Abstract:
:Dynamic range (DR) of cochlear implant electrodes and speech recognition scores (SRS) were chronologically studied in 23 post-lingually deaf subjects over a period of one year. DR significantly increased over one year (ANOVA, p = 0.03). When DR was compared among three groups of electrodes which were located in the inferior, ascending and superior segments of the cochlear basal turn, that in the superior segment showed the largest increase (p = 0.001), followed by those in the ascending and inferior segments. Vowel and consonant recognition scores with auditory cue were best 6 months after operation and were maintained at the level for one year. Although the time course of improvement differed between DR and SRS, a significant positive correlation was observed at 12 months after operation. Improvement of SRS could be a result of a DR increase in the superior segment of the cochlea, which should convey pitch information over the mid-frequency region.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Kubo T,Iwaki T,Ohkusa M,Doi K,Uno A,Yamamoto K,Fujii Kdoi
10.3109/00016489609137829subject
Has Abstractpub_date
1996-03-01 00:00:00pages
224-7issue
2eissn
0001-6489issn
1651-2251journal_volume
116pub_type
杂志文章abstract:CONCLUSIONS:The critical stage for cochlear gene regulation in the embryo is E49-E56. These data provide a valuable resource to help elucidate gene regulation in cochlear development and will benefit ear-related studies, especially those that focus on gene and stem cell therapies in hearing loss. OBJECTIVES:To investi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1341641
更新日期:2017-11-01 00:00:00
abstract::A prospective study was carried out to objectively quantificate the most important predictive factors in idiopathic facial paralysis (Bell's palsy). Stepwise discriminant analysis was applied to data prospectively obtained from 570 patients with Bell's palsy treated at the ENT Department of La Paz Hospital between Jan...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809106436
更新日期:1988-09-01 00:00:00
abstract::Blood circulation in the cochlear lateral wall after exposure to a non-physiological level of sound (120-125 dB SPL, 3 h) was investigated immunohistologically. Kanamycin (KM), which was expected to function as a tracer of blood flow, was administered to guinea pigs 5 min to 21 h after sound termination. At 5-30 min, ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137358
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The role of endonasal endoscopic surgery and radiotherapy in the treatment of skull base chordomas remains unclear. OBJECTIVE:We investigated the effect of endonasal endoscopic surgery and radiotherapy as treatment for skull base chordomas. METHOD:We investigated 46 patients (2006-2018) treated at the Affi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1748225
更新日期:2020-09-01 00:00:00
abstract:CONCLUSION:The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests a compensation for the decreased amount of saliva secretion associated with age progression. OBJECTIVE:To investigate the change in aquaporin-1 (AQP1) and aquaporin-5 (AQP5) expression in the sa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1165353
更新日期:2016-09-01 00:00:00
abstract:CONCLUSION:Candidates for hearing preservation cochlear implant (CI) surgery can be divided into: those who benefit from electrical complement (EC) to remaining hearing and don't require additional amplification, those using a combined electric-acoustic stimulation (EAS) and those with the least amount of residual hear...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903567189
更新日期:2010-08-01 00:00:00
abstract::The subjective visual horizontal (SVH) was measured by means of a small, rotatable, luminous line in darkness in the upright head and body position and at 10, 20 and 30 degrees of tilt to the right and left before, and repeatedly during a follow-up period of 1 year after intratympanic gentamicin instillations in 12 pa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850154595
更新日期:1998-07-01 00:00:00
abstract::The present paper presents monopolar recording of facial nerve antidromic potentials as an alternative technique to facial electromyography for the continuous monitoring of the facial nerve during acoustic neuroma surgery. The investigation involved 22 patients undergoing acoustic neuroma surgery via a retrosigmoid ap...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709113457
更新日期:1997-09-01 00:00:00
abstract:CONCLUSIONS:Analysis of the complete mtDNA genome and X-linkage of this five-generation Chinese family revealed that the 1555A > G mutation may lead to deafness. OBJECTIVES:Mutations in mitochondrial DNA (mtDNA) have been found to be associated with sensorineural hearing loss. However, the variable clinical phenotype ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.575794
更新日期:2011-09-01 00:00:00
abstract::Laryngoscopy in cases of sulcus vocalis reveals bowed vocal folds, resulting in a spindle-shaped chink with glottal incompetence. The anatomic and functional problems and resulting incomplete glottal closure during phonation lead to the presenting symptoms of breathy hoarseness, decrease in maximum phonation time (MPT...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489.2014.999873
更新日期:2015-06-01 00:00:00
abstract:CONCLUSION:Systemic application of human mesenchymal stem cells (hMSCs) may be another effective tool for stem cell supply to the inner ear. OBJECTIVES:Most researchers have used local application to provide the inner ear with stem cells. In spite of their efficacy, these methods can potentially cause irreversible dam...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.660731
更新日期:2012-06-01 00:00:00
abstract::The efficacy of diclofenac suppositories was estimated in a two-centre, double-blind, placebo-controlled study comprising 97 patients (47 in the diclofenac group and 50 in the placebo group). The series from the two centres and patients in the two treatment groups were comparable. Immediately postoperatively, the pati...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016488409107553
更新日期:1984-07-01 00:00:00
abstract::In 82 patients with acute tonsillitis studied, beta-hemolytic group A streptococci were isolated from 30 (37%), and group C or G streptococci from 12 (15%). In the 40 patients with non-streptococcal tonsillitis there was a significantly higher isolation rate of pneumococci, H. influenzae and/or B. catarrhalis, as comp...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107339
更新日期:1987-09-01 00:00:00
abstract:CONCLUSION:Endoscopic cauterization of the sphenopalatine artery and anterior ethmoid artery is a first-line standard of care in managing intractable epistaxis, after the failure of previous packing. Epistaxis occurs in 12% of the population. Treatment is often based on nasal packing that could be poorly effective in t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.3109/00016481003621538
更新日期:2010-09-01 00:00:00
abstract:CONCLUSION:This study revealed that endolymphatic hydrops (EH) reduced in some cases with Ménière's disease (MD) treated conservatively. It appears that the EH reduction was associated with improvement of the clinical symptoms. OBJECTIVES:The relationship between the degree of EH and clinical symptoms is not clear at ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1015607
更新日期:2015-09-01 00:00:00
abstract::Fifteen normal speakers (7 women and 8 men), ranging in age from 21 to 35 years, were examined consecutively with rigid telescopy and flexible fiberscopy during sustained phonation at 3 loudness levels. The endoscopes were connected to a stroboscope and video equipment. The purpose was to investigate whether the two l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209100796
更新日期:1992-01-01 00:00:00
abstract::In the guinea pig, the organ of Corti and the spiral ganglion cells were destroyed by administering gentamicin into the inner ear. The antero-ventral cochlear nucleus (AVCN) was studied with electron microscopy 15 and 30 days after treatment. There does not seem to be a specific type of degeneration induced by the dru...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108643
更新日期:1986-07-01 00:00:00
abstract:CONCLUSION:Neck dissection (ND) may not be warranted for those patients with complete response in the neck. Human papillomavirus (HPV)-positive or -negative tumour does not affect this recommendation. OBJECTIVES:Treatment of tonsillar cancer varies considerably worldwide, although non-surgical treatment, e.g. radiothe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.920516
更新日期:2014-10-01 00:00:00
abstract::Spiral ganglia of guinea pig and mouse were investigated by scanning electron microscopy (SEM). The cochlea was freeze-fractured and then macerated with 0.1% OsO4 solution for 70-90 h (A-O-D-O method (1]. This allowed three-dimensional observation of the general view of the spiral ganglion and the intracellular struct...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127528
更新日期:1989-05-01 00:00:00
abstract:CONCLUSIONS:In our study setting nitrous oxide (N(2)O) did not show any clinical benefit in discomfort experienced when applying local anesthesia for nasal operations. Further studies with longer inhalation times are needed to elucidate the role of N(2)O in application of local anesthesia in nasal surgery. OBJECTIVES:...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016480701714319
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:Temperature-controlled radiofrequency volumetric tissue reduction (RFVTR) is a minimally invasive technique used in the treatment of the tongue base, soft palate and turbinates. Complications seem to be rare, but the scope of previous studies was often limited by the small number of patients included. The aim...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001385
更新日期:2003-05-01 00:00:00
abstract::The aerobic and anaerobic bacterial flora of middle ear exudate (MEE) of 47 consecutive patients with chronic suppurative otitis media were studied using a quantitative bacteriological technique under strictly anaerobic conditions. Specimens from the external auditory canal (EAC) and the nasopharynx (NP) were obtained...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609119425
更新日期:1986-11-01 00:00:00
abstract:CONCLUSION:Use of the Meniett pressure generator in patients with active Ménière's disease (MD) did not affect labyrinthine function. OBJECTIVE:To investigate whether application of the Meniett pressure generator in patients with active MD significantly affects their labyrinthine function. MATERIAL AND METHODS:We mea...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.1080/00016480500388869
更新日期:2006-03-01 00:00:00
abstract::The tonsils are mucosa-associated lymphoid organs. Several details regarding their normal function and pathological alteration are still unknown. In this review the relationship of the tonsils to similar lymphoid organs is discussed, the possibilities of antigen uptake (M cells and micropores of the crypt epithelium) ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:
更新日期:1987-05-01 00:00:00
abstract::The possible beneficial effects of carbogen gas (95% O2/5% CO2) inhalation on noise-induced permanent cochlear impairment were investigated. Groups of guinea pigs were exposed to daily 3 1/2-hour presentations of 120 dB of broad-band noise in an atmosphere of either carbogen gas or normal air. Other groups received ca...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130889
更新日期:1982-05-01 00:00:00
abstract::A prospective study was carried out to assess the possible biochemical background of the AAm production by HVF in accordance with selected histological types and voice disorders. The mass of new tissue forming HVF in different clinical cases led us to suspect, according to our previous results, that PGs, LTs and other...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135840
更新日期:1993-05-01 00:00:00
abstract::Background: It has been reported that head-up sleep (HUS) prevents free-floating otoliths from entering canals and that vertical recognition training (VRT) promotes vestibular compensation.Aims/objectives: We would like to assess HUS and VRT for intractable motion-evoked dizziness, including possible benign paroxysmal...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1727566
更新日期:2020-06-01 00:00:00
abstract::We previously reported that long-term exposure to glutamate (Glu) induced death of cochlear outer hair cells (OHCs). However, the mechanisms of OHC death induced by Glu were unclear. In the central nervous system, Glu is known to interfere with a cystine-Glu antiporter, leading to a decrease in cystine uptake and redu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180612
更新日期:1999-01-01 00:00:00
abstract::This report shows the changes that occurred in consecutive audiograms of a patient who underwent chemotherapy and radiotherapy for nasopharyngeal cancer and the histopathological examination of the temporal bones. Both conductive and sensorineural hearing loss developed, but followed different modes of progression. In...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480601127026
更新日期:2007-10-01 00:00:00
abstract:CONCLUSION:An 18-mer peptide derived from the neurotrophic region of prosaposin (PS-pep) prevents hearing loss and cochlear damage due to transient cochlear ischaemia by activating an anti-apoptotic pathway. PS-pep is a potent candidate molecule for alleviating ischaemia-induced hearing loss. OBJECTIVE:PS-pep was inve...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.750430
更新日期:2013-05-01 00:00:00