Abstract:
:Volumetric changes of the scala media were histologically investigated in normal guinea pigs to see whether glycerol-induced volumetric change of the scala media followed a biphasic course similar to the auditory threshold in the glycerol test. Glycerol was administered orally in a 12 ml/kg dose. The volume of the scala media was assessed by examining the cross-sectional area of the scala media in the mid-modiolar sections of the cochlea. Histological study revealed that the time-course of the change in the volume of the scala media after glycerol intake showed biphasic changes. Specifically, the early phase of the glycerol effect is a decrease in endolymph volume. The volume of the scala media significantly decreased by 11.4+/-2.9% 2 h after glycerol intake. Thereafter, the volume began to increase, and reached its peak 6-12 h after intake. In addition, the volume of the scala media significantly increased by 17.6+/-1.1% after 6 h. The present study indicated that the secondary increase in the volume of the scala media following glycerol intake played an important role in the rebound phenomenon in the glycerol test, although the mechanism underlying the hearing loss with the endolymphatic hydrops remains to be elucidated.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Takeda T,Takeda S,Saito H,Hamada M,Sawada Sdoi
10.1080/00016489950181369subject
Has Abstractpub_date
1999-01-01 00:00:00pages
341-4issue
3eissn
0001-6489issn
1651-2251journal_volume
119pub_type
杂志文章abstract:CONCLUSION:The possible roles of CD44st, CD44v5 and CD44v6 in the prognosis of head and neck cancer deserve further elucidation and evaluation with long-term patient follow-up. OBJECTIVE:Standard CD44 (CD44st), CD44 variant 5 (CD44v5) and CD44 variant 6 (CD44v6) are expressed in human malignant cells and tissues. The ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510026971
更新日期:2005-04-01 00:00:00
abstract:CONCLUSION:This study shows that, in cochlear implantation (CI) surgery, pre-operative caloric test results are not correlated with post-operative outcomes of dizziness or speech perception. OBJECTIVES:To determine the role of pre-operative caloric tests in CI. METHODS:The records of 95 patients who underwent unilate...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1172731
更新日期:2016-09-01 00:00:00
abstract::In the guinea pig, the organ of Corti and the spiral ganglion cells were destroyed by administering gentamicin into the inner ear. The antero-ventral cochlear nucleus (AVCN) was studied with electron microscopy 15 and 30 days after treatment. There does not seem to be a specific type of degeneration induced by the dru...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108643
更新日期:1986-07-01 00:00:00
abstract::Seven to eight years after a disease period of vestibular neuritis 19 patients previously examined at our department were given a questionnaire about whether they had experienced any audiovestibular symptoms since they first fell ill. All 19 patients responded and 18 consented to participate in the long-term follow-up...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180243
更新日期:1999-01-01 00:00:00
abstract::Lymphangioscopical and ultrastructural studies of the larynx reveal a lymphatic capillary and a collecting vessel system. Collecting vessels show luminal valves and elastic structural components within the wall. Lymphangioscopy reveals that a strict compartmentation of different laryngeal areas is unjustifiable with t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127137
更新日期:1980-03-01 00:00:00
abstract::The transitional zone of the saccule and the utricle--has been studied by transmission electron microscope in rats, days before birth. A noticeable secretory activity has been observed in their cells as well as the presence of inorganic spicular bodies that have also been observed in the lumen, some of them integrated...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309139436
更新日期:1983-05-01 00:00:00
abstract:CONCLUSIONS:The transconjunctival approach to orbital floor fractures permits excellent exposure of the inferior orbit and provides a good surgical outcome, especially with regard to ocular motility. OBJECTIVE:Surgical access to orbital floor fractures can be accomplished via the transconjunctival approach. The majori...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500395757
更新日期:2006-04-01 00:00:00
abstract::A family with early-onset vestibulopathy is presented. The 34-year-old father had experienced brief attacks of vertigo and currently suffers from unsteadiness and oscillopsia during head movements. His two young sons also experience brief attacks of spontaneous vertigo. In vestibular testing all three subjects showed ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310002500
更新日期:2003-08-01 00:00:00
abstract::Organophosphorus compounds in the form of insecticides are in widespread use and have recently attracted considerable interest as environmentally toxic agents. As little is known about the effect of environmental toxins on the tubal function in the ear, we studied the middle ear pressure necessary to force the eustach...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139361
更新日期:1995-07-01 00:00:00
abstract::The use of SEM as an adjunct to TEM and electrophysiological examination of the cochlea is now well established. It has provided a relatively simple method of assessing the effect of noise, ototoxic drugs, electrical stimulation, etc. on the surface features of the organ of corti. A controlled experiment was undertake...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509126566
更新日期:1985-11-01 00:00:00
abstract::The objective of this study was to determine whether methylcobalamin inhibits the ototoxic action of gentamicin. Fourteen pigmented guinea pigs were randomly divided into experimental and control groups. Each animal in the experimental group was given a large single dose of gentamicin (125 mg/kg i.m.), followed by imm...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300102752
更新日期:2001-04-01 00:00:00
abstract::Two hundred Malaysian patients representing 227 ears with previously untreated cholesteatoma disease were analysed retrospectively in terms of i) type of disease, i.e. primary acquired attic defect or posterior superior retraction pocket and secondary acquired type cholesteatoma; ii) positive history of previous middl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138380
更新日期:1991-01-01 00:00:00
abstract::Background: Neutrophil-to-lymphocyte ratio (NLR) has emerged as a marker for degree of inflammation. Inflammation has been regarded as one of the causes of idiopathic sudden sensorineural hearing loss.Objectives: This study investigated the potential association between neutrophil-to-lymphocyte ratio (NLR) and prognos...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1705998
更新日期:2020-04-01 00:00:00
abstract::In a previous study, the authors described a technique for recording ipsilateral EABRs using the DIGISONIC MXM cochlear implant (Gallégo et al, Acta Otolaryngol (Stockh) 1996; 116: 228-33) and showed that the EABR input/output functions were very similar across electrodes. In the present study a test of electrode func...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709117761
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVE:Setting the optimal rate of stimulation for individual cochlear implant recipients is critical to the successful functional outcome of cochlear implantation. In the absence of an objective methodology, cochlear implants are currently fitted by means of a time-consuming (and therefore expensive) trial-and-erro...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310002168
更新日期:2004-08-01 00:00:00
abstract:CONCLUSION:From aspect of fluid dynamics, expanding patients' nasopharyngeal coronal-sectional area to 48.3-54.7% of normal area will bring the airflow velocity back to normal in adenoidal hypertrophy children. It might provide a suggestion for adenoidectomy range selection and whether total resection is necessary. OB...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1212266
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Li quick repositioning maneuver for treatment of geotropic horizontal canal benign paroxysmal positional vertigo (HC-BPPV) was reported in the literature. OBJECTIVE:The aim of this study is to observe the clinical efficacy of the Li quick repositioning maneuver for the treatment of geotropic HC-BPPV. METHO...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016489.2018.1476778
更新日期:2018-09-01 00:00:00
abstract::In order to examine evidence of high activity of pinocytosis in capillaries of the stria vascularis, quantitative morphometry of pinocytotic vesicles was carried out ultrastructurally by the horseradish peroxidase (HRP) tracer method. In guinea pigs, there was a significant difference between the stria vascularis and ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::Synchronous benign and malignant tumors in the ipsilateral salivary glands are extremely rare. We report a unique case of synchronous unilateral parotid tumors in a 71-year-old man. The main parotid lesion was preoperatively suggested to be adenocarcinoma by fine needle aspiration cytology. A coexisting Warthin's tumo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600606707
更新日期:2007-01-01 00:00:00
abstract:CONCLUSIONS:It has been shown that TRPMs may play a functional role in sensory cell physiology, fluid homeostasis, sensory cell death, and thermosensation in the inner ear, while TRPA1 plays an important role in sensory transduction. OBJECTIVE:To study expression of TRPM1-8 and TRPA1 in the mouse inner ear. MATERIALS...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802570545
更新日期:2009-10-01 00:00:00
abstract::Nl action potentials, elicited by low-level, 4.0-kHz filtered clicks, were recorded from the ear canals of normal-hearing adults. Responses were recorded at two sensation levels in the presence and absence of a pure tone delivered to the contralateral ear. Waveforms were analysed for changes in amplitude and latency. ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107792
更新日期:1987-05-01 00:00:00
abstract::It has previously been shown that simple compounds with multiple amine groups are ototoxic, the degree of ototoxicity depending on the number of amine groups in the molecule. The relationship between the number of amino groups and ototoxicity in aminoglycoside was studied using kanamycin A and kanamycin B, which conta...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709134700
更新日期:1987-01-01 00:00:00
abstract::The Dynamic Illegible E (DIE) test measures visual acuity with head held still while reading a specially designed visual acuity chart of E's. The head is then moved passively and the change in visual acuity is recorded. The DIE test has previously been shown to be very useful for assessing patients with aminoglycoside...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::Cells can die by two distinct pathways: apoptosis and necrosis. To explore whether intense noise can induce hair cell (HC) death via the apoptotic pathway, we systematically examined morphological changes in guinea pig cochlear HC nuclei stained with Hoechst 33342, a fluorescent dye specifically labelling the nuclear ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:CONCLUSIONS:In addition to the correlation of transforming growth factor (TGF)-beta1 levels to the radiation toxicity, both Epstein-Barr virus (EBV) infection and postoperative status play roles in the change in plasma TGF-beta1 levels in patients with head and neck cancers. OBJECTIVES:To assess the parameters involve...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701714293
更新日期:2008-10-01 00:00:00
abstract:CONCLUSION:The endoscopic transnasal approach with IGS is a safe and effective technique, allowing completely resection of JPOF, with minimal morbidity and recurrence. OBJECTIVES:JPOF is a benign but locally aggressive fibro-osseous lesion. This study presents a series of JPOF cases, involving anterior skull base and ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1276302
更新日期:2017-07-01 00:00:00
abstract:CONCLUSIONS:This study shows that heavy drinking is a risk factor for prolonged delay in presenting with head and neck cancer and for presenting with a large tumour in the head and neck region. Excessive smoking is only a risk factor for being diagnosed with a large tumour, although there is a weak association between ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510028456
更新日期:2005-05-01 00:00:00
abstract::The effects of two simulated hearing impairments (presbyacusis) on speech perception were investigated in two groups of normally hearing subjects (30 and 48 subjects, respectively). Eight patients with presbyacusis with similar hearing impairment to those in the latter simulation served as the clinical material. Word ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000991
更新日期:2000-03-01 00:00:00
abstract::The effects of two sympathomimetic drugs on mucociliary activity and mucosal blood flow in the rabbit maxillary sinus were investigated by using a photo-electric technique (mucociliary activity) and laser Doppler flowmetry (blood flow). The responses produced were compared with effects of ligation of the external caro...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809097018
更新日期:1988-03-01 00:00:00
abstract::Multimodality therapy of advanced malignant tumours of the head and neck includes surgery, radiotherapy and chemotherapy. However, the cure rate for these tumours is low and guidelines for the selection and timing of therapy are needed. For such guidelines, tumour cell kinetic parameter studies, e.g. cell proliferatio...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309130933
更新日期:1983-01-01 00:00:00