Abstract:
:Background: Neutrophil-to-lymphocyte ratio (NLR) has emerged as a marker for degree of inflammation. Inflammation has been regarded as one of the causes of idiopathic sudden sensorineural hearing loss.Objectives: This study investigated the potential association between neutrophil-to-lymphocyte ratio (NLR) and prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).Material and methods: This retrospective, case-control clinical trial analyzed data from 186 subjects diagnosed with ISSNHL and admitted to Kyung-Hee Medical Center between March 2016 and February 2019. Hematologic and audiometric parameters were measured.Results: NLR showed a linear correlation with hearing recovery in patients with ISSNHL, with hearing gain (dB) = 56.698 - 3.718 × NLR (r2 = 0.451, p = .001). Hearing recovery at all frequencies was numerically higher in patients with low (<6.661) than higher (≥6.661) NLR at all frequencies and was significantly higher at 500, 1000, 2000, 3000, and 4000 Hz. Hearing thresholds at 250, 500, 1000, 2000, 3000, and 4000 Hz in the low NLR group were significantly lower after treatment.Conclusions and significance: The ability to recover from ISSNHL decreases as NLR increases. NLR may be a valuable prognostic marker in patients with ISSNHL.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Kang JW,Kim MG,Kim SS,Im HI,Dong SH,Kim SH,Yeo SGdoi
10.1080/00016489.2019.1705998subject
Has Abstractpub_date
2020-04-01 00:00:00pages
307-313issue
4eissn
0001-6489issn
1651-2251journal_volume
140pub_type
杂志文章abstract::The nasal mucosa and the autonomic nervous regulation of protective reflexes plays an important role for the protection of the lower airways. Increasing experimental evidence from both animal models and humans suggests that the organization of the autonomic nervous pathways is more complicated than previously assumed....
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489309135832
更新日期:1993-05-01 00:00:00
abstract::Hereditary angioneurotic edema (HAE) is an autosomal dominant disease resulting from a deficiency of functional C1-esterase inhibitor. If not recognized promptly and treated properly the disease can result in a fatal outcome as it causes laryngeal edema, which can lead to a life-threatening acute upper airway obstruct...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510038185
更新日期:2005-11-01 00:00:00
abstract:UNLABELLED:Abstract Conclusions: In survival analysis, the combined Charlson comorbidity index (CCI) can be considered as a prognostic factor independent of the tumor node metastasis (TNM) classification, tumor stage, and tumor location. Severe comorbidity was the factor that had the greatest impact on prognosis in cas...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.564651
更新日期:2011-08-01 00:00:00
abstract::This study was performed in order to determine the immunohistochemical expression and distribution pattern as well as the electrophysiological actions of substance P in human vestibular ganglion cells. Substance P-like immunostaining was mainly found in the cytoplasm of small vestibular ganglion cells. In contrast, ne...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137839
更新日期:1996-03-01 00:00:00
abstract:CONCLUSIONS:Osteomas of the incus were found in surprisingly high numbers in ancient and modern populations. The coexistence of osteoma formation and unique vascularization on the medial surface of the incus alludes to a relationship between the two findings. OBJECTIVE:Osteomas involving the middle ear ossicles are ra...
journal_title:Acta oto-laryngologica
pub_type: 历史文章,杂志文章
doi:10.1080/00016480510043431
更新日期:2005-11-01 00:00:00
abstract::Patients with hemifacial spasm and trigeminal neuralgia later treated with microvascular decompression and surgical interposition for their vascular loop disturbance were investigated preoperatively with electronystagmography, saccade test and audiometry. Some of them underwent an extended investigation including comp...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809119522
更新日期:1988-05-01 00:00:00
abstract::In order to examine evidence of high activity of pinocytosis in capillaries of the stria vascularis, quantitative morphometry of pinocytotic vesicles was carried out ultrastructurally by the horseradish peroxidase (HRP) tracer method. In guinea pigs, there was a significant difference between the stria vascularis and ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::Although still the subject of discussion, vestibular-evoked myogenic potentials (VEMPs) have been considered to reflect the function of the saccular and, more recently, the cochlear tracts. To accurately determine the precise afferent pathway carrying VEMPs, we studied the outcomes of VEMPs and other examinations in p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract:CONCLUSIONS:Analysis of the complete mtDNA genome and X-linkage of this five-generation Chinese family revealed that the 1555A > G mutation may lead to deafness. OBJECTIVES:Mutations in mitochondrial DNA (mtDNA) have been found to be associated with sensorineural hearing loss. However, the variable clinical phenotype ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.575794
更新日期:2011-09-01 00:00:00
abstract:CONCLUSION:Vestibular disturbance is frequent, but mild even immediately after stapes surgery. Vestibular symptoms improved or disappeared quickly, and they did not correlate with nystagmus. Outpatient stapes surgery performed under local anaesthesia is a feasible approach. OBJECTIVE:Vestibular symptoms are common and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.782106
更新日期:2013-08-01 00:00:00
abstract::Thirty-two patients affected by idiopathic benign paroxysmal positional vertigo (BPPV) of the posterior semicircular canal were studied before, 3 days and I month after a resolutive Semont manoeuvre by means of dynamic posturography. The overall postural control in BPPV patients was shown to be impaired, as demonstrat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850183340
更新日期:1998-06-01 00:00:00
abstract::Explants of basilar papillae from 6-7 days posthatch chicks were cultured in growth medium for a period of 1-8 days. Hair cells were counted following staining of stereocilia bundles with FITC-phalloidin, and the percentage of hair cell survival was determined by comparison to control (i.e. uncultured) specimens. Hair...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850183133
更新日期:1998-09-01 00:00:00
abstract::There have been many morphological investigations on the generation of respiratory epithelium. However, the mucociliary activity of fetal respiratory epithelium has never yet been discussed. In the present work, ciliary activity and mucociliary function in the nose and the trachea of fetal rabbits were studied and, mo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409130999
更新日期:1984-03-01 00:00:00
abstract::A thorough examination of hearing and hearing loss among workers in the saw- and papermill industries in northern Sweden showed that even a serious hearing loss does not give the expected social handicap. ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609119960
更新日期:1976-03-01 00:00:00
abstract:CONCLUSION:No case of death related to surgery in the form of uvulopalatopharyngoplasty, uvulopalatoplasty or nasal surgery for snoring or sleep apnea has been recorded in Sweden among 4876 patients treated between 1997 and 2005. Severe complications of surgery in the peri- and postoperative period, especially in the f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.528793
更新日期:2011-03-01 00:00:00
abstract::In 6 pigs a bronchoscopical resection of the tracheal mucosa was performed using CO2-laser on one side, and an electric high-frequency cutting loop (ECL) on the other. The pigs were sacrificed 3 months later. On macroscopic examination the tracheal mucosa appeared almost normal on the laser-resected side, while severe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127514
更新日期:1989-03-01 00:00:00
abstract::In consecutive series of 326 laryngeal cancer patients, of 29 (9%) with stage T3N0 glottic carcinomas, 23 achieved complete local remission after curative radiotherapy and form the basis of the present investigation. Flow cytometry determinations of DNA-ploidy status and the S-phase fraction, and a "histopathological ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135796
更新日期:1993-03-01 00:00:00
abstract::Based on the experimental results of thyroplasty, thyroplasty type I which aims at medical shifting the vocal cord was performed on 8 patients with dysphonia, 6 with vocal cord paralysis and 2 with vocal cord atrophy. The surgery was conducted on either in- or out-patient basis and local anesthesia was used. Usually, ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121353
更新日期:1975-11-01 00:00:00
abstract:CONCLUSIONS:The transconjunctival approach to orbital floor fractures permits excellent exposure of the inferior orbit and provides a good surgical outcome, especially with regard to ocular motility. OBJECTIVE:Surgical access to orbital floor fractures can be accomplished via the transconjunctival approach. The majori...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500395757
更新日期:2006-04-01 00:00:00
abstract:CONCLUSION:Telephone usage is a difficult challenge for cochlear implanted patients. A significant number of cochlear implanted patients are able to carry on a land-line or mobile telephone conversation. The telephone model may be a critical factor for telephone performance. OBJECTIVES:The goals of this study were to ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500469552
更新日期:2006-07-01 00:00:00
abstract::The electromagnetic interference of the recently introduced bone-anchored hearing aid (BAHA) model "BAHA Compact" by digital cellular phones is investigated and compared with that of the older "BAHA Classic 300" model. Measurements with two different digital cellular phones in a laboratory setting indicated that the n...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480260092318
更新日期:2002-07-01 00:00:00
abstract::Background: The various pathological types of non-squamous cell carcinomas (nSCCs) of the larynx accounted for about 5% laryngeal malignancies, but the knowledge regarding these pathological behaviors, therapeutic models and prognostic factors was limited.Objectives: To investigate the clinical characteristics and the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1700305
更新日期:2020-02-01 00:00:00
abstract:CONCLUSIONS:A large series confirmation may suggest elective neck dissection in cN0 MASPIN-negative oral squamous cell carcinomas (SCCs). Re-activated nuclear MASPIN in association with anti-angiogenic or cytotoxic drugs may be extremely effective in the treatment of laryngeal SCC. OBJECTIVES:MASPIN is a serpin showin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.1080/00016480802256079
更新日期:2009-05-01 00:00:00
abstract::The most common cause of seasonal allergic rhinitis in Japan is the Japanese cedar (JC). Recently, a pullulan-conjugated antigen (CS-560) has been developed to reduce adverse effects and to enhance the effect of JC-specific immunotherapy (IT). If the mechanism of IT can be fully elucidated and the treatment can be use...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.1080/00016480252775742
更新日期:2002-01-01 00:00:00
abstract::Sigmoid sinus diverticulum-induced pulsatile tinnitus is a rare medical problem. Here we report a case where pulsatile tinnitus occurred in the perimenopause with evidence of sigmoid sinus diverticulum. The tinnitus disappeared with the restoration of hearing after surgery. While diagnosis is critical for the treatmen...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.567998
更新日期:2011-08-01 00:00:00
abstract::This paper presents the results of an investigation into the possibility that gangliosides (brain cortex glycosphingolipids) are capable of being functionally incorporated into cell membranes and of interfering with enzymatic activity of the ATPase system on the stria vascularis and spiral ligament in the guinea pig. ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109133282
更新日期:1981-11-01 00:00:00
abstract::The cochlea of the inner ear is no longer regarded exclusively as a passive mechanical signal analyser. Active mechanical processes are thought to influence the vibration pattern of the basilar membrane. The source of these active mechanical processes is sought in the outer hair cells (OHC). These auditory sensory cel...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809119443
更新日期:1988-01-01 00:00:00
abstract::The influence of cigarette smoke on the pharyngeal mucosa was investigated in a clinical study and in an experiment on animals. Histologic reports were evaluated according to the Kambic-Lenart classification of hyperplastic aberrations of the throat mucosa. A close dependence of the degree of hyperplasia and the numbe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809121433
更新日期:1978-01-01 00:00:00
abstract:CONCLUSION:Each of eight patients with bilateral microtia and atresia underwent bilateral reconstruction of the auricles and external auditory canals and were fitted bilateral canal-type hearing aids in the operated ears to replace a bone conduction hearing aid. The ability to discriminate inter-aural intensity differe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1249947
更新日期:2017-04-01 00:00:00
abstract:CONCLUSIONS:The distortion product otoacoustic emission (DPOAE) amplitudes in diabetics were significantly lower than those in controls when pure tone audiometry (PTA) was within normal limits, implying cochlear function impairment in the early stage of diabetes mellitus. Retrocochlear damage was suggested by elongated...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,meta分析,评审
doi:10.1080/00016489.2016.1223344
更新日期:2017-02-01 00:00:00