Role of margin status in recurrence after CO2 laser endoscopic resection of early glottic cancer.

abstract：CONCLUSIONS:Klotho protein content decreases with increasing age, which weakens resistance to oxidative stress, resulting in induced cell death as well as modulating endolymph fluid homeostasis. Down-regulation of klotho also leads to down-regulation of TRPV5 and TRPV6, resulting in modified Ca(2+) homeostasis in the i...

journal_title：Acta oto-laryngologica

authors： Takumida M,Ishibashi T,Hamamoto T,Hirakawa K,Anniko M

更新日期：2009-12-01 00:00:00

abstract：:The tonsils are mucosa-associated lymphoid organs. Several details regarding their normal function and pathological alteration are still unknown. In this review the relationship of the tonsils to similar lymphoid organs is discussed, the possibilities of antigen uptake (M cells and micropores of the crypt epithelium) ...

journal_title：Acta oto-laryngologica

authors： Surján L Jr

更新日期：1987-05-01 00:00:00

abstract：CONCLUSIONS:Patients with sudden hearing loss and dizziness after barotrauma should be suspected of barotraumatic perilymph fistula (PLF). Early surgical repair of PLF showed better hearing outcomes. Therefore, diagnostic criteria should help surgical indications of barotraumatic PLF. OBJECTIVES:The aim of this study ...

journal_title：Acta oto-laryngologica

authors： Choi JE,Moon IJ,Kim H,Lee K,Cho YS,Chung WH

更新日期：2017-01-01 00:00:00

abstract：:Acid base balance changes were observed during 72 h following bilateral nasal obstruction in rats. Mouth breathing caused acute respiratory acidosis and marked aerophagia, leading to spontaneous death of the experimental animal 80 to 90 h postoperatively. Stenotic oropharyngeal airway, due to palatal-epiglottic approx...

journal_title：Acta oto-laryngologica

authors： Kalogjera L,Pegan B,Petric V

更新日期：1991-01-01 00:00:00

abstract：:Organophosphorus compounds in the form of insecticides are in widespread use and have recently attracted considerable interest as environmentally toxic agents. As little is known about the effect of environmental toxins on the tubal function in the ear, we studied the middle ear pressure necessary to force the eustach...

journal_title：Acta oto-laryngologica

authors： Bergler W,Juncker C,Petroianu G,Keilmann A,Hörmann K

更新日期：1995-07-01 00:00:00

abstract：:An impaired ostial function may be of importance in the pathogenesis of the maxillary sinus empyema due to changes of the antral gas composition. Oxygen is usually not demonstrable in purulent sinus secretion while carbon dioxide accumulates. In vitro, pneumococci were able to create a similar gas environment, provide...

journal_title：Acta oto-laryngologica

authors： Carenfelt C,Lundberg C

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:The most crucial clinical problem of Eosinophilic Otitis Media (EOM) is sensorineural hearing loss. A previous report revealed that repeated antigen stimulation of middle ear causes eosinophilic inflammation not only in the middle ear but also in the inner ear. OBJECTIVE:The purpose of the present study was...

journal_title：Acta oto-laryngologica

authors： Kudo N,Matsubara A,Nishizawa H,Miura T

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Temperature-controlled radiofrequency volumetric tissue reduction (RFVTR) is a minimally invasive technique used in the treatment of the tongue base, soft palate and turbinates. Complications seem to be rare, but the scope of previous studies was often limited by the small number of patients included. The aim...

journal_title：Acta oto-laryngologica

authors： Stuck BA,Starzak K,Verse T,Hörmann K,Maurer JT

更新日期：2003-05-01 00:00:00

abstract：:Glyconjugate expression in formalin-fixed, paraffin-embedded Sjögren's syndrome labial glands (nine cases) was compared with that in normal glands (12 samples) using a wide panel of lectins. Mucous cells expressed mainly mucous-type glycoproteins including sialyl, fucosyl, galactosyl and galactosaminosyl residues, and...

journal_title：Acta oto-laryngologica

authors： Sidagis J,Ueno K,Wang ZH,Hanamure Y,Furuta S,Ohyama M

更新日期：1997-11-01 00:00:00

abstract：CONCLUSION:Moxifloxacin was generally well tolerated and highly effective in the treatment of acute bacterial rhinosinusitis (ABS). The incidence of adverse events (AEs) and adverse drug reactions (ADRs) was low. The effectiveness, safety, and tolerability information collected in this study confirm the clinical safety...

journal_title：Acta oto-laryngologica

authors： Zhou B,Jiang X,Zhai L,Xiao S,Wang J,Xiao G,Ruan B,Liang C,Ye Q,Hu B,Wang H

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To investigate whether the extent of expression of hyaluronan (HA) and epidermal growth factor receptor (EGFR) in squamous cell carcinoma of the mobile tongue can predict the risk of cervical metastasis and survival. STUDY DESIGN:Retrospective histopathologic study. METHODS:Surgical specimens from 64 patien...

journal_title：Acta oto-laryngologica

authors： Lindell Jonsson E,Nylander K,Hallén L,Laurell G

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:This study was conducted to demonstrate the safety and efficacy of the Otologics Middle Ear Transducer (MET) Ossicular Stimulator and, in particular, to compare the audiologic benefits of this novel form of electromechanical stimulation with those of conventional acoustical amplification. MATERIAL AND METHO...

journal_title：Acta oto-laryngologica

authors： Jenkins HA,Niparko JK,Slattery WH,Neely JG,Fredrickson JM

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Combination therapy consisting of a platinum agent, 5-fluorouracil and cetuximab (EXTREME regimen) is recommended for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M-SCCHN). However, it is advisable to use platinum-free regimens as first-line therapy in patients resistant to platinu...

journal_title：Acta oto-laryngologica

authors： Sato H,Tsukahara K,Okamoto I,Katsube Y,Shimizu A,Kondo T,Hanyu K,Fushimi C,Okada T,Miura K

更新日期：2019-02-01 00:00:00

abstract：:The author has performed clinical and follow-up studies of 80 acromegalic patients treated by transanthro-sphenoidal removal of the pituitary adenoma. Heredity for acromegaly or gigantism was recorded in 3.8% of the patients and other hereditary factors in 13.8%. Head trauma, meningitis or encephalitis was recorded in...

journal_title：Acta oto-laryngologica

authors： Kinnman JE

更新日期：1976-09-01 00:00:00

abstract：CONCLUSIONS:Sensorineural hearing loss must be considered within the clinical picture of systemic lupus erythematosus. The results confirm the usefulness of extended high-frequency audiometry in the audiologic testing of these patients, enabling the possibility of modifying or applying a preventive treatment for a poss...

journal_title：Acta oto-laryngologica

authors： Lasso de la Vega M,Villarreal IM,López Moya J,García-Berrocal JR

更新日期：2017-02-01 00:00:00

abstract：:This report shows the changes that occurred in consecutive audiograms of a patient who underwent chemotherapy and radiotherapy for nasopharyngeal cancer and the histopathological examination of the temporal bones. Both conductive and sensorineural hearing loss developed, but followed different modes of progression. In...

journal_title：Acta oto-laryngologica

authors： Asenov DR,Kaga K,Tsuzuku T

更新日期：2007-10-01 00:00:00

abstract：CONCLUSION:Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study. Resectability of the tumor seems to be major prognostic factor of temporal bone SCC. OBJECTIVE:Prognostic f...

journal_title：Acta oto-laryngologica

authors： Ito M,Hatano M,Yoshizaki T

更新日期：2009-11-01 00:00:00

abstract：:Background: Chronic rhinosinusitis (CRS) is an inflammatory disease of the nose and the paranasal sinuses, often associated with an infection by Staphylococcus aureus (S. aureus). Disturbance in the function of ion channels is regarded as an etiological factor for pathogenesis of CRS. Aims: The study aims to measure t...

journal_title：Acta oto-laryngologica

authors： Saber A,Nakka SS,Hussain R,Hugosson S

更新日期：2019-07-01 00:00:00

abstract：:Primary afferent projections from singular parts of the vestibular labyrinth were studied in the guinea pig. The posterior ampullary nerve, the common trunk of the anterior and lateral ampullary nerves, as well as fibers innervating the macula sacculi or the macula utriculi were traced with crystals of horseradish per...

journal_title：Acta oto-laryngologica

authors： Gstoettner W,Burian M,Cartellieri M

更新日期：1992-01-01 00:00:00

abstract：:683 tumour fragments from 63 head and neck carcinoma patients were cultured in vitro. Two laryngeal carcinomas and two salivary gland carcinomas were established into permanent cell lines. Malignancy of these cultured cells was proved by cloning, by chromosomal analysis and by transplantation into athymic (nu/nu) mice...

journal_title：Acta oto-laryngologica

authors： Zenner HP,Herrmann IF,Bremer W,Stahl-Maugé C

更新日期：1983-03-01 00:00:00

abstract：:IL2Rs, in the presence of IL2, mediate activation and proliferation of human normal lymphocytes and modulate functional changes of some human leukocytic malignancies. IL2Rs have been demonstrated also on human neoplastic and fetal non-hematologic cells in vitro, although their functional role has not been described. W...

journal_title：Acta oto-laryngologica

authors： Cortesina G,Sacchi M,Galeazzi E,Johnson JT,Whiteside TL

更新日期：1992-01-01 00:00:00

abstract：:The maintenance of upright stance in humans requires the integrative evaluation of vestibular, visual, and proprioceptive information. Recent experiments prove the existence of fast vestibulo-spinal reactions in humans. Their physiological significance for the compensation of sudden external displacements of the body ...

journal_title：Acta oto-laryngologica

authors： Dichgans J,Diener HC

更新日期：1989-05-01 00:00:00

abstract：:Detection of immune complexes (ICs) of IgG, IgM, or IgA isotypes in middle ear effusions (MEEs) by the solid-phase anti-C3 ELISA and cytologic analyses of MEEs were done in 245 patients with otitis media with effusion (OME). In 320 ears, the clinical classification was acute, 10.3%; subacute, 16.6%; chronic, 73.1%. In...

journal_title：Acta oto-laryngologica

authors： Yamanaka N,Somekawa Y,Suzuki T,Kataura A

更新日期：1987-11-01 00:00:00

abstract：CONCLUSION:Our results indicate that siRNA E6 and/or E7 may have potential as a gene-specific therapy for human papillomavirus (HPV) type 16 (HPV16)-related squamous cell carcinoma of the head and neck (HNSCC). OBJECTIVES:To evaluate the effectiveness of siRNA targeting E6 and/or E7 on the in vitro and in vivo growth ...

journal_title：Acta oto-laryngologica

authors： Adhim Z,Otsuki N,Kitamoto J,Morishita N,Kawabata M,Shirakawa T,Nibu K

更新日期：2013-07-01 00:00:00

abstract：:A delayed conditioning paradigm was employed to condition the stapedius muscle. While many previous attempts have failed using loud sound as the unconditioned stimulus(UCS), this paper presents evidence of successful conditioning of this muscle when the unconditioned stimulus was a mild electrocutaneous stimulation of...

journal_title：Acta oto-laryngologica

authors： Yonovitz A

更新日期：1976-07-01 00:00:00

abstract：:The blowing of chilled (14 degrees C) air into the external auditory canal (EAC) resulted in a profuse middle ear fluid production. The stimulation caused marked changes in the pars flaccida of the tympanic membrane. A slight vasodilatation was noted in the oedematous loose connective tissue layer of the pars flaccida...

journal_title：Acta oto-laryngologica

authors： Goldie P,Hellström S

更新日期：1986-09-01 00:00:00

abstract：:The nasal airways of 94 healthy term infants (37-42 weeks gestational age) were examined by continuous wide-band noise acoustic rhinometry under standardized conditions on the second or third day postpartum. Validation of the flexible infant probe on tubular plastic models with dimensions similar to the nasal cavity o...

journal_title：Acta oto-laryngologica

authors： Djupesland PG,Lyholm B

更新日期：1997-05-01 00:00:00

abstract：:In a double-blind crossover trial, 24 patients with perennial rhinitis have been treated with 2% disodium cromoglycate (DSCG) nasal spray. 15 patients preferred DSCG to placebo, 9 patients showed no preference. Analysis of the diary cards showed a significant preference of DSCG in the group which received placebo firs...

journal_title：Acta oto-laryngologica

authors： Balle V,Illum P

更新日期：1977-09-01 00:00:00

abstract：:Paclitaxel (Taxol) is an antimicrotubular agent which blocks the cells in the G2/M phase of the cell cycle. Because of this mechanism it is presumed that this drug could function as a radiation sensitizer. The cytotoxic and genotoxic effects of paclitaxel and a combination of paclitaxel and radiation were studied in t...

journal_title：Acta oto-laryngologica

authors： Preisler VK,Stopper H,Schindler D,Friedl R,Pfreundner L,Hoppe F,Hagen R

更新日期：1998-07-01 00:00:00

abstract：CONCLUSION:Selected patients with Meniere's disease (MD) show an improvement of disability from vertigo after transtympanic ventilation tube insertion, although an effect on vestibular function is not seen if ipsilateral middle ear pressure lower than -50 daPa is used as a selection criterion. OBJECTIVES:Transtympanic...

journal_title：Acta oto-laryngologica

authors： Park JJ,Chen YS,Westhofen M

更新日期：2009-12-01 00:00:00