Arachidonic acid metabolites (AAm) synthesis by the human hypertrophic ventricular folds (HVF).

Abstract:

:A prospective study was carried out to assess the possible biochemical background of the AAm production by HVF in accordance with selected histological types and voice disorders. The mass of new tissue forming HVF in different clinical cases led us to suspect, according to our previous results, that PGs, LTs and other AAm may be involved in the pathogenesis of HVF. The level of PGE2 in HFV was lower (0.7 ng/ml) than in control (1.09 ng/ml) but not significantly; the PGI2 level (0.01 ng/ml) in HVF was also nonsignificantly lower than in normals, while thromboxane A2 synthesis by HVF (0.42 ng/ml) was significantly less than in control (0.99 ng/ml). On the basis of these results the hypothesis of a possible role of AAm in the process of HVF could not be confirmed.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Vecerina-Volić S,Klapan I

doi

10.3109/00016489309135840

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

435-8

issue

3

eissn

0001-6489

issn

1651-2251

journal_volume

113

pub_type

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