM) or in the bulla. With SPLs monitored directly at the TM, losses increased at 12 dB/oct with inverse frequency for f...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487609119970

    authors: Tonndorf J,McArdle F,Kruger B

    更新日期:1976-03-01 00:00:00

  • Problems in alloplastic middle ear reconstruction.

    abstract::Alloplastic materials have been used in middle ear reconstruction since 1952. Biologically, biomaterials and specifically ceramics can be defined as being bioinert, bioactive or biodegradable; these terms being descriptive of the biochemical response provoked by the material in the host tissue. Various ceramics, carbo...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.1992.11665426

    authors: Blayney AW,Williams KR,Erre JP,Lesser TH,Portmann M

    更新日期:1992-01-01 00:00:00

  • The prevalence of hypothyroidism after treatment for laryngeal and hypopharyngeal carcinomas: are autoantibodies of influence?

    abstract:CONCLUSIONS:The incidence rate of hypothyroidism after treatment for laryngeal and hypopharyngeal cancer is high, especially after combination treatment. An association between hypothyroidism and autoantibodies was found. OBJECTIVES:The incidences of hypothyroidism and autoantibodies were assessed retrospectively in 1...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480600818096

    authors: Lo Galbo AM,de Bree R,Kuik DJ,Lips PT,Mary B,Von Blomberg E,Langendijk JA,Leemans CR

    更新日期:2007-03-01 00:00:00

  • High variability of perilymphatic entry of neutral molecules through the round window.

    abstract:OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480310001042

    authors: Chelikh L,Teixeira M,Martin C,Sterkers O,Ferrary E,Couloigner V

    更新日期:2003-01-01 00:00:00

  • The contribution of cranial-nerve nuclei to the short latency vestibular evoked potentials in cat.

    abstract::The object of this study was to assess the contributions of various cranial nerve nuclei to the short latency vestibular evoked potentials (VsEPs) in cat. The following nuclei were investigated: vestibular nuclei, and 3rd, 6th and 10th cranial nerve nuclei. In unilateral labyrinthectomized cats, suboccipital craniecto...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489509139277

    authors: Elidan J,Li G,Sohmer H

    更新日期:1995-03-01 00:00:00

  • Application of a rapid-prototyped temporal bone model for surgical planning.

    abstract:CONCLUSION:This 3D prototyped model constructed using a selective laser sintering method serves as a good material for surgical simulation of a malformed ear. OBJECTIVE:In order to perform surgery of the malformed ear, a thorough understanding of the anatomy of the ear is required, together with sufficient experience....

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480410016874

    authors: Suzuki M,Hagiwara A,Kawaguchi S,Ono H

    更新日期:2005-01-01 00:00:00

  • The effect of external stimuli on rat middle ear epithelium in culture. Extracellular carbon dioxide concentration.

    abstract::Serially cultivated rat middle ear epithelium was studied under exposure to various concentrations of carbon dioxide. Three experiments were performed exposing the epithelium to a gaseous environment containing 5 or 10% CO2 or to an atmosphere almost devoid of CO2. Oxygen was maintained constant at 20% and nitrogen wa...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489009125165

    authors: Lutgert HW,van Blitterswijk CA,Grote JJ

    更新日期:1990-05-01 00:00:00

  • Acute rhinosinusitis - are we forgetting the possibility of a dental origin? A retrospective study of 385 patients.

    abstract::Background: Odontogenic sinusitis (OS) is a common but underdiagnosed form of acute rhinosinusitis (ARS). OS carries no specific characteristics, but unilateral symptoms and certain microbiological as well as radiological findings indicate odontogenic origin. Aims/objectives: We studied the proportion of OS in ARS pat...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2019.1634837

    authors: Wuokko-Landén A,Blomgren K,Välimaa H

    更新日期:2019-09-01 00:00:00

  • Canal and otolith vestibulo-ocular reflexes to vertical and off vertical axis rotations in children learning to walk.

    abstract::In order to determine the characteristics of the vestibulo-ocular reflexes (VORs) as a function of age and posturo-motor development, a group of 26 normal children (6 to 25 months old) were tested at three different stages of posturo-motor control: prior to as well as during the first attempts to walk without support,...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:

    authors: Wiener-Vacher SR,Toupet F,Narcy P

    更新日期:1996-09-01 00:00:00

  • Induction of nitric oxide synthase activity in nucleus ambiguus motoneurons after injury to the rat recurrent laryngeal nerve.

    abstract::Recent studies have implicated nitric oxide (NO) in neuronal degeneration and plasticity in the motor nervous system. In the present study, we investigated the induction of nitric oxide synthase (NOS) in the motoneurons in the nucleus ambiguus (NA) after injury to the rat recurrent laryngeal nerve (RLN) using nicotina...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/000164800750001198

    authors: Bamba H,Uno T,Koike S,Shogaki K,Hisa Y

    更新日期:2000-03-01 00:00:00

  • The use of Preyer's reflex in evaluation of hearing in mice.

    abstract::Preyer's reflex, the elicitation of startle response to auditory stimuli, has been widely used for the evaluation of hearing in rodents and other animals. Surprisingly, however, the sensitivity and specificity of Preyer's reflex in the assessment of hearing has not been adequately studied. The aim of this study was to...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:

    authors: Jero J,Coling DE,Lalwani AK

    更新日期:2001-07-01 00:00:00

  • Investigation of resectability degree for adenoidal surgery in OSA children with the method of computational fluid dynamics.

    abstract:CONCLUSION:From aspect of fluid dynamics, expanding patients' nasopharyngeal coronal-sectional area to 48.3-54.7% of normal area will bring the airflow velocity back to normal in adenoidal hypertrophy children. It might provide a suggestion for adenoidectomy range selection and whether total resection is necessary. OB...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2016.1212266

    authors: Hu C,Han D,Zhou B,Zhang L,Li Y,Zang H,Li L

    更新日期:2017-01-01 00:00:00

  • Suppressive action of picrotoxin, a GABA antagonist, on labyrinthine spontaneous nystagmus and vertigo in man.

    abstract::There is evidence that GABA acts as the excitatory neurotransmitter at synapses between vestibular hair cells and the afferent fibres in the mammalian labyrinth. The question arose as to whether certain vestibular dysfunctions such as labyrinthine vertigo could be treated in patients by influencing the peripheral GABA...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488209130882

    authors: Ehrenberger K,Benkoe E,Felix D

    更新日期:1982-01-01 00:00:00

  • Congenital unilateral lower lip palsy.

    abstract::Thirty-nine cases of congenital facial asymmetry, in which one corner of the mouth does not dip downward symmetrically with the other, are presented. The author has termed this condition 'congenital unilateral lower lip palsy' (CULLP). CULLP was the most frequent condition in congenital facial anomalies seen in our cl...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487909137173

    authors: Kobayashi T

    更新日期:1979-01-01 00:00:00

  • Abducent nerve paralysis: first clinical sign of clivus metastasis from tonsillar carcinoma.

    abstract::It is known that 15-20% of oropharyngeal carcinomas develop distant metastases that involve most commonly lung, liver and bone. Clival metastasis from oropharyngeal squamous cell carcinoma has not been previously reported in the English literature. We describe the rare occurrence of clival metastasis from tonsillar ca...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480701687283

    authors: Marchese-Ragona R,Maria Ferraro S,Marioni G,Staffieri C,Manara R,Restivo DA,Staffieri A

    更新日期:2008-06-01 00:00:00

  • Expression of glycoconjugates in normal and Sjögren's syndrome labial glands.

    abstract::Glyconjugate expression in formalin-fixed, paraffin-embedded Sjögren's syndrome labial glands (nine cases) was compared with that in normal glands (12 samples) using a wide panel of lectins. Mucous cells expressed mainly mucous-type glycoproteins including sialyl, fucosyl, galactosyl and galactosaminosyl residues, and...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489709114217

    authors: Sidagis J,Ueno K,Wang ZH,Hanamure Y,Furuta S,Ohyama M

    更新日期:1997-11-01 00:00:00

  • Migration and differentiation of mouse embryonic stem cells transplanted into mature cochlea of rats with aminoglycoside-induced hearing loss.

    abstract:CONCLUSION:Mouse embryonic stem cells (ESCs) transplanted into the scala tympani are able to migrate in the cochlea of rats deafened with aminoglycoside and partly restore the structure of sensory epithelia of the inner ear. OBJECTIVES:To explore the migration and differentiation of enhanced green fluorescence protein...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2012.720029

    authors: Zhao LD,Li L,Wu N,Li DK,Ren LL,Guo WW,Sun JH,Liu HZ,Chen ZT,Xing GQ,Yang SM

    更新日期:2013-02-01 00:00:00

  • Sleep-related deglutition in patients with OSAHS under CPAP therapy.

    abstract:CONCLUSION:Continuous positive airway pressure (CPAP) therapy improved not only apnea-hypopnea during sleep and sleep structure but also sleep-related deglutition, especially respiratory phase patterns associated with deglutition. OBJECTIVES:Sleep-related deglutition and related respiratory phase patterns in patients ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2010.520166

    authors: Sato K,Umeno H,Chitose S,Nakashima T

    更新日期:2011-02-01 00:00:00

  • Evoked potentials from the auditory nerve following sinusoidal electrical stimulation of the cochlea: new possibilities for preoperative testing in cochlear-implant candidates?

    abstract::To predict the possible benefit of a cochlear implant to a patient, the clinician requires a reliable objective method to monitor the presence of surviving fibres in the 8th nerve. The subjective promontory test and the evaluation of electrically evoked brainstem potentials are not adequate. An electrical stimulus art...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489409126093

    authors: Hartmann R,Pfennigdorff T,Klinke R

    更新日期:1994-09-01 00:00:00

  • A six-month analysis of frontal sinus drainage pathway in patients with frontal sinusitis after balloon sinuplasty.

    abstract:BACKGROUND:The balloon catheter has been used for a decade to dilate paranasal sinus outflow tracts. The question is: how wide and how durable is the dilation of drainage pathways in patients in long-term observations after this procedure? OBJECTIVE:The objective of our study was to observe the changes occurring in th...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2017.1300941

    authors: Szczygielski K,Galusza B,Rapiejko P,Klopotek M,Jurkiewicz D

    更新日期:2017-09-01 00:00:00

  • Artifacts in eighth cranial nerve biopsy.

    abstract::The occurrence of artifactual morphological changes was investigated in human eighth nerve biopsies and corresponding changes were brought about in biopsies from rats by mechanical handling before fixation. At the very site of compression by a pair of forceps the biopsy stained lighter than in its immediate surroundin...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488009127111

    authors: Collan Y,Ylikoski J,Palva T,Selamaa R

    更新日期:1980-01-01 00:00:00

  • Histological reaction to polyimide films in the cochlea.

    abstract::The biocompatibility of commercially available polyimides was examined in relation to the sensory and neural structures of the cochlea. Thin films of four different polyimides were prepared as substrates for photolithographically produced scala tympani electrode arrays and implanted in 32 cat cochleae. Following at le...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488909127474

    authors: Haggerty HS,Lusted HS

    更新日期:1989-01-01 00:00:00

  • Strial dysfunction in a melanocyte deficient mutant rat (Ws/Ws rat).

    abstract::A homozygous mutant rat at the white spotting (Ws) locus showing a deficiency of melanocytes has recently been found (4, 5). The function and morphology of the inner ear of the Ws/Ws rat were examined by auditory brainstem response (ABR), endocochlear DC potential (EP), and electron microscopy. The mean ABR threshold ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489409126038

    authors: Kitamura K,Sakagami M,Umemoto M,Takeda N,Doi K,Kasugai T,Kitamura Y

    更新日期:1994-03-01 00:00:00