Abstract:
:In the last few years the use of ABR in the dysmetabolic encephalopathies has aroused considerable interest. Even though brainstem involvement in these syndromes is not yet entirely understood, ABR techniques have provided new and important insights. We studied 60 insulin-dependent diabetic subjects, 29 females and 31 males aged to 17 to 55 yrs, and observed ABR abnormalities in 28.2% of the cases. This impairment affects the I-V interval or central transmission time (CTT), which is considered the most reliable index of brainstem function. The ABR pattern was considered pathologic when the CTT was due 2DS as compared with a sex- and age-matched control. Follow-up studies performed on 20 of these subjects revealed no significant variation in the ABR tracing. This fact, together with the absence or correlation between ABR involvement and metabolic control and glycemia level during the test, could be attributed to a 'structural' damage of the brainstem tissue. In diabetics, we observed a significant correlation (p less than 0.05) between I-V interval shift and an EMG-proved reduction in motor conduction velocity (MCV) of the peroneal nerve. We also found a high incidence of ABR impairment (53%) in diabetics with cardiovascular autonomic failure.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Martini A,Comacchio F,Fedele D,Crepaldi G,Sala Osubject
Has Abstractpub_date
1987-05-01 00:00:00pages
620-7issue
5-6eissn
0001-6489issn
1651-2251journal_volume
103pub_type
杂志文章abstract::Acoustic rhinometry (AR) evaluates the geometry of the nasal cavity by measuring the minimum cross-sectional area (MCA) and nasal volume (V) by means of acoustic reflection. Understanding the normal and pathologic conditions of the internal nasal cavity using AR is important in the diagnosis of structural abnormalitie...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480152602311
更新日期:2001-10-01 00:00:00
abstract::Interleukins 6 (IL-6) and 12 (IL-12), and the chemoattractant chemokine RANTES were studied in ethmoidal mucosa, using reverse transcriptase polymerase chain reaction. The 49 patients had chronic sinusitis or nasal/paranasal polyposis, and some also allergy. To the best of our knowledge, this is the first study that d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137897
更新日期:1996-07-01 00:00:00
abstract::Following responses to constant velocity and sinusoidally oscillating movements of the whole visual environment were examined in normal subjects wearing blinkers to obscure central vision or subjected to a photo flash to induce a central scotoma, in patients with central scotomas of pathological origin and in one pati...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126455
更新日期:1979-05-01 00:00:00
abstract::The present paper investigates the hearing function in chronic otitis media vs. tympanoplasty in 41 patients with bilateral chronic otitis media, operated on unilaterally. The auditory evaluation was performed immediately before surgery and at a follow-up time varying from 1 to 14 years (mean = 5 years). Results were ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138410
更新日期:1991-01-01 00:00:00
abstract::Cells can die by two distinct pathways: apoptosis and necrosis. To explore whether intense noise can induce hair cell (HC) death via the apoptotic pathway, we systematically examined morphological changes in guinea pig cochlear HC nuclei stained with Hoechst 33342, a fluorescent dye specifically labelling the nuclear ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:CONCLUSIONS:The expression of phosphorylcholine (ChoP) in the surface of nontypeable Haemophilus influenzae (NTHi) is an important factor in the pathogenesis of persistent otitis media with effusion (OME) in humans. OBJECTIVES:Lipooligosaccharide (LOS) in NTHi undergoes phase variation in expression of the ChoP epitop...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802468195
更新日期:2009-08-01 00:00:00
abstract:CONCLUSION:Use of the Meniett pressure generator in patients with active Ménière's disease (MD) did not affect labyrinthine function. OBJECTIVE:To investigate whether application of the Meniett pressure generator in patients with active MD significantly affects their labyrinthine function. MATERIAL AND METHODS:We mea...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.1080/00016480500388869
更新日期:2006-03-01 00:00:00
abstract:INTRODUCTION:This study showed that short and long interval treatments achieved comparable success rates. There was no statistically significant difference in the rate of early and late recurrences between the two groups. Modified Epley maneuver can be applied in a short interval time with comparable success and recurr...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1252852
更新日期:2017-05-01 00:00:00
abstract:CONCLUSION:The midline electroneurography (ENoG) method might reflect total facial nerve degeneration. OBJECTIVE:We compared ENoG values in patients with facial palsy using two different methods, the midline method and five electroneurogram recordings, to reveal whether the ENoG value obtained with the midline method ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.743680
更新日期:2013-03-01 00:00:00
abstract::This paper describes an investigation performed to study the middle ear events ensuing from Staphylococcus aureus induced infection in the middle ear cavity of the rat. To obtain an evaluation at both the cell and the tissue level, scanning electron microscopy, transmission electron microscopy and histology were used....
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107560
更新日期:1984-09-01 00:00:00
abstract::The most common cause of seasonal allergic rhinitis in Japan is the Japanese cedar (JC). Recently, a pullulan-conjugated antigen (CS-560) has been developed to reduce adverse effects and to enhance the effect of JC-specific immunotherapy (IT). If the mechanism of IT can be fully elucidated and the treatment can be use...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.1080/00016480252775742
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:To identify the difference of surgical margin and recurrence status of early stage tongue carcinoma via wide excision in a single institution with and without free flap reconstruction. OBJECTIVE:Survey whether the reconstruction methods for early tongue cancer affects disease control, survival outcomes. ME...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1490030
更新日期:2018-10-01 00:00:00
abstract::A retrospective study was carried out on repeated audio-vestibular examinations in 53 patients with unilateral Meniere's disease, between the vertiginous spells. Most patients showed no change in the caloric response reduction of the afflicted ear in the subsequent tests compared with the first one. These patients had...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109133278
更新日期:1981-11-01 00:00:00
abstract::In 6 pigs a bronchoscopical resection of the tracheal mucosa was performed using CO2-laser on one side, and an electric high-frequency cutting loop (ECL) on the other. The pigs were sacrificed 3 months later. On macroscopic examination the tracheal mucosa appeared almost normal on the laser-resected side, while severe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127514
更新日期:1989-03-01 00:00:00
abstract:CONCLUSIONS:The distortion product otoacoustic emission (DPOAE) amplitudes in diabetics were significantly lower than those in controls when pure tone audiometry (PTA) was within normal limits, implying cochlear function impairment in the early stage of diabetes mellitus. Retrocochlear damage was suggested by elongated...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,meta分析,评审
doi:10.1080/00016489.2016.1223344
更新日期:2017-02-01 00:00:00
abstract::Background: In otosclerosis mixed hearing loss is the most frequent symptom and arises when the focus involves the stapes footplate. Surgeons usually prefer to wait a minimum air-bone gap of 25 - 35 dB before surgery.Objectives: To evaluate the outcome of microdrill stapedotomy for otosclerosis in patients with a preo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1764618
更新日期:2020-09-01 00:00:00
abstract::The occurrence of artifactual morphological changes was investigated in human eighth nerve biopsies and corresponding changes were brought about in biopsies from rats by mechanical handling before fixation. At the very site of compression by a pair of forceps the biopsy stained lighter than in its immediate surroundin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127111
更新日期:1980-01-01 00:00:00
abstract:CONCLUSION:The possible roles of CD44st, CD44v5 and CD44v6 in the prognosis of head and neck cancer deserve further elucidation and evaluation with long-term patient follow-up. OBJECTIVE:Standard CD44 (CD44st), CD44 variant 5 (CD44v5) and CD44 variant 6 (CD44v6) are expressed in human malignant cells and tissues. The ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510026971
更新日期:2005-04-01 00:00:00
abstract::Substance P has been proved an important neurotransmitter and neuromodulator, serving not only as an excitatory transmitter of the first afferent synapse of pain pathways but as a valuable neuromodulator in the primary cortical areas of sensosensorial integration. In the human acoustic cortex, substance P has been fou...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127525
更新日期:1989-05-01 00:00:00
abstract::During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain obscure. When late embryonic or early postnatal rat organs of Corti we...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300043325
更新日期:2001-01-01 00:00:00
abstract::Background: Odontogenic sinusitis (OS) is a common but underdiagnosed form of acute rhinosinusitis (ARS). OS carries no specific characteristics, but unilateral symptoms and certain microbiological as well as radiological findings indicate odontogenic origin. Aims/objectives: We studied the proportion of OS in ARS pat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1634837
更新日期:2019-09-01 00:00:00
abstract:CONCLUSIONS:In order to confirm these preliminary results, a prospective double-blind study has been instituted in Padova University ENT Section to compare the efficacy of sulphurous-arsenical-ferruginous thermal water nasal irrigations vs isotonic sodium chloride solution nasal irrigations after functional endoscopic ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600951525
更新日期:2007-06-01 00:00:00
abstract::Thirty-two patients affected by idiopathic benign paroxysmal positional vertigo (BPPV) of the posterior semicircular canal were studied before, 3 days and I month after a resolutive Semont manoeuvre by means of dynamic posturography. The overall postural control in BPPV patients was shown to be impaired, as demonstrat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850183340
更新日期:1998-06-01 00:00:00
abstract::Explants of stria vascularis and spiral ligament of guinea pig cochlea were kept in primary culture. On the explant, proliferating marginal cells advanced by 15 microns/day, suggesting that in vivo defects of the strial epithelium can be covered by new marginal cells. The marginal cells growing in the cell culture dis...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137471
更新日期:1992-09-01 00:00:00
abstract::Abstract Usage of the Vibrant Soundbridge (VSB) with round window (RW)-Coupler placement at the RW has been shown to successfully treat mixed hearing loss. Coupling between the VSB's floating mass transducer (FMT) and the RW membrane is difficult in the case of sclerosis in the RW and drilling down the bony lip unti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.649492
更新日期:2012-06-01 00:00:00
abstract:CONCLUSIONS:We describe a Japanese family with high-frequency sensorineural hearing loss (SNHL) harboring a c.211delC mutation in the KCNQ4 gene. Families showing progressive high-frequency SNHL should be investigated for mutations in the KCNQ4 gene. OBJECTIVE:To determine the responsible deafness gene in a Japanese f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.890740
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:Mutations in the fibrillar collagen genes COL11A1 and COL11A2 can cause sensorineural hearing loss associated with Stickler syndrome. There is a correlation of hearing loss severity, onset, progression and affected frequencies with the underlying mutated collagen gene. We sought to determine whether differenc...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016162
更新日期:2004-04-01 00:00:00
abstract::The author has performed clinical and follow-up studies of 80 acromegalic patients treated by transanthro-sphenoidal removal of the pituitary adenoma. Heredity for acromegaly or gigantism was recorded in 3.8% of the patients and other hereditary factors in 13.8%. Head trauma, meningitis or encephalitis was recorded in...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609120891
更新日期:1976-09-01 00:00:00
abstract::As a continuation of our previous work, where we have demonstrated that in chronic otitis media the picture in the submucosa-bone marginal zone is dominated by capillary proliferation and occurrence of a mononuclear, histiocyte-like cell containing lysosome-like cytoplasmatic bodies, we now report the presence of cons...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509124704
更新日期:1975-05-01 00:00:00
abstract::We examined the mucosa of 50 rat middle ears in an experimental model of acute otitis media, in order to obtain information on the mechanisms of polyp formation. The right middle ear of 25 rats was inoculated with type 3 pneumococci, and the left ear served as a control. The animals were killed, the middle ear bulla r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509133351
更新日期:1995-01-01 00:00:00