Abstract:
CONCLUSION:Contrast enhancement of the inner ear by three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) taken 4 h after intravenous gadolinium (Gd) injection was better than when taken at 10 min. Using heavily T2-weighted 3D-FLAIR MRI, visualization of endolymphatic hydrops (EH) was possible in the vestibule and the cochlea after a standard intravenous dose of Gd. OBJECTIVES:To define a suitable time point for imaging Gd uptake in the inner ear acquired with heavily T2-weighted 3D-FLAIR MRI after standard intravenous Gd administration. METHODS:Using a 3 Tesla MRI unit, heavily T2-weighted 3D-FLAIR MRI images were taken twice at approximately 10 min (conventional timing) and 4 h after intravenous gadodiamide (0.1 mmol/kg) injection in 10 patients with inner ear diseases including Ménière's disease. RESULTS:The 4 h delay increased Gd enhancement of the 3D-FLAIR MRI images of the perilymphatic space in both symptomatic and asymptomatic ears. The increase in Gd enhancement was greater in symptomatic than in asymptomatic ears. Using this heavily T2-weighted 3D-FLAIR technique, EH was observed in both the cochlea and vestibule in images taken 4 h after the intravenous Gd injection.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Sano R,Teranishi M,Yamazaki M,Isoda H,Naganawa S,Sone M,Hiramatsu M,Yoshida T,Suzuki H,Nakashima Tdoi
10.3109/00016489.2011.639085subject
Has Abstractpub_date
2012-03-01 00:00:00pages
241-6issue
3eissn
0001-6489issn
1651-2251journal_volume
132pub_type
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