Abstract:
:Two hundred Malaysian patients representing 227 ears with previously untreated cholesteatoma disease were analysed retrospectively in terms of i) type of disease, i.e. primary acquired attic defect or posterior superior retraction pocket and secondary acquired type cholesteatoma; ii) positive history of previous middle ear effusion, atelectasis or grommet insertion; and iii) likelihood of complications as initial presenting feature. The high 47.1% incidence of secondary acquired cholesteatoma disease in our patients contrasts with the predominance of primary acquired cholesteatoma in the Caucasian patient. Correlation of these two disease types with a positive history showed a significant positive association between the primary acquired group and a positive history; and conversely a significant negative association for the secondary acquired type. This supports a role for the retraction theory in primary acquired cholesteatoma but negates this theory in secondary acquired cholesteatoma. Secondary acquired cholesteatoma had a significantly higher (35.5%) complication rate against 15.8% in the primary acquired type (p = 0.001). This fact together with a 47.1% incidence of secondary acquired disease, low otolaryngologist population ratio and patient attitudes to disease account for the high total complication rate of 27.3%.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Lee STdoi
10.3109/00016489109138380subject
Has Abstractpub_date
1991-01-01 00:00:00pages
536-41issue
3eissn
0001-6489issn
1651-2251journal_volume
111pub_type
杂志文章abstract:CONCLUSIONS:Local administration of MP delivered by the C/GP-MP-hydrogel can improve the recovery of facial nerve following crush injury. The findings suggested that locally injected MP delivered by C/GP-hydrogel might be a promising treatment for facial nerve damage. OBJECTIVES:In this study, the aim is to assess the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract::The purpose of this study was to establish whether lactoferrin (hLf) attached to Streptococcus pyogenes, one causative agent of acute pharyngotonsillitis (AT), during the course of the disease. Bacterial samples were obtained from the tonsillar surfaces of 7 patients (6 females, 1 male; median age 26 years; range 16-5...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract::The effects of two simulated hearing impairments (presbyacusis) on speech perception were investigated in two groups of normally hearing subjects (30 and 48 subjects, respectively). Eight patients with presbyacusis with similar hearing impairment to those in the latter simulation served as the clinical material. Word ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000991
更新日期:2000-03-01 00:00:00
abstract::Acoustic rhinometry (AR) evaluates the geometry of the nasal cavity by measuring the minimum cross-sectional area (MCA) and nasal volume (V) by means of acoustic reflection. Understanding the normal and pathologic conditions of the internal nasal cavity using AR is important in the diagnosis of structural abnormalitie...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480152602311
更新日期:2001-10-01 00:00:00
abstract::Eleven patients, who had symptoms of blocking nose in relation to exposure to airway irritants in their work environment, and 11 control subjects recorded nasal and bronchial peak expiratory flow rates (PEFRN and PEFRB) during a working week. In contrast to the control subjects the patients demonstrated a pattern of g...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:Combination therapy consisting of a platinum agent, 5-fluorouracil and cetuximab (EXTREME regimen) is recommended for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M-SCCHN). However, it is advisable to use platinum-free regimens as first-line therapy in patients resistant to platinu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2018.1551623
更新日期:2019-02-01 00:00:00
abstract::The aim of this study was to determine the basic properties of the 2f2-f1 distortion product otoacoustic emissions (DPOEs) in 36 normally hearing subjects and to compare their characteristics with those of the 2f1-f2 DPOEs. The influence of stimulation parameters on 2f2-f1 DPOE behaviour was examined: i) stimulation l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850155099
更新日期:1998-01-01 00:00:00
abstract::Glycerol (2 g/kg body weight), or 0.15 M NaCl for control animals, was administered to rats by i.v. injection. The dose was chosen in order to obtain an osmolarity increase in plasma of about 15 mosm/l 1 h after the glycerol administration, an increase which is similar to that observed in the human glycerol dehydratio...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137887
更新日期:1996-07-01 00:00:00
abstract::The sound conduction method for measurement of the Eustachian tube opening has been studied and modifications made in the test procedure to increase its easy performance and reliability. By holding the sound source near to the nostril, mounting the microphone into a circumaural ear defender and by feeding the output o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809124724
更新日期:1978-07-01 00:00:00
abstract:CONCLUSION:The risk of operation-requiring postoperative bleeding after abscess tonsillectomy is no different from the risk after elective tonsillectomy. However, the risk is higher for older than for younger patients, both for the whole cohort and for tonsillectomy à chaud. OBJECTIVE:The objective of the present stud...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.660545
更新日期:2012-07-01 00:00:00
abstract::We evaluated the vestibulo-ocular reflex (VOR) in 50 normal human subjects, uniformly distributed in age 20-59 years, and evenly distributed in sex by decade, using sinusoidal rotation over the frequency range of 0.005 to 1.0 Hz and three peak amplitudes of 25, 50, and 100 deg/sec. Age variations. The gain magnitude o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107563
更新日期:1984-09-01 00:00:00
abstract:CONCLUSION:The midline electroneurography (ENoG) method might reflect total facial nerve degeneration. OBJECTIVE:We compared ENoG values in patients with facial palsy using two different methods, the midline method and five electroneurogram recordings, to reveal whether the ENoG value obtained with the midline method ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.743680
更新日期:2013-03-01 00:00:00
abstract::Dynamic range (DR) of cochlear implant electrodes and speech recognition scores (SRS) were chronologically studied in 23 post-lingually deaf subjects over a period of one year. DR significantly increased over one year (ANOVA, p = 0.03). When DR was compared among three groups of electrodes which were located in the in...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137829
更新日期:1996-03-01 00:00:00
abstract:CONCLUSION:The present study demonstrated the robustness of VEMP testing with toneburst stimuli, since it is hardly affected by head position, i.e. base or tonic excitation levels of the saccule and inferior vestibular nerve. However, the small but highly significant difference found in latency should not be neglected:...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600740597
更新日期:2007-01-01 00:00:00
abstract::Little is known about the physiologic regulation of the vestibular end organ blood flow. The purpose of the current study was to examine posterior semicircular canal ampulla blood flow in addition to systemic factors during intravenous infusions of calcitonin-gene related peptide (CGRP), a factor involved in the tonic...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709114207
更新日期:1997-11-01 00:00:00
abstract::Intense sound stimulation may result in excessive glutamate release from the inner hair cells, resulting in binding to the postsynaptic glutamate receptors and leading to neuronal degeneration and functional impairment. In this study we investigated the therapeutic effect and time window of caroverine, an N-methyl-D-a...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310000638
更新日期:2003-10-01 00:00:00
abstract:CONCLUSION:Mouse embryonic stem cells (ESCs) transplanted into the scala tympani are able to migrate in the cochlea of rats deafened with aminoglycoside and partly restore the structure of sensory epithelia of the inner ear. OBJECTIVES:To explore the migration and differentiation of enhanced green fluorescence protein...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.720029
更新日期:2013-02-01 00:00:00
abstract::The gas nitric oxide (NO) is present in high concentrations in human nasal airways. Since NO is known to inhibit the growth of bacteria and viruses, it has been suggested that airborne NO represents the first line of defence against pathogens in the upper airways. Low nasal NO levels have been reported previously in p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000676
更新日期:2000-03-01 00:00:00
abstract:CONCLUSION:The technology of stimulation rates between 1500 and 5000 pulses per second per channel (pps/ch) brings a benefit for all users. However, the fastest possible rate does not necessarily lead to best hearing performance in each individual subject. Individual optimization of stimulation rate is recommended. OB...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480902971239
更新日期:2010-01-01 00:00:00
abstract::Voluntary control of the human vestibulo-ocular reflex with and without visual targets was investigated. Subjects were rotated sinusoidally from 0.1 to 1.0 Hz using d.c. electro-oculography to record eye position. The ratio of eye to head movement, or gain, of the vestibulo-ocular reflex was measured. When subjects we...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609107490
更新日期:1976-05-01 00:00:00
abstract::The effects of transdermally administered scopolamine (TTS-scopolamine) (release rate 5 micrograms/h, one and two patches) and dimenhydrinate (100 mg) on caloric, angular acceleration induced and optokinetic nystagmus were examined in 16 volunteers in a randomized double-blind study. All drugs induced a statistically ...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016488509182266
更新日期:1985-05-01 00:00:00
abstract::Background: Odontogenic sinusitis (OS) is a common but underdiagnosed form of acute rhinosinusitis (ARS). OS carries no specific characteristics, but unilateral symptoms and certain microbiological as well as radiological findings indicate odontogenic origin. Aims/objectives: We studied the proportion of OS in ARS pat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1634837
更新日期:2019-09-01 00:00:00
abstract::The vestibulo-ocular reflex (VOR) of the alert rhesus monkey was studied using rotational acceleration in the horizontal plane. Both sinusoidal and pseudorandom binary sequence (PRBS) stimuli were used to perform parameters. Results from sinusoidal studies over the frequency range 0.01 to 1.28 Hz, with stimulus amplit...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130856
更新日期:1982-01-01 00:00:00
abstract:CONCLUSION:The improved biocompatibility of Bioverit II coated with a nanostructured surface shows promising qualities for use in human reconstructive middle ear surgery. In the case of chitosan-hydroxyapatite composite prostheses, further investigations regarding composition of the material, degree of purity and desig...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480601053032
更新日期:2007-08-01 00:00:00
abstract::The efferent cochlear system, composed of both ipsi- and contralateral bundles, runs along with the vestibular nerve and may serve as protection for the inner ear. Sectioning of the vestibular nerve could thus create an experimental model for further in-depth study of such a protective role. A personal surgical approa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950181602
更新日期:1999-03-01 00:00:00
abstract:CONCLUSION:The study showed that surgery in the maxillary sinus can affect its development. OBJECTIVE:To quantitatively evaluate the long-term impact of sinus surgery on its development in the rabbit. MATERIALS AND METHODS:This was an experimental study performed at an academic tertiary medical center using 20 4-week...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701596039
更新日期:2008-05-01 00:00:00
abstract::Vascularization between vestibular schwannomas and the adjacent eighth cranial nerve was examined in order to elucidate the angiogenic effect of these tumours. Specimens from 12 patients were examined by light microscopy and immunohistochemistry (series 1), while specimens from another 17 patients were examined by lig...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137712
更新日期:1996-01-01 00:00:00
abstract::Enzymatic tracer techniques to study normal and pathologic strial capillary transport pose various problems. The use of electron opaque tracers can circumvent many of these problems. Iron dextran (mol. diam 20--70 A) and ferritin (mol. diam 110 A) were injected intravenously and the mice sacrificed at intervals of 1/2...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127103
更新日期:1980-01-01 00:00:00
abstract:CONCLUSION:The external neck brace (ENB) is a new concept in the improvement of peristomal fixation of an automatic stoma valve (ASV), which was evaluated with a new imaging method. The addition of the ENB to the Flexiderm (FLD) and Xtrabase (XB) adhesives significantly reduced absolute mean differences between the spe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903426600
更新日期:2010-07-01 00:00:00
abstract:CONCLUSION:The endoscopic transnasal approach with IGS is a safe and effective technique, allowing completely resection of JPOF, with minimal morbidity and recurrence. OBJECTIVES:JPOF is a benign but locally aggressive fibro-osseous lesion. This study presents a series of JPOF cases, involving anterior skull base and ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1276302
更新日期:2017-07-01 00:00:00